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    • News  (30)
    • Research  (42)
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    • News  (30)
    • Research  (42)
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  • October 2018 (Revised August 2023)
  • Case

Safecast: Bootstrapping Human Capital to Big Data

By: Ethan Bernstein and Stephanie Marton
On March 11, 2011, at 2:46pm, a 9.1-on-the-Richter-scale, six-minute long earthquake unleashed a tsunami that ravaged the Tohoku region of Japan, damaging the Fukushima Daiichi Nuclear Power facility and releasing sufficient radioactive material into the air and ocean... View Details
Keywords: Citizen Science; Creative Commons; Open Data; Open Architecture; Volunteer-based Organization; Fukushima Daiichi Nuclear Power Facility; 311; Nuclear; Radiation; Crowdsourcing; Bgeigie; Geiger Counters; Kickstarter; Sustainability; Sustainable Business And Innovation; Design; Energy Generation; Social Entrepreneurship; Human Capital; Innovation and Invention; Crisis Management; Organizational Structure; Organizational Design; Information Technology; Business Model; Energy Industry; Technology Industry; Japan; North and Central America; Europe
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Bernstein, Ethan, and Stephanie Marton. "Safecast: Bootstrapping Human Capital to Big Data." Harvard Business School Case 419-033, October 2018. (Revised August 2023.)
  • 18 Apr 2019
  • Research & Ideas

Open Innovation Contestants Build AI-Based Cancer Tool

Radiation therapy can be lifesaving for lung cancer patients. The first step, though, is having a trained, skilled oncologist who knows how to best segment or mark off the tumor for radiation. This expertise is vital for targeting the... View Details
Keywords: by Martha Lagace; Health; Medical Devices & Supplies
  • September 2012
  • Supplement

Intraoperative Radiotherapy for Breast Cancer (B)

By: Willy Shih
The intraoperative radiotherapy (IORT) business at Carl Zeiss Meditec had struggled with growth since the time of the (A) case. Though the unit had grown revenues in excess of 50% and had exceeded its EBIT target, it faced several key strategic choices. Should it... View Details
Keywords: Radiotherapy; Breast Cancer; Brachytherapy; Therapeutic Radiation; Oncology; Oncology Treatment Systems; Elekta AB; Varian Medical Systems; Xoft; Electronic Brachytherapy; Intraoperative Radiotherapy; Disruptive Innovation; Health Care and Treatment; Entrepreneurship; Technological Innovation; Growth and Development Strategy; Health Industry; Germany
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Shih, Willy. "Intraoperative Radiotherapy for Breast Cancer (B)." Harvard Business School Supplement 613-040, September 2012.
  • September 2014
  • Article

Defining the Value of Proton Therapy Using Time-Driven Activity-Based Costing

By: N.G. Thaker, A.B. Guzman, Thomas W. Feeley, T.M. Jones, J.R. Incalcaterra, C. Kolom, S.J. Frank, L.S. Tatum, Ronald S. Walters, Scott B. Cantor, D.I. Rosenthal, A.S. Garden, G.B. Gunn, C.D. Fuller and M.B. Palmer
Technological innovations in radiation therapy (RT) have rapidly improved the quality of care for patients with head and neck cancer. Intensity-modulated proton therapy (MPT) holds promise of further improving outcomes compared with the current photon-based technique... View Details
Keywords: Time-Driven Activity-Based Costing; Health Care and Treatment; Technological Innovation; Activity Based Costing and Management
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Thaker, N.G., A.B. Guzman, Thomas W. Feeley, T.M. Jones, J.R. Incalcaterra, C. Kolom, S.J. Frank, L.S. Tatum, Ronald S. Walters, Scott B. Cantor, D.I. Rosenthal, A.S. Garden, G.B. Gunn, C.D. Fuller, and M.B. Palmer. "Defining the Value of Proton Therapy Using Time-Driven Activity-Based Costing." Oncology Payers, no. 1 (September 2014): 22–28.
  • August 2023
  • Case

Augmenix: Space to Think Differently

By: Satish Tadikonda and Sidhant Jena
Amar Sawhney, a serial medtech entrepreneur, had founded Augmenix to develop and commercialize a hydrogel-based medical device called SpaceOAR as an adjunctive technology to core radiation therapy. This technology was used to protect organs at risk (OAR) during... View Details
Keywords: Entrepreneurship; Health Care and Treatment; Technology Adoption; Innovation Strategy; Technological Innovation; Product Development; Commercialization; Medical Devices and Supplies Industry
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Tadikonda, Satish, and Sidhant Jena. "Augmenix: Space to Think Differently." Harvard Business School Case 824-031, August 2023.
  • Article

Time-Driven Activity-Based Costing in Breast Cancer Care Delivery

By: Navraj S. Nagra, Elena Tsangaris, Jessica Means, Michael J. Hassett, Laura S. Dominici, Jennifer R. Bellon, Justin Broyles, Robert S. Kaplan, Thomas W. Feeley and Andrea L. Pusic
We used time-driven activity-based costing (TDABC) to calculate the complete cost of breast cancer care—initial treatment planning, chemotherapy, radiation therapy, surgical resection and reconstruction, and ancillary services (psychosocial oncology, physical therapy.... View Details
Keywords: Healthcare; Time-Driven Activity-Based Costing; Health Care and Treatment; Cost
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Nagra, Navraj S., Elena Tsangaris, Jessica Means, Michael J. Hassett, Laura S. Dominici, Jennifer R. Bellon, Justin Broyles, Robert S. Kaplan, Thomas W. Feeley, and Andrea L. Pusic. "Time-Driven Activity-Based Costing in Breast Cancer Care Delivery." Annals of Surgical Oncology 29, no. 1 (January 2022): 510–521.
  • November 15, 2021
  • Article

Putting Your Corporate Purpose to Work

By: Hubert Joly
Making a company purpose come to life is an arduous journey that requires a multi-pronged and sustained approach. Yet as hard as it is, the journey is well worth it and will yield positive transformation not only for the company, but also for the people who work there.... View Details
Keywords: Organizations; Mission and Purpose; Corporate Strategy; Management Practices and Processes; Organizational Culture; Business and Stakeholder Relations
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Joly, Hubert. "Putting Your Corporate Purpose to Work." Harvard Business Review (website) (November 15, 2021).
  • January 2001 (Revised July 2003)
  • Case

Pharmacyclics: Financing Research & Development

By: Malcolm P. Baker, Richard S. Ruback and Aldo Sesia
Pharmacyclics (NASDAQ: PCYC), a pharmaceutical company that manufactures products that will improve existing therapeutic treatments for cancer, arteriosclerosis, and retinal disease, was considering a $60 million private placement in February 2000. The company had more... View Details
Keywords: Valuation; Cash Flow; Financing and Loans; Business Startups; Financial Strategy; Medical Devices and Supplies Industry; Pharmaceutical Industry; Health Industry
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Baker, Malcolm P., Richard S. Ruback, and Aldo Sesia. "Pharmacyclics: Financing Research & Development." Harvard Business School Case 201-056, January 2001. (Revised July 2003.)
  • July 2024
  • Case

ZEISS: Commercializing Science

By: Maria P. Roche, Carlota Moniz and Daniela Beyersdorfer
Karl Lamprecht, President and CEO of the ZEISS AG Group, mused on how far ZEISS had come in 175 years of being a pioneer in optics, and how the course he had charted since taking the helm of the company could keep it on track. In his role, he oversaw the four core... View Details
Keywords: Business Model; Business Organization; Decisions; Business Strategy; Competition; Business History; Collaborative Innovation and Invention; Independent Innovation and Invention; Disruptive Innovation; Innovation and Management; Innovation Strategy; Technological Innovation; Growth and Development Strategy; Knowledge Sharing; Industry Growth; Monopoly; Organizational Culture; Supply Chain Management; Partners and Partnerships; Risk and Uncertainty; Adaptation; Commercialization; Resource Allocation; Corporate Strategy; Semiconductor Industry; Technology Industry; Germany; Europe
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Roche, Maria P., Carlota Moniz, and Daniela Beyersdorfer. "ZEISS: Commercializing Science." Harvard Business School Case 725-359, July 2024.
  • 22 Mar 2021
  • Research & Ideas

How to Learn from the Big Mistake You Almost Make

and express the value of resilience to their teams, the likelihood that workers will report such incidents increases. That was the main finding of Resilience vs. Vulnerability: Psychological Safety and Reporting of Near Misses with Varying Proximity to Harm in View Details
Keywords: by Kristen Senz; Health
  • 26 Jun 2020
  • Research & Ideas

Why Japanese Businesses Are So Good at Surviving Crises

exposure to radiation was unlikely. Truck drivers were refusing to deliver supplies to the city. Niinami intuitively understood that reopening a convenience store there would bring back a sense of normalcy and create hope for the city’s... View Details
Keywords: by Dina Gerdeman
  • 19 Apr 2004
  • Research & Ideas

Birth of the American Salesman

pots and pans and numerous other items, became chairman of Alcoa. Edward Prizer, who became president of Vacuum Oil in 1918, made his reputation by organizing the firm's domestic and foreign sales operations. Clarence Mott Woolley, president of the American View Details
Keywords: by Laura Linard
  • 07 May 2020
  • Research & Ideas

The One Good Thing Caused by COVID-19: Innovation

mitigating the risk of contagion. Other examples of this in the past have been less extreme, but include, for example, medical device advancement developed in response to a rise in consumer awareness of radiation risk. We recently... View Details
Keywords: by Hong Luo and Alberto Galasso
  • 29 Oct 2019
  • Sharpening Your Skills

Robots in the Boardroom

effective targets. Open Innovation Contestants Build AI-Based Cancer ToolRadiation oncologists are few in number, especially if you are nowhere near a cancer facility. Could artificial intelligence be used to deliver an oncologist's skills for View Details
Keywords: by Sean Silverthorne
  • 23 Mar 2020
  • Research & Ideas

Product Disasters Can Be Fertile Ground for Innovation

In 2009, a stroke victim at a Los Angeles medical center started losing his hair following a CT brain perfusion scan. After some confusion, doctors determined he had been subject to a radiation overdose—a serious accident that might lead... View Details
Keywords: by Michael Blanding; Health; Medical Devices & Supplies
  • 05 Apr 2017
  • Research & Ideas

For Women Especially, It Pays to Know What Car Repairs Should Cost

professor in the Marketing Unit at Harvard Business School, and Meghan Busse and Florian Zettelmeyer, both professors at Northwestern University. Somewhere, a radiator leaks For the study, “mystery shoppers” posing as consumers contacted... View Details
Keywords: by Wendy Guild Swearingen; Auto; Service
  • 16 Oct 2013
  • Op-Ed

Response to Readers: Combating Climate Change with Nuclear Power and Fracking

With more than 7,500 views and 180-plus tweets, I want to thank everyone for taking the time to read the original HBS Working Knowledge piece, The Case for Combating Climate Change with Nuclear Power and Fracking, and, in particular, for sharing your thoughts with one... View Details
Keywords: by Joe Lassiter; Energy; Utilities
  • 01 Sep 2015
  • First Look

First Look -- September 1, 2015

https://www.hbs.edu/faculty/Pages/item.aspx?num=49520 2015 Journal of Comparative Effectiveness Research Comparative Costs of Advanced Proton and Photon Radiation Therapies: Lessons from Time-driven Activity-based Costing in Head and Neck... View Details
Keywords: Sean Silverthorne
  • 01 May 2018
  • First Look

First Look at New Research and Ideas, May 1, 2018

first time that the institutional investors will be seeing this new capability? Purchase this case: https://cb.hbsp.harvard.edu/cbmp/product/818020 Harvard Business School Case 313-073 Note on Radiation Therapy, Stereotaxis, and... View Details
Keywords: Sean Silverthorne
  • 01 Apr 2015
  • Research & Ideas

The Slow, Steady Battle to Fix Cancer Care

1996. "Unlike traditional health care organizations, we're organized around the type of cancer that the patient has," says Feeley. "So if you come to our thoracic center with lung cancer, you can see a medical oncologist, a surgical oncologist, a View Details
Keywords: by Carmen Nobel; Health
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