Publications

November–December 2015
Article

Active Postmarketing Drug Surveillance for Multiple Adverse Events

By: Joel Goh, Margrét V. Bjarnadóttir, Mohsen Bayati and Stefanos A. Zenios

Postmarketing drug surveillance is the process of monitoring the adverse events of pharmaceutical or medical devices after they are approved by the appropriate regulatory authorities. Historically, such surveillance was based on voluntary reports by medical... View Details

Keywords: Drug Surveillance; Health Care; Stochastic Models; Queueing; Diffusion Approximation; Brownian Motion; Health Care and Treatment; Analytics and Data Science; Analysis

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March 2009 (Revised July 2010)
Case

State Street Corporation

By: William E. Fruhan

To maximize their effectiveness, color cases should be printed in color. State Street Corp. reports a 13% gain in EPS in 2008 amidst a global financial crisis. The stock price declines 59% on the day of the earnings report. This one day decline was exceeded in the... View Details

Keywords: Fair Value Accounting; Financial Reporting; Financial Crisis; Financial Liquidity; Financial Markets; Crisis Management; Financial Services Industry

September 2020
Article

Medicaid Work Requirements in Arkansas: Two-Year Impacts on Coverage, Employment, and Affordability of Care

By: Benjamin D. Sommers, Lucy Chen, Robert J. Blendon, E. John Orav and Arnold M. Epstein

In June 2018 Arkansas became the first U.S. state to implement work requirements in Medicaid, requiring adults ages 30–49 to work twenty hours a week, participate in “community engagement” activities, or qualify for an exemption to maintain coverage. By April 2019,... View Details

Keywords: Medicaid; Health Care Policy; Health; Health Care and Treatment; Policy; Insurance; Health Industry; Arkansas

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2019
Article

Time-Driven Activity-Based Cost Analysis for Outpatient Anticoagulation Therapy: Direct Costs in a Primary Care Setting with Optimal Performance

By: Robert S. Kaplan, Rohit A. Bobade, Richard A. Helmers, Thomas M. Jaeger, Laura J. Odell and Derek A. Haas

Objectives: To determine how overall cost of anticoagulation therapy for warfarin compares with that of Novel Oral Anticoagulants (NOACs). Also, to demonstrate a scientific, comprehensive, and an analytical approach to estimate direct costs involved in monitoring and... View Details

Keywords: Time-Driven Activity-Based Costing; Activity Based Costing and Management; Health Care and Treatment; Analysis

May 2021
Case

Inclusive Innovation at Mass General Brigham

By: Katherine Baldiga Coffman and Olivia Hull

Massachusetts General Brigham (MGB) Chief Innovation Officer Christopher Coburn had overseen a period of exciting transformation and growth in healthcare innovation at MGB. In November 2019, the health system was the largest recipient of National Institutes of Health... View Details

February 2014
Teaching Note

Olympus (A)

By: Jay W. Lorsch and Suraj Srinivasan

As 2012 approached the woes of the financial crisis seemed to be fading, companies were resuming business as usual and some of the scrutiny on corporate governance practices began to recede as well. That is until another major financial scandal emerged in Japan in the... View Details

Keywords: Accounting; Corporate Governance; Corporate Accountability; Electronics Industry; Japan

2025
Working Paper

Tax Planning, Illiquidity, and Credit Risks: Evidence from DeFi Lending

By: Lisa De Simone, Peiyi Jin and Daniel Rabetti

This study establishes a plausible causal link between tax-planning-induced illiquidity and credit risks in lending markets. Exploiting an exogenous tax shock imposed by the Internal Revenue Service (IRS) on cryptocurrency gains, along with millions of transactions in... View Details

Keywords: Cryptocurrency; Taxation; Financial Liquidity; Credit; Financing and Loans; Financial Markets

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26 Mar 2014
Research & Ideas

How Electronic Patient Records Can Slow Doctor Productivity

care providers who demonstrate "meaningful use" of digital records. The legislation came from the belief that EHRs used in certain ways—such as medication order entry that would alert a clinician about drug-to-drug interactions—could... View Details

Keywords: by Dina Gerdeman; Health

August 2003 (Revised August 2024)
Case

Fighting the Battle of the Bulge—Evaluating Do Good/Do Well Innovations in Morbid Obesity Treatment

By: Regina E. Herzlinger and John McDonough

Many health care innovations appear successful; but fail. This is the first case in the Innovating Health Care course that investigates how to create successful health care innovations. It is part of the first module in the course. This module focuses on how to... View Details

Keywords: Three Pillars; Industry Analysis; Health Care and Treatment; Innovation and Invention; Innovation and Management; Medical Specialties; Health Industry

November 2005 (Revised December 2006)
Case

Jeanette Clough at Mount Auburn Hospital

Jeanette Clough, the CEO of Mt. Auburn Hospital, successfully leads a turnaround for the struggling local hospital. When she assumed leadership of Mt. Auburn in 1998, the hospital had recently suffered a $10 million loss. During her first six months, several members of... View Details

Keywords: Organizational Change and Adaptation; Change Management; Leading Change; Expansion; Health Care and Treatment; Business and Community Relations; Health Industry; Cambridge

15 Jan 2019
First Look

New Research and Ideas, January 15, 2019

forthcoming American Journal of Therapeutics Food and Drug Administration Guidance Documents and New Medical Devices: The Case of Breast Prostheses By: Weitzman, Rachel E., Ariel Dora Stern, and Daniel B. Kramer Abstract—No abstract... View Details

Keywords: Dina Gerdeman

01 Oct 2009
Working Paper Summaries

Systemic Risk and the Refinancing Ratchet Effect

Keywords: by Amir E. Khandani, Andrew W. Lo & Robert C. Merton; Construction; Real Estate

09 Jun 2015
First Look

First Look: June 9, 2015

instance, estimates of U.S. annual losses indicate $1 trillion paid in bribes, $270 billion lost due to unreported income, as well as $42 billion lost in retail due to shoplifting and employee theft. In this article we draw on insights... View Details

Keywords: Sean Silverthorne

February 2010
Article

Input Constraints and the Efficiency of Entry: Lessons from Cardiac Surgery

By: David M. Cutler, Robert S. Huckman and Jonathan T. Kolstad

Prior studies suggest that, with elastically supplied inputs, free entry may lead to an inefficiently high number of firms in equilibrium. Under input scarcity, however, the welfare loss from free entry is reduced. Further, free entry may increase use of high-quality... View Details

Keywords: Government Legislation; Health Care and Treatment; Medical Specialties; Market Entry and Exit; Welfare; Health Industry; Pennsylvania

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2009
Working Paper

Input Constraints and the Efficiency of Entry: Lessons from Cardiac Surgery

By: David M. Cutler, Robert S. Huckman and Jonathan T. Kolstad

Prior studies suggest that, with elastically supplied inputs, free entry may lead to an inefficiently high number of firms in equilibrium. Under input scarcity, however, the welfare loss from free entry is reduced. Further, free entry may increase use of high-quality... View Details

Keywords: Government Legislation; Health Care and Treatment; Medical Specialties; Market Entry and Exit; Welfare; Health Industry; Pennsylvania

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29 Jun 2010
First Look

First Look: June 29

fragile, even without leverage, precisely because the volume of new claims is excessive. Purchase the paper from SSRN ($5): http://papers.nber.org/papers/W16068 Cases & Course MaterialsVirginia Mason Medical Center (Abridged)... View Details

Keywords: Martha Lagace

March 2024 (Revised July 2024)
Case

WeightWatchers: Promoting Weight Health

By: Ranjay Gulati, Cynthia A. Montgomery, Ashley Whillans, Allison Ciechanover and Emily Grandjean

In December 2023, the 60-year-old weight management industry stalwart WeightWatchers announced the launch of WeightWatchers Clinic, which incorporated GLP-1s , a new class of prescription weight-loss medications, into the company’s portfolio of products and mobile app... View Details

Keywords: Business Strategy; Competitive Strategy; Resource Allocation; Diversification; Leadership; Growth and Development Strategy; Technology Industry; Health Industry; Pharmaceutical Industry; United States; New York (city, NY)