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    • All HBS Web  (419)
      • Faculty Publications  (55)

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      • September–October 2020
      • Article

      The Past, Present, and (Near) Future of Gene Therapy and Gene Editing

      By: Julia Pian, Amitabh Chandra and Ariel Dora Stern
      Emerging gene therapy and gene-editing technologies will have a growing impact on patient lives and health-care delivery. We analyzed a decade of data on clinical trials and venture capital investments to understand the likely trajectory of genetically focused... View Details
      Keywords: Gene Therapy; Gene Editing; Impact; Health Care and Treatment; Technological Innovation; Health Testing and Trials; Venture Capital; Change
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      Pian, Julia, Amitabh Chandra, and Ariel Dora Stern. "The Past, Present, and (Near) Future of Gene Therapy and Gene Editing." NEJM Catalyst Innovations in Care Delivery 1, no. 5 (September–October 2020).
      • December 2019 (Revised September 2020)
      • Case

      Facebook Faces the Regulators

      By: Debora L. Spar
      In the fall of 2019, Facebook and its CEO Mark Zuckerberg are facing increased scrutiny on multiple fronts. Regulators from around the globe are threatening the company with punitive measures. Users are organizing against it. But there is little consensus around what,... View Details
      Keywords: Facebook; Regulation; Media; Internet and the Web; Governance; Governing Rules, Regulations, and Reforms; Business and Government Relations; Social Media; Europe
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      Spar, Debora L. "Facebook Faces the Regulators." Harvard Business School Case 720-019, December 2019. (Revised September 2020.)
      • September 2019
      • Article

      Technology Reemergence: Creating New Value for Old Technologies in Swiss Mechanical Watchmaking, 1970-2008

      By: Ryan Raffaelli
      In 1983, 14 years after the introduction of the battery-powered quartz watch, mechanical watches and the Swiss watchmakers who built them were predicted to be obsolete (Landes, 1983). Unexpectedly, however, by 2008 the Swiss mechanical watchmaking industry had... View Details
      Keywords: Technology Reemergence; Technology Cycles; Cognition And Market Redefinition; Legacy Technology Trajectories; Information Technology; Demand and Consumers; Organizational Change and Adaptation; Identity; Change; Consumer Products Industry; Switzerland
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      Raffaelli, Ryan. "Technology Reemergence: Creating New Value for Old Technologies in Swiss Mechanical Watchmaking, 1970-2008." Administrative Science Quarterly 64, no. 3 (September 2019): 576–618.
      • October 2018 (Revised September 2020)
      • Case

      Testing Autonomy in Pittsburgh

      By: Mitchell Weiss and Brittany Urick
      Pittsburgh’s mayor had been among the first to welcome self-driving vehicles but was now one of many needing to react after a pedestrian fatality involving an autonomous Uber in Arizona. He had originally preferred to roll out “the red carpet” instead of the “red... View Details
      Keywords: Public Entrepreneurship; Government Innovation; Government Experimentation; Autonomous Vehicles; Mayor; Mayor Peduto; Cities; Mobility; Automation; Uber; Argo Ai; Aurora Innovation; Aptiv; Entrepreneurship; Public Sector; Innovation and Invention; Transportation; City; Safety; Business and Government Relations; Transportation Industry; Auto Industry; United States; Pennsylvania; Pittsburgh
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      Weiss, Mitchell, and Brittany Urick. "Testing Autonomy in Pittsburgh." Harvard Business School Case 819-059, October 2018. (Revised September 2020.)
      • August 2018
      • Case

      Christine Lagarde

      By: Julie Battilana, Carin-Isabel Knoop, Vanessa Ampelas and Noemie Assenat
      For a modular presentation of the same material, please see “Christine Lagarde (A): A French Prime Minister Calls” (HBS No. 419-017), “Christine Lagarde (B): Being a Public Servant” (HBS No. 419-018), and “Christine Lagarde (C): Managing the IMF” (HBS No. 419-019).... View Details
      Keywords: Change; Personal Development and Career; Power and Influence; Leadership; Gender; Leading Change
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      Battilana, Julie, Carin-Isabel Knoop, Vanessa Ampelas, and Noemie Assenat. "Christine Lagarde." Harvard Business School Case 419-016, August 2018.
      • 2018
      • Book

      Driving Digital Strategy: A Guide to Reimagining Your Business

      By: Sunil Gupta
      Disruption and transformation get a lot of hype and for good reason. Digital technologies have disrupted entire industries and incumbents have often struggled in this new world. Typical approaches used by legacy players such as using technology to improve efficiency,... View Details
      Keywords: Marketing; Information Technology; Transformation; Strategy; Competitive Advantage; Value Creation; Customer Focus and Relationships; Organizational Structure; Digital Strategy
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      Gupta, Sunil. Driving Digital Strategy: A Guide to Reimagining Your Business. Boston: Harvard Business Review Press, 2018.
      • June 2018
      • Case

      Meridian Systems

      By: Frank V. Cespedes and Michael J. Roberts
      The Meridian Systems case focuses on a start-up in the restaurant point of sale (POS) systems market. In early 2018, Meridian is getting ready to roll out a POS system based on a new technology—a tablet-based, Wi-Fi-enabled POS system (the "tablet" system, or... View Details
      Keywords: Business Startups; Sales; Strategy; Salesforce Management; Organizational Structure; Technological Innovation; Marketing Strategy
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      Cespedes, Frank V., and Michael J. Roberts. "Meridian Systems." Harvard Business School Brief Case 918-533, June 2018.
      • September 2017
      • Case

      Christine Lagarde

      By: Julie Battilana, Carin-Isabel Knoop, Vanessa Ampelas and Noemie Assenat
      The case covers the youth and career trajectory of Christine Lagarde across her time at Baker & McKenzie, as a minister in the government of France and as the head of the International Monetary Fund (IMF). The case highlights the challenges and opportunities she faced... View Details
      Keywords: Change; Personal Development and Career; Power and Influence; Leadership; Gender; Leading Change
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      Battilana, Julie, Carin-Isabel Knoop, Vanessa Ampelas, and Noemie Assenat. "Christine Lagarde." Harvard Business School Case 418-007, September 2017.
      • April 2017 (Revised August 2018)
      • Case

      The U.S. Shale Revolution: Global Rebalancing?

      By: Laura Alfaro and Richard H.K. Vietor
      The American shale revolution has upended oil and gas markets for nearly a decade. Prices have risen then plunged, production has surged and then waned, LNG has boomed, and technology and productivity have improved. The U.S. energy policy, under the Obama... View Details
      Keywords: Shale Oil; Shale Gas; LNG; Energy Policy; Drilling Technology; Energy; Trade; Economics; Macroeconomics; Policy; Energy Industry; Manufacturing Industry; United States; Middle East
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      Alfaro, Laura, and Richard H.K. Vietor. "The U.S. Shale Revolution: Global Rebalancing?" Harvard Business School Case 717-056, April 2017. (Revised August 2018.)
      • January 2017 (Revised March 2017)
      • Case

      IBM Transforming, 2012–2016: Ginni Rometty Steers Watson

      By: Rosabeth Moss Kanter and Jonathan Cohen
      To transform IBM for the next technology wave, Ginni Rometty, who became CEO in 2012, led divestment of declining businesses, made acquisitions in digital innovation and cloud computing, formed partnerships with former competitors such as Apple and tech startups, and... View Details
      Keywords: Digital; Technological Change; Artificial Intelligence; Data; IBM; Watson; Internet Of Things; Innovation and Invention; Management; Sales; Information Technology; Technological Innovation; Transformation; AI and Machine Learning
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      Kanter, Rosabeth Moss, and Jonathan Cohen. "IBM Transforming, 2012–2016: Ginni Rometty Steers Watson." Harvard Business School Case 317-046, January 2017. (Revised March 2017.)
      • April 2016
      • Teaching Note

      Whither the Weather (Company): Forecasting 2016

      By: Rosabeth Moss Kanter and Jonathan Cohen
      This Note was created for the purpose of aiding classroom instructors in the use of the Harvard Business School case, "Whither the Weather (Company): Forecasting 2016." As chairman and CEO, David Kenny guided the Weather Company's transformation from a cable television... View Details
      Keywords: Weather Company; IBM; Digital; Technology; David Kenny; Television; Weather Channel; Legacy Business; Mainstream; Newstream; Reorganization; Acquisitions; Transformation; Information Technology; Television Entertainment; Acquisition; Consolidation; Change; Leadership
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      Kanter, Rosabeth Moss, and Jonathan Cohen. "Whither the Weather (Company): Forecasting 2016." Harvard Business School Teaching Note 316-161, April 2016.
      • February 2016 (Revised February 2018)
      • Case

      Weathering the Storm at NYU Langone Medical Center

      By: Robert S. Huckman, Raffaella Sadun and Michael Norris
      In the fall of 2012, Hurricane Sandy forced a full evacuation of NYU Langone Medical Center in New York City. The institution, which comprised NYU Medical School and several teaching hospitals, had been on an upward trajectory for several years under the leadership of... View Details
      Keywords: Health Care; Technology; Culture; Information Technology; Crisis Management; Health Care and Treatment; Organizational Culture; Health Industry; United States; New York (city, NY)
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      Huckman, Robert S., Raffaella Sadun, and Michael Norris. "Weathering the Storm at NYU Langone Medical Center." Harvard Business School Case 616-026, February 2016. (Revised February 2018.)
      • January 2016 (Revised March 2016)
      • Case

      Whither the Weather (Company): Forecasting 2016

      By: Rosabeth Moss Kanter and Jonathan Cohen
      CEO David Kenny led the transformation of the Weather Company from a television business to a Big Data technology company from 2012 until 2016, when IBM acquired its digital assets. This case discusses major decisions taken by Kenny starting in 2014 as he sought to... View Details
      Keywords: Weather Company; IBM; Digital; Technology; David Kenny; Television; Weather Channel; Legacy Business; Mainstream; Newstream; Reorganization; Acquisitions; Transformation; Information Technology; Television Entertainment; Acquisition; Consolidation; Change; Leadership
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      Kanter, Rosabeth Moss, and Jonathan Cohen. "Whither the Weather (Company): Forecasting 2016." Harvard Business School Case 316-143, January 2016. (Revised March 2016.)
      • August 2015
      • Case

      Yabbly (A)

      By: Shikhar Ghosh and Christopher Payton
      In November 2013, with less than 10 months of cash on hand, Tom Leung, the founder and CEO of Yabbly, must decide where to focus his resources. His startup, a question-and-answer application for shopping decisions, had benefited from a strong showing at the SXSW... View Details
      Keywords: Startup; Mobile; Online Product Reviews; Consumer Products; Business Model; Business Plan; Business Startups; Entrepreneurship; Innovation Strategy; Mobile and Wireless Technology; Internet and the Web; North America; United States; Washington (state, US); Seattle
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      Ghosh, Shikhar, and Christopher Payton. "Yabbly (A)." Harvard Business School Case 816-030, August 2015.
      • 2015
      • Chapter

      Innovation and Entrepreneurship in Renewable Energy

      By: Ramana Nanda, Ken Younge and Lee Fleming
      We document three facts related to innovation and entrepreneurship in renewable energy. Using data from the U.S. Patent and Trademark Office, we first show that patenting in renewable energy remains highly concentrated in a few large energy firms. In 2009, the top 20... View Details
      Keywords: Entrepreneurial Finance; Entrepreneurial Management; Energy; Finance; Entrepreneurship; Energy Industry
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      Nanda, Ramana, Ken Younge, and Lee Fleming. "Innovation and Entrepreneurship in Renewable Energy." Chap. 7 in The Changing Frontier: Rethinking Science and Innovation Policy, edited by Adam Jaffe and Benjamin Jones, 199–232. University of Chicago Press, 2015.
      • June 2015 (Revised November 2015)
      • Case

      Akbank: Options in Digital Banking

      By: Rajiv Lal and Esel Çekin
      This case discusses the digitalization strategies of a leading bank in Turkey, Akbank, and how to position its digital banking products going forward. The Turkish banking industry was undergoing a transformation prompted by the demands of the country's digitally savvy,... View Details
      Keywords: Marketing; Banking; Emerging Market; Regulations; Channels; Digitization; Information Technology; Competition; Brands and Branding; Organizational Change and Adaptation; Emerging Markets; Distribution Channels; Banks and Banking; Digital Transformation; Banking Industry; Financial Services Industry; Turkey
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      Lal, Rajiv, and Esel Çekin. "Akbank: Options in Digital Banking." Harvard Business School Case 515-115, June 2015. (Revised November 2015.)
      • December 2014 (Revised August 2015)
      • Case

      Improving Melanoma Screening: MELA Sciences

      By: Regina E. Herzlinger, Kevin Schulman and Frédéric Dijols
      MELA is a start-up medical device company looking to develop a novel technology to help physicians diagnose a deadly skin cancer, melanoma. The case reviews the FDA medical device development process, the development path pursued by MELA, and the regulatory and... View Details
      Keywords: Healthcare Industry; Health Care; Health; Health Care and Treatment; Health Testing and Trials; Health Industry; United States
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      Herzlinger, Regina E., Kevin Schulman, and Frédéric Dijols. "Improving Melanoma Screening: MELA Sciences." Harvard Business School Case 315-042, December 2014. (Revised August 2015.)
      • Article

      Did Bank Distress Stifle Innovation During the Great Depression?

      By: Ramana Nanda and Tom Nicholas
      We find a negative relationship between bank distress and the level, quality, and trajectory of firm-level innovation during the Great Depression, particularly for R&D firms operating in capital intensive industries. However, we also show that because a sufficient... View Details
      Keywords: Great Depression; R&D; Bank Distress; Patents; Research and Development; Financial Crisis; Banks and Banking; Innovation and Invention; Banking Industry; United States
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      Nanda, Ramana, and Tom Nicholas. "Did Bank Distress Stifle Innovation During the Great Depression?" Journal of Financial Economics 114, no. 2 (November 2014): 273–292.
      • September 2012
      • Supplement

      Industrial Metrology: Getting In-Line? (B)

      By: Willy Shih
      Rainer Ohnheiser, the President of Carl Zeiss's Business Group Industrial Metrology (IMT), was focused on the threat that in-line metrology posed to Carl Zeiss IMT's core business. Historically, coordinate measurement machines (CMMs) that employed tactile measurement... View Details
      Keywords: Performance Trajectories; Emerging Technologies; Manufacturing Tools; Carl Zeiss; Go-to-market Strategy; Disruptive Innovation; Technological Innovation; Production; Performance Improvement; Measurement and Metrics; Manufacturing Industry; Germany
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      Shih, Willy. "Industrial Metrology: Getting In-Line? (B)." Harvard Business School Supplement 613-041, September 2012.
      • June 2012 (Revised August 2013)
      • Case

      Driving Towards a Disruption?

      By: Willy Shih and William Noble
      As Clayton Christensen drove to the studio to deliver an online executive education class, he pondered the future of management education. How big a threat did online degree programs, corporate universities, and other innovations in the delivery of management training... View Details
      Keywords: Disruptive Technology; Performance Trajectories; Disruptive Innovations; Business Education; Business School; Internet And Online Services Industries; Disruptive Innovation; Higher Education; Corporate Strategy; Internet; Performance; Education Industry; Boston
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      Shih, Willy, and William Noble. "Driving Towards a Disruption?" Harvard Business School Case 612-101, June 2012. (Revised August 2013.)
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