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  • September 2023 (Revised April 2024)
  • Case

Atomwise: Strategic Opportunities in AI for Pharma

By: Satish Tadikonda
Abraham Heifets and his co-founder, Izhar Wallach, had founded Atomwise to develop i) an AI engine to transform drug discovery by creating better medicines faster, and ii) a machine learning-based discovery engine that combined the power of convolutional neural... View Details
Keywords: Business Model; Business Startups; AI and Machine Learning; Science-Based Business; Technological Innovation; Biotechnology Industry; Pharmaceutical Industry
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  • Article

Pattern Detection in the Activation Space for Identifying Synthesized Content

By: Celia Cintas, Skyler Speakman, Girmaw Abebe Tadesse, Victor Akinwande, Edward McFowland III and Komminist Weldemariam
Generative Adversarial Networks (GANs) have recently achieved unprecedented success in photo-realistic image synthesis from low-dimensional random noise. The ability to synthesize high-quality content at a large scale brings potential risks as the generated samples may... View Details
Keywords: Subset Scanning; Generative Models; Synthetic Content Detection
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  • Article

Machine Learning Approaches to Facial and Text Analysis: Discovering CEO Oral Communication Styles

By: Prithwiraj Choudhury, Dan Wang, Natalie A. Carlson and Tarun Khanna
We demonstrate how a novel synthesis of three methods—(1) unsupervised topic modeling of text data to generate new measures of textual variance, (2) sentiment analysis of text data, and (3) supervised ML coding of facial images with a cutting-edge convolutional neural... View Details
Keywords: CEOs; Communication Style; Machine Learning; Spoken Communication; Nonverbal Communication; Personal Characteristics; Analysis; Performance
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  • September 15, 2021
  • Article

Improving Deconvolution Methods in Biology Through Open Innovation Competitions: An Application to the Connectivity Map

By: Andrea Blasco, Ted Natoli, Michael G. Endres, Rinat A. Sergeev, Steven Randazzo, Jin Hyun Paik, N.J. Maximilian Macaluso, Rajiv Narayan, Xiaodong Lu, David Peck, Karim R. Lakhani and Aravind Subramanian
A recurring problem in biomedical research is how to isolate signals of distinct populations (cell types, tissues, and genes) from composite measures obtained by a single analyte or sensor. Existing computational deconvolution approaches work well in many specific... View Details
Keywords: Deconvolution; Methods; Open Innovation Competition; Genomics; Research; Innovation and Invention
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  • July 2023 (Revised July 2023)
  • Background Note

Generative AI Value Chain

By: Andy Wu and Matt Higgins
Generative AI refers to a type of artificial intelligence (AI) that can create new content (e.g., text, image, or audio) in response to a prompt from a user. ChatGPT, Bard, and Claude are examples of text generating AIs, and DALL-E, Midjourney, and Stable Diffusion are... View Details
Keywords: AI; Artificial Intelligence; Model; Hardware; Data Centers; AI and Machine Learning; Applications and Software; Analytics and Data Science; Value
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  • 15 Dec 2009
  • First Look

First Look: Dec. 15, 2009

  Working PapersThe Global Networks of Multinational Firms Authors:Laura Alfaro and Maggie Chen Abstract In this paper we characterize the topology of global multinational networks and examine the macro and... View Details
Keywords: Martha Lagace
  • 16 Nov 2016
  • Research & Ideas

Turning One Thousand Customers into One Million

and Uber can scale up quickly thanks to affordable technology and networked providers. Credit: AntonMatveev To overcome those challenges, the startups followed similar strategies, initially focusing more on the supply side than on the... View Details
Keywords: by Thales S. Teixeira and Michael Blanding; Retail; Transportation; Accommodations
  • 17 Aug 2010
  • First Look

First Look: August 17

explanations of workplace silence. We discuss implications of these results for theory and practice and suggest directions for future research. Paper not available   Working PapersPlatform Envelopment Authors:Thomas Eisenmann, Geoffrey Parker, and Marshall Van Alstyne... View Details
Keywords: Martha Lagace
  • 11 Feb 2020
  • Sharpening Your Skills

10 Rules Entrepreneurs Need to Know Before Adopting AI

for neural networks increase, as does accessibility to off-the-shelf APIs from big tech and academic institutions that help speed up innovation. Entrepreneurs have also learned the wisdom of targeting AI... View Details
Keywords: by Rocio Wu
  • 25 Aug 2003
  • Research & Ideas

Why IT Does Matter

but not nearly as dramatic as a computer produced in 2000, which runs 10 million times faster than a 1960s' computer. Carr's graph on information technology stands as a subject lesson for Darrell Huff's well-known book How to Lie with... View Details
Keywords: by F. Warren McFarlan & Richard L. Nolan
  • 01 Nov 2016
  • First Look

First Look - November 1, 2016

America Innovation Network By: Acemoglu, Daron, Ufuk Akcigit, and William R. Kerr Abstract— Technological progress builds upon itself, with the expansion of invention in one domain propelling future work in linked fields. Our analysis... View Details
Keywords: Sean Silverthorne
  • 02 Sep 2014
  • First Look

First Look: September 2

consumption. These findings imply that distinguishing appetite from consumption may improve predictions of future choice and illuminate neural components that support the process of decision making. Publisher's link:... View Details
Keywords: Sean Silverthorne
  • 14 May 2020
  • Research & Ideas

What Leaders Can Do to Fight the COVID Fog

that runners’ brains show more neural connections in areas associated with complex thought, such as attention, decision-making, and information processing. What you need: A minimum daily total of 30 minutes of an enjoyable physical... View Details
Keywords: by Boris Groysberg and Robin Abrahams
  • 28 Aug 2018
  • First Look

New Research and Ideas, August 28, 2018

although patenting in neural networks saw a strong burst of activity in the 1990s that has only recently been surpassed. In all technological fields, the number of patents per inventor has declined... View Details
Keywords: Dina Gerdeman
  • 23 Oct 2012
  • First Look

First Look: October 23

adaptive benefits of synchrony, including neural efficiency and the release of a reward signal that promotes future social interaction. In nature, neural synchrony yields behavioral synchrony. Humans use... View Details
Keywords: Sean Silverthorne
  • 16 Oct 2018
  • First Look

New Research and Ideas, October 16, 2018

Design Rules, Volume 2: How Technology Shapes Organizations: Chapter 5 Complementarity By: Baldwin, Carliss Y. Abstract—The purpose of this chapter is to relate the theory of task networks and technology set forth in previous chapters to... View Details
Keywords: Dina Gerdeman
  • 30 Oct 2007
  • First Look

First Look: October 30, 2007

in the multi-agent settings in which these decisions typically occur. In this paper, we develop a model that extends neural nets techniques to capture recognition processes in groups of decision-makers. We use the model to derive some... View Details
Keywords: Sean Silverthorne
  • 12 Feb 2007
  • Lessons from the Classroom

‘UpTick’ Brings Wall Street Pressure to Students

ideas," Coval says. Over the course of a simulation, students input their decisions on networked computers; once trading is halted, the program automatically generates a slideshow summary of individual and overall performance. The... View Details
Keywords: by Julia Hanna; Financial Services; Education
  • 27 Jul 2019
  • Op-Ed

Does Facebook's Business Model Threaten Our Elections?

business strategy, part of Facebook’s business model since at least 2010. That’s when Facebook opened up its Graph application programming interface (API) to advertisers, giving them access to user data including their social View Details
Keywords: by George Riedel
  • 02 Oct 2018
  • First Look

New Research and Ideas, October 2, 2018

and the supervised ML coding of facial images with a neural network algorithm. We employ these novel methods to study CEO oral communication, using videos and corresponding transcripts of emerging market CEO... View Details
Keywords: Dina Gerdeman

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