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  • September–October 2020
  • Article

The Past, Present, and (Near) Future of Gene Therapy and Gene Editing

By: Julia Pian, Amitabh Chandra and Ariel Dora Stern
Emerging gene therapy and gene-editing technologies will have a growing impact on patient lives and health-care delivery. We analyzed a decade of data on clinical trials and venture capital investments to understand the likely trajectory of genetically focused... View Details
Keywords: Gene Therapy; Gene Editing; Impact; Health Care and Treatment; Technological Innovation; Health Testing and Trials; Venture Capital; Change
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  • Web

Curriculum - MBA

confidentiality of clinical trial data, concerns about unjust research trials in low resource countries, and uncertainty about the value of genetic testing in drug development and study design will be... View Details
  • 10 Mar 2015
  • First Look

First Look: March 10

working paper: http://papers.ssrn.com/sol3/papers.cfm?abstract_id=2397317   Cases & Course Materials Harvard Business School Case 515-042 Simplot Plant Sciences: Designing a Better Potato Privately held Simplot has developed a new View Details
Keywords: Carmen Nobel
  • September 2020
  • Case

Minerva 2020: Clinical Trials

By: John R. Wells and Benjamin Weinstock
In March 2020, Dr. Cynthia Bamdad, founder and CEO of Minerva Biotechnologies Inc. (Minerva), was reviewing the first results of human clinical trials for the company’s novel CAR-T drug therapeutic, one of the first ever to target solid cancer tumors. The results... View Details
Keywords: Biotechnology; Strategic Decision Making; Entrepreneurship; Health Testing and Trials; Decision Choices and Conditions; Strategy
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  • 01 Sep 2023
  • News

Money Does Grow on (Family) Trees

first genetic tests focused on ancestry were coming on the market. Though they were expensive and of limited utility, Cusenza saw the science rapidly improving, and he recognized opportunity not just in the... View Details
Keywords: April White; Illustrations by Fabio Consoli; News, Library, Internet, and Other Services; Information
  • 2008
  • Chapter

The Evidence Does Not Speak for Itself: Expert Witnesses and the Organization of DNA-Typing Companies

By: Arthur A. Daemmrich
During the past 15 years, new biotechnology companies have promoted DNA typing as a sophisticated criminal and paternity identification technique. Private testing laboratories produce results that link individuals with crime scenes and fathers to their children.... View Details
Keywords: Governing Rules, Regulations, and Reforms; Courts and Trials; Organizational Structure; Practice; Genetics; Science-Based Business; Trust; Commercialization; Vertical Integration
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  • 01 Dec 2023
  • News

Wide Horizon

There were three critical events that led John Rodakis (MBA 1997) to form the nonprofit N of One in 2014 and ultimately dedicate his life to surfacing breakthrough autism research. The first occurred on Thanksgiving of 2012. He had driven about four hours with his wife... View Details
Keywords: Dan Morrell; Photos by Sarah Wilson
  • 20 Jul 2011
  • Research & Ideas

Five Discovery Skills that Distinguish Great Innovators

that distinguish innovative entrepreneurs and executives from run-of-the-mill managers. What Makes Innovators Different? So what makes innovators different from the rest of us? Most of us believe this question has been answered. It's a View Details
Keywords: by Jeff Dyer, Hal Gergersen & Clayton M. Christensen
  • 01 Mar 2024
  • News

On the Radar

Illustration by Brian Stauffer Illustration by Brian Stauffer Our planet is teeming with trillions of viruses and bacteria, most of which are innocuous or even helpful, but some pose a significant risk to public health, animals, and crops. In recent decades,... View Details
Keywords: Janine White; Justice, Public Order, and Safety Activities; Government
  • 21 Jan 2014
  • First Look

First Look: January 21

out its Genetics Diagnostic Lab into a fully commercial entity. Claritas offered over 100 genomic tests to detect a range of conditions, including autism and intellectual disabilities, and was developing new... View Details
Keywords: Sean Silverthorne
  • 13 Jan 2009
  • First Look

First Look: January 13, 2009

Should this gene detection firm enter the business of providing tests for the detection of genetic diseases? If so, how should it prioritize the tests it could develop?... View Details
Keywords: Martha Lagace
  • Web

Topics - HBS Working Knowledge

(7) Gender (129) Genetics (1) Geographic Location (11) Geographic Scope (10) Geography (30) Geopolitical Units (7) Giving and Philanthropy (26) Global Range (8) Global Strategy (9) Globalization (270) Globalized Economies and Regions (15)... View Details
  • February 2024
  • Article

Are Many Sex/Gender Differences Really Power Differences?

By: Adam D. Galinsky, Aurora Turek, Grusha Agarwal, Eric M. Anicich, Derek D. Rucker, Hannah Riley Bowles, Nira Liberman, Chloe Levin and Joe C Magee
This research addresses the long-standing debate about the determinants of sex/gender differences. Evolutionary theorists trace many sex/gender differences back to natural selection and sex-specific adaptations. Sociocultural and biosocial theorists, in contrast,... View Details
Keywords: Gender; Genetics; Power and Influence; Social Issues
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  • Web

Winners & Runners-Up | New Venture Competition

Winners & Runners-Up 2024 Winners Play Video duration: 1:31 2024 New Venture Competition Winner, Business Track: Crop Diagnostix Crop Diagnostix is redefining precision agriculture through AI-powered, genetic insights. Team: Brandon Chi,... View Details
  • Web

Rare Disease Day – Small Numbers, Big Challenges… and Big Opportunities - Blog: Health Supplement

Thanks to her relentless efforts, we are part of the fortunate few that have been properly genetically tested and diagnosed. While rare, HHT is the second most common inherited bleeding disorder, and yet... View Details
  • 01 Dec 2019
  • News

Bridging the Gap

boutique-filled neighborhood and ending in another. Over at Niedlov’s Breadworks, there are iced lattes and avocado toast—the litmus test for millennial happiness. And humming through it all is a citywide 10-gigabit network, courtesy of... View Details
Keywords: Julia Hanna; illustration by Josh Cochran; photographed by Melissa Golden; cross sector collaboration; local government; nonprofits; education; leadership; Administration of Economic Programs; Government
  • 21 Feb 2005
  • Op-Ed

Is Business Management a Profession?

since the Middle Ages by the rise and ongoing progress of modern science. The development of the germ theory of disease in the nineteenth century, for example, and of the science of genetics in the twentieth, have gone into the formation... View Details
Keywords: by Rakesh Khurana, Nitin Nohria & Daniel Penrice
  • 08 Sep 2008
  • HBS Case

The Value of Environmental Activists

There are many methods, most financial, to measure the success of companies in meeting goals. But the question becomes a lot harder at Harvard Business School when MBAs are challenged to measure the efforts of environmental organizations like Greenpeace and the World... View Details
Keywords: by Sarah Jane Gilbert; Energy; Utilities
  • 01 Jun 2018
  • News

Floor It

The sci-fi future for cancer treatment has become a reality, with breakthrough therapies that can use a cancer patient’s genetic information to create personalized treatments or employ the body’s immune response to treat disease. But for... View Details
Keywords: Julia Hanna; illustration by Mengxin Li
  • 29 May 2001
  • Research & Ideas

Genomics: Can We Start Making Money Now?

drugs, and will they be less expensive?' My answer is, 'I don't know, and probably not.' Lechleiter was one of several panelists to discuss, "Breaking the Genetic Code: The Business of Life Science in the 21st Century" at the... View Details
Keywords: by Sean Silverthorne