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Publications

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  • All HBS Web  (116)
    • Faculty Publications  (35)

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    • All HBS Web  (116)
      • Faculty Publications  (35)

      Drug DiscoveryRemove Drug Discovery →

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      • 2004
      • Article

      Do Firms Change Capabilities by Hiring New People? A Study of the Adoption of Science-based Drug Discovery

      By: Rebecca M. Henderson, Nicola Lacetera and Iain Cockburn
      Keywords: Selection and Staffing; Change; Science; Health; Information
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      Henderson, Rebecca M., Nicola Lacetera, and Iain Cockburn. "Do Firms Change Capabilities by Hiring New People? A Study of the Adoption of Science-based Drug Discovery." Advances in Strategic Management 21 (2004).
      • July 2002
      • Article

      Asset Accumulation, Interdependence and Technological Change: Evidence from Pharmaceutical Drug Discovery

      By: Stefan Thomke and Walter Kuemmerle
      Keywords: Assets; Information Technology; Change; Health
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      Thomke, Stefan, and Walter Kuemmerle. "Asset Accumulation, Interdependence and Technological Change: Evidence from Pharmaceutical Drug Discovery." Strategic Management Journal 23, no. 7 (July 2002): 619–635.
      • April 2002
      • Case

      In vivo to in vitro to in silico: Coping with Tidal Waves of Data at Biogen

      By: Juan Enriquez-Cabot, Gary P. Pisano and Gaye Bok
      Biogen is a successful biotech company facing a critical juncture. CEO John Mullen ponders how technological changes introduced into the research function will shape larger corporate decisions. This world in which biotechnology companies operated had changed... View Details
      Keywords: Change; Decisions; Product Development; Research and Development; Expansion; Technology; Biotechnology Industry
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      Enriquez-Cabot, Juan, Gary P. Pisano, and Gaye Bok. "In vivo to in vitro to in silico: Coping with Tidal Waves of Data at Biogen." Harvard Business School Case 602-122, April 2002.
      • 2001
      • Working Paper

      Asset Accumulation, Interdependence and Technological Change: Evidence from Pharmaceutical Drug Discovery

      By: Stefan Thomke and Walter Kuemmerle
      Citation
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      Thomke, Stefan, and Walter Kuemmerle. "Asset Accumulation, Interdependence and Technological Change: Evidence from Pharmaceutical Drug Discovery." Harvard Business School Working Paper, No. 00-086, July 2001.
      • 2000
      • Chapter

      Measuring Competence? Exploring Firm Effects in Drug Discovery

      By: Rebecca M. Henderson and Iain Cockburn
      Keywords: Competency and Skills; Measurement and Metrics; Research and Development; Innovation and Invention; Pharmaceutical Industry
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      Henderson, Rebecca M., and Iain Cockburn. "Measuring Competence? Exploring Firm Effects in Drug Discovery." Chap. 6 in The Nature and Dynamics of Organizational Capabilities, edited by Giovanni Dosi, Richard Nelson, and Sidney Winter. New York: Oxford University Press, 2000.
      • Article

      Strategic Assets, Interdependence and Technological Change: An Empirical Investigation of Complementarity in Pharmaceutical Drug Discovery

      By: S. Thomke and W. Kuemmerle
      Keywords: Strategy; Assets; Information Technology; Change; Information; Health; Pharmaceutical Industry
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      Thomke, S., and W. Kuemmerle. "Strategic Assets, Interdependence and Technological Change: An Empirical Investigation of Complementarity in Pharmaceutical Drug Discovery." Academy of Management Proceedings and Membership Directory (2000).
      • 1999
      • Chapter

      The Economics of Drug Discovery

      By: Rebecca M. Henderson and Iain Cockburn
      Keywords: Economics; Innovation and Invention; Research and Development; Pharmaceutical Industry
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      Henderson, Rebecca M., and Iain Cockburn. "The Economics of Drug Discovery." Chap. 5 in Pharmaceutical Innovation, edited by Ralph Landau, Basil Achilladelis, and Alexander Scriabine, 308–331. Philadelphia: Chemical Heritage Press, 1999.
      • Article

      Absorptive Capacity, Coauthoring Behavior, and the Organization of Research in Drug Discovery

      By: Rebecca M. Henderson and Iain Cockburn
      Keywords: Behavior; Research and Development; Organizations; Health
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      Henderson, Rebecca M., and Iain Cockburn. "Absorptive Capacity, Coauthoring Behavior, and the Organization of Research in Drug Discovery." Journal of Industrial Economics 46, no. 2 (June 1998): 157–182.
      • October 1997 (Revised September 2003)
      • Case

      Eli Lilly and Company: Drug Development Strategy (A)

      By: Stefan H. Thomke, Ashok Nimgade and Paul Pospisil
      Describes how Eli Lilly and Co. tries to accelerate its new drug development process with the aid of "combinatorial chemistry"--a rapidly emerging and revolutionary approach to preclinical drug discovery. The product manager of a potential blockbuster migraine drug... View Details
      Keywords: Chemicals; Finance; Innovation and Invention; Time Management; Markets; Product Development; Organizations; Business Processes; Problems and Challenges; Business and Stakeholder Relations; Competition; Pharmaceutical Industry
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      Thomke, Stefan H., Ashok Nimgade, and Paul Pospisil. "Eli Lilly and Company: Drug Development Strategy (A)." Harvard Business School Case 698-010, October 1997. (Revised September 2003.)
      • 1996
      • Chapter

      The Determinants of Research Productivity in Ethical Drug Discovery

      By: Rebecca M. Henderson and Ian Cockburn
      Keywords: Ethics; Health Testing and Trials; Research and Development; Performance Productivity; Pharmaceutical Industry
      Citation
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      Henderson, Rebecca M., and Ian Cockburn. "The Determinants of Research Productivity in Ethical Drug Discovery." In Competitive Strategies in the Pharmaceutical Industry, edited by Robert B. Helms. Washington, D.C.: AEI Press, 1996.
      • spring 1996
      • Article

      Scale, Scope and Spillovers: The Determinants of Research Productifity in Drug Discovery

      By: Rebecca M. Henderson and Ian Cockburn
      Keywords: Research; Product; Health
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      Henderson, Rebecca M., and Ian Cockburn. "Scale, Scope and Spillovers: The Determinants of Research Productifity in Drug Discovery." RAND Journal of Economics 27, no. 1 (spring 1996): 32–59.
      • fall 1994
      • Article

      Racing to Invest? The Dynamics of Competition in Ethical Drug Discovery

      By: Rebecca M. Henderson and Ian Cockburn
      Keywords: Investment; Competition; Ethics; Health
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      Henderson, Rebecca M., and Ian Cockburn. "Racing to Invest? The Dynamics of Competition in Ethical Drug Discovery." Journal of Economics & Management Strategy 3, no. 3 (fall 1994): 481–519.
      • Article

      Measuring Competence? Exploring Firm Effects in Drug Discovery

      By: Rebecca M. Henderson and Ian Cockburn
      Keywords: Measurement and Metrics; Competency and Skills; Health
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      Henderson, Rebecca M., and Ian Cockburn. "Measuring Competence? Exploring Firm Effects in Drug Discovery." Strategic Management Journal 15 (Winter 1994): 63–84. (Winner of Dan and Mary Lou Schendel Best Paper Prize To honor substantial work published in the Strategic Management Journal presented by Strategic Management Society​.)
      • 1994
      • Article

      The Evolution of Integrative Capability: Innovation in Cardiovascular Drug Discovery

      By: Rebecca M. Henderson
      Keywords: Innovation and Invention; Health; Integration
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      Henderson, Rebecca M. "The Evolution of Integrative Capability: Innovation in Cardiovascular Drug Discovery." Industrial and Corporate Change 3, no. 3 (1994): 607–630.
      • Research Summary

      Overview

      By: Joshua Lev Krieger
      In examining the competitive dynamics of R&D strategy, Josh has become particularly interested in how the introduction of new knowledge generated by rivals impacts the direction of R&D efforts. Understanding how new information alters project portfolio decisions is... View Details
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