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    • All HBS Web  (354)
      • Faculty Publications  (59)

      Breakthrough InnovationRemove Breakthrough Innovation →

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      • 2024
      • Working Paper

      Gastrointestinal Endoscopy--Without Cutting In: Case Histories of Transformational Advances

      By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
      This case history describes how endoscopy transformed the diagnosis of ulcers, cancerous polyps, and other alimentary canal diseases and enabled “minimally invasive” surgeries to treat such diseases. Specifically, we chronicle how: 1) flexible glass fiber endoscopes... View Details
      Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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      Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Gastrointestinal Endoscopy--Without Cutting In: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-005, July 2019. (Revised May 2024.)
      • March 2018 (Revised September 2023)
      • Case

      X: The Foghorn Decision

      By: Robert S. Huckman, Karim R. Lakhani and Kyle R. Myers
      In February 2016, Kathy Hannun—a project leader at X, Alphabet Inc.'s so-called "moonshot factory"—had to prepare a recommendation for the senior leadership of X regarding the future of Foghorn, a project she was leading to develop a carbon-neutral process for... View Details
      Keywords: Innovation; R&D Project Management; Radical Innovation; Clean Technology; Innovation and Management; Technological Innovation; Energy; Research and Development; Projects; Management; Decision Choices and Conditions; Technology Industry; Energy Industry; Green Technology Industry; California
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      Huckman, Robert S., Karim R. Lakhani, and Kyle R. Myers. "X: The Foghorn Decision." Harvard Business School Case 618-060, March 2018. (Revised September 2023.)
      • January 2018
      • Case

      Flying into the Future: HondaJet

      By: Gary P. Pisano and Jesse Shulman
      This cases examine Honda’s diversification into the light jet market. In 1985, Honda initiated a secret program to develop a small jet. Over the years, the program had many ups and downs (it was almost canceled several times). Then, a breakthrough in the configuration... View Details
      Keywords: Diversification; Technological Innovation; Growth and Development Strategy; Innovation and Management; Air Transportation Industry
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      Pisano, Gary P., and Jesse Shulman. "Flying into the Future: HondaJet." Harvard Business School Case 618-012, January 2018.
      • Article

      The Board's New Innovation Imperative: Directors Need to Rethink Their Roles and Their Attitude to Risk

      By: Linda A. Hill and George Davis
      As firms scramble for competitive advantage, boards—once the cautious voices urging management to mitigate risk—are now calling for breakthrough innovation. Indeed, avoiding risk is now seen as the riskiest proposition of all. In speaking with CEOs and board members... View Details
      Keywords: Governing and Advisory Boards; Innovation Leadership; Risk and Uncertainty; Corporate Governance
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      Hill, Linda A., and George Davis. "The Board's New Innovation Imperative: Directors Need to Rethink Their Roles and Their Attitude to Risk." Harvard Business Review 95, no. 6 (November–December 2017): 102–109.
      • May 2017 (Revised October 2017)
      • Case

      Hyperloop Transportation Technologies: Building Breakthrough Innovations in Crowd-Powered Ecosystems

      By: Lynda M. Applegate, Terri L. Griffith and Ann Majchrzak
      Dirk Ahlborn, co-founder and CEO of Hyperloop Transportation Technologies, Inc. (HTT) looks back at the evolving organizational design and community that allows HTT to be crowd-powered. Since the founding in 2013, HTT has dealt with building an organization with less... View Details
      Keywords: Collaboration; Crowdsourcing; Entrepreneurial Finance; Innovation; Organizational Design; Startups; Business Startups; Collaborative Innovation and Invention; Entrepreneurship; Finance; Product Development
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      Applegate, Lynda M., Terri L. Griffith, and Ann Majchrzak. "Hyperloop Transportation Technologies: Building Breakthrough Innovations in Crowd-Powered Ecosystems." Harvard Business School Case 817-134, May 2017. (Revised October 2017.)
      • 2017
      • Chapter

      Entrepreneurship in Larger Companies

      By: William R. Kerr
      Entrepreneurship in large and established companies is vital for their long-term success. Incumbent firms face many challenges ranging from global competition to digitization. In times past, being caught flat-footed might have set a company back several years, but it... View Details
      Keywords: Corporate Entrepreneurship
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      Kerr, William R. "Entrepreneurship in Larger Companies." Chap. 27 in The Entrepreneur's Roadmap: From Concept to IPO, edited by Tim Dempsey and Bonnie Hyun, 161–164. Chicago, IL: Caxton Business & Legal, Inc., 2017.
      • December 2016
      • Background Note

      Reaching Beyond Your Organization: Empowering Innovation

      By: William R. Kerr
      Forward-thinking established companies utilize new routes for external innovation with start-ups and crowds. The reading reviews strategic partnerships, strategic investments, strategic acquisitions, and crowd-based collaborations. Case examples include Google, SK... View Details
      Keywords: Innovation; Corporate Innovation; Collaboration; Partnerships; Innovation and Invention; Collaborative Innovation and Invention; Innovation Strategy
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      Kerr, William R. "Reaching Beyond Your Organization: Empowering Innovation." Harvard Business School Background Note 817-044, December 2016.
      • November 2016 (Revised April 2018)
      • Case

      reMarkable: e-Writing the Future

      By: Elie Ofek and Curtis Hsu
      Magnus Wanberg is the creator of reMarkable, a breakthrough e-writer device set apart from similar products on the market by having solved the frustrating “slow ink” problem typically experienced on pen-based electronic devices, thus providing a “pen and paper” like... View Details
      Keywords: Entrepreneurial Marketing; Innovation Management; Go To Market Strategy; Marketing Plan; Target Market; Digital Devices; Consumer Electronics; Forecasting; Information Technology; Marketing Strategy; Innovation and Management; Marketing Channels; Entrepreneurship; Forecasting and Prediction; Product Marketing; Product Development; Electronics Industry
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      Ofek, Elie, and Curtis Hsu. "reMarkable: e-Writing the Future." Harvard Business School Case 517-018, November 2016. (Revised April 2018.)
      • May–June 2015
      • Other Article

      The Challenges of Ambidextrous Leadership: An Interview with Michael Tushman

      By: Michael Tushman and Jim Euchner
      Michael Tushman talks with Jim Euchner about the challenges of managing breakthrough innovation in established companies. View Details
      Keywords: Innovation and Management
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      Tushman, Michael, and Jim Euchner. "The Challenges of Ambidextrous Leadership: An Interview with Michael Tushman." Research-Technology Management 58, no. 3 (May–June 2015): 16–20.
      • July 2013
      • Case

      Novozymes: Establishing the Cellulosic Ethanol Value Chain

      By: Willy Shih and Sen Chai

      As the world's largest producer of industrial enzymes, Novozymes had invested heavily for many years to bio-engineer enzymes that could break down cellulose into fermentable sugar. In 2010, the company had launched what it thought would become a breakthrough product... View Details

      Keywords: System Complexity; Industrial Enzymes; Ethanol; Collulosic Ethanol; Fermentation; Genomics; Genetic Engineering; Value Chain; Assembling Value Chain; Energy Sources; Renewable Energy; Collaborative Innovation and Invention; Innovation and Management; Innovation Strategy; Technological Innovation; Management; Growth and Development Strategy; Industry Growth; Production; Research; Research and Development; Science; Genetics; Natural Environment; Environmental Sustainability; Science-Based Business; Business Strategy; Commercialization; Vertical Integration; Agriculture and Agribusiness Industry; Biotechnology Industry; Energy Industry; Denmark; United States
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      Shih, Willy, and Sen Chai. "Novozymes: Establishing the Cellulosic Ethanol Value Chain." Harvard Business School Case 614-001, July 2013.
      • Article

      Experiments in Open Innovation at Harvard Medical School

      By: Eva C. Guinan, Kevin J. Boudreau and Karim R. Lakhani
      Harvard Medical School seems an unlikely organization to open up its innovation process. By most measures, the more than 20,000 faculty, research staff and graduate students affiliated with Harvard Medical School are already world class and at the top of the medical... View Details
      Keywords: Health Disorders; Collaborative Innovation and Invention; Boston
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      Guinan, Eva C., Kevin J. Boudreau, and Karim R. Lakhani. "Experiments in Open Innovation at Harvard Medical School." Art. 3. MIT Sloan Management Review 54, no. 3 (Spring 2013): 45–52.
      • April 2013
      • Article

      In Search of a Second Act: Riding the Popularity of a Great First Product Is Easy; Finding the Next One Is Hard

      By: Elie Ofek and Jill Avery
      The article presents a fictional case study on new product development and improvement after the successful launch of a first breakthrough product. Topics include business planning for brand name products, finance and investment for the development of educational toys,... View Details
      Keywords: Innovation; Growth Strategy; Consumer Marketing; Marketing; Brand Management; Market Research; New Product Development; Marketing Management; Technology Commercialization; Technology; Brands and Branding; Marketing Strategy; Product Marketing; Consumer Products Industry; Electronics Industry; Technology Industry; North and Central America; United States
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      Ofek, Elie, and Jill Avery. "In Search of a Second Act: Riding the Popularity of a Great First Product Is Easy; Finding the Next One Is Hard." Harvard Business Review 91, no. 4 (April 2013): 133–137.
      • June 2012
      • Supplement

      Foro Energy (B)

      By: Joseph B. Lassiter, William A. Sahlman and James McQuade
      Foro Energy developed proprietary and patent-pending fiber-laser technologies that could disrupt existing processes and services for the exploration and production of oil and natural gas. These breakthrough laser technologies were protected by a strong intellectual... View Details
      Keywords: Disruptive Technologies; Innovation & Entrepreneurship; Development Stage Enterprises; Entrepreneurial Management; Entrepreneurs; Petroleum; Natural Gas; High Technology; Energy; Entrepreneurship; Disruptive Innovation; Technological Innovation; Intellectual Property; Energy Industry
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      Lassiter, Joseph B., William A. Sahlman, and James McQuade. "Foro Energy (B)." Harvard Business School Supplement 812-163, June 2012.
      • March 2012 (Revised December 2012)
      • Case

      Foro Energy (A)

      By: Joseph B. Lassiter III, William A. Sahlman and James McQuade
      Foro Energy developed proprietary and patent-pending fiber-laser technologies that could disrupt existing processes and services for the exploration and production of oil and natural gas. These breakthrough laser technologies were protected by a strong intellectual... View Details
      Keywords: Disruptive Innovation; Growth and Development Strategy; Entrepreneurship; United States
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      Lassiter, Joseph B., III, William A. Sahlman, and James McQuade. "Foro Energy (A)." Harvard Business School Case 812-136, March 2012. (Revised December 2012.)
      • 2010
      • Chapter

      Breakthrough Inventions and the Growth of Innovation Clusters

      By: William R. Kerr
      This report provides a comprehensive look at the role of innovation in promoting economic and social development. It examines the impact of innovation on the economic growth of developing countries and the future role of technological innovation in international... View Details
      Keywords: Technological Innovation; Developing Countries and Economies; Society; Growth and Development; Climate Change; Social Issues; Industry Clusters; Business and Government Relations
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      Kerr, William R. "Breakthrough Inventions and the Growth of Innovation Clusters." In The Innovation for Development Report 2010-2011, edited by Augusto Lopez-Claros, 103–107. Hampshire, England: Palgrave Macmillan, 2010.
      • May 2010
      • Column

      Block-by-Blockbuster Innovation

      By: Rosabeth Moss Kanter
      Executives often find themselves debating the merits of incremental innovations versus game-changers, but that's a false dichotomy, says HBR columnist Rosabeth Moss Kanter. Even if a company is lucky enough to come up with the next Kindle, Swiffer, or smartphone,... View Details
      Keywords: Innovation and Management; Resource Allocation; Product; Business Processes; Risk and Uncertainty
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      Kanter, Rosabeth Moss. "Block-by-Blockbuster Innovation." Harvard Business Review 88, no. 5 (May 2010): 38.
      • January 2010
      • Article

      Breakthrough Inventions and Migrating Clusters of Innovation

      By: William R. Kerr
      We investigate the speed at which clusters of invention for a technology migrate spatially following breakthrough inventions. We identify breakthrough inventions as the top one percent of U.S. inventions for a technology during 1975-1984 in terms of subsequent... View Details
      Keywords: History; Technological Innovation; Patents; Labor; Immigration; United States
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      Kerr, William R. "Breakthrough Inventions and Migrating Clusters of Innovation." Journal of Urban Economics 67, no. 1 (January 2010): 46–60.
      • Article

      What Really Motivates Workers

      By: Teresa M. Amabile and Steve J. Kramer
      This essay appears in "The HBR List: Breakthrough Ideas for 2010," which is compiled by this journal in collaboration with the World Economic Forum. The ten problems and the innovative solutions are discussed in each essay. This particular essay describes research... View Details
      Keywords: Problems and Challenges; Innovation and Invention; Research; Performance Improvement; Managerial Roles; Motivation and Incentives; Creativity
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      Amabile, Teresa M., and Steve J. Kramer. "What Really Motivates Workers." Harvard Business Review 88, nos. 1/2 (January–February 2010): 44–45. (#1 in Breakthrough Ideas for 2010.)
      • 2009
      • Working Paper

      Breakthrough Inventions and Migrating Clusters of Innovation

      By: William R. Kerr
      Citation
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      Kerr, William R. "Breakthrough Inventions and Migrating Clusters of Innovation." NBER Working Paper Series, No. 15443, October 2009.
      • 2009
      • Working Paper

      Breakthrough Inventions and Migrating Clusters of Innovation

      By: William R. Kerr
      We investigate the speed at which clusters of invention for a technology migrate spatially following breakthrough inventions. We identify breakthrough inventions as the top one percent of US inventions for a technology during 1975-1984 in terms of subsequent citations.... View Details
      Keywords: Geographic Location; Immigration; Disruptive Innovation; Technological Innovation; Patents; Industry Clusters; United States
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      Kerr, William R. "Breakthrough Inventions and Migrating Clusters of Innovation." Harvard Business School Working Paper, No. 10-020, September 2009.
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