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21 Nov 2008
Working Paper Summaries

Applicant and Examiner Citations in U.S. Patents: An Overview and Analysis

Keywords: by Juan Alcacer

Research Summary

Moral Reasoning & Experimental Political Philosophy

In this work, we demonstrate a new and morally significant effect on judgment and decision-making. This research is inspired by the work of John Rawls, widely regarded as the most important political philosopher of the 20th Century. Here we apply the central... View Details

Keywords: Ethics; Fairness; Distributive Justice

September 15, 2021
Article

Improving Deconvolution Methods in Biology Through Open Innovation Competitions: An Application to the Connectivity Map

By: Andrea Blasco, Ted Natoli, Michael G. Endres, Rinat A. Sergeev, Steven Randazzo, Jin Hyun Paik, N.J. Maximilian Macaluso, Rajiv Narayan, Xiaodong Lu, David Peck, Karim R. Lakhani and Aravind Subramanian

A recurring problem in biomedical research is how to isolate signals of distinct populations (cell types, tissues, and genes) from composite measures obtained by a single analyte or sensor. Existing computational deconvolution approaches work well in many specific... View Details

Keywords: Deconvolution; Methods; Open Innovation Competition; Genomics; Research; Innovation and Invention

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25 Aug 2015
First Look

First Look Tuesday

large body of research and presenting a new framework that attempts to integrate these new findings, our hope is to motivate new research about how to support more moral workplace behavior that starts from... View Details

March 2008 (Revised June 2008)
Case

The Broad Institute: Applying the Power of Genomics to Medicine

By: Vicki L. Sato and Rachel Gordon

In June 2003, Harvard University and MIT announced an unprecedented partnership to create a biomedical institute, The Broad Institute. The culture of the Broad centered on science, and those involved considered it to be at the edge of the scientific frontier. In just... View Details

Keywords: Education; Health Care and Treatment; Innovation Leadership; Growth and Development Strategy; Organizational Culture; Partners and Partnerships; Research and Development; Genetics

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2001
Chapter

Publicly Funded Science and the Productivity of the Pharmaceutical Industry

By: Rebecca Henderson and Ian Cockburn

U.S. taxpayers funded $14.8 billion of health related research last year, four times the amount that was spent in 1970 in real terms. In this paper we evaluate the impact of these huge expenditures on the technological performance of the pharmaceutical industry. While... View Details

Keywords: Public Sector; Science-Based Business; Research and Development; Sovereign Finance; Pharmaceutical Industry

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22 Feb 2022
Research & Ideas

Lack of Female Scientists Means Fewer Medical Treatments for Women

Women Focus More on Women’s Health, but Few Women Get to Invent. To better understand the potential volume of good ideas that never became inventions, the research team crunched biomedical patent data... View Details

Keywords: by Kristen Senz

22 Apr 2009
Working Paper Summaries

Where is the Pharmacy to the World? International Regulatory Variation and Pharmaceutical Industry Location

Keywords: by Arthur Daemmrich; Pharmaceutical

28 Aug 2023
Research & Ideas

The Clock Is Ticking: 3 Ways to Manage Your Time Better

biomedical research institute. We measured employees’ daily work locations using building-badge swipe data, as well as various work and work-life outcomes via biweekly surveys. We found that each employee’s... View Details

Keywords: by Kristen Senz

2009
Working Paper

Social Influence Given (Partially) Deliberate Matching: Career Imprints in the Creation of Academic Entrepreneurs

By: Pierre Azoulay, Christopher C. Liu and Toby E. Stuart

Actors often match with associates on a small set of dimensions that matter most for the particular relationship at hand. In so doing, they are exposed to unanticipated social influences because counterparts have more interests, attitudes, and preferences than would-be... View Details

Keywords: Entrepreneurship; Patents; Marketplace Matching; Mathematical Methods; Science-Based Business; Power and Influence; Social and Collaborative Networks; Biotechnology Industry

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26 Jul 2024
Research & Ideas

Why Great Ideas Get Stuck in Universities

commercial hindrance. A recent study of more than 500 biomedical startups suggests that ventures rooted in the core research of their founders have a more challenging time reaching key measures of success,... View Details

Keywords: by Ben Rand; Biotechnology; Health

13 Mar 2018
First Look

March 13, 2018

historians in recent years, academic research on business groups has, to date, remained within the boundary of emerging markets. The major aim of this volume is to explore the long-term evolution of different varieties of large... View Details

Keywords: Sean Silverthorne

26 Mar 2012
Research & Ideas

What Neuroscience Tells Us About Consumer Desire

for behavior, and draws on concepts and techniques from neuroscience to inform her research in marketing. For corporations, on the other hand, the science is a means to an end goal of selling more stuff. But the tools, once restricted to... View Details

Keywords: by Carmen Nobel; Consumer Products

28 Feb 2012
First Look

First Look: Feb. 28

Biomedical Research: Building a Sustainable, Globally Integrated Research Enterprise Vicki Sato, Christoph Jaeker, and Pooja Mehta SolankiHarvard Business School Case 612-048 As the head of the Novartis... View Details

Keywords: Sean Silverthorne

12 Mar 2013
First Look

First Look: March 12

A. Arnaout Publication:Nature Biotechnology Abstract Advances in biotechnology have fueled the generation of unprecedented quantities of data across the life sciences. However, finding analysts who can address such "big data" problems effectively has become a... View Details

Keywords: Sean Silverthorne

05 Sep 2012
First Look

First Look: September 5

hospitals and research centers to understand how colocation impacts the likelihood of scientific collaboration. We introduce exogenous colocation and face-to-face interactions for a random subset of View Details

Keywords: Sean Silverthorne

23 Feb 2016
First Look

February 23, 2016

filing date rather than at patent grant—on the timing of licensing deals in the biomedical industry. We find that post-AIPA U.S. patent applications are significantly more likely to be licensed before patent grant and shortly after... View Details

Keywords: Sean Silverthorne

17 Sep 2013
First Look

First Look: September 17

Paul Healy, George Serafeim, and Devin Shanthikumar Abstract—Prior research on equity analysts focuses almost exclusively on those employed by sell-side investment banks and brokerage houses. Yet investment firms undertake their own... View Details

Keywords: Sean Silverthorne

20 May 2013
Op-Ed

Making America an Industrial Powerhouse Again

industries. Research funded by the Defense Advanced Research Projects Agency (DARPA) sowed the seeds for the internet and advanced computer graphics. And massive investments by the National Institutes of... View Details

Keywords: by Gary Pisano; Manufacturing

18 Apr 2019
Research & Ideas

Open Innovation Contestants Build AI-Based Cancer Tool

Science at Harvard (LISH) has a long history of working together with Harvard Catalyst at Harvard Medical School to identify interesting innovation and process problems in translational biomedical areas. We have conducted many View Details

Keywords: by Martha Lagace; Health; Medical Devices & Supplies