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  • All HBS Web  (101)
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    • News  (29)
    • Research  (46)
    • Events  (4)
    • Multimedia  (1)
  • Faculty Publications  (24)
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  • November 2019
  • Case

The Genesis Lab at Novartis

By: Amy C. Edmondson, Ranjay Gulati, Patrick J. Healy and Kerry Herman
Novartis' Genesis Labs program, launched in 2016 as part of Novartis Institutes for Biomedical Research (NIBR), hosted pitch competitions where teams of NIBR scientists proposed ideas to explore that aimed to revolutionize drug discovery. The goal was to break down... View Details
Keywords: Drug Discovery; Health Care and Treatment; Research and Development; Innovation and Invention; Programs; Management
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Edmondson, Amy C., Ranjay Gulati, Patrick J. Healy, and Kerry Herman. "The Genesis Lab at Novartis." Harvard Business School Case 620-007, November 2019.
  • Research Summary

Moral Reasoning & Experimental Political Philosophy

In this work, we demonstrate a new and morally significant effect on judgment and decision-making. This research is inspired by the work of John Rawls, widely regarded as the most important political philosopher of the 20th Century. Here we apply the central... View Details
Keywords: Ethics; Fairness; Distributive Justice
  • September 15, 2021
  • Article

Improving Deconvolution Methods in Biology Through Open Innovation Competitions: An Application to the Connectivity Map

By: Andrea Blasco, Ted Natoli, Michael G. Endres, Rinat A. Sergeev, Steven Randazzo, Jin Hyun Paik, N.J. Maximilian Macaluso, Rajiv Narayan, Xiaodong Lu, David Peck, Karim R. Lakhani and Aravind Subramanian
A recurring problem in biomedical research is how to isolate signals of distinct populations (cell types, tissues, and genes) from composite measures obtained by a single analyte or sensor. Existing computational deconvolution approaches work well in many specific... View Details
Keywords: Deconvolution; Methods; Open Innovation Competition; Genomics; Research; Innovation and Invention
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Blasco, Andrea, Ted Natoli, Michael G. Endres, Rinat A. Sergeev, Steven Randazzo, Jin Hyun Paik, N.J. Maximilian Macaluso, Rajiv Narayan, Xiaodong Lu, David Peck, Karim R. Lakhani, and Aravind Subramanian. "Improving Deconvolution Methods in Biology Through Open Innovation Competitions: An Application to the Connectivity Map." Bioinformatics 37, no. 18 (September 15, 2021).
  • 25 Aug 2015
  • First Look

First Look Tuesday

large body of research and presenting a new framework that attempts to integrate these new findings, our hope is to motivate new research about how to support more moral workplace behavior that starts from... View Details
  • March 2008 (Revised June 2008)
  • Case

The Broad Institute: Applying the Power of Genomics to Medicine

By: Vicki L. Sato and Rachel Gordon
In June 2003, Harvard University and MIT announced an unprecedented partnership to create a biomedical institute, The Broad Institute. The culture of the Broad centered on science, and those involved considered it to be at the edge of the scientific frontier. In just... View Details
Keywords: Education; Health Care and Treatment; Innovation Leadership; Growth and Development Strategy; Organizational Culture; Partners and Partnerships; Research and Development; Genetics
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Sato, Vicki L., and Rachel Gordon. "The Broad Institute: Applying the Power of Genomics to Medicine." Harvard Business School Case 608-114, March 2008. (Revised June 2008.)
  • 22 Feb 2022
  • Research & Ideas

Lack of Female Scientists Means Fewer Medical Treatments for Women

Women Focus More on Women’s Health, but Few Women Get to Invent. To better understand the potential volume of good ideas that never became inventions, the research team crunched biomedical patent data... View Details
Keywords: by Kristen Senz
  • 22 Apr 2009
  • Working Paper Summaries

Where is the Pharmacy to the World? International Regulatory Variation and Pharmaceutical Industry Location

Keywords: by Arthur Daemmrich; Pharmaceutical
  • 2001
  • Chapter

Publicly Funded Science and the Productivity of the Pharmaceutical Industry

By: Rebecca Henderson and Ian Cockburn
U.S. taxpayers funded $14.8 billion of health related research last year, four times the amount that was spent in 1970 in real terms. In this paper we evaluate the impact of these huge expenditures on the technological performance of the pharmaceutical industry. While... View Details
Keywords: Public Sector; Science-Based Business; Research and Development; Sovereign Finance; Pharmaceutical Industry
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Henderson, Rebecca, and Ian Cockburn. "Publicly Funded Science and the Productivity of the Pharmaceutical Industry." In Innovation Policy and the Economy, Volume 1, edited by Adam B. Jaffe, Josh Lerner, and Scott Stern, 1–34. MIT Press, 2001.
  • 2009
  • Working Paper

Social Influence Given (Partially) Deliberate Matching: Career Imprints in the Creation of Academic Entrepreneurs

By: Pierre Azoulay, Christopher C. Liu and Toby E. Stuart
Actors often match with associates on a small set of dimensions that matter most for the particular relationship at hand. In so doing, they are exposed to unanticipated social influences because counterparts have more interests, attitudes, and preferences than would-be... View Details
Keywords: Entrepreneurship; Patents; Marketplace Matching; Mathematical Methods; Science-Based Business; Power and Influence; Social and Collaborative Networks; Biotechnology Industry
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Azoulay, Pierre, Christopher C. Liu, and Toby E. Stuart. "Social Influence Given (Partially) Deliberate Matching: Career Imprints in the Creation of Academic Entrepreneurs." Harvard Business School Working Paper, No. 09-136, May 2009.
  • 28 Aug 2023
  • Research & Ideas

The Clock Is Ticking: 3 Ways to Manage Your Time Better

biomedical research institute. We measured employees’ daily work locations using building-badge swipe data, as well as various work and work-life outcomes via biweekly surveys. We found that each employee’s... View Details
Keywords: by Kristen Senz
  • 26 Jul 2024
  • Research & Ideas

Why Great Ideas Get Stuck in Universities

commercial hindrance. A recent study of more than 500 biomedical startups suggests that ventures rooted in the core research of their founders have a more challenging time reaching key measures of success,... View Details
Keywords: by Ben Rand; Biotechnology; Health
  • 13 Mar 2018
  • First Look

March 13, 2018

historians in recent years, academic research on business groups has, to date, remained within the boundary of emerging markets. The major aim of this volume is to explore the long-term evolution of different varieties of large... View Details
Keywords: Sean Silverthorne
  • 26 Mar 2012
  • Research & Ideas

What Neuroscience Tells Us About Consumer Desire

for behavior, and draws on concepts and techniques from neuroscience to inform her research in marketing. For corporations, on the other hand, the science is a means to an end goal of selling more stuff. But the tools, once restricted to... View Details
Keywords: by Carmen Nobel; Consumer Products
  • 28 Feb 2012
  • First Look

First Look: Feb. 28

Biomedical Research: Building a Sustainable, Globally Integrated Research Enterprise Vicki Sato, Christoph Jaeker, and Pooja Mehta SolankiHarvard Business School Case 612-048 As the head of the Novartis... View Details
Keywords: Sean Silverthorne
  • 23 Feb 2016
  • First Look

February 23, 2016

filing date rather than at patent grant—on the timing of licensing deals in the biomedical industry. We find that post-AIPA U.S. patent applications are significantly more likely to be licensed before patent grant and shortly after... View Details
Keywords: Sean Silverthorne
  • 12 Mar 2013
  • First Look

First Look: March 12

A. Arnaout Publication:Nature Biotechnology Abstract Advances in biotechnology have fueled the generation of unprecedented quantities of data across the life sciences. However, finding analysts who can address such "big data" problems effectively has become a... View Details
Keywords: Sean Silverthorne
  • 17 Sep 2013
  • First Look

First Look: September 17

Paul Healy, George Serafeim, and Devin Shanthikumar Abstract—Prior research on equity analysts focuses almost exclusively on those employed by sell-side investment banks and brokerage houses. Yet investment firms undertake their own... View Details
Keywords: Sean Silverthorne
  • 05 Sep 2012
  • First Look

First Look: September 5

hospitals and research centers to understand how colocation impacts the likelihood of scientific collaboration. We introduce exogenous colocation and face-to-face interactions for a random subset of View Details
Keywords: Sean Silverthorne
  • 03 Dec 2001
  • Research & Ideas

Healthcare Conference Looks At Ailing Industry

observations. Although healthcare as a whole still suffers from the elephant problem, it's suffering less all the time—at least where science is concerned—thanks to remarkable and ever-faster scientific advances. Chief among the advances is genomic View Details
Keywords: by Martha Lagace; Health
  • 13 Jan 2003
  • Research & Ideas

Making Biotech Work as a Business

low return. He also offered strategic pointers for companies immersed in the field. Suddenly, with the ability to monetize IP, there was a new freedom.— Gary P. Pisano At moments during Pisano's talk, titled "The Biomedical... View Details
Keywords: by Martha Lagace; Biotechnology; Health; Technology
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