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  • December 2008 (Revised January 2011)
  • Case

Arcadia Biosciences: Seeds of Change

By: Arthur A. Daemmrich, Forest L. Reinhardt and Mary Louise Shelman
Arcadia Biosciences is an entrepreneurial California agricultural biotech company seeking to earn carbon credits by modifying commodity crops for use in China and India. Eric Rey, Arcadia's CEO, faced a strategic inflection point in early September 2008. The company... View Details
Keywords: Business Startups; Entrepreneurship; Growth and Development Strategy; Environmental Sustainability; Science-Based Business; Climate Change; Agriculture and Agribusiness Industry; Biotechnology Industry; China; India; California
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Daemmrich, Arthur A., Forest L. Reinhardt, and Mary Louise Shelman. "Arcadia Biosciences: Seeds of Change." Harvard Business School Case 709-019, December 2008. (Revised January 2011.)
  • 03 Dec 2001
  • Research & Ideas

Healthcare Conference Looks At Ailing Industry

Mixing Risk And Reward The basic model that the biotechnology industry has followed for over twenty years is also changing, and for the better, according to panelists at a session titled "Will Equal Biotechnology-Pharma Partnerships... View Details
Keywords: by Martha Lagace; Health
  • July 2013
  • Case

Novozymes: Establishing the Cellulosic Ethanol Value Chain

By: Willy Shih and Sen Chai

As the world's largest producer of industrial enzymes, Novozymes had invested heavily for many years to bio-engineer enzymes that could break down cellulose into fermentable sugar. In 2010, the company had launched what it thought would become a breakthrough product... View Details

Keywords: System Complexity; Industrial Enzymes; Ethanol; Collulosic Ethanol; Fermentation; Genomics; Genetic Engineering; Value Chain; Assembling Value Chain; Energy Sources; Renewable Energy; Collaborative Innovation and Invention; Innovation and Management; Innovation Strategy; Technological Innovation; Management; Growth and Development Strategy; Industry Growth; Production; Research; Research and Development; Science; Genetics; Natural Environment; Environmental Sustainability; Science-Based Business; Business Strategy; Commercialization; Vertical Integration; Agriculture and Agribusiness Industry; Biotechnology Industry; Energy Industry; Denmark; United States
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Shih, Willy, and Sen Chai. "Novozymes: Establishing the Cellulosic Ethanol Value Chain." Harvard Business School Case 614-001, July 2013.
  • 14 Jul 2009
  • First Look

First Look: July 14

biotechnology deals. Purchase this case: http://hbsp.harvard.edu/b01/en/common/item_detail.jhtml?id=309112 Goldman Sachs: The 10,000 Women Initiative Harvard Business School Case 509-042 Describes the conception, development, and... View Details
Keywords: Martha Lagace
  • 17 Oct 2006
  • First Look

First Look: October 17, 2006

started her own hedge fund firm in 2001 after nearly 20 years as a star biotechnology analyst and hedge fund manager. After the start-up phase, her firm became highly profitable. In 2004, however, one of her four analysts lost a lot of... View Details
Keywords: Sean Silverthorne
  • 11 May 2010
  • First Look

First Look: May 11

Amyris Biotechnologies: Commercializing Biofuel Gary P. Pisano and Alison Berkley WagonfeldHarvard Business School Case 610-031 In 2009, Amyris Biotechnologies was building a plant in Brazil that used synthetic biology to convert... View Details
Keywords: Martha Lagace
  • September 2012 (Revised January 2014)
  • Case

Aqua Bounty

By: Lucy White and Stephen Burn-Murdoch
Valuation of a pre-revenue biotech company at IPO using probability trees and real option techniques. Company is based in Massachusetts and lists in London on AIM. Products are genetically-modified fast-growing salmon for fish farmers and disease-prevention drugs and... View Details
Keywords: IPO; Valuation; Real Options; Decision Tree; Biotech; Genetically Modified; Salmon; Entrepreneurship; Finance; Biotechnology Industry; Biotechnology Industry; North and Central America; Europe; South America
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White, Lucy, and Stephen Burn-Murdoch. "Aqua Bounty." Harvard Business School Case 213-047, September 2012. (Revised January 2014.)
  • September 2000
  • Case

Novartis Agricultural Discovery Institute (A)

Steve Briggs, a PhD biologist, is asked to propose a strategy to take global life-science giant Novartis into the rapidly expanding field of plant genomics. View Details
Keywords: Design; Plant-Based Agribusiness; Genetics; Infrastructure; Biotechnology Industry; Biotechnology Industry
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West, Jonathan, and Christian G. Kasper. "Novartis Agricultural Discovery Institute (A)." Harvard Business School Case 601-010, September 2000.
  • April 1998 (Revised June 1998)
  • Supplement

Pioneer Hi-Bred International, Inc.: Supply Management (Addendum)

By: Francis Aguilar, Paul Clark and Xin Xi He
Addendum to case. View Details
Keywords: Biotechnology Industry; Biotechnology Industry
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Aguilar, Francis, Paul Clark, and Xin Xi He. "Pioneer Hi-Bred International, Inc.: Supply Management (Addendum)." Harvard Business School Supplement 898-239, April 1998. (Revised June 1998.)
  • October 1998 (Revised December 1999)
  • Case

Gene Research, the Mapping of Life and the Global Economy

By: Ray A. Goldberg and Juan Enriquez-Cabot
A new firm is being created to speed up the process of mapping humans, animals, and plants by combining gene technology with rapid gene identification to improve the health and well being of the human population and the productivity of crops and animals. How does one... View Details
Keywords: Information Technology; Organizational Structure; Technological Innovation; Business Processes; Health Care and Treatment; Performance Productivity; Welfare; Agribusiness; Genetics; Science-Based Business; Biotechnology Industry; Biotechnology Industry
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Goldberg, Ray A., and Juan Enriquez-Cabot. "Gene Research, the Mapping of Life and the Global Economy." Harvard Business School Case 599-016, October 1998. (Revised December 1999.)
  • 09 Apr 2012
  • Research & Ideas

Who Sways the USDA on GMO Approvals?

Many corporations have gotten good at pulling the levers of government to tilt the odds in their favor, weakening regulations or securing perks, justified or not, to further their business interests. Economists use the term "regulatory capture" to describe... View Details
Keywords: by Michael Blanding; Biotechnology; Biotechnology; Biotechnology
  • September 2013 (Revised August 2014)
  • Case

Claritas Genomics

By: Robert F. Higgins and Matthew Preble
Claritas Genomics was formed in January 2013 when BCH spun out its Genetics Diagnostic Lab into a fully commercial entity. Claritas offered over 100 genomic tests to detect a range of conditions, including autism and intellectual disabilities, and was developing new... View Details
Keywords: Boston Children's Hospital; Genetic Engineering; Genetically Modified; Genetics Diagnostics; Health Care Industry; Healthcare IT; Healthcare Technology; Healthcare Ventures; Biomedical Research; Patrice Milos; Genomics; Genomic Testing; Life Technologies; Health Care and Treatment; Information Technology; Information Management; Genetics; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Boston; Massachusetts; United States
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Higgins, Robert F., and Matthew Preble. "Claritas Genomics." Harvard Business School Case 814-032, September 2013. (Revised August 2014.)
  • September 2008
  • Background Note

Background on the Technology of Molecular Diagnostics

By: Regina E. Herzlinger and Jason Sanders
To be used as background reading for the "EXACT Sciences Corp.: Commercializing a Diagnostic Test" and "Diagnostic Genomics" cases, HBS nos. 308-090 and 309-040. View Details
Keywords: Health Testing and Trials; Technology; Biotechnology Industry; Biotechnology Industry
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Herzlinger, Regina E., and Jason Sanders. "Background on the Technology of Molecular Diagnostics." Harvard Business School Background Note 309-050, September 2008.
  • Aug 2011 - 2011
  • Conference Presentation

Institutional Heterogeneity, Innovation, and Entrepreneurship in the U.S. Biodiesel Fuel Sector

By: Shon R. Hiatt
Keywords: Innovation and Invention; Entrepreneurship; Business Ventures; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry
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Hiatt, Shon R. "Institutional Heterogeneity, Innovation, and Entrepreneurship in the U.S. Biodiesel Fuel Sector." Paper presented at the Academy of Management Annual Meeting, San Antonio, TX, August 2011.
  • 2011
  • Other Unpublished Work

From Farms to Fuel Tanks: Collective Actors and New-Venture Innovation in the U.S. Biodiesel Fuel Sector

By: Shon R. Hiatt
Little is known about the influence of collective actors on innovative technological recombinations by new ventures. Using data from U.S. biodiesel producers, I examine how the efforts of multiple collective actors (farm associations) to promote varying types of... View Details
Keywords: Alliances; Agribusiness; Energy Sources; Innovation and Invention; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; United States
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Hiatt, Shon R. "From Farms to Fuel Tanks: Collective Actors and New-Venture Innovation in the U.S. Biodiesel Fuel Sector." 2011.
  • Research Summary

Evolution of firm structure in vertical specialized technology supply chains

By: Willy C. Shih
The global market in many everyday products has been transformed by the internationalization of production.  In many industries, semiconductors and electronic products in particular, a sequential mode of production has evolved in which goods are produced... View Details
Keywords: Globalization Of Supply Chain; Globalization; Technological Innovation; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; United States; Asia; China
  • Research Summary

Industrial competitiveness in high tech and science-based businesses

By: Willy C. Shih
How do emerging economies develop industrial and technical capabilities that overtake those of advanced economies?  Are there some industrial sectors that are especially susceptible to such targeting?  What will it take to restore America’s... View Details
Keywords: Technological Innovation; Technology Diffusion; Knowledge Flows; Competitive Advantage; Globalization; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; United States; China; Asia
  • September 2019
  • Case

Bill & Melinda Gates Foundation: Shaping the Vaccine Manufacturing Ecosystem

By: Willy C. Shih
Vaccines for children has been a long-standing focus for the Bill & Melinda Gates Foundation, and its critical role in public health made its production an important economic and political issue. This case describes the Foundation's investment in a breakthrough vaccine... View Details
Keywords: Vaccine; Production; Supply Chain; Product; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Belgium
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Shih, Willy C. "Bill & Melinda Gates Foundation: Shaping the Vaccine Manufacturing Ecosystem." Harvard Business School Case 620-021, September 2019.
  • June 2010
  • Teaching Note

Monsanto: Helping Farmers Feed the World (TN)

By: David E. Bell and Mary Louise Shelman
Teaching Note for [510025]. View Details
Keywords: Food; Production; Adoption; Leadership Style; Globalized Markets and Industries; Performance Productivity; Biotechnology Industry; Biotechnology Industry
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Bell, David E., and Mary Louise Shelman. "Monsanto: Helping Farmers Feed the World (TN)." Harvard Business School Teaching Note 510-101, June 2010.
  • March 2010 (Revised May 2012)
  • Case

Myelin Repair Foundation: Accelerating Drug Discovery Through Collaboration

By: Karim R. Lakhani and Paul R. Carlile
This case presents the Myelin Repair Foundation's accelerated research collaboration model for drug discovery. It highlights the challenges of building a multi-disciplinary and multi-institutional research collaboration that is attempting to create a treatment for... View Details
Keywords: Research and Development; Intellectual Property; Risk and Uncertainty; Strategic Planning; Collaborative Innovation and Invention; Health Disorders; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry
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Lakhani, Karim R., and Paul R. Carlile. "Myelin Repair Foundation: Accelerating Drug Discovery Through Collaboration." Harvard Business School Case 610-074, March 2010. (Revised May 2012.)
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