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  • All HBS Web  (4,646)
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  • December 2006 (Revised August 2008)
  • Case

Pervasis Therapeutics, Inc.

By: Robert F. Higgins and Virginia Fuller
In May 2005, Steve Bollinger was about to become president and chief operating officer of Pervasis Therapeutics, a small cell therapy start-up in Cambridge, Mass. If proven successful, Pervasis' product, Vascugel, could change the way vascular disease is treated and... View Details
Keywords: Business Startups; Venture Capital; Financial Strategy; Governing Rules, Regulations, and Reforms; Health Care and Treatment; Health Testing and Trials; Health Industry; Cambridge
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Higgins, Robert F., and Virginia Fuller. "Pervasis Therapeutics, Inc." Harvard Business School Case 807-026, December 2006. (Revised August 2008.)
  • 02 Feb 2007
  • What Do You Think?

Is There Too Little “Know Why” In Business?

Summing Up The central debate among respondents to this month's column was joined early when the first respondent, Aaron Tice, commented, "Without the execution of business objectives in the pursuit of... View Details
Keywords: by Jim Heskett
  • 01 Jun 2015
  • News

Lessons from a Megacity

capital by foot, subte (subway), bus, and bright yellow bike-share bicycles. Pedestrian-only Florida Street in Buenos Aires. (Photos courtesy of John Macomber) Professor Macomber and students at the new electric power and water... View Details
Keywords: April White; Transit and Ground Passenger Transportation; Transportation
  • 14 Oct 2008
  • Research & Ideas

Should You Bring Advertising Expertise In-House?

campaign compare when the tasks are performed internally rather than by an independent outside agency? Ownership of an in-house agency rests with the advertiser and allows the advertiser greater control over... View Details
Keywords: by Sarah Jane Gilbert; Advertising
  • 03 Feb 2015
  • First Look

First Look: February 3

databases). We also show that it reveals the main "flow of control" within the architecture, as denoted by the classification of components into Core, Peripheral, Shared, and View Details
Keywords: Sean Silverthorne
  • 06 Apr 2023
  • Blog Post

Circularity in Denmark

there were two main takeaways: the use of a foundation and co-op corporate structures to better enable progress towards sustainability goals, and the distribution of sustainability roles across multiple... View Details
  • 08 Jul 2015
  • What Do You Think?

Do Americans Work Too Much and Think About Work Too Little?

such as the Ritz-Carlton, employees meet at the outset of each shift on company time to discuss potential problems, how they can be addressed, and ways of working smarter. View Details
Keywords: by James Heskett; Financial Services
  • 17 May 2010
  • Research & Ideas

What Brazil Teaches About Investor Protection

dissertation, the World Bank, the International Corporate Governance Network, the OCDE, and so on were promoting this principle as a way to overcome the abuses of managers or controlling shareholders who... View Details
Keywords: by Sean Silverthorne; Banking; Financial Services
  • 01 Dec 2013
  • News

14 for '14

breakup of nations continues: The economic crisis and the concentration of the knowledge economy in a few cities creates enormous incentives for regions to cast off. They begin by demanding ever-greater... View Details
Keywords: Arts, Entertainment; Finance; Government; Information; Retail Trade
  • 25 Aug 2022
  • News

The Exchange: The Road Ahead for Crypto

submerge nearly all of the crypto-ness under the hood, and the fact that it’s managed on a blockchain is just how they make the architecture work. The thing that will be helpful for consumers is the fact that, with these crypto... View Details
Keywords: Jen McFarland Flint; Securities, Commodities, and Other Financial Investments; Finance
  • 08 Jul 2014
  • First Look

First Look: July 8

  Publications 2014 AMACOM Own Your Future: How to Think Like an Entrepreneur and Thrive in an Unpredictable Economy By: Brown, Paul B., Charles F. Kiefer, and Leonard A. Schlesinger Abstract—It used to be that if you studied and worked hard, you could be assured View Details
Keywords: Carmen Nobel
  • 07 Dec 2016
  • HBS Case

Why Millennials Flock to Fintech for Personal Investing

stocks do very well over a period of time relative to other asset classes and become too large a percentage of the portfolio, the robo-advisor automatically reinvests in the other asset classes to View Details
Keywords: by Michael Blanding; Financial Services
  • 08 Feb 2011
  • First Look

First Look: Feb. 8

of causes. System-level accidents occur when anomalies or errors in different parts of an interconnected system negatively reinforce one another, spiraling up out of View Details
Keywords: Sean Silverthorne
  • 16 Jun 2023
  • Blog Post

Improve Decision-Making in Hiring: Common Pitfalls and How to Avoid Them

pool. Be aware of how video background and noise out of a candidate’s control influence your perception and offer alternatives. Standardize your interview process so that each... View Details
Keywords: All Industries
  • May 18, 2012
  • Article

Randomized Government Safety Inspections Reduce Worker Injuries with No Detectable Job Loss

By: David I Levine, Michael W. Toffel and Matthew S. Johnson
Controversy surrounds occupational health and safety regulators, with some observers claiming that workplace regulations damage firms' competitiveness and destroy jobs and others arguing that they make workplaces safer at little cost to employers and employees. We... View Details
Keywords: Regulation; Occupational Safety; Evaluation; Regression; Matching; Difference In Differences; Safety; Health; Working Conditions; Governing Rules, Regulations, and Reforms; Competitive Advantage; Performance; Manufacturing Industry; California
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Levine, David I., Michael W. Toffel, and Matthew S. Johnson. "Randomized Government Safety Inspections Reduce Worker Injuries with No Detectable Job Loss." Science 336, no. 6083 (May 18, 2012): 907–911. (Online supplement (appendix). Featured in an article by the head of US OSHA, and in U.S. News & World Report and many other news outlets. Basis of U.S. Congressional testimony on promoting safe workplaces.)
  • 17 Nov 2020
  • In Practice

How Retailers Can Thrive in a Shopping Season Like No Other

promotions to control the flow of shoppers inside stores to meet social distancing requirements. Many started offering Black Friday deals in early November. Discounts appear to be larger than ever this year,... View Details
Keywords: by Danielle Kost; Retail
  • 03 Mar 2014
  • HBS Case

Decommoditizing the Canned Tomato

techniques—though Francesco admits in the case that this is an uphill battle. The way Francesco handles quality control inside the plant is especially unique. While most companies package and label their products separately, the bulk... View Details
Keywords: by Maggie Starvish; Agriculture & Agribusiness; Food & Beverage; Retail
  • 29 Apr 2008
  • First Look

First Look: April 29, 2008

through each phase of this process. The (A) case begins with background on the firm and asks the students to come up with a strategy to improve the way in which Sales and Marketing work together. In the (B) case, we see their strategy in... View Details
Keywords: Martha Lagace
  • 12 Jul 2011
  • First Look

First Look: July 12

been abandoned by its owners and had come under the control of CW Capital, the special servicer for the vast amount of debt that was in default. Any investment in a distressed... View Details
Keywords: Carmen Nobel
  • 24 Dec 2013
  • First Look

First Look: December 24

alternative financing models of corporate lenders, including banks and finance companies.) The second major component of the case concerns distressed debt investment strategies and provides an illustration... View Details
Keywords: Carmen Nobel
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