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      • Faculty Publications  (509)

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      • June 2004
      • Case

      Aventis SA (B): A Company is Born

      By: Joshua D. Margolis and Carin-Isabel Knoop
      Supplements the (A) case. View Details
      Keywords: Problems and Challenges; Mergers and Acquisitions; Horizontal Integration; Organizational Design; Organizational Culture; Pharmaceutical Industry; United States
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      Margolis, Joshua D., and Carin-Isabel Knoop. "Aventis SA (B): A Company is Born." Harvard Business School Case 404-108, June 2004.
      • June 2004 (Revised June 2006)
      • Supplement

      Vertex Pharmaceuticals: R&D Portfolio Management (A)

      By: Gary P. Pisano, Lee Fleming and Eli Strick
      Vertex Pharmaceuticals, Inc., a drug discovery company that recently decided to pursue a vertically integrated business model, chose to build up its clinical development and commercial capabilities and infrastructure. For the first time in its history, Vertex will... View Details
      Keywords: Research and Development; Investment Portfolio; Pharmaceutical Industry
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      Pisano, Gary P., Lee Fleming, and Eli Strick. "Vertex Pharmaceuticals: R&D Portfolio Management (A)." Harvard Business School Supplement 604-101, June 2004. (Revised June 2006.)
      • May 2004 (Revised June 2004)
      • Case

      Brief Biographical Note on P. Roy Vagelos

      By: Nitin Nohria and Bridget Gurtler
      Provides background biographical information on P. Roy Vagelos, chief executive officer of Merck Pharmaceuticals. Teaching Purpose: To chart the development of a leader in the pharmaceutical industry. View Details
      Keywords: Biography; Teaching; Leadership Development; Mission and Purpose; Personal Development and Career; Ethics; Pharmaceutical Industry
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      Nohria, Nitin, and Bridget Gurtler. "Brief Biographical Note on P. Roy Vagelos." Harvard Business School Case 404-132, May 2004. (Revised June 2004.)
      • March 2004 (Revised July 2004)
      • Case

      UCB: Managing Information for Globalization and Innovation (A) (Abridged)

      By: F. Warren McFarlan and Brian DeLacey
      A medium-size European manufacturer of pharmaceuticals and chemicals faces a number of information strategy issues. The case focuses on the issues of coordinating international IT activities and day-to-day operations as well as balancing the company's IT applications... View Details
      Keywords: Innovation and Invention; Information Technology; Operations; System; Corporate Strategy; Investment Portfolio; Globalization; Pharmaceutical Industry; Pharmaceutical Industry; Brussels
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      McFarlan, F. Warren, and Brian DeLacey. "UCB: Managing Information for Globalization and Innovation (A) (Abridged)." Harvard Business School Case 304-096, March 2004. (Revised July 2004.)
      • August 2003
      • Teaching Note

      Pharmacyclics: Financing Research and Development (TN)

      By: Malcolm P. Baker and Richard S. Ruback
      Teaching Note for (9-201-056). View Details
      Keywords: Pharmaceutical Industry; Pharmaceutical Industry
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      Baker, Malcolm P., and Richard S. Ruback. "Pharmacyclics: Financing Research and Development (TN)." Harvard Business School Teaching Note 204-012, August 2003.
      • August 2003 (Revised August 2006)
      • Case

      New Sector Alliance (A): An Entry into Health Care?

      By: Regina E. Herzlinger, Stacy Smollin Schwartz and Jeffrey Cronin
      Describes the structure of the U.S. health care system and presents a study of a nonprofit consulting firm that hopes to enter the health care system. Includes descriptions of hospitals, doctors, insurers, medical technology providers, medical devices, pharmaceuticals,... View Details
      Keywords: Health; Health Care and Treatment; Health Disorders; Nonprofit Organizations; Health Industry; United States
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      Herzlinger, Regina E., Stacy Smollin Schwartz, and Jeffrey Cronin. "New Sector Alliance (A): An Entry into Health Care?" Harvard Business School Case 304-004, August 2003. (Revised August 2006.)
      • June 2003 (Revised October 2004)
      • Case

      Novartis: The Challenge of Success (C)

      By: Sandra J. Sucher and Stacy McManus
      Supplements the (A) and (B) cases. View Details
      Keywords: Pharmaceutical Industry; Pharmaceutical Industry
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      Sucher, Sandra J., and Stacy McManus. "Novartis: The Challenge of Success (C)." Harvard Business School Case 603-045, June 2003. (Revised October 2004.)
      • June 2003 (Revised October 2004)
      • Case

      Novartis: The Challenge of Success (D)

      By: Sandra J. Sucher and Stacy McManus
      Supplements the (A) and (B) cases. View Details
      Keywords: Pharmaceutical Industry; Pharmaceutical Industry
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      Sucher, Sandra J., and Stacy McManus. "Novartis: The Challenge of Success (D)." Harvard Business School Case 603-046, June 2003. (Revised October 2004.)
      • June 2003 (Revised March 2008)
      • Case

      Schering-Plough and Genome Therapeutics: Discovering an Asthma Gene

      By: Regina E. Herzlinger and Marc Aquino
      Personalized medicine requires the identification of mutated genes. Schering-Plough's search for the one related to asthma requires finding families with the disease. Examines the industry that helps conduct such research, including contract research organizations. View Details
      Keywords: Health Disorders; Research and Development; Genetics; Pharmaceutical Industry; Pharmaceutical Industry
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      Herzlinger, Regina E., and Marc Aquino. "Schering-Plough and Genome Therapeutics: Discovering an Asthma Gene." Harvard Business School Case 303-044, June 2003. (Revised March 2008.)
      • June 2003 (Revised May 2006)
      • Case

      Cipla

      By: Rohit Deshpande and Laura Winig
      The head of Cipla, a $325-million-dollar Indian pharmaceutical company and seller of low-cost AIDS drugs to South Africa, must decide what to do about Cipla's future. With India poised to enforce international patents in only two years, much of Cipla's product line... View Details
      Keywords: Trade; Price; Global Strategy; Health Care and Treatment; Patents; Leadership; Marketing Strategy; Health Industry; South Africa; India
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      Deshpande, Rohit, and Laura Winig. "Cipla." Harvard Business School Case 503-085, June 2003. (Revised May 2006.)
      • June 2003
      • Teaching Note

      Discovering the Future: R&D Strategy at Merck (TN)

      By: Gary P. Pisano
      Teaching Note for (9-601-086). View Details
      Keywords: Pharmaceutical Industry
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      Pisano, Gary P. "Discovering the Future: R&D Strategy at Merck (TN)." Harvard Business School Teaching Note 603-137, June 2003.
      • April 2003 (Revised October 2004)
      • Case

      Novartis: The Challenge of Success (A)

      By: Sandra J. Sucher and Stacy McManus
      Preliminary results from Phase 1 clinical trials of a newly developed compound, STI571, showed that 31 out of 31 patients with chronic myelogenous leukemia (CML) had their blood counts return to normal. In the world of oncology, this was unheard of. This was the... View Details
      Keywords: Decision Making; Health Testing and Trials; Innovation and Invention; Markets; Distribution; Product Development; Production; Problems and Challenges; Research; Research and Development; Complexity; Pharmaceutical Industry; Pharmaceutical Industry
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      Sucher, Sandra J., and Stacy McManus. "Novartis: The Challenge of Success (A)." Harvard Business School Case 603-043, April 2003. (Revised October 2004.)
      • April 2003 (Revised October 2004)
      • Case

      Novartis: The Challenge of Success (B)

      By: Sandra J. Sucher and Stacy McManus
      When Dr. Daniel Vasella learned of the early Phase 1 trial results, he immediately decided what course of action Novartis would take. Students will be able to examine and assess the concrete steps, and the rationale behind them, that Novartis took in response to this... View Details
      Keywords: Decision Making; Moral Sensibility; Innovation and Invention; Distribution; Product Development; Production; Problems and Challenges; Research and Development; Pharmaceutical Industry; Pharmaceutical Industry
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      Sucher, Sandra J., and Stacy McManus. "Novartis: The Challenge of Success (B)." Harvard Business School Case 603-044, April 2003. (Revised October 2004.)
      • February 2003 (Revised April 2004)
      • Case

      Pharmaceutical Industry, The: Challenges in the New Century

      By: Stephen P. Bradley and James Weber
      Provides a broad overview of the numerous internal and external forces that were driving change in the global pharmaceutical industry in 2003. These forces--including downward price pressures, political and social pressures, increased development costs, new... View Details
      Keywords: Business Model; Change; Cost; Price; Globalization; Government and Politics; Brands and Branding; Industry Growth; Society; Competition; Consolidation; Technology; Pharmaceutical Industry
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      Bradley, Stephen P., and James Weber. "Pharmaceutical Industry, The: Challenges in the New Century." Harvard Business School Case 703-489, February 2003. (Revised April 2004.)
      • February 2003 (Revised August 2005)
      • Case

      UCB (A): Managing Information for Globalization and Innovation

      By: F. Warren McFarlan and Brian DeLacey
      This case presents a complex total MIS strategy case for a $3 billion European pharmaceutical/chemicals company based in Brussels. It covers corporate strategy alignment of IT portfolio, IT operations issues, and global coordination of IT. View Details
      Keywords: Information Technology; Operations; System; Corporate Strategy; Investment Portfolio; Globalization; Pharmaceutical Industry; Pharmaceutical Industry; Brussels
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      McFarlan, F. Warren, and Brian DeLacey. "UCB (A): Managing Information for Globalization and Innovation." Harvard Business School Case 303-091, February 2003. (Revised August 2005.)
      • Article

      Discontinuities and Senior Management: Assessing the Role of Recognition in Pharmaceutical Firm Response to Biotechnology

      By: Rebecca M. Henderson, Sarah Kaplan and Fiona Murray
      Keywords: Management; Science; Technology; Biotechnology Industry
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      Henderson, Rebecca M., Sarah Kaplan, and Fiona Murray. "Discontinuities and Senior Management: Assessing the Role of Recognition in Pharmaceutical Firm Response to Biotechnology." Industrial and Corporate Change 12, no. 2 (April 2003).
      • December 2002
      • Teaching Note

      Abgenix and the XenoMouse (TN)

      By: John T. Gourville
      Teaching Note for (501-061). View Details
      Keywords: Health Testing and Trials; Decision Choices and Conditions; Sales; Product Development; Joint Ventures; Pharmaceutical Industry; Pharmaceutical Industry
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      Gourville, John T. "Abgenix and the XenoMouse (TN)." Harvard Business School Teaching Note 503-046, December 2002.
      • December 2002
      • Article

      Knowledge Seeking and Location Choice of Foreign Direct Investment in the United States

      By: Juan Alcacer and Wilbur Chung
      To what extent do firms go abroad to access technology available in other locations? This paper examines whether and when state technical capabilities attract foreign investment in manufacturing from 1987-1993. We find that on average state R&D intensity does not... View Details
      Keywords: Knowledge Acquisition; Foreign Direct Investment; Research and Development; Information Technology; Production; Geographic Location; United States
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      Alcacer, Juan, and Wilbur Chung. "Knowledge Seeking and Location Choice of Foreign Direct Investment in the United States." Management Science 48, no. 12 (December 2002): 1534–1554.
      • November 2002
      • Compilation

      Four Principles of Biomedical Ethics: Definitions and Examples

      By: Sandra J. Sucher
      Introduces four principles of biomedical ethics, excerpted from Principles of Biomedical Ethics, Tom L. Beauchamp and James F. Childress (Oxford University Press, 2001). The principles provide a conceptual framework for the analysis and resolution of moral problems... View Details
      Keywords: Framework; Moral Sensibility; Health Care and Treatment; Distribution; Problems and Challenges; Research; Emotions; Management Analysis, Tools, and Techniques; Pharmaceutical Industry; Pharmaceutical Industry
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      Sucher, Sandra J. "Four Principles of Biomedical Ethics: Definitions and Examples." Harvard Business School Compilation 603-079, November 2002.
      • October 2002 (Revised June 2003)
      • Background Note

      New Frontiers in Target Discovery and Validation

      By: Regina E. Herzlinger, Niv Caviar, Jon Chatterton and Andrea Lynn
      Explains Immusol and Novartis's technology. View Details
      Keywords: Information Technology; Technological Innovation; Pharmaceutical Industry
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      Herzlinger, Regina E., Niv Caviar, Jon Chatterton, and Andrea Lynn. "New Frontiers in Target Discovery and Validation." Harvard Business School Background Note 303-054, October 2002. (Revised June 2003.)
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