Publications

May 2021
Case

Inclusive Innovation at Mass General Brigham

By: Katherine Baldiga Coffman and Olivia Hull

Massachusetts General Brigham (MGB) Chief Innovation Officer Christopher Coburn had overseen a period of exciting transformation and growth in healthcare innovation at MGB. In November 2019, the health system was the largest recipient of National Institutes of Health... View Details

24 Jan 2017
First Look

First Look at New Research: January 24, 2017

Publisher's link: https://www.hbs.edu/faculty/Pages/item.aspx?num=52122 January 2017 Strategic Finance Managing Healthcare Costs and Value By: Kaplan, Robert S., Michael E. Porter, and Mark L. Frigo Abstract—Rising health care costs are a... View Details

Keywords: Sean Silverthorne

30 Apr 2024
Book

When Managers Set Unrealistic Expectations, Employees Cut Ethical Corners

decisions that were so clearly disastrous not only for workers and others exposed to asbestos but for the company itself. Shortly thereafter, in 1982, with its asbestos-related liabilities projected to exceed its assets, Johns-Manville shocked the business world by... View Details

Keywords: by Dina Gerdeman

September 2014
Case

FormPrint Ortho500

By: Frank V. Cespedes and Alisa Zalosh

The Senior Vice President of FormPrint's Medical Products business unit is considering issues raised by the upcoming introduction of a new 3D printing system, the Ortho500, which could print custom exoskeletal orthopedic splints, braces, and casts that conformed to a... View Details

Keywords: B2B Marketing; Technological Innovation; Market Entry and Exit; Marketing Strategy; Distribution Channels; Product Development; Medical Devices and Supplies Industry

29 Sep 2015
First Look

September 29, 2015

innovations from industry outsiders who saw economic opportunities where others didn’t—and how these mainstream firms had no choice but to innovate themselves. New models were tried: some succeeded, some failed. Commercial markets turned... View Details

Keywords: Sean Silverthorne

August 2012 (Revised July 2025)
Module Note

Evaluating the Viability of Innovative Technology-Commercializing Ventures

By: Regina E. Herzlinger

This case enables evaluation of innovative health care technologies by those who are not an expert in the technology by introduction of a framework for evaluating technology - commercializing innovation. It is the introductory case for the first of four modules in a... View Details

Keywords: Medical Devices and Supplies Industry; Medical Devices and Supplies Industry

November 2022
Case

The Battle Among Channels for Marketing Pharmaceuticals: UpScript, Pharmacy Benefit Managers, and Direct-to-Consumer Sales

By: Regina E. Herzlinger and Tiffany Farrell

Can an online, direct-to-consumer pharmacy both improve the quality and speed of care for patients who need branded drugs and stabilize profits for pharmaceutical manufacturers? UpScript, after years spent achieving legal and regulatory compliance and simultaneous... View Details

Keywords: DTC; Internet and the Web; Marketing Channels; Customer Value and Value Chain; Governing Rules, Regulations, and Reforms; Competitive Strategy; Service Delivery; Growth and Development Strategy; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry

August 2023 (Revised October 2023)
Case

Beyond the Barricades: Chile 2023

By: Debora Spar, Willis Emmons, Leonard A. Schlesinger and Ruth Costas

Chile, often considered among Latin America's greatest economic success stories, suffered a shocking wave of protests in October 2019, as its citizens demanded reforms across healthcare and education systems, and protested inequality and rising costs of living. As... View Details

Keywords: Government Administration; Developing Countries and Economies; Economic Growth; Social Issues; Wealth and Poverty; Public Opinion; Equality and Inequality; Public Administration Industry; Chile; Latin America; South America

January 2023
Case

Cleave Therapeutics: Taking a Risk on Oncology Drug Discovery

By: Regina Herzlinger and Brian Walker

What should a successful executive (HBS Baker Scholar) assess as her next move as the CEO of a firm with a promising and yet uncertain new drug? Amy Burroughs’ mandate to successfully commercialize Cleave Therapeutics’ drug for a cancer with no current successful... View Details

Keywords: Product Development; Leadership; Health Testing and Trials; Research and Development; Risk and Uncertainty; Financial Condition; Partners and Partnerships; Pharmaceutical Industry

2023
Article

Dynamic HTA for Digital Health Solutions: Opportunities and Challenges for Patient-Centered Evaluation

By: Jan B. Brönneke, Annika Herr, Simon Reif and Ariel D. Stern

Germany’s 2019 Digital Healthcare Act (Digitale-Versorgung-Gesetz, or DVG) created a number of opportunities for the digital transformation of the health care delivery system. Key among these was the creation of a reimbursement pathway for patient-centered digital... View Details

Keywords: Digital Transformation; Applications and Software; Product Development; Insurance; Policy; Health Industry; Germany

Read Now

26 Sep 2006
First Look

First Look: September 26, 2006

patient needs and working backwards to develop profitable solutions rather than starting with the government, pharmaceutical or healthcare industry or NGO. The examination is undertaken on two levels, a... View Details

Keywords: Sean Silverthorne

26 Oct 2010
First Look

First Look: October 26, 2010

initiative with domestic, international, and U.N. fronts; and 3) launching a new venture requiring internal, capital-raising, licensing, and industrial partnering deals. The need to negotiate multiple, related deals is not new to... View Details

Keywords: Sean Silverthorne

September 2011 (Revised January 2012)
Case

Telemonitoring at Visiting Nurse Health System

By: F. Warren McFarlan, Mark Keil and Mala Kaul

The Telemonitoring at Visiting Nurse Health System case presents one home healthcare organization's efforts to use telemonitoring to improve the quality of care provided to at-risk patients who were discharged from hospitals and needed home care. After two years of... View Details

Keywords: Capital Budgeting; Cost vs Benefits; Risk Management; Technology Adoption; Technological Innovation; Organizational Change and Adaptation; Competitive Strategy; Health Industry; Health Industry

2015
Book

Political Standards: Corporate Interest, Ideology, and Leadership in the Shaping of Accounting Rules for the Market Economy

By: Karthik Ramanna

There are certain institutions underlying our modern market-capitalist system that are largely outside the interest and understanding of the general public—e.g., rulemaking for bank capital adequacy, actuarial standards, accounting standards, and auditing practice. In... View Details

Keywords: Business And Society; Financial Institutions; Financial Reporting; GAAP; IFRS; Lobbying; Capitalism; Sustainability; Accounting; Finance; Business and Government Relations; Leadership; Accounting Industry; Accounting Industry; United States; China; India

Find at Harvard

30 May 2007
Research & Ideas

Health Care Under a Research Microscope

players, poor customer service, and regional variations in quality of care. "By virtually any standard, it's an underperforming industry," says Richard Hamermesh, faculty chair of Harvard Business School's recently formed View Details

Keywords: by Sean Silverthorne; Health; Biotechnology

03 Nov 2009
First Look

First Look: Nov. 3

listed and unlisted firms from across a wide spectrum of manufacturing and services industries and ownership structures such as state-owned firms, business groups, and private and foreign firms. Detailed balance sheet and ownership... View Details

Keywords: Martha Lagace

02 Feb 2016
First Look

February 2, 2016

Interorganizational Network Forms By: Tatarynowicz, Adam, Maxim Sytch, and Ranjay Gulati Abstract—This study investigates the origins of variation in the structures of interorganizational networks across industries. We combine empirical analyses of existing... View Details

Keywords: Sean Silverthorne

September 2015
Article

Design and Implementation of a Privacy Preserving Electronic Health Record Linkage Tool in Chicago

By: Abel Kho, John Cashy, Kathryn Jackson, Adam Pah, Satyender Goel, Jorn Boehnke, John Eric Humphries, Scott Duke Kominers and et al.

Objective
To design and implement a tool that creates a secure, privacy preserving linkage of electronic health record (EHR) data across multiple sites in a large metropolitan area in the United States (Chicago, IL), for use in clinical... View Details

Keywords: Information; Customers; Safety; Rights; Ethics; Entrepreneurship; Health Care and Treatment; Health Industry; Chicago