Publications

June 1984
Case

Federal Trade Commission and the Shared Monopoly Case against the Ready-to-Eat Cereal Manufacturers

By: Thomas K. McCraw and Richard S. Tedlow

Keywords: Business and Government Relations; Monopoly; Courts and Trials; Food and Beverage Industry; United States

2008
Article

Entrepreneurial Ventures and Whole-body Donations: A Regional Perspective from the United States

By: Michel Anteby and Mikell Hyman

Human cadavers are crucial to medical science. While the debate on how to secure sufficient cadavers has focused primarily on donors' behaviors, procuring organizations' roles in increasing donations remain less explored. The United States offers a unique setting in... View Details

Keywords: Entrepreneurship; Behavior; Programs; Nonprofit Organizations; Business Ventures; Health Testing and Trials; Demand and Consumers; Supply Chain; For-Profit Firms; Organizations; Training; United States

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April 2017
Article

The New Look of Deal Protection

By: Guhan Subramanian and Fernán Restrepo

Deal protection in mergers and acquisitions (M&A) evolves in response to Delaware case law and the business goals of acquirers and targets. We construct a new sample of M&A deals from 2003 to 2015 to identify four such areas of evolution in current transactional... View Details

Keywords: Mergers and Acquisitions; Practice

11 Nov 2015
Working Paper Summaries

Public R&D Investments and Private-sector Patenting: Evidence from NIH Funding Rules

Keywords: by Danielle Li; Health; Biotechnology; Pharmaceutical; Medical Devices & Supplies

2012
Other Unpublished Work

Lost in the Clouds: The Impact of Copyright Scope on Investment in Cloud Computing Ventures

By: Josh Lerner and Greg Rafert

Our analysis seeks to understand the impact of changes in copyright scope on investment in new firms. We begin by analyzing the investment effects of the Cartoon Network, et al. v. Cablevision decision in the U.S. and court rulings in France and Germany on venture... View Details

Keywords: Technological Innovation; Venture Capital; Internet and the Web; Investment; Business Startups; Copyright; France; Germany; United States; European Union

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31 Jan 2020
Video

Blavatnik Fellow Jayon Wang Propelling X-COR Therapeutics Forward

Video

Jessica Clarke presents "The Right to Nonbinary Gender?"

20 Feb 2013
Research & Ideas

Big Deal: Reflections on the Megamerger of American and US Airways

selling assets, generating additional cash for the company and giving it more flexibility to restructure its operations. Under Section 363 of the Bankruptcy Code, assets can be sold by a court order, without... View Details

Keywords: Re: Rosabeth M. Kanter & Stuart C. Gilson; Air Transportation

Web

Rare Disease Day – Small Numbers, Big Challenges… and Big Opportunities - Blog: Health Supplement

Delivery Clinical Trials Health Care Innovation Public Health Hereditary Hemorrhagic Telangiectasia (HHT) . Not only a mouthful, but also very hard to spell and remember - a fitting name for a rare disease.... View Details

2021
Working Paper

Venture Capital's 'Me Too' Moment

By: Sophie Calder-Wang, Paul A. Gompers and Patrick Sweeney

In this paper, we document the historically low rate of hiring of women in the venture capital sector. We find that the high-profile Ellen Pao v. Kleiner Perkins gender discrimination trial had dramatic treatment effects. In difference-in-differences regressions, we... View Details

Keywords: Gender Discrimination; Founders; Venture Capital; Selection and Staffing; Gender; Lawsuits and Litigation

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19 Apr 2018
Video

Nalagenetics Final Pitch New Venture Competition 2018 Business Track

April 2014 (Revised July 2015)
Case

Sanofi Pasteur: The Dengue Vaccine Dilemma

By: V. Kasturi Rangan, David E. Bloom, Vincent Dessain and Emilie Billaud

In 2012, Sanofi Pasteur was racing to develop a vaccine against dengue, a mosquito-borne disease, and was evaluating this product in a Phase IIb trial conducted with school children in Thailand. But while the candidate vaccine met the high safety expectations and a... View Details

Keywords: Health Testing and Trials; Product Launch; Market Entry and Exit; Emerging Markets; Pharmaceutical Industry; France

Web

Women, Work, and the “M” Word - Blog: Health Supplement

Blog Blog Health Care and Life Science at HBS Filter Results Arrow Down Arrow Up Read posts from Author Alumni Author Blavatnik Fellow Author Blavatnik Fellowship Team Author Executive Education Author HBS Partners Author HBS Staff Author... View Details

July 2005
Background Note

Guth v. Loft: Synopsis

By: Lynn S. Paine and Christopher Bruner

Provides a brief overview of the Supreme Court of Delaware's opinion in the 1939 case of Guth v. Loft, a widely cited application of the "corporate opportunity doctrine." Explores the corporate law principles regulating when a corporate manager can or cannot take... View Details

Keywords: Courts and Trials; Lawfulness; Management; Opportunities

November 2009 (Revised March 2010)
Case

Managing Drugs on the Forefront of Personalized Medicine: The Erbitux and Vectibix Story

By: Richard G. Hamermesh, Raju Kucherlapati and Rachel Gordon

In May 2007, Amgen Inc. (Amgen) received disappointing news from the European Medicines Agency (EMEA) that its drug Vectibix, developed to fight metastatic colorectal cancer, had been rejected. This was especially surprising news given that a similar rival drug had... View Details

Keywords: Entrepreneurship; Governing Rules, Regulations, and Reforms; Health Testing and Trials; Marketing Strategy; Product Positioning; Genetics; Biotechnology Industry; Europe; United States

January–February 2023
Article

Data-Driven COVID-19 Vaccine Development for Janssen

By: Dimitris Bertsimas, Michael Lingzhi Li, Xinggang Liu, Jennings Xu and Najat Khan

The COVID-19 pandemic has spurred extensive vaccine research worldwide. One crucial part of vaccine development is the phase III clinical trial that assesses the vaccine for safety and efficacy in the prevention of COVID-19. In this work, we enumerate the first... View Details

Keywords: COVID-19; Health Testing and Trials; Forecasting and Prediction; AI and Machine Learning; Research; Pharmaceutical Industry

July 2006 (Revised July 2007)
Case

C.K. Coolidge, Inc. (Abridged)

Coolidge (CKC), a chemical manufacturer, is being sued for patent infringement. The plaintiffs are the patent holder and its sole licensee, who is also a CKC competitor. An analyst at CKC has done a breakeven decision analysis from CKC's perspective, balancing going to... View Details

Keywords: Negotiation Preparation; Courts and Trials; Patents; Analysis; Decision Choices and Conditions; Lawsuits and Litigation; Chemical Industry