Publications

March 2024
Case

Biomanufacturing Decentralization by Stämm

By: Paul A. Gompers, Jenyfeer Martínez Buitrago and Mariana Cal

In Buenos Aires, Argentina, cousins Llamazares and D’Alvia founded Stämm, a startup based on the idea of decentralizing biomanufacturing processes and downsizing biotech facilities. After raising its seed and series A rounds, and while finalizing its series B round in... View Details

Keywords: Business Model; Business Startups; Entrepreneurship; Venture Capital; Selection and Staffing; Technological Innovation; Science-Based Business; Business Strategy; Commercialization; Growth and Development Strategy; Product Launch; Research and Development; Biotechnology Industry; Latin America; South America; Argentina; Buenos Aires

October 2023 (Revised May 2024)
Case

Thermo Fisher Scientific: Foray into Contract Research

By: Satish Tadikonda, William Marks and Kevin Emancipator

After publicly declaring that they would not enter the contract research organization (CRO) business in 2017, Thermo Fisher purchased Pharmaceutical Product Development (PPD), one of the biggest players in the CRO space, in 2021. Much had changed in the intervening... View Details

Keywords: Mergers and Acquisitions; Customer Focus and Relationships; Corporate Strategy; Organizational Change and Adaptation; Biotechnology Industry

November 2016 (Revised December 2016)
Supplement

Anthony Starks at InSiL Therapeutics (B)

By: Vicki Sato and Gary Pisano

This case accompanies the (A) case from Anthony Starks's perspective. View Details

Keywords: Biotech; Management Challenges; R＆D; R＆D Project Management; Management; Biotechnology Industry; California

October 2011
Case

Gene Sequencing: Staking a Position in an Expanding Industry

By: Richard G. Hamermesh, Mara Aspinall and Phillip Andrews

Towards the end of 2010, companies in the gene sequencing industry were pushing aggressive R&D programs to develop technologies and products in the race to sequence the entire human genome at a cost of $1,000. It remained to be seen when the "$1,000 genome" would... View Details

Keywords: Genetics; Business Growth and Maturation; Business Plan; Competition; Venture Capital; Biotechnology Industry

Find at Harvard

October 2009 (Revised January 2014)
Teaching Note

Sustainability at Millipore (TN)

By: Michael W. Toffel

Teaching Note for [610012]. View Details

Keywords: Environmental Sustainability; Organizational Structure; Investment; Projects; Performance Improvement; Framework; Measurement and Metrics; Corporate Disclosure; Biotechnology Industry

September 2008 (Revised April 2009)
Supplement

Kevin Sharer at Amgen: Sustaining the High-Growth Company (B)

By: William W. George

Kevin Sharer, CEO of Amgen, is assessing the challenges he has faced as a major product came under regulatory scrutiny. View Details

Keywords: Governing Rules, Regulations, and Reforms; Leadership; Product Development; Biotechnology Industry

2009
Working Paper

Social Influence Given (Partially) Deliberate Matching: Career Imprints in the Creation of Academic Entrepreneurs

By: Pierre Azoulay, Christopher C. Liu and Toby E. Stuart

Actors often match with associates on a small set of dimensions that matter most for the particular relationship at hand. In so doing, they are exposed to unanticipated social influences because counterparts have more interests, attitudes, and preferences than would-be... View Details

Keywords: Entrepreneurship; Patents; Marketplace Matching; Mathematical Methods; Science-Based Business; Power and Influence; Social and Collaborative Networks; Biotechnology Industry

Read Now

September 2003 (Revised March 2007)
Case

Direvo Biotech AG

Describes the financing and growth decisions facing Direvo, a young German biotech firm with a customer/partner that wants to become an investor. Also discusses the business model for Direvo's directed evolution technology, with applications in both industrial enzymes... View Details

Keywords: Business Model; Decisions; Business Exit or Shutdown; Value; Business Startups; Biotechnology Industry; Germany

April 2002
Teaching Note

Anagene, Inc. TN

By: Robert S. Kaplan

Teaching Note for (9-102-030). View Details

Keywords: Entrepreneurship; Public Ownership; Sales; Production; Forecasting and Prediction; Volume; Governing and Advisory Boards; Cost Accounting; Business or Company Management; Financial Reporting; Strategy; Performance Capacity; Biotechnology Industry

October 2001 (Revised March 2002)
Case

Perlegen Sciences

By: Linda A. Hill and Nicole Tempest

As a biotech start-up company involved in studying human genomes, Perlegen needed to develop an organization that fostered innovation and teamwork among a group of highly trained professionals from both the science and technology fields. Perlegen's CEO, Brad Margus,... View Details

Keywords: Innovation Leadership; Groups and Teams; Management Teams; Problems and Challenges; Business Startups; Genetics; Talent and Talent Management; Innovation Strategy; Biotechnology Industry