Filter Results:
(289)
Show Results For
- All HBS Web
(393)
- News (50)
- Research (289)
- Events (1)
- Multimedia (2)
- Faculty Publications (138)
Show Results For
- All HBS Web
(393)
- News (50)
- Research (289)
- Events (1)
- Multimedia (2)
- Faculty Publications (138)
Sort by
- Article
Use of Crowd Innovation to Develop an Artificial Intelligence-Based Solution for Radiation Therapy Targeting
By: Raymond H. Mak, Michael G. Endres, Jin Hyun Paik, Rinat A. Sergeev, Hugo Aerts, Christopher L. Williams, Karim R. Lakhani and Eva C. Guinan
Importance: Radiation therapy (RT) is a critical cancer treatment, but the existing radiation oncologist work force does not meet growing global demand. One key physician task in RT planning involves tumor segmentation for targeting, which requires substantial... View Details
Keywords: Crowdsourcing; AI Algorithms; Health Care and Treatment; Collaborative Innovation and Invention; AI and Machine Learning
Mak, Raymond H., Michael G. Endres, Jin Hyun Paik, Rinat A. Sergeev, Hugo Aerts, Christopher L. Williams, Karim R. Lakhani, and Eva C. Guinan. "Use of Crowd Innovation to Develop an Artificial Intelligence-Based Solution for Radiation Therapy Targeting." JAMA Oncology 5, no. 5 (May 2019): 654–661.
- 12 Oct 2011
- First Look
First Look: October 12
Michael Schwarz Abstract We consider market rules for the transfer of IP addresses, numeric identifiers required by all computers connected to the Internet. Excessive fragmentation of IP address blocks causes growth in the Internet's... View Details
Keywords: Sean Silverthorne
- 02 Jun 2010
- First Look
First Look: June 2
Ert, and Alvin E. Roth Publication:Special Issue on Predicting Behavior in Games. Games 1, no. 2 (2010) An abstract is unavailable at this time. Read the paper: http://www.mdpi.com/2073-4336/1/2/117/ The Counterfeit Self: The Deceptive Costs of Faking It... View Details
Keywords: Martha Lagace
- 21 Feb 2017
- First Look
First Look at New Research: February 21
Publisher's link: https://www.hbs.edu/faculty/Pages/item.aspx?num=52291 Platforms, Open/User Innovation, and Ecosystems: A Strategic Leadership Perspective By: Altman, Elizabeth J., and Michael L. Tushman Abstract—Platform, open/user... View Details
Keywords: Carmen Nobel
- 20 Dec 2016
- First Look
December 20, 2016
forthcoming Research in Organizational Behavior The Dynamic Componential Model of Creativity and Innovation in Organizations: Making Progress, Making Meaning By: Amabile, Teresa M., and Michael G. Pratt... View Details
Keywords: Carmen Nobel
- 10 Apr 2012
- First Look
First Look: April 10
patterns with the calorie labeling present. These findings highlight the potential importance of portion control interventions that specifically activate consumers' self-control. Environmental Federalism in the European Union and the United States Authors:David Vogel,... View Details
Keywords: Carmen Nobel
- 30 Jun 2009
- First Look
First Look: June 30
Working PapersWellsprings of Creation: How Perturbation Sustains Exploration in Mature Organizations (revised) Authors:David James Brunner, Bradley R. Staats, Michael L. Tushman, and David M. Upton Abstract Organizations struggle to... View Details
Keywords: Martha Lagace
- 04 Dec 2012
- First Look
First Look: December 4
Homophily and Structure in a Formal Organization Authors:Adam M. Kleinbaum, Toby E. Stuart, and Michael Tushman Publication:Organization Science Abstract Homophily in social relations results from both individual preferences and selective... View Details
Keywords: Carmen Nobel
- 02 Apr 2019
- First Look
New Research and Ideas, April 2, 2019
Frame Flexibility: The Role of Cognitive and Emotional Framing in Innovation Adoption by Incumbent Firms By: Raffaelli, Ryan, Mary Ann Glynn, and Michael Tushman Abstract—Why do incumbent firms frequently reject nonincremental... View Details
Keywords: Dina Gerdeman
- 10 May 2016
- First Look
May 10, 2016
Promises and Limitations of Improved Measures of Urban Life By: Glaeser, Edward L., Scott Duke Kominers, Michael Luca, and Nikhil Naik Abstract—New, "big" data sources allow measurement of city characteristics and outcome... View Details
Keywords: Carmen Nobel
- 19 Jan 2016
- First Look
January 19, 2016
Patient Outcomes in Cardiac Surgery By: Burt, Bryan M., Andrew W. ElBardissi, Robert S. Huckman, Lawrence H. Cohn, Marisa W. Cevasco, James D. Rawn, Sary F. Aranki, and John G. Byrne Abstract—We hypothesized that increased post-graduate... View Details
Keywords: Sean Silverthorne
- Article
Advancing Computational Biology and Bioinformatics Research Through Open Innovation Competitions
By: Andrea Blasco, Michael G. Endres, Rinat A. Sergeev, Anup Jonchhe, Max Macaluso, Rajiv Narayan, Ted Natoli, Jin H. Paik, Bryan Briney, Chunlei Wu, Andrew I. Su, Aravind Subramanian and Karim R. Lakhani
Open data science and algorithm development competitions offer a unique avenue for rapid discovery of better computational strategies. We highlight three examples in computational biology and bioinformatics research where the use of competitions has yielded significant... View Details
Keywords: Computational Biology; Bioinformatics; Innovation Competitions; Research; Collaborative Innovation and Invention
Blasco, Andrea, Michael G. Endres, Rinat A. Sergeev, Anup Jonchhe, Max Macaluso, Rajiv Narayan, Ted Natoli, Jin H. Paik, Bryan Briney, Chunlei Wu, Andrew I. Su, Aravind Subramanian, and Karim R. Lakhani. "Advancing Computational Biology and Bioinformatics Research Through Open Innovation Competitions." PLoS ONE 14, no. 9 (September 2019).
- 06 Mar 2012
- First Look
First Look: March 6
and Michael W. Toffel Abstract Mandatory information disclosure regulations seek to create institutional pressure to spur performance improvement. By examining how organizational characteristics moderate facilities' responses to a... View Details
Keywords: Sean Silverthorne
- 28 Aug 2018
- First Look
New Research and Ideas, August 28, 2018
https://www.hbs.edu/faculty/Pages/item.aspx?num=54899 forthcoming Management Science How Do Sales Efforts Pay Off? Dynamic Panel Data Analysis in the Nerlove-Arrow Framework By: Chung, Doug J., Byungyeon Kim, and Byoung G. Park Abstract—... View Details
Keywords: Dina Gerdeman
- March 12, 2009
- Article
A Nonsimultaneous, Extended, Altruistic-Donor Chain
By: Michael A. Rees, Jonathan E. Kopke, Ronald P. Pelletier, Dorry L. Segev, Matthew E. Rutter, Alfredo J. Fabrega, Jeffrey Rogers, Oleh G. Pankewycz, Janet Hiller, Alvin E. Roth, Tuomas Sandholm, Utku Unver and Robert A. Montgomery
Rees, Michael A., Jonathan E. Kopke, Ronald P. Pelletier, Dorry L. Segev, Matthew E. Rutter, Alfredo J. Fabrega, Jeffrey Rogers, Oleh G. Pankewycz, Janet Hiller, Alvin E. Roth, Tuomas Sandholm, Utku Unver, and Robert A. Montgomery. "A Nonsimultaneous, Extended, Altruistic-Donor Chain." New England Journal of Medicine 360, no. 11 (March 12, 2009): 1096–1101.
- September 15, 2021
- Article
Improving Deconvolution Methods in Biology Through Open Innovation Competitions: An Application to the Connectivity Map
By: Andrea Blasco, Ted Natoli, Michael G. Endres, Rinat A. Sergeev, Steven Randazzo, Jin Hyun Paik, N.J. Maximilian Macaluso, Rajiv Narayan, Xiaodong Lu, David Peck, Karim R. Lakhani and Aravind Subramanian
A recurring problem in biomedical research is how to isolate signals of distinct populations (cell types, tissues, and genes) from composite measures obtained by a single analyte or sensor. Existing computational deconvolution approaches work well in many specific... View Details
Keywords: Deconvolution; Methods; Open Innovation Competition; Genomics; Research; Innovation and Invention
Blasco, Andrea, Ted Natoli, Michael G. Endres, Rinat A. Sergeev, Steven Randazzo, Jin Hyun Paik, N.J. Maximilian Macaluso, Rajiv Narayan, Xiaodong Lu, David Peck, Karim R. Lakhani, and Aravind Subramanian. "Improving Deconvolution Methods in Biology Through Open Innovation Competitions: An Application to the Connectivity Map." Bioinformatics 37, no. 18 (September 15, 2021).
- April 2009
- Journal Article
Perspectives on the Productivity Dilemma
By: Paul S. Adler, Mary Benner, David James Brunner, John Paul MacDuffie, Emi Osono, Bradley R. Staats, Hirotaka Takeuchi, Michael Tushman and Sidney G. Winter
For more than a century, operations researchers have recognized that organizations can increase efficiency by adhering strictly to proven process templates, thereby rendering operations more stable and predictable. For several decades, researchers have also recognized... View Details
Keywords: Learning; Innovation and Invention; Knowledge Use and Leverage; Operations; Business Processes; Organizational Change and Adaptation; Performance Efficiency; Performance Improvement; Performance Productivity; Adaptation
Adler, Paul S., Mary Benner, David James Brunner, John Paul MacDuffie, Emi Osono, Bradley R. Staats, Hirotaka Takeuchi, Michael Tushman, and Sidney G. Winter. "Perspectives on the Productivity Dilemma." Journal of Operations Management 27, no. 2 (April 2009): 99–113.
- 19 Jan 2011
- First Look
First Look: Jan. 18
In this article, Pozen presents a new model for the corporate board. Read the article: http://hbr.org/2010/12/the-big-idea-the-case-for-professional-boards/ar/1# M@n@gement in Times of Economic Crisis: Insights into Organizational Ambidexterity Authors:Achim Schmitt,... View Details
Keywords: Sean Silverthorne
- Article
Development of a Deep Learning Algorithm for Periapical Disease Detection in Dental Radiographs
By: Michael G. Endres, Florian Hillen, Marios Salloumis, Ahmad R. Sedaghat, Stefan M. Niehues, Olivia Quatela, Henning Hanken, Ralf Smeets, Benedicta Beck-Broichsitter, Carsten Rendenbach, Karim R. Lakhani, Max Helland and Robert A. Gaudin
Periapical radiolucencies, which can be detected on panoramic radiographs, are one of the most common radiographic findings in dentistry and have a differential diagnosis including infections, granuloma, cysts, and tumors. In this study, we seek to investigate the... View Details
Keywords: Artificial Intelligence; Diagnosis; Computer-assisted; Image Interpretation; Machine Learning; Radiography; Panoramic Radiograph; AI and Machine Learning
Endres, Michael G., Florian Hillen, Marios Salloumis, Ahmad R. Sedaghat, Stefan M. Niehues, Olivia Quatela, Henning Hanken, Ralf Smeets, Benedicta Beck-Broichsitter, Carsten Rendenbach, Karim R. Lakhani, Max Helland, and Robert A. Gaudin. "Development of a Deep Learning Algorithm for Periapical Disease Detection in Dental Radiographs." Diagnostics 10, no. 6 (June 2020).
- October 2019
- Article
Adaptive Platform Trials: Definition, Design, Conduct and Reporting Considerations
By: Derek C. Angus, Brian M. Alexander, Scott Berry, Meredith Buxton, Roger Lewis, Melissa Paoloni, Steven A. R. Webb, Steven Arnold, Anna Barker, Donald A. Berry, Marc J. M. Bonten, Mary Brophy, Christopher Butler, Timothy F. Cloughesy, Lennie P. G. Derde, Laura J. Esserman, Ryan Ferguson, Louis Fiore, Sarah C. Gaffey, J. Michael Gaziano, Kathy Giusti, Herman Goossens, Stephane Heritier, Bradley Hyman, Michael Krams, Kay Larholt, Lisa M. LaVange, Philip Lavori, Andrew W. Lo, Alexander J. London, Victoria Manax, Colin McArthur, Genevieve O’Neill, Giovanni Parmigiani, Jane Perlmutter, Elizabeth A. Petzold, Craig Ritchie, Kathryn M. Rowan, Christopher W. Seymour, Nathan I. Shapiro, Diane M. Simeone, Bradley Smith, Bradley Spellberg, Ariel Dora Stern, Lorenzo Trippa, Mark Trusheim, Kert Viele, Patrick Y. Wen and Janet Woodcock
Researchers, clinicians, policymakers, and patients are increasingly interested in questions about therapeutic interventions that are difficult or costly to answer with traditional, free-standing, parallel-group randomized controlled trials (RCTs). Examples include... View Details
Angus, Derek C., Brian M. Alexander, Scott Berry, Meredith Buxton, Roger Lewis, Melissa Paoloni, Steven A. R. Webb, Steven Arnold, Anna Barker, Donald A. Berry, Marc J. M. Bonten, Mary Brophy, Christopher Butler, Timothy F. Cloughesy, Lennie P. G. Derde, Laura J. Esserman, Ryan Ferguson, Louis Fiore, Sarah C. Gaffey, J. Michael Gaziano, Kathy Giusti, Herman Goossens, Stephane Heritier, Bradley Hyman, Michael Krams, Kay Larholt, Lisa M. LaVange, Philip Lavori, Andrew W. Lo, Alexander J. London, Victoria Manax, Colin McArthur, Genevieve O’Neill, Giovanni Parmigiani, Jane Perlmutter, Elizabeth A. Petzold, Craig Ritchie, Kathryn M. Rowan, Christopher W. Seymour, Nathan I. Shapiro, Diane M. Simeone, Bradley Smith, Bradley Spellberg, Ariel Dora Stern, Lorenzo Trippa, Mark Trusheim, Kert Viele, Patrick Y. Wen, and Janet Woodcock. "Adaptive Platform Trials: Definition, Design, Conduct and Reporting Considerations." Nature Reviews: Drug Discovery 18, no. 10 (October 2019): 797–807.