Publications

March 2002 (Revised May 2002)
Case

Genzyme: Engineering the Market for Orphan Drugs

Genzyme has made money with external technology in orphan drug markets generally considered to be too small to be attractive to other drug companies. Now competition is entering these same markets, placing Genzyme's business model under new pressures. View Details

Keywords: Business Model; Information Technology; Market Entry and Exit; Biotechnology Industry; Biotechnology Industry

September 2001
Supplement

Millennium Pharmaceuticals, Inc. (B)

By: Stefan H. Thomke and Ashok Nimgade

Supplements the (A) case. View Details

Keywords: Pharmaceutical Industry; Pharmaceutical Industry; Cambridge

October 2000
Teaching Note

Kendle International Inc. TN

By: Dwight B. Crane and Indra Reinbergs

Teaching Note for (9-200-033). View Details

Keywords: Biotechnology Industry; Biotechnology Industry

September 1997
Case

Bayer AG (B)

By: John A. Quelch

Bayer's senior executives detail the communications challenge program that resulted from the company's reacquisition of its brand name and trademark cross, which gave Bayer one name worldwide for the first time since World War I. View Details

Keywords: Globalized Firms and Management; War; Acquisition; Trademarks; Brands and Branding; Communication Strategy; Biotechnology Industry; Biotechnology Industry; Germany

2000
Chapter

In Search of Dynamic Capabilities: The Origins of R&D Competence in Biopharmaceuticals

By: Gary P. Pisano

Keywords: Competency and Skills; Research and Development; Pharmaceutical Industry; Pharmaceutical Industry

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10 Aug 2020
Research & Ideas

COVID's Surprising Toll on Careers of Women Scientists

Foundation. About the Author Rachel Layne is a writer based in the Boston area. [Image: valentinrussanov] Related Reading Restaurant Revolution: How the Industry Is Fighting to Stay Alive Who Guarantees Your Workplace Is Safe for Return?... View Details

Keywords: by Rachel Layne; Biotechnology; Biotechnology; Biotechnology

May 1999
Teaching Note

Genset: 1989 TN

By: Paul A. Gompers

Teaching Note for (9-298-070). View Details

Keywords: Biotechnology Industry; France

January 2025
Case

Moderna: Democratizing Artificial Intelligence

By: Iavor I. Bojinov, Karim R. Lakhani, Annika Hildebrandt and James Weber

The case study examines Moderna's journey in democratizing artificial intelligence (AI), particularly generative AI, across its workforce. It details the company's "digital-first, AI-focused" approach, including the rollout of OpenAI's ChatGPT Enterprise to all... View Details

Keywords: AI and Machine Learning; Technology Adoption; Innovation Strategy; Governance Controls; Biotechnology Industry

March 2020 (Revised June 2020)
Case

Social Salary Setting at Spiber

By: Ashley Whillans and John Beshears

Can a “set your own salary” system boost employee happiness and motivation? Spiber made synthetic silk built from proteins mimicking the proteins found in spider silk, the world’s toughest known material by weight. Kazuhide Sekiyama and Junichi Sugahara established... View Details

Keywords: Compensation and Benefits; Motivation and Incentives; Happiness; Negotiation Tactics; Cross-Cultural and Cross-Border Issues; Biotechnology Industry; Japan; United States

September 2019 (Revised August 2020)
Case

Engineering an Inclusive Bioeconomy

By: Tarun Khanna, Raffaella Sadun and Susie L. Ma

In 2019, entrepreneur Juan Carlos Castilla-Rubio was developing a project he hoped could generate and share wealth from the natural resources of the Amazon without destroying those resources. His idea, called Earth Bank of Codes (EBC), would create a library of the... View Details

September 2011
Teaching Note

Tengion: Bringing Regenerative Medicine to Life (TN)

By: Elie Ofek and Natalie Kindred

Teaching Note for 510031. View Details

Keywords: Partners and Partnerships; Production; Marketing; Cash; Health Care and Treatment; Medical Specialties; Research and Development; Biotechnology Industry

September 2009
Teaching Note

iZumi (TN)

By: Robert F. Higgins

Teaching Note for [809105]. View Details

Keywords: Perspective; Intellectual Property; Venture Capital; Innovation and Invention; Investment; Financing and Loans; Information Technology; Mergers and Acquisitions; Commercialization; Biotechnology Industry

December 2004 (Revised July 2005)
Case

Extend Fertility

By: Myra M. Hart and Sylvia Sensiper

Focuses on the search for opportunity, the generation and evaluation of business concepts, creation of a business plan, and the start-up process. Follows experienced entrepreneur Christy Jones as she combines her business skills and personal experience to generate new... View Details

Keywords: Opportunities; Business Plan; Entrepreneurship; Personal Development and Career; Social Issues; Gender; Business Startups; Biotechnology Industry

June 2003 (Revised October 2003)
Case

Institut Pasteur

The Pasteur Institut is implementing a proactive commercialization strategy under the direction of Christian Policard. Highlights the government's innovation policy and the role that the Pasteur Institut can play in shaping it. Also addresses issues relating to higher... View Details

Keywords: Commercialization; Research and Development; Biotechnology Industry; France

October 2001 (Revised March 2008)
Case

Anagene, Inc.

By: Robert S. Kaplan and Christina L. Darwall

An entrepreneurial, publicly traded biotech company has begun production and sales of its core product--cartridges that permit DNA samples to be analyzed on a microchip. In the early quarters, sales are difficult to forecast and the company has experienced fluctuating... View Details

Keywords: Cost Accounting; Financial Reporting; Production; Performance Capacity; Risk and Uncertainty; Genetics; Governing and Advisory Boards; Biotechnology Industry; California

February 1994
Case

Alpha-Beta Technology, Inc.: Pioneering Carbohydrate Technology

Alpha-Beta was founded in 1988 by two scientist-entrepreneurs with ten patents on carbohydrate technology. In 1991, the company faces critical questions about how to focus its product definition from among several promising, but risky, choices. How should they analyze... View Details

Keywords: Technological Innovation; Product Design; Entrepreneurship; Product Development; Biotechnology Industry

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November 1978 (Revised October 1989)
Case

Amicon Corp. (A)

Amicon holds a patent on a new process for the separation of blood plasma from whole blood. It has to decide whether to pursue a direct entry, joint venture, or licensing strategy. If it chooses licensing, there are many sub-issues to consider. View Details

Keywords: Technology; Patents; Commercialization; Health Care and Treatment; Biotechnology Industry

October 1987
Case

T Cell Sciences, Inc.

By: Francis Aguilar

Keywords: Biotechnology Industry