Publications

January 2025
Case

Moderna: Democratizing Artificial Intelligence

By: Iavor I. Bojinov, Karim R. Lakhani, Annika Hildebrandt and James Weber

The case study examines Moderna's journey in democratizing artificial intelligence (AI), particularly generative AI, across its workforce. It details the company's "digital-first, AI-focused" approach, including the rollout of OpenAI's ChatGPT Enterprise to all... View Details

Keywords: AI and Machine Learning; Technology Adoption; Innovation Strategy; Governance Controls; Biotechnology Industry

March 2020 (Revised June 2020)
Case

Social Salary Setting at Spiber

By: Ashley Whillans and John Beshears

Can a “set your own salary” system boost employee happiness and motivation? Spiber made synthetic silk built from proteins mimicking the proteins found in spider silk, the world’s toughest known material by weight. Kazuhide Sekiyama and Junichi Sugahara established... View Details

Keywords: Compensation and Benefits; Motivation and Incentives; Happiness; Negotiation Tactics; Cross-Cultural and Cross-Border Issues; Biotechnology Industry; Japan; United States

September 2019 (Revised August 2020)
Case

Engineering an Inclusive Bioeconomy

By: Tarun Khanna, Raffaella Sadun and Susie L. Ma

In 2019, entrepreneur Juan Carlos Castilla-Rubio was developing a project he hoped could generate and share wealth from the natural resources of the Amazon without destroying those resources. His idea, called Earth Bank of Codes (EBC), would create a library of the... View Details

September 2011
Teaching Note

Tengion: Bringing Regenerative Medicine to Life (TN)

By: Elie Ofek and Natalie Kindred

Teaching Note for 510031. View Details

Keywords: Partners and Partnerships; Production; Marketing; Cash; Health Care and Treatment; Medical Specialties; Research and Development; Biotechnology Industry

September 2009
Teaching Note

iZumi (TN)

By: Robert F. Higgins

Teaching Note for [809105]. View Details

Keywords: Perspective; Intellectual Property; Venture Capital; Innovation and Invention; Investment; Financing and Loans; Information Technology; Mergers and Acquisitions; Commercialization; Biotechnology Industry

December 2004 (Revised July 2005)
Case

Extend Fertility

By: Myra M. Hart and Sylvia Sensiper

Focuses on the search for opportunity, the generation and evaluation of business concepts, creation of a business plan, and the start-up process. Follows experienced entrepreneur Christy Jones as she combines her business skills and personal experience to generate new... View Details

Keywords: Opportunities; Business Plan; Entrepreneurship; Personal Development and Career; Social Issues; Gender; Business Startups; Biotechnology Industry

June 2003 (Revised October 2003)
Case

Institut Pasteur

The Pasteur Institut is implementing a proactive commercialization strategy under the direction of Christian Policard. Highlights the government's innovation policy and the role that the Pasteur Institut can play in shaping it. Also addresses issues relating to higher... View Details

Keywords: Commercialization; Research and Development; Biotechnology Industry; France

October 2001 (Revised March 2008)
Case

Anagene, Inc.

By: Robert S. Kaplan and Christina L. Darwall

An entrepreneurial, publicly traded biotech company has begun production and sales of its core product--cartridges that permit DNA samples to be analyzed on a microchip. In the early quarters, sales are difficult to forecast and the company has experienced fluctuating... View Details

Keywords: Cost Accounting; Financial Reporting; Production; Performance Capacity; Risk and Uncertainty; Genetics; Governing and Advisory Boards; Biotechnology Industry; California

February 1994
Case

Alpha-Beta Technology, Inc.: Pioneering Carbohydrate Technology

Alpha-Beta was founded in 1988 by two scientist-entrepreneurs with ten patents on carbohydrate technology. In 1991, the company faces critical questions about how to focus its product definition from among several promising, but risky, choices. How should they analyze... View Details

Keywords: Technological Innovation; Product Design; Entrepreneurship; Product Development; Biotechnology Industry

Find at Harvard

November 1978 (Revised October 1989)
Case

Amicon Corp. (A)

Amicon holds a patent on a new process for the separation of blood plasma from whole blood. It has to decide whether to pursue a direct entry, joint venture, or licensing strategy. If it chooses licensing, there are many sub-issues to consider. View Details

Keywords: Technology; Patents; Commercialization; Health Care and Treatment; Biotechnology Industry

October 1987
Case

T Cell Sciences, Inc.

By: Francis Aguilar

Keywords: Biotechnology Industry

Find at Harvard

October 2009 (Revised January 2014)
Teaching Note

Sustainability at Millipore (TN)

By: Michael W. Toffel

Teaching Note for [610012]. View Details

Keywords: Environmental Sustainability; Organizational Structure; Investment; Projects; Performance Improvement; Framework; Measurement and Metrics; Corporate Disclosure; Biotechnology Industry

01 Dec 1996
News

Entrepreneurship at HBS

direct marketing, consumer products, and consulting. Following Professor Georges F. Doriot's lead, our graduates have had a major impact on the venture capital industry, which in turn financed a revolution in semiconductors, personal computers, communications, and... View Details

17 Oct 2012
Research & Ideas

America Needs a Manufacturing Renaissance

Erosion Of The Industrial Commons From, Producing Prosperity: Why America Needs a Manufacturing Renaissance By Gary P. Pisano and Willy C. Shih In times past, farmers and local townspeople would bring their livestock to the commons—a... View Details

Keywords: by Gary P. Pisano & Willy C. Shih; Manufacturing

20 Sep 2021
Blog Post

Student Spotlight: Summer Internships in Business and Environment

durations, and dispatch it as electricity on demand. Cal's role prior to HBS was an Aerospace Industry Application Engineer at Mathworks. Aditya Desai (MBA 2022, Section J), Summer Internship: MBA Summer Intern at Natron Energy Natron... View Details

02 Feb 2021
Blog Post

Finding My Focus in Health care Amidst a Global Pandemic

biotechnology and health-tech companies. After about a year and a half, I went to work at one of JPM’s clients to build their Growth Strategy team. After an interesting first several months, I found myself testifying as a whistleblower to... View Details

10 Aug 2020
Research & Ideas

COVID's Surprising Toll on Careers of Women Scientists

Foundation. About the Author Rachel Layne is a writer based in the Boston area. [Image: valentinrussanov] Related Reading Restaurant Revolution: How the Industry Is Fighting to Stay Alive Who Guarantees Your Workplace Is Safe for Return?... View Details

Keywords: by Rachel Layne; Biotechnology; Biotechnology; Biotechnology

July 1993
Case

Genzyme Corporation: A Financing History

By: Timothy A. Luehrman and Andrew D. Regan

Genzyme Corp.'s financing history is unusual compared to most biotech companies. This case presents the sequence of financings employed by Genzyme, along with the product--market and corporate-development strategies adopted by Henri Termeer, Genzyme's CEO. As such, the... View Details

Keywords: History; Marketing Strategy; Financing and Loans; Business Strategy; Growth and Development Strategy; Biotechnology Industry

July 2023
Case

Moderna: Everything, Everywhere, All at Once

By: Satish Tadikonda, Shikhar Ghosh and William Marks

Coming out of the COVID-19 pandemic, Moderna was riding the successes of developing a vaccine in record time and helping stem the tide of the crisis. However, the company had grown at an incredible rate, more than doubled its number of employees, and had to put on hold... View Details

Keywords: Health Pandemics; Selection and Staffing; Growth Management; Management Succession; Retirement; Technological Innovation; Corporate Strategy; Biotechnology Industry