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  • November 2014
  • Teaching Note

Claritas Genomics

By: Robert F. Higgins and Matthew G. Preble
Dr. Patrice Milos is the first CEO of Claritas Genomics (Claritas) and she faces a number of challenges in scaling the young company. Claritas was formed around a lab spun out from Boston Children's Hospital (BCH) which had performed genomic tests for the hospital. Now... View Details
Keywords: Healthcare; Healthcare Startups; Genetic Testing; Genetics Diagnostics; Spinning Out Hospital Services; Spin-out; Health Care and Treatment; Genetics; Entrepreneurship; Biotechnology Industry; Health Industry; United States
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Higgins, Robert F., and Matthew G. Preble. "Claritas Genomics." Harvard Business School Teaching Note 815-032, November 2014.
  • January 2023 (Revised May 2023)
  • Case

Steve Jobs: Changing the World

By: Robert Simons and Shirley Sun
This case traces the life of Steve Jobs who throughout his career flaunted convention and chose an unusual path to success. The case describes how Jobs, as young man, acquired an appreciation for aesthetics and the liberal arts, but was also quick to recognize and... View Details
Keywords: Entrepreneurship; Technology; Business Startups; Personal Characteristics; Leadership Style; Innovation; Work-life Balance; Innovation Leadership; Power and Influence; Success; Information Technology Industry; United States
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Simons, Robert, and Shirley Sun. "Steve Jobs: Changing the World." Harvard Business School Case 123-022, January 2023. (Revised May 2023.)
  • October 2022
  • Case

Volt Lines: Leading a B2B Service Provider through a Crisis (A)

By: Navid Mojir and Gamze Yucaoglu
Volt Lines was a next-generation transportation service in Istanbul, Turkey. The company was trying to disrupt the traditional corporate transportation market by developing software that allowed it to offer subscription-based transportation. Under the subscription... View Details
Keywords: Business To Business Marketing; B2B Marketing; B2B Pricing; Subscription Model; Crisis Marketing; Startup; Service Management; Information Technology; Transportation; COVID-19 Pandemic; Disruptive Innovation; Digital Platforms; Business Model; Price; Crisis Management; Opportunities; Transportation Industry; Technology Industry; Turkey
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Mojir, Navid, and Gamze Yucaoglu. "Volt Lines: Leading a B2B Service Provider through a Crisis (A)." Harvard Business School Case 523-037, October 2022.
  • July 2019 (Revised November 2019)
  • Case

Osaro: Picking the Best Path

By: William R. Kerr, James Palano and Bastiane Huang
The founder of Osaro saw the potential of deep reinforcement learning to allow robots to be applied to new applications. Osaro targeted warehousing, already a dynamic industry for robotics and automation, for its initial product—a system which would allow robotic arms... View Details
Keywords: Artificial Intelligence; Machine Learning; Robotics; Robots; Ecommerce; Fulfillment; Warehousing; AI; Startup; Technology Commercialization; Business Startups; Entrepreneurship; Logistics; Order Taking and Fulfillment; Information Technology; Commercialization; Learning; Complexity; Competition; E-commerce
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Kerr, William R., James Palano, and Bastiane Huang. "Osaro: Picking the Best Path." Harvard Business School Case 820-012, July 2019. (Revised November 2019.)
  • Research Summary

Overview

I study how people collaborate with each other as they define, change, and solve problems while working on creativity and innovation projects in organizations.

Conference Proceedings:
Cromwell, J. & Gardner, H. 2017. High-stakes innovation: When... View Details
Keywords: Innovation; Innovation & Entrepreneurship; Startups; Decision Choice And Uncertainty; Teams; Team Process
  • November 2024
  • Supplement

AlphaGo (C): Birth of a New Intelligence

By: Shikhar Ghosh and Shweta Bagai
This case, the final of a three-part series, explores DeepMind's pivotal transition from mastering games to solving real-world scientific challenges. In December 2020, DeepMind's AI system AlphaFold 2 achieved a breakthrough by solving protein folding—a 50-year-old... View Details
Keywords: Autonomy; Deep Learning; Drug Discovery; Healthcare Innovation; Neural Networks; Scientific Research; Technology Startup; AI and Machine Learning; Technological Innovation; Research and Development; Business Model; Business Strategy; Open Source Distribution; Technology Industry; United States
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Ghosh, Shikhar, and Shweta Bagai. "AlphaGo (C): Birth of a New Intelligence." Harvard Business School Supplement 825-075, November 2024.
  • June 2018
  • Teaching Note

LabCDMX: Experiment 50

By: Mitchell Weiss and Matt Higgins
Teaching Note for HBS No. 817-031. View Details
Keywords: Public Entrepreneurship; Experimentation; Lean Startup; Government; Innovation; Crowdsourcing; Open Data; Mexico City; Mexico; Entrepreneurship; Innovation and Invention; Social Entrepreneurship; Government Administration; Transportation; Innovation Leadership; Transportation Industry; Public Administration Industry; Mexico; Mexico City
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Weiss, Mitchell, and Matt Higgins. "LabCDMX: Experiment 50." Harvard Business School Teaching Note 818-135, June 2018.
  • December 2014 (Revised November 2023)
  • Case

Codecademy: Monetizing a Movement?

By: Jeffrey J. Bussgang and Lisa C. Mazzanti
Codecademy, an open-platform, online community for learning computer programming, launched in 2011. By 2014, the company had raised a total of $12.5 million in funding and was, on many fronts, an overwhelming success. However, there were still no revenues. The founders... View Details
Keywords: Entrepreneurial Management; Startup Management; Technology; Computer Programming; Coding; Online Education; Monetization; Online Communities; Marketplaces; Internet and the Web; Education; Entrepreneurship; Business Startups; Growth and Development Strategy; Technology Industry; Education Industry
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Bussgang, Jeffrey J., and Lisa C. Mazzanti. "Codecademy: Monetizing a Movement?" Harvard Business School Case 815-093, December 2014. (Revised November 2023.)
  • September 2014 (Revised January 2017)
  • Teaching Note

Access Health CT: Marketing Affordable Care (A) & (B)

By: John A. Quelch
Keywords: Affordable Care Act (ACA); Marketing Communications; Market Segmentation; Marketing Management; Startup Management; Analysis; Innovation and Invention; Marketing; Measurement and Metrics; Outcome or Result; Performance; Strategy; Health Industry; Insurance Industry; North and Central America
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Quelch, John A. "Access Health CT: Marketing Affordable Care (A) & (B)." Harvard Business School Teaching Note 515-014, September 2014. (Revised January 2017.)
  • July 2020
  • Case

Kathy Fish at Procter & Gamble: Navigating Industry Disruption by Disrupting from Within

By: Emily Truelove, Linda A. Hill and Emily Tedards
When Kathy Fish, Procter & Gamble’s Chief Research, Development & Innovation Officer, and a 40-year company veteran, stepped into her role in 2014, she was concerned that the world’s leading consumer packaged goods company had lost its capability to produce a steady... View Details
Keywords: Female Protagonist; Organizational Change; Organizational Behavior; Culture Change; Digital; Innovation; Lean Startup; Experimentation; Metrics; Consumer Packaged Goods (CPG); Leadership; Leading Change; Change Management; Organizational Culture; Organizational Change and Adaptation; Disruption; Innovation and Invention; Digital Transformation
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Truelove, Emily, Linda A. Hill, and Emily Tedards. "Kathy Fish at Procter & Gamble: Navigating Industry Disruption by Disrupting from Within." Harvard Business School Case 421-012, July 2020.
  • February 2019 (Revised June 2019)
  • Case

Where to Grow Next at Online Marketplace OLX

By: Thales Teixeira, Leandro A. Guissoni and Samy Dana
The CEO of OLX Brazil, an online classifieds platform business, is debating among multiple paths to grow sustainably (i.e., profitably) without the need for investor money. The options under consideration are (1) penetration growth by focusing on the core, (2) new... View Details
Keywords: Online Marketplace; Growth; Customer Acquisition; Facebook; Two-sided Network; E-commerce; Classifieds; Naspers; Schibsted; Innovation; Startup; Digital Platforms; Internet and the Web; Growth and Development Strategy; Business Model; Innovation and Invention; Business Startups; Decision Choices and Conditions; Brazil
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Teixeira, Thales, Leandro A. Guissoni, and Samy Dana. "Where to Grow Next at Online Marketplace OLX." Harvard Business School Case 519-064, February 2019. (Revised June 2019.)
  • October 2019
  • Case

Leading Bank Leumi into the Future

By: Joshua D. Margolis, Allison M. Ciechanover, Nicole Keller and Danielle Golan
An unlikely but highly effective leader of a traditional bank, Rakefet Russak-Aminoach, simultaneously leads a classic change effort and an unconventional effort to innovate. She focuses her initial energy on making the bank more efficient in the face of industry... View Details
Keywords: Mobile Banking; Digital Banking; Fintech; Startup; Financial Services; Artificial Intelligence; Innovation; Efficiency; Organizational Change; Personal Development; Female Ceo; Banks and Banking; Mobile and Wireless Technology; Leadership; Organizational Change and Adaptation; Innovation and Invention; Disruption; Information Technology; Opportunities; Performance Effectiveness; Personal Development and Career; AI and Machine Learning; Financial Services Industry; Banking Industry; Israel
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Margolis, Joshua D., Allison M. Ciechanover, Nicole Keller, and Danielle Golan. "Leading Bank Leumi into the Future." Harvard Business School Case 420-063, October 2019.
  • March 2019
  • Case

DayTwo: Going to Market with Gut Microbiome

By: Ayelet Israeli and David Lane
DayTwo is a young Israeli startup that applies research on the gut microbiome and machine learning algorithms to deliver personalized nutritional recommendations to its users in order to minimize blood sugar spikes after meals. After a first year of trial rollout in... View Details
Keywords: Start-up Growth; Startup; Positioning; Targeting; Go To Market Strategy; B2B2C; B2B Vs. B2C; Health & Wellness; AI; Machine Learning; Female Ceo; Female Protagonist; Science-based; Science And Technology Studies; Ecommerce; Applications; DTC; Direct To Consumer Marketing; US Health Care; "USA,"; Innovation; Pricing; Business Growth; Segmentation; Distribution Channels; Growth and Development Strategy; Business Startups; Science-Based Business; Health; Innovation and Invention; Marketing; Information Technology; Business Growth and Maturation; E-commerce; Applications and Software; Health Industry; Technology Industry; Insurance Industry; Information Technology Industry; Food and Beverage Industry; Israel; United States
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Israeli, Ayelet, and David Lane. "DayTwo: Going to Market with Gut Microbiome." Harvard Business School Case 519-010, March 2019.
  • June 2020
  • Teaching Note

Shiseido Acquires Drunk Elephant

By: Jill Avery
On October 7, 2019, the Shiseido Group announced that it would acquire clean skincare brand Drunk Elephant for $845 million, a valuation of 8.5 times sales. Did Shiseido pay too much or too little for this brand asset? How much was the Drunk Elephant brand worth and... View Details
Keywords: Brand Management; Brand Valuation; Brand Equity; Brand Value; Mergers & Acquisitions; Startup; DTC; Brand Portfolio Strategy; Marketing; Marketing Strategy; Brands and Branding; Mergers and Acquisitions; Valuation; Entrepreneurship; Business Startups; Beauty and Cosmetics Industry; Consumer Products Industry; United States; Japan; Asia; North America
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Avery, Jill. "Shiseido Acquires Drunk Elephant." Harvard Business School Teaching Note 520-121, June 2020.
  • March 2014 (Revised September 2017)
  • Case

salaUno: Eliminating Needless Blindness in Mexico

By: Richard Hamermesh, Regina Garcia Cueller and Valeria Moy
In May 2013 the co-founders and co-CEOs of salaUno, Javier Okhuysen and Carlos Orellana, were encouraged by the results of their fledgling start-up. salaUno was founded as a for-profit enterprise in order to have the capital needed for rapid growth and to fulfill its... View Details
Keywords: Medical Services; Developing Countries; Developing Markets; Health Care Industry; Health Services; Healthcare Ventures; Healthcare Startups; Health Care and Treatment; Health; Business Startups; Developing Countries and Economies; Growth and Development Strategy; Health Industry; Mexico; Mexico City
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Hamermesh, Richard, Regina Garcia Cueller, and Valeria Moy. "salaUno: Eliminating Needless Blindness in Mexico." Harvard Business School Case 814-041, March 2014. (Revised September 2017.)
  • March 2015 (Revised January 2024)
  • Case

CV Ingenuity (A): How to Evaluate the Commercial Viability of New Health Care Technologies

By: Regina E. Herzlinger and Andrew Otazo
Duke Rohlen (HBS MBA ’01) hoped to win over a prominent venture capital investor for Series B financing of his firm CVI that was creating a drug-eluting balloon (DES) to treat peripheral arterial disease. As a second-mover, Duke felt he was more likely to acquire... View Details
Keywords: CV Ingenuity; CVI; Drug Eluting Balloon; DEB; Drug Eluting Stent; Angioplasty Balloon; FoxHollow; Medical Device; Medical Device Startup; Premarket Approval; PMA; Lutonix; Stellarex; LEVANT; ILLUMENATE; Clinical Trials; Peripheral Arterial Disease; PAD; Healthcare Startups; Covidien; Health Care and Treatment; Health Testing and Trials; Business Startups; Commercialization; Health Industry; Medical Devices and Supplies Industry; United States; Europe
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Herzlinger, Regina E., and Andrew Otazo. "CV Ingenuity (A): How to Evaluate the Commercial Viability of New Health Care Technologies." Harvard Business School Case 315-045, March 2015. (Revised January 2024.)
  • March 2015 (Revised February 2022)
  • Supplement

CV Ingenuity (B): Epilogue

By: Regina E. Herzlinger and Andrew Otazo
Duke Rohlen used a lea-nfunding, iconoclastic strategy for his start up for a drug eluding balloon for peripheral artery disease. His giant competitors were first movers. Did Duke obtain the funding he sought? How did his DEB fare versus that of his competitors? The... View Details
Keywords: CV Ingenuity; CVI; Drug Eluting Balloon; DEB; Drug Eluting Stent; Angioplasty Balloon; FoxHollow; Medical Device; Medical Device Startup; Premarket Approval; PMA; Lutonix; Stellarex; LEVANT; ILLUMENATE; Clinical Trials; Peripheral Arterial Disease; PAD; Healthcare Startups; Covidien; Health Care and Treatment; Health Testing and Trials; Business Startups; Commercialization; Strategy; Health Industry; Medical Devices and Supplies Industry; United States; Europe
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Herzlinger, Regina E., and Andrew Otazo. "CV Ingenuity (B): Epilogue." Harvard Business School Supplement 315-087, March 2015. (Revised February 2022.)
  • 13 Jul 2016
  • HBS Case

How Uber, Airbnb, and Etsy Attracted Their First 1,000 Customers

New businesses often struggle finding their first customers. The challenge is even more difficult with startups in the sharing economy that launch as platforms connecting independent service providers with consumers. Take Uber. Its... View Details
Keywords: by Michael Blanding; Retail; Service; Transportation
  • January 2014
  • Teaching Plan

MedImmune Ventures

By: Richard Hamermesh and Andrew Otazo
"MedImmune Ventures" highlights the problems faced by corporate venture capital firms, the challenges of investing in early-stage healthcare, and the difficulty of operating in distant markets. View Details
Keywords: MedImmune Ventures; NeuProtect; Corporate Venture Capital; Ron Laufer; Australia; Starfish Ventures; AstraZeneca; MEVE; Healthcare; Startup; Venture Capital; Business Startups; Health Industry; Australia; United States
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Hamermesh, Richard, and Andrew Otazo. "MedImmune Ventures." Harvard Business School Teaching Plan 814-039, January 2014.
  • January 2020
  • Case

Celata Bioinnovations

By: John R. Wells and Benjamin Weinstock
In December 2019, Jon Hu (HBS ‘19) and Dr. Samantha Dale Strasser, co-founders of Celata Bioinnovations, were raising $1 million to launch their company. They had founded Celata less than six months earlier with the aim of redefining the drug discovery process.... View Details
Keywords: Drug Development; Drug Discovery; Drug Trials; Pharmaceutical Companies; Pharmaceutical Company; Pharmaceuticals; Therapeutics; Biologics; Biotech; Biotechnology; Biopharmacy Company; Biochemistry; Technology Commercialization; Technology Companies; Drug Testing; Startup; Start-up; Startups; Start-ups; Startup Financing; Strategic Decision Making; Strategic Decisions; Strategic Evolution; FDA; Food And Drug Administration; Clinical Trials; Disease Management; Market Attractiveness; Market Entry; Market Opportunities; Health Disorders; Technological Innovation; Information Technology; Commercialization; Business Startups; Finance; Decision Making; Strategy; Market Entry and Exit; Opportunities; Pharmaceutical Industry; Biotechnology Industry
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Wells, John R., and Benjamin Weinstock. "Celata Bioinnovations." Harvard Business School Case 720-427, January 2020.
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