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  • 2025
  • Working Paper

Antibiotic Treatments for Ulcers--Eradicating H-Pylori Infections: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes how a chance discovery of bacteria that infect stomach linings completely changed how physicians treat ulcers. Specifically, we chronicle how: 1) two Australian physicians brought the bacterial infection to the world’s attention and... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Antibiotic Treatments for Ulcers--Eradicating H-Pylori Infections: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-006, July 2019. (Revised January 2025.)
  • 22 Nov 2016
  • First Look

November 22, 2016

Care Thaddeus Fulford-Jones and Eric Weiss, founders of healthcare technology startup Radial Analytics, have been busy developing a software program designed to save hospitals money and improve patient View Details
Keywords: Sean Silverthorne
  • September 1995
  • Case

Ares-Serono

By: Michael Y. Yoshino, Jean-Pierre Jeannet and Carin-Isabel Knoop
Ares Serono, a medium-size Swiss pharmaceutical company, is the global leader in the field of fertility drugs. The company has successfully transformed into one of the very few biotech firms in Europe. The case treats a set of major strategic and organizational... View Details
Keywords: Geographic Location; Globalized Firms and Management; Asset Management; Balance and Stability; Expansion; Digital Platforms; Leadership Development; Health Care and Treatment; Transformation; Family Business; Problems and Challenges; Pharmaceutical Industry; Biotechnology Industry; Switzerland; Europe
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Yoshino, Michael Y., Jean-Pierre Jeannet, and Carin-Isabel Knoop. "Ares-Serono." Harvard Business School Case 396-035, September 1995.
  • 10 Jun 2002
  • Research & Ideas

Disruption: The Art of Framing

potential shared resources. Johnson & Johnson has done this effectively with many of its health care companies—acquiring separate platforms of growth and leaving them largely independent. Knight Ridder... View Details
Keywords: by Clark Gilbert & Joseph L. Bower
  • 20 Jan 2017
  • Research & Ideas

Here’s How Businessman Trump Is Likely to Approach the Presidency

different needs from small business. Small businesses have a more difficult time accessing capital, providing health care to their employees, navigating complex regulations at every level of government, and... View Details
Keywords: by Christina Pazzanese
  • 18 Dec 2018
  • First Look

New Research and Ideas, December 18, 2018

R&D-intensive firms react to negative shocks to their existing products? We explore this question using detailed project-level data from drug development firms. Using FDA Public Health Advisories as an exogenous and idiosyncratic... View Details
Keywords: Dina Gerdeman
  • 13 Apr 2020
  • Research & Ideas

Small Businesses Are Worse Off Than We Thought

in-person operations, sinking demand to near zero. Professional services businesses have fared better, but they have not been spared—just 63 percent say they could weather a four-month public health lockdown. [div class=infogram-embed... View Details
Keywords: by Kristen Senz; Financial Services
  • 14 May 2013
  • First Look

First Look: May 14

P/E industries, which have a negative valuation change in the year after the investment. 2006 New England Journal of Medicine Leading Clinicians and Clinicians Leading By: Bohmer, Richard M.J. Abstract—More effective models of care... View Details
Keywords: Sean Silverthorne
  • 03 Apr 2018
  • First Look

New Research and Ideas, April 3, 2018

of spending on traditional aid programs in areas such as health care and food access in developing countries, GiveDirectly transfers cash directly to the poor. As experiments have shown this approach to be... View Details
Keywords: Sean Silverthorne
  • 14 Nov 2019
  • Book

Lifting the Lid on Turkey's Hidden Business History

in health and education, including founding Koç University in 1992, now one of the most prestigious universities in the country. Silverthorne: In what ways is Turkish business history distinctive and in what ways does it share... View Details
Keywords: by Sean Silverthorne
  • 05 Nov 2007
  • What Do You Think?

Why Is Succession So Badly Managed?

top-level management from outside is a natural outcome of the belief that almost any of our competitors has better people than we do." And Lowell Kuehn posited that "the outsider is all promise, while the insider is a known... View Details
Keywords: Re: James L. Heskett
  • 17 Nov 2003
  • Research & Ideas

Lessons from a Nasty Trade Dispute

of both direct and indirect subsidies in industries throughout the world, and careful attention must be paid to the advantages that might accrue to competitors in very subtle ways. Q: To what extent do you think managers can benefit from... View Details
Keywords: by Cynthia Churchwell
  • 12 Feb 2008
  • First Look

First Look: February 12, 2007

firms. They also affect trading signal classifications, back-testing inferences, track records of individual analysts, and models of analysts' career outcomes in the three years following the changes. Long-Run Stockholder Consumption Risk... View Details
Keywords: Martha Lagace
  • March 2017
  • Case

Cantel Medical

By: John R. Wells and Gabriel Ellsworth
Cantel Medical Corporation provided infection prevention and control products and services for patients, caregivers, and other healthcare providers. In 2016, Cantel generated sales of $665 million and net profits of $60 million, double the levels of five years earlier.... View Details
Keywords: Cantel; Charles Diker; Furniture Industry; Matrix Organization; Acquisition; Mergers and Acquisitions; Business Conglomerates; Business Units; Business Growth and Maturation; Business Organization; For-Profit Firms; Chemicals; Profit; Revenue; Geographic Scope; Multinational Firms and Management; Health; Health Care and Treatment; Business History; Business or Company Management; Goals and Objectives; Growth and Development Strategy; Organizational Structure; Problems and Challenges; Research and Development; Opportunities; Strategy; Adaptation; Business Strategy; Competitive Strategy; Corporate Strategy; Diversification; Expansion; Information Technology; Health Industry; Health Industry; Health Industry; Health Industry; Health Industry; Health Industry; United States; New Jersey
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Wells, John R., and Gabriel Ellsworth. "Cantel Medical." Harvard Business School Case 717-482, March 2017.
  • 13 Aug 2020
  • Research & Ideas

6 Ways to Support COVID-Weary Employees

Petriglieri, associate professor at INSEAD: Making special accommodations for employees who are at high-risk of COVID infection is legally, morally, and reputationally the right course of action for employers. In many countries, employers have a legal duty of View Details
Keywords: by Dina Gerdeman
  • 20 Jan 2015
  • First Look

First Look: January 20

rededicating themselves to improving the value they deliver to their patients: better outcomes and lower costs. Time-driven activity-based costing offers the potential for clinicians to redesign their care... View Details
Keywords: Sean Silverthorne
  • 05 Jul 2006
  • First Look

First Look: July 5, 2006

MaterialsAncora: A Private University in the Health Care of the Poor 306-088 Project Ancora signals the entry of the private sector into primary healthcare for Chile's poor. On a commercial basis, it seeks... View Details
Keywords: Sean Silverthorne
  • 15 Sep 2011
  • Research & Ideas

High Ambition Leadership

returns on the investments in our assets. And then we will be able to grow and deliver more health care to more people." But what was most distinctive was the extent to which Gooding galvanized the... View Details
Keywords: by Martha Lagace
  • 22 Oct 2012
  • Research & Ideas

Not Your Father’s State-Run Capitalism

enterprises, where directors' private interests diverged from the interest of the firms they managed. "In the past, managers of SOEs were sometimes selected according to political interests, and there was no transparency," says Musacchio. "You see a more View Details
Keywords: by Michael Blanding
  • 14 Feb 2017
  • First Look

First Look at New Research: February 14

institutionalized in America over subsequent decades in a way that has been difficult to replicate in other countries. The role of history helps to explain why. Publisher's link: https://www.hbs.edu/faculty/Pages/item.aspx?num=52209 December 8, 2016 Harvard Business... View Details
Keywords: Sean Silverthorne
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