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  • All HBS Web  (2,463)
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  • All HBS Web  (2,463)
    • People  (6)
    • News  (577)
    • Research  (1,761)
    • Events  (11)
    • Multimedia  (14)
  • Faculty Publications  (1,392)
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  • 01 Jun 2000
  • News

The Business of Biotech

New Year's Eve 1999 gave revelers a once-in-a-lifetime opportunity for celebration - the exhilarating thrill of ringing in a year that's always had an aura of science fiction mystery. When the champagne... View Details
Keywords: Julia Hanna
  • November 2012 (Revised January 2013)
  • Case

Companion Diagnostics: Uncertainties for Approval and Reimbursement

By: Richard G. Hamermesh, Norman C. Selby and Phillip Andrews
The FDA approvals of novel therapeutics were seen as signs in the personalized medicine community of real progress in the growth of personalized medicine. The FDA's approval of such drugs, along with companion diagnostics, suggested a shift in thinking and regulatory... View Details
Keywords: Models Of Reimbursement; Personalized Medicine; Regulation; Healthcare Reform; Health Care and Treatment; Health Industry; United States
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Hamermesh, Richard G., Norman C. Selby, and Phillip Andrews. "Companion Diagnostics: Uncertainties for Approval and Reimbursement." Harvard Business School Case 813-037, November 2012. (Revised January 2013.)
  • 2006
  • Book

The Soul of a Doctor

By: Susan Pories, Sachin H. Jain and Gordon Harper
Collection of essays written by Harvard Medical School students focused on the experiencing of transitioning from clinician to student. Particular emphasis is given to the role of student as an "embedded critic," i.e. a practitioner knowledgeable about medicine, but... View Details
Keywords: Transition; Practice; Personal Development and Career; Education; Health Care and Treatment; Emotions
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Pories, Susan, Sachin H. Jain and Gordon Harper, eds. The Soul of a Doctor. Chapel Hill: Algonquin Books, 2006.
  • 02 Jan 2007
  • Research & Ideas

Most Popular Articles of 2006

Enter the concept of the "channel steward." The Real Wal-Mart Effect Critics are lining up to take shots at Wal-Mart's treatment of workers and a host View Details
Keywords: by Sean Silverthorne
  • 30 Apr 2001
  • Research & Ideas

Entering the Age of Alliances

team, also owned by Perini at that time. The team became a major sponsor of the Jimmy Fund, helping raise money for the treatment of children with cancer. Although the Jimmy... View Details
Keywords: by James Austin
  • November 2002
  • Compilation

Four Principles of Biomedical Ethics: Definitions and Examples

By: Sandra J. Sucher
Introduces four principles of biomedical ethics, excerpted from Principles of Biomedical Ethics, Tom L. Beauchamp and James F. Childress (Oxford University Press, 2001). The principles provide a conceptual framework for the analysis and resolution of moral problems... View Details
Keywords: Framework; Moral Sensibility; Health Care and Treatment; Distribution; Problems and Challenges; Research; Emotions; Management Analysis, Tools, and Techniques; Pharmaceutical Industry; Health Industry
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Sucher, Sandra J. "Four Principles of Biomedical Ethics: Definitions and Examples." Harvard Business School Compilation 603-079, November 2002.
  • Article

Consumers' Misunderstanding of Health Insurance

By: George Loewenstein, Joelle Y. Friedman, Barbara McGill, Sarah Ahmad, Suzanne Linck, Stacey Sinkula, John Beshears, James J. Choi, Jonathan Kolstad, David Laibson, Brigitte C. Madrian, John A. List and Kevin G. Volpp
We report results from two surveys of representative samples of Americans with private health insurance. The first examines how well Americans understand, and believe they understand, traditional health insurance coverage. The second examines whether those insured... View Details
Keywords: Behavioral Economics; Simplification; Insurance; Consumer Behavior; Health Care and Treatment; Cognition and Thinking; Insurance Industry; Health Industry; United States
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Loewenstein, George, Joelle Y. Friedman, Barbara McGill, Sarah Ahmad, Suzanne Linck, Stacey Sinkula, John Beshears, James J. Choi, Jonathan Kolstad, David Laibson, Brigitte C. Madrian, John A. List, and Kevin G. Volpp. "Consumers' Misunderstanding of Health Insurance." Journal of Health Economics 32, no. 5 (September 2013): 850–862.
  • 14 Jan 2019
  • Op-Ed

These 4 CEOs Created a New Standard of Leadership

Clinic’s historic mission of putting patients first. He prioritized Mayo’s focus on the most complex diseases patients faced, using its research to develop new treatments for many diseases. He reorganized... View Details
Keywords: by Bill George; Health; Banking; Food & Beverage; Consumer Products
  • 2022
  • Article

Improving Efficiency and Reducing Costs of MRI-Guided Prostate Brachytherapy Using Time-Driven Activity-Based Costing

By: Nikhil G. Thaker, Rajat J. Kudchadker, James R. Incalcaterra, Tharakeswara K. Bathala, Robert S. Kaplan, Ankit Agarwal, Deborah A. Kuban, Benjamin D. Frank, Prajnan Das, Thomas W. Feeley and Steven J. Frank
Integrated quality improvement (QI) and cost reduction strategies can help increase value in cancer care. We applied standard QI and TDABC methods to improve workflow efficiency and reduce costs for MRI-guided prostate brachytherapy. We constructed process maps,... View Details
Keywords: Brachytherapy; Quality Improvement; Prostate; Time-Driven Activity-Based Costing; Cost Accounting; Health Care and Treatment; Performance Efficiency; Health Industry
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Thaker, Nikhil G., Rajat J. Kudchadker, James R. Incalcaterra, Tharakeswara K. Bathala, Robert S. Kaplan, Ankit Agarwal, Deborah A. Kuban, Benjamin D. Frank, Prajnan Das, Thomas W. Feeley, and Steven J. Frank. "Improving Efficiency and Reducing Costs of MRI-Guided Prostate Brachytherapy Using Time-Driven Activity-Based Costing." Brachytherapy 21, no. 1 (2022): 49–54.
  • 11 Dec 2014
  • News

Improving the business of medicine

As founder and managing partner of KBL Ventures, Dr. Marlene Krauss (MBA 1967, MD 1979) combines her business and medical training to bring health care device and bio-tech ventures to market. (Published December 2014) View Details
  • September 2017 (Revised July 2023)
  • Case

Adaptive Platform Trials: The Clinical Trial of the Future?

By: Ariel D. Stern and Sarah Mehta
In July 2017, Dr. Brian M. Alexander, president and CEO of the AGILE Research Foundation, was preparing to launch a new type of clinical trial—an adaptive platform trial—to study potential therapies for glioblastoma (GBM), an aggressive form of brain cancer.... View Details
Keywords: Clinical Trials; Cancer; Adaptive Platform Trials; Platform Trials; Adaptive Trials; Glioblastoma; Health; Health Care and Treatment; Health Testing and Trials; Business Strategy; Innovation Strategy; Health Industry; United States
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Stern, Ariel D., and Sarah Mehta. "Adaptive Platform Trials: The Clinical Trial of the Future?" Harvard Business School Case 618-025, September 2017. (Revised July 2023.)
  • August 2023
  • Article

Impact of Social Needs Case Management on Use of Medical and Behavioral Health Services: Secondary Analysis of a Randomized Controlled Trial

By: Mark D. Fleming, Crystal Guo, Margae Knox, Daniel M. Brown, Elizabeth A. Hernandez and Amanda L. Brewster
Social needs case management is an increasingly common strategy used by health care organizations to address integrated health and social needs. These programs connect patients to resources such as food assistance, housing, transportation, or income benefits, in... View Details
Keywords: Health Care and Treatment; Medical Specialties; Programs; Human Needs; Welfare; Health Industry; California
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Fleming, Mark D., Crystal Guo, Margae Knox, Daniel M. Brown, Elizabeth A. Hernandez, and Amanda L. Brewster. "Impact of Social Needs Case Management on Use of Medical and Behavioral Health Services: Secondary Analysis of a Randomized Controlled Trial." Annals of Internal Medicine 176, no. 8 (August 2023): 1139–1141.
  • 27 May 2015
  • Research & Ideas

Build 'Scaffolds' to Improve Performance of Temporary Teams

"Four minutes," a triumphant Amy C. Edmondson exclaims as she arrives at her Harvard Business School office, clutching a bike helmet and explaining that her commute is 10 minutes faster by bicycle than by car. Edmondson, the Novartis Professor View Details
Keywords: by Roberta Holland; Health
  • June 2024
  • Article

Valuing the Societal Impact of Medicines and Other Health Technologies: A User Guide to Current Best Practices

By: Jason Shafrin, Jaehong Kim, Joshua T. Cohen, Louis P. Garrison, Dana A. Goldman, Jalpa A. Doshi, Joshua Krieger, Darius N. Lakdawalla, Peter J. Neumann, Charles E. Phelps, Melanie D. Whittington and Richard Willke
This study argues that value assessment conducted from a societal perspective should rely on the Generalized Cost-Effectiveness Analysis (GCEA) framework proposed herein. Recently developed value assessment inventories—such as the Second Panel on Cost-Effectiveness’s... View Details
Keywords: Health Care and Treatment; Valuation; Cost vs Benefits; Society
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Shafrin, Jason, Jaehong Kim, Joshua T. Cohen, Louis P. Garrison, Dana A. Goldman, Jalpa A. Doshi, Joshua Krieger, Darius N. Lakdawalla, Peter J. Neumann, Charles E. Phelps, Melanie D. Whittington, and Richard Willke. "Valuing the Societal Impact of Medicines and Other Health Technologies: A User Guide to Current Best Practices." Forum of Health Economics and Policy 27, no. 1 (June 2024): 29–116.
  • 01 Dec 2004
  • News

The Future of Stem Cells

and cord-blood stem cells for the treatment of some cancers, genetic disorders, and certain immune deficiencies. (Cord blood contains stem cells; individuals can bank their own until they, or close blood... View Details
Keywords: Garry Emmons
  • 2001
  • Chapter

Publicly Funded Science and the Productivity of the Pharmaceutical Industry

By: Rebecca Henderson and Ian Cockburn
U.S. taxpayers funded $14.8 billion of health related research last year, four times the amount that was spent in 1970 in real terms. In this paper we evaluate the impact of these huge expenditures on the technological performance of the pharmaceutical industry. While... View Details
Keywords: Public Sector; Science-Based Business; Research and Development; Sovereign Finance; Pharmaceutical Industry
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Henderson, Rebecca, and Ian Cockburn. "Publicly Funded Science and the Productivity of the Pharmaceutical Industry." In Innovation Policy and the Economy, Volume 1, edited by Adam B. Jaffe, Josh Lerner, and Scott Stern, 1–34. MIT Press, 2001.
  • July 2023
  • Article

Before or After? The Effects of Payment Decision Timing in Pay-What-You-Want Contexts

By: Raghabendra P. KC, Vincent Mak and Elie Ofek
We study how payment decision timing—before versus after product delivery—influences consumer payment under pay-what-you-want pricing. We focus on situations where there is minimal change in consumer uncertainty regarding the product before versus after receiving it.... View Details
Keywords: Price; Behavior; Valuation; Philanthropy and Charitable Giving
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KC, Raghabendra P., Vincent Mak, and Elie Ofek. "Before or After? The Effects of Payment Decision Timing in Pay-What-You-Want Contexts." Journal of Marketing 87, no. 4 (July 2023): 618–635.
  • July 2019
  • Article

The Impact of Price Regulation on the Availability of New Drugs in Germany

By: Ariel Dora Stern, Felicitas Pietrulla, Annika Herr, Aaron S. Kesselheim and Ameet Sarpatwari
The 2011 German Pharmaceutical Market Restructuring Act (“AMNOG”) subjected branded, non-rare disease drugs to price regulation based on an assessment of their clinical benefit. Assessment outcomes range from “major added benefit” to “less benefit than the appropriate... View Details
Keywords: Regulation; Pharmaceuticals; Healthcare; Health Care and Treatment; Price; Governing Rules, Regulations, and Reforms; Pharmaceutical Industry; Germany
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Stern, Ariel Dora, Felicitas Pietrulla, Annika Herr, Aaron S. Kesselheim, and Ameet Sarpatwari. "The Impact of Price Regulation on the Availability of New Drugs in Germany." Health Affairs 38, no. 7 (July 2019): 1182–1187.
  • Article

Managing the Use and Dissemination of Information about Biomarkers: The Importance of Incentive Structures.

By: Ariel Dora Stern
The use of biomarkers holds great promise for the development of new therapeutics and the acceleration of clinical research. However, biomarkers must be validated—a complex and costly endeavor. Importantly, biomarker validation is meaningfully shaped by economic and... View Details
Keywords: Biomarkers; Information Management; Health Care and Treatment; Motivation and Incentives
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Stern, Ariel Dora. "Managing the Use and Dissemination of Information about Biomarkers: The Importance of Incentive Structures." Journal of Law, Medicine & Ethics 47, no. 3 (September 2019): 396–397.
  • 29 Sep 2014
  • News

The Rise of the MD/MBA

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