Publications

January–February 2022
Article

Mobilizing the U.S. Military’s TRICARE Program for Value-Based Care: A Report From the Defense Health Board

By: Robert S. Kaplan, Paul R. Schaettle, Vivian S. Lee, Michael D. Parkinson, Gregory H. Gorman and Michael-Anne Browne

The U.S. Military Health System spends about $50 billion annually through its TRICARE health plans to provide care to 9.6 million active duty service members, retirees, and their families. TRICARE, historically, has used the predominant U.S. fee-for-service payment... View Details

Keywords: Military Health System; Value-based Healthcare; Health Care and Treatment; United States

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April 2006
Case

Adrian Ivinson at the Harvard Center for Neurodegeneration and Repair

By: Robert Steven Kaplan and Ayesha Kanji

Adrian Ivinson is the director of Harvard Center for Neurodegeneration and Repair (HCNR), a not-for-profit research center at the Harvard Medical School (HMS). The center was started in late 2000 with a gift of $37.5 million from an anonymous donor. Its mandate was to... View Details

Keywords: Leadership Style; Power and Influence; Organizational Culture; Research and Development; Nonprofit Organizations; Motivation and Incentives; Change Management; Alignment; Collaborative Innovation and Invention; Health Industry; Massachusetts

2023
Article

Benchmarking Large Language Models on CMExam—A Comprehensive Chinese Medical Exam Dataset

By: Junling Liu, Peilin Zhou, Yining Hua, Dading Chong, Zhongyu Tian, Andrew Liu, Helin Wang, Chenyu You, Zhenhua Guo, Lei Zhu and Michael Lingzhi Li

Recent advancements in large language models (LLMs) have transformed the field of question answering (QA). However, evaluating LLMs in the medical field is challenging due to the lack of standardized and comprehensive datasets. To address this gap, we introduce CMExam,... View Details

Keywords: Large Language Model; AI and Machine Learning; Analytics and Data Science; Health Industry

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August 2016 (Revised August 2016)
Teaching Note

Intrapreneurship at DaVita Healthcare Partners

By: Joseph B. Fuller and Matthew Preble

DaVita Healthcare Partners Inc. (DaVita) is one of the U.S.'s leading dialysis providers, a process whereby persons with end-stage renal disease (ESRD) are connected to a machine that performs the functions of a healthy kidney. Kent Thiry, DaVita's CEO, has expanded... View Details

Keywords: Intrapreneurship; Entrepreneurial Organizations; Startup Management; Startup; Strategic Positioning; Corporate Entrepreneurship; Corporate Strategy; Business Startups; Strategic Planning; Competitive Strategy; Health Industry; United States

April 2024 (Revised December 2024)
Case

Anthropic: Building Safe AI

By: Shikhar Ghosh and Shweta Bagai

In late 2024, Anthropic, a leading AI safety and research company, achieved a significant breakthrough with computer use capabilities that allowed AI to interact with computers like humans. Co-founded by former OpenAI employees and known for its generative AI... View Details

Keywords: AI and Machine Learning; Corporate Accountability; Corporate Social Responsibility and Impact; Business Growth and Maturation; Corporate Strategy; Technology Industry; United States

10 Oct 2007
First Look

First Look: First Look: October 10

Working PapersTesting Limits to Policy Reversal: Evidence from Indian Privatizations Authors:Siddhartha G. Dastidar, Raymond Fisman, and Tarun Khanna Abstract We examine the effect of regime change on privatization using the 2004 election surprise in India. The... View Details

Keywords: Martha Lagace

2018
Chapter

The Orphan Drug Act at 35: Observations and an Outlook for the Twenty-First Century

By: Nicholas Bagley, Benjamin Berger, Amitabh Chandra, Craig Garthwaite and Ariel Dora Stern

On the 35th anniversary of the adoption of the Orphan Drug Act (ODA), we describe the enormous changes in the markets for therapies for rare diseases that have emerged over recent decades. The most prominent example is the fact that the profit-maximizing price of new... View Details

Keywords: Health Care and Treatment; Laws and Statutes; Research and Development; Investment; Markets; Monopoly

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January 2017
Supplement

Intrapreneurship at DaVita HealthCare Partners: Cash Flow Tool

By: Joseph B. Fuller and Christopher Payton

DaVita Healthcare Partners Inc. (DaVita) is one of the U.S.'s leading dialysis providers, a process whereby persons with end-stage renal disease (ESRD) are connected to a machine that performs the functions of a healthy kidney. Kent Thiry, DaVita's CEO, has expanded... View Details

Keywords: Intrapreneurship; Entrepreneurial Organizations; Startup Management; Startup; Strategic Positioning; Corporate Entrepreneurship; Corporate Strategy; Business Startups; Strategic Planning; Competitive Strategy; Health Industry; United States

09 Nov 2016
HBS Seminar

Robert A. Miller, Tepper School of Business, Carnegie Mellon University

Web

Health & Safety Protocols

What to Expect When Coming to Campus Last updated: 13 APR 2023 The health, safety, and well-being of our entire HBS community remain our top priority. We continue to monitor health and safety protocols as provided by the U.S. Centers for View Details

26 May 2015
First Look

First Look: May 26

widespread dissemination of its sole product, Twine. Twine was a cloud-based platform that enabled patients to create and manage chronic disease treatment plans in conjunction with their primary care providers and specialized coaches.... View Details

Keywords: Sean Silverthorne

2015
Article

Scalable Detection of Anomalous Patterns With Connectivity Constraints

By: Skyler Speakman, Edward McFowland III and Daniel B. Neill

We present GraphScan, a novel method for detecting arbitrarily shaped connected clusters in graph or network data. Given a graph structure, data observed at each node, and a score function defining the anomalousness of a set of nodes, GraphScan can efficiently and... View Details

Keywords: Biosurveillance; Event Detection; Graph Mining; Scan Statistics; Spatial Scan Statistic

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June 2008 (Revised July 2008)
Case

The Miami Project to Cure Paralysis

By: Robert Steven Kaplan, Christopher Marquis and Brent Kazan

Marc Buoniconti is the co-founder of the Miami Project to Cure Paralysis, a nonprofit medical research organization. The project was founded in 1985 by Marc and his father Nick, a former Hall of Fame football player, when Marc suffered a spinal cord injury. In 2007,... View Details

Keywords: Investment; Philanthropy and Charitable Giving; Health Testing and Trials; Leadership; Growth and Development Strategy; Mission and Purpose; Research and Development; Nonprofit Organizations; Health Industry; Miami

07 Feb 2012
First Look

First Look: February 7

efforts all around GE. But will this focus enable GE to achieve and maintain market leadership across a healthcare market that is being buffeted by strong currents, including cost pressures, changes in chronic disease patterns, and... View Details

Keywords: Sean Silverthorne

May 2023 (Revised June 2023)
Supplement

Novartis (C): Reimagining Medicine

By: Ramon Casadesus-Masanell, Claudio Feser, Karolin Frankenberger and David Redaschi

This case unfolds around the first-ever approved personalized cancer treatment, how Novartis wrapped it into a new business model design, and how Novartis scaled it. Novartis — one of the largest pharmaceutical companies in the world — is, among other ventures,... View Details

Keywords: Health Testing and Trials; Health Care and Treatment; Business Model; Problems and Challenges; Pharmaceutical Industry; Switzerland

March 2023 (Revised June 2025)
Case

Close Concerns: Diabetes Research and Advocacy

By: Regina E. Herzlinger and Brian L. Walker

This case describes the Exit considerations of Kelly Close, HBS MBA, and founder of the primary distributor of diabetes newsletters. It is part of the fourth module in the Innovating in Health Care HBS MBA course, which contains cases of other health care firms that... View Details

Keywords: Diabetes; Health; Health Care; Health Care And Treatment; Health Care Outcomes; Health Care Industry; Knowledge Dissemination; Outcome or Result; Equality and Inequality; Business Model; Entrepreneurship

2011
Article

Scalable Detection of Anomalous Patterns With Connectivity Constraints

By: Skyler Speakman, Edward McFowland III and Daniel B. Neill

We present GraphScan, a novel method for detecting arbitrarily shaped connected clusters in graph or network data. Given a graph structure, data observed at each node, and a score function defining the anomalousness of a set of nodes, GraphScan can efficiently and... View Details

Keywords: Biosurveillance; Event Detection; Graph Mining; Scan Statistics; Spatial Scan Statistic