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  • September 2017 (Revised July 2023)
  • Case

Adaptive Platform Trials: The Clinical Trial of the Future?

By: Ariel D. Stern and Sarah Mehta
In July 2017, Dr. Brian M. Alexander, president and CEO of the AGILE Research Foundation, was preparing to launch a new type of clinical trial—an adaptive platform trial—to study potential therapies for glioblastoma (GBM), an aggressive form of brain cancer.... View Details
Keywords: Clinical Trials; Cancer; Adaptive Platform Trials; Platform Trials; Adaptive Trials; Glioblastoma; Health; Health Care and Treatment; Health Testing and Trials; Business Strategy; Innovation Strategy; Health Industry; United States
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Stern, Ariel D., and Sarah Mehta. "Adaptive Platform Trials: The Clinical Trial of the Future?" Harvard Business School Case 618-025, September 2017. (Revised July 2023.)

    Rosabeth M. Kanter

    Rosabeth Moss Kanter holds the Ernest L. Arbuckle Professorship at Harvard Business School, specializing in strategy, innovation, and leadership for change. Her strategic and practical insights guide leaders worldwide through teaching, writing, and direct... View Details

    Keywords: health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care; health care
    • April 1983 (Revised June 2003)
    • Case

    Shouldice Hospital Limited

    By: James L. Heskett
    Various proposals are set forth for expanding the capacity of the hospital. In assessing them, serious consideration has to be given to the culture of the organization and the importance of preserving it in a service delivery system. In addition to issues of capacity... View Details
    Keywords: Expansion; Health Care and Treatment; Performance Capacity; Organizational Culture; Service Delivery; Growth Management; Strategic Planning; Quality; Social Enterprise; Health Industry; Canada
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    Heskett, James L. "Shouldice Hospital Limited." Harvard Business School Case 683-068, April 1983. (Revised June 2003.)
    • Web

    Aligning Reimbursement with Value - Institute For Strategy And Competitiveness

    HBS ISC Health Care Health Care Value-Based Health Care View Details
    • May 2024 (Revised February 2025)
    • Case

    Choosing the Course of Passion: Brooke Boyarsky Pratt at knownwell

    By: Jon M. Jachimowicz and Alexis Lefort
    Brooke Boyarsky Pratt (HBS ’13) enjoyed considerable success in her early career, quickly climbing the ranks to associate partner at McKinsey, and later becoming an executive vice president at Berkadia, a Berkshire Hathaway portfolio company. Throughout these years,... View Details
    Keywords: Passion; Career; Career Planning; Purpose; Personal Development and Career; Mission and Purpose; Identity; Business Startups; Health Care and Treatment; Health Disorders; Growth and Development Strategy; Market Entry and Exit; Health Industry; United States
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    Jachimowicz, Jon M., and Alexis Lefort. "Choosing the Course of Passion: Brooke Boyarsky Pratt at knownwell." Harvard Business School Case 424-040, May 2024. (Revised February 2025.)
    • Web

    HBS - The year in Review

    how to eradicate inequality, as well as the Blavatnik Fellowship in Life Science Entrepreneurship , which is a one-year program for alumni in health care startups. Recipients for 2021-22 were Dan Ahlstedt... View Details
    • Article

    A Megastudy of Text-Based Nudges Encouraging Patients to Get Vaccinated at an Upcoming Doctor's Appointment

    By: Katherine L. Milkman, Mitesh S. Patel, Linnea Gandhi, Heather N. Graci, Dena M. Gromet, Hung Ho, Joseph S. Kay, Timothy W. Lee, Modupe Akinola, John Beshears, Jonathan E. Bogard, Alison Buttenheim, Christopher F. Chabris, Gretchen B. Chapman, James J. Choi, Hengchen Dai, Craig R. Fox, Amir Goren, Matthew D. Hilchey, Jillian Hmurovic, Leslie K. John, Dean Karlan, Melanie Kim, David Laibson, Cait Lamberton, Brigitte C. Madrian, Michelle N. Meyer, Maria Modanu, Jimin Nam, Todd Rogers, Renante Rondina, Silvia Saccardo, Maheen Shermohammed, Dilip Soman, Jehan Sparks, Caleb Warren, Megan Weber, Ron Berman, Chalanda N. Evans, Christopher K. Snider, Eli Tsukayama, Christophe Van den Bulte, Kevin G. Volpp and Angela L. Duckworth
    Many Americans fail to get life-saving vaccines each year, and the availability of a vaccine for COVID-19 makes the challenge of encouraging vaccination more urgent than ever. We present a large field experiment (N = 47,306) testing 19 nudges delivered to patients via... View Details
    Keywords: Vaccination; COVID-19; Nudge; Influenza; Field Experiment; Health; Communication Strategy; Behavior
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    Milkman, Katherine L., Mitesh S. Patel, Linnea Gandhi, Heather N. Graci, Dena M. Gromet, Hung Ho, Joseph S. Kay, Timothy W. Lee, Modupe Akinola, John Beshears, Jonathan E. Bogard, Alison Buttenheim, Christopher F. Chabris, Gretchen B. Chapman, James J. Choi, Hengchen Dai, Craig R. Fox, Amir Goren, Matthew D. Hilchey, Jillian Hmurovic, Leslie K. John, Dean Karlan, Melanie Kim, David Laibson, Cait Lamberton, Brigitte C. Madrian, Michelle N. Meyer, Maria Modanu, Jimin Nam, Todd Rogers, Renante Rondina, Silvia Saccardo, Maheen Shermohammed, Dilip Soman, Jehan Sparks, Caleb Warren, Megan Weber, Ron Berman, Chalanda N. Evans, Christopher K. Snider, Eli Tsukayama, Christophe Van den Bulte, Kevin G. Volpp, and Angela L. Duckworth. "A Megastudy of Text-Based Nudges Encouraging Patients to Get Vaccinated at an Upcoming Doctor's Appointment." e2101165118. Proceedings of the National Academy of Sciences 118, no. 20 (May 18, 2021).
    • Web

    U.S. Cluster Mapping Project - Institute For Strategy And Competitiveness

    HBS ISC About Michael Porter About Michael Porter A Letter from Michael Porter Biography The Essential Porter Honors & Awards Affiliated Organizations & Institutions VBHCD Initiative Affiliated Organizations... Affiliated Organizations & Institutions ICHOM VBHCD... View Details
    • 23 Jul 2020
    • News

    The Long Game of Coronavirus Research

    • 24 Jul 2007
    • First Look

    First Look: July 24, 2007

    to use its limited resources focusing on Home Depot or find a new target to forward their cause. Purchase this case: http://www.hbsp.harvard.edu/b01/en/common/item_detail.jhtml?id=407097 Apollo Hospitals—First-World Health View Details
    Keywords: Martha Lagace
    • May 2024
    • Supplement

    DRSi (B)

    By: Richard S. Ruback and Royce Yudkoff
    Pre-Abstract: Instructors should consider the timing of making videos available to students, as they may reveal key case details.

    Abstract: In March of 2019, Jen Ransom Fuller purchased DRSi. DRSi, located in Bellevue, Washington, printed and reproduced... View Details
    Keywords: Acquisition; Small Business; Cost vs Benefits; Decisions; Business Education; Corporate Entrepreneurship; Leadership Style; Leading Change; Business or Company Management; Problems and Challenges; Health Pandemics; Selection and Staffing; Employee Relationship Management; Production; Logistics; Safety; Washington (state, US); United States
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    Ruback, Richard S., and Royce Yudkoff. " DRSi (B)." Harvard Business School Multimedia/Video Supplement 224-718, May 2024.
    • Web

    Events & Presentations - Institute For Strategy And Competitiveness

    competitiveness, strategies for business, creating shared value, and other topics. Recent & Upcoming Events November 16-18, 2022 November 2022 Strategy for Health Care Delivery HBS Campus, Boston, MA... View Details
    • 24 Feb 2022
    • News

    Want to Prevent the Next Hospital Bed Crisis? Enlist the SEC

    • February 2022
    • Case

    Cleveland Clinic Abu Dhabi (Abridged)

    By: Linda A. Hill and Emily Tedards
    In 2006, the Cleveland Clinic and Mubadala Investment Company partnered with a bold ambition to deliver world class healthcare in the United Arab Emirates. In 2015, after nearly a decade of planning and construction, Cleveland Clinic Abu Dhabi opened its doors. By... View Details
    Keywords: Organization Behavior; Culture; Alignment; Organizational Effectiveness; Purpose; Impact; Leadership Development; Diversity; Collaboration; Co-creation; Learning Organizations; Empowerment; Teams; Team Dynamics; Teamwork; Team Effectiveness; Trust; Talent; Talent Development And Retention; Psychological Safety; Organizational Evolution; Coaching; Board; Analytics; Innovation; Data; Data Visualization; Digital Technology; Digital; Customer Experience; Experimentation; Change Management; Data-driven Decision-making; Debates; Ecosystem; Partnership; Telemedicine; Sustainability; Global Organizations; Local; Hospital; Healthcare; United Arab Emirates; Health Care and Treatment; Partners and Partnerships; Globalization; Quality; Organizational Culture; Mission and Purpose; Innovation and Management; Information Technology; Joint Ventures; Leadership; Performance Effectiveness; Abu Dhabi; United Arab Emirates
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    Hill, Linda A., and Emily Tedards. "Cleveland Clinic Abu Dhabi (Abridged)." Harvard Business School Case 422-056, February 2022.
    • 15 Apr 2008
    • First Look

    First Look: April 15, 2008

    original operating model developed by Dr. Wheelis was one in which TBC was staffed by a large number of part-time clinicians, the "affiliate model." However, changes in the health care environment,... View Details
    Keywords: Martha Lagace
    • 01 Sep 2023
    • News

    Money Does Grow on (Family) Trees

    first genetic tests focused on ancestry were coming on the market. Though they were expensive and of limited utility, Cusenza saw the science rapidly improving, and he recognized opportunity not just in the health View Details
    Keywords: April White; Illustrations by Fabio Consoli; News, Library, Internet, and Other Services; Information
    • 16 Nov 2021
    • HBS Case

    How a Company Made Employees So Miserable, They Killed Themselves

    employee departures. Company officials kept a careful count of departing workers and doled out bonuses to managers based on the number of workers in their groups that left. Managers and workers alike exhibit stress Many managers,... View Details
    Keywords: by Michael Blanding
    • 09 Jun 2015
    • First Look

    First Look: June 9, 2015

    allowed by health authorities. Yet caries remained a significant threat to public health in many countries, both developing and developed. As Suzan Harrison, Colgate's president of Oral Care, prepared to... View Details
    Keywords: Sean Silverthorne
    • October 1982 (Revised May 1992)
    • Case

    Johnson & Johnson: The Tylenol Tragedy

    By: Stephen A. Greyser
    In October 1982, Johnson & Johnson was confronted with a major crisis when seven deaths were attributed to poisoned Tylenol. The case reviews the facts as known a week after the incident occurred, and raises a wide range of questions regarding consumer behavior,... View Details
    Keywords: Consumer Behavior; Corporate Social Responsibility and Impact; Competitive Strategy; Crisis Management; Health Care and Treatment; Pharmaceutical Industry
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    Greyser, Stephen A. "Johnson & Johnson: The Tylenol Tragedy." Harvard Business School Case 583-043, October 1982. (Revised May 1992.)
    • Web

    Systems Integration - Institute For Strategy And Competitiveness

    HBS ISC Health Care Health Care Value-Based Health Care View Details
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