Publications

November 1994
Case

Pilkington Float Glass--1955

By: Kim B. Clark

The case examines the development of the float glass process at Pilkington in the mid-1950s. Pilkington has pursued the development of a radically new process for flat glass production, but has experienced serious problems at each stage of development. The senior... View Details

Keywords: Transformation; Decision Choices and Conditions; Technological Innovation; Product Development; Research and Development; Commercialization; Technology

September 1993 (Revised June 1994)
Supplement

Hewlett-Packard: Singapore (B)

By: Dorothy A. Leonard

Discusses the printer Hewlett-Packard has developed. View Details

Keywords: Risk and Uncertainty; Product Development; Research; Marketing; Market Entry and Exit; Computer Industry; Manufacturing Industry; Singapore

June 2005 (Revised August 2006)
Case

Ducati Corse

By: Francesca Gino and Andrew P. McAfee

Ducati Corse, the racing arm of Ducati Motorcycles, has entered the Moto GP circuit with a completely new bike. This bike was designed and tested using a great deal of information technology. After a very successful initial season, the Ducati Moto GP team sees... View Details

Keywords: Design; Business Strategy; Product Marketing; Information Technology; Performance Improvement; Change Management; Research and Development; Motorcycle Industry; Italy

October 2009 (Revised August 2014)
Case

Tengion: Bringing Regenerative Medicine to Life

By: Elie Ofek and Polly Ross Ribatt

Tengion is a young biotech company that is at the frontier of regenerative medicine—a nascent field that seeks to promote the creation of new cells and tissue to repair or replace tissue or organ function lost due to age, disease, damage, or congenital defects. In late... View Details

Keywords: Decision Choices and Conditions; Financial Crisis; Entrepreneurship; Health Care and Treatment; Technological Innovation; Product Launch; Product Development; Research and Development; Biotechnology Industry; United States

January 2023
Case

Cleave Therapeutics: Taking a Risk on Oncology Drug Discovery

By: Regina Herzlinger and Brian Walker

What should a successful executive (HBS Baker Scholar) assess as her next move as the CEO of a firm with a promising and yet uncertain new drug? Amy Burroughs’ mandate to successfully commercialize Cleave Therapeutics’ drug for a cancer with no current successful... View Details

Keywords: Product Development; Leadership; Health Testing and Trials; Research and Development; Risk and Uncertainty; Financial Condition; Partners and Partnerships; Pharmaceutical Industry

December 2008 (Revised October 2013)
Case

Amylin Pharmaceuticals: Diabetes and Beyond (A)

By: Richard G. Hamermesh and Rachel Gordon

Ginger Graham, CEO of Amylin Pharmaceuticals, joined the company with the expectation of taking the company's signature drug, Symlin, to market. However, unforeseen regulatory challenges have put the approval process in jeopardy. At the same time, the company has a... View Details

Keywords: Regulations; Drug Regulations; Symlin; Negotiation; Governing Rules, Regulations, and Reforms; Resource Allocation; Negotiation Deal; Product Development; Research and Development; Commercialization; Pharmaceutical Industry; United States

winter 2001
Article

Product-Development Practices That Work: How Internet Companies Build Software

By: A. D. MacCormack

Keywords: Product; Research and Development; Internet and the Web; Applications and Software

Profile

Kaki Ettinger

how I could make the greatest contribution. I came to HBS to discover and understand the different paths in this sector for someone with an analytical mind, a deep interest in technology, and a passion for storytelling and the creative aspects of View Details

Keywords: Entertainment / Media; Technology; Entrepreneurship

November 2023 (Revised April 2024)
Case

BiomX: Bringing Phage Back to the Stage

By: Paul A. Gompers, Elie Ofek, Orna Dan and Emilie Billaud

In the spring of 2023, and following the favorable results of a trial involving its phage cocktail for treating lung infections among cystic fibrosis (CF) patients, the leadership of BiomX had several critical issues to wrestle with. First, given its precarious... View Details

Keywords: Working Capital; Financing and Loans; Health Testing and Trials; Product Development; Research and Development; Science-Based Business; Commercialization; Biotechnology Industry; Pharmaceutical Industry

September 2011
Teaching Note

Tengion: Bringing Regenerative Medicine to Life (TN)

By: Elie Ofek and Natalie Kindred

Teaching Note for 510031. View Details

Keywords: Partners and Partnerships; Production; Marketing; Cash; Health Care and Treatment; Medical Specialties; Research and Development; Biotechnology Industry

28 Nov 2007
Research & Ideas

B2B Branding: Does it Work?

Interbrand's 10 most valuable global brands, we find Microsoft, Intel, IBM, and GE. All generate far more B2B revenues than sales to end consumers. An HBS research team recently conducted a study of top B2B global brands. These brands... View Details

Keywords: by John Quelch; Consumer Products

01 Jun 2015
News

The End of Cows?

Price is a market barrier for lab-grown beef, with production costs currently exceeding 250,000 euros per burger. (Photo courtesy of Cultured Beef) Price is a market barrier for lab-grown beef, with View Details

Keywords: Jason Feifer; Scientific Research and Development Services; Scientific Research and Development Services; Scientific Research and Development Services

April 1993 (Revised November 1994)
Case

Chiron Corp.

By: Steven C. Wheelwright

Pablo Valenzuela, vice president of R&D at Chiron Corp., faces several choices for how to allocate scarce resources across several promising projects. These choices will determine Chiron's position in several emerging biotechnology and diagnostic markets, including... View Details

Keywords: Health Testing and Trials; Research and Development; Failure; Business Strategy; Joint Ventures; Strategic Planning; Opportunities; Product Development; Biotechnology Industry; California

31 May 2023
Research & Ideas

With Predictive Analytics, Companies Can Tap the Ultimate Opportunity: Customers’ Routines

service—be it exclusive viewing or a specific product or service sale—to draw in more routine customers. More research on how that may work best is needed, Ascarza says. Not just companies The method of... View Details

Keywords: by Rachel Layne; Transportation

October 2019 (Revised April 2020)
Background Note

Note on Funding Deep Tech Startups

By: Karim Lakhani, Peter Barrett and Noubar Afeyan

This Background Note provides essential information on funding deep technologies—those technologies that were inherently capital intensive, time consuming, risky, and potentially disruptive. Both dilutive and non-dilutive sources of investment are highlighted, along... View Details

December 2002
Article

Knowledge Seeking and Location Choice of Foreign Direct Investment in the United States

By: Juan Alcacer and Wilbur Chung

To what extent do firms go abroad to access technology available in other locations? This paper examines whether and when state technical capabilities attract foreign investment in manufacturing from 1987-1993. We find that on average state R&D intensity does not... View Details

Keywords: Knowledge Acquisition; Foreign Direct Investment; Research and Development; Information Technology; Production; Geographic Location; United States