Publications

07 Dec 1999
Research & Ideas

Henry Heinz and Brand Creation in the Late Nineteenth Century

strategic rationale of branding and its importance to competing effectively on the demand side of the economy. In a young market, he realized, consumers had to be able to identify a particular product's source, functional attributes, and perceived View Details

Keywords: by Nancy F. Koehn

February 2022
Case

Cleveland Clinic Abu Dhabi: Leading Through the Fog of the COVID-19 Pandemic

By: Linda A. Hill and Emily Tedards

As COVID-19 began to take lives, destroy healthcare systems, and shut down economies across the globe, Dr. Rakesh Suri, Chief Executive Officer of Cleveland Clinic Abu Dhabi, and his executive team adapted their leadership to instill the new levels of agility and... View Details

November 2009 (Revised August 2010)
Case

NovoCure Ltd.

By: William A. Sahlman and Sarah Flaherty

Venture capitalist William Doyle must raise $35 million for a portfolio company with a promising, novel cancer therapy, just as global capital markets are imploding in the fall of 2008. NovoCure, Ltd., has developed an electrical-field-based therapy, called Tumor... View Details

Keywords: Financial Crisis; Entrepreneurship; Venture Capital; Investment; Health Care and Treatment; Health Testing and Trials; Technological Innovation; Financial Services Industry

January 2018
Article

Innovation Incentives and Biomarkers

By: Ariel Dora Stern, Brian M. Alexander and Amitabh Chandra

Previously, we have discussed the importance of economic incentives in shaping markets for precision medicines. Here we consider incentives for biomarker development, including discovery and establishment. Biomarkers can reveal valuable information regarding diagnosis... View Details

Keywords: Health Care and Treatment; Innovation and Invention; Research and Development; Markets

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May 2011
Article

Nonsimultaneous Chains and Dominos in Kidney Paired Donation—Revisited

By: Itai Ashlagi, Duncan S. Gilchrist, Alvin E. Roth and Michael A. Rees

Since 2008 kidney exchange in America has grown in part from the incorporation of non-directed donors in transplant chains rather than simple exchanges. It is controversial whether these chains should be performed simultaneously ("domino paired donation," DPD) or... View Details

Keywords: ABO Incompatibility; Allosensitization; Paired Kidney Exchange; Regional Sharing; Simulation Models; Transplantation Policy; Health Care and Treatment; Supply Chain; Risk and Uncertainty; Logistics; United States

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06 Aug 2013
First Look

First Look: August 6

document sources of value creation in mergers by analyzing novel data on the quality and price of goods sold by merging firms. When two competitors in a product market merge, their products converge in quality, and prices fall relative to... View Details

Keywords: Anna Secino

March 2022
Article

Where to Locate COVID-19 Mass Vaccination Facilities?

By: Dimitris Bertsimas, Vassilis Digalakis Jr, Alexander Jacquillat, Michael Lingzhi Li and Alessandro Previero

The outbreak of COVID-19 led to a record-breaking race to develop a vaccine. However, the limited vaccine capacity creates another massive challenge: how to distribute vaccines to mitigate the near-end impact of the pandemic? In the United States in particular, the new... View Details

Keywords: Vaccines; COVID-19; Health Care and Treatment; Health Pandemics; Performance Effectiveness; Analytics and Data Science; Mathematical Methods

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23 May 2011
Research & Ideas

Corporate Sustainability Reporting: It’s Effective

change in the social awareness of investors in the past decade. "The number of investors who care about this kind of performance has increased dramatically in the last 10 years," Serafeim says. "Right now those investors have about $5... View Details

Keywords: by Michael Blanding

08 Nov 2024
Op-Ed

How Private Investors Can Help Solve Africa's Climate Crisis

has quantified the reduction in health care costs from bad outcomes related to automobile pollution. And they have also quantified the time benefit, finding that the BRT so far has reduced a 90-minute trip... View Details

Keywords: by John Macomber; Green Technology; Energy

24 Mar 2022
Research & Ideas

Why Cutting Jobless Aid Isn't the Answer to Worker Shortages

16,000 people unemployed at the end of April 2021 who received federal benefits through the CARES Act of 2020. The authors analyzed anonymized bank transaction data from January 1 through September 17, 2021. Researchers then compared the... View Details

Keywords: by Rachel Layne

September 2024
Case

Myeloma Investment Fund

By: Kyle Myers and Scott Sawaya

This case explores a critical decision facing the Myeloma Investment Fund (MIF) as it evaluates two investment opportunities aimed at accelerating a cure for multiple myeloma.

The MIF, a venture philanthropy fund, must choose between two distinct paths. One... View Details

Keywords: Venture Philanthropy; Biomedical Research; Investing For Impact; Innovation ＆ Entrepreneurship; Venture Capital; Science-Based Business; Philanthropy and Charitable Giving; Decision Making; Health Care and Treatment; Biotechnology Industry; Pharmaceutical Industry

December 5, 2024
Article

A Consensus Definition of Creativity in Surgery: A Delphi Study Protocol

By: Alex Thabane, Tyler McKechnie, Phillip Staibano, Vikram Arora, Goran Calic, Jason W. Busse, Sameer Parpia and Mohit Bhandari

Introduction
Clear definitions are essential in science, particularly in the study of abstract phenomena like creativity. Due to its inherent complexity and domain-specific nature, the study of creativity has been complicated, as evidenced by the various... View Details

Keywords: Creativity; Health Care and Treatment; Outcome or Result; Measurement and Metrics

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May 2023 (Revised June 2023)
Supplement

Novartis (B): Reimagining Medicine

By: Ramon Casadesus-Masanell, Claudio Feser, Karolin Frankenberger and David Redaschi

This case unfolds around the first-ever approved personalized cancer treatment, how Novartis wrapped it into a new business model design, and how Novartis scaled it. Novartis — one of the largest pharmaceutical companies in the world — is, among other ventures,... View Details

Keywords: Health Care and Treatment; Business Model; Production; Business Strategy; Pharmaceutical Industry

Article

Managing the Use and Dissemination of Information about Biomarkers: The Importance of Incentive Structures.

By: Ariel Dora Stern

The use of biomarkers holds great promise for the development of new therapeutics and the acceleration of clinical research. However, biomarkers must be validated—a complex and costly endeavor. Importantly, biomarker validation is meaningfully shaped by economic and... View Details

Keywords: Biomarkers; Information Management; Health Care and Treatment; Motivation and Incentives

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November 1978 (Revised October 1989)
Case

Amicon Corp. (B)

Details the negotiation between Amicon and three potential licensees, Jackson, Maynard-Smith and Behrstein. View Details

Keywords: Technology; Patents; Negotiation Process; Negotiation Participants; Health Care and Treatment; Biotechnology Industry

November 24, 2020
Article

4 Strategies to Make Telehealth Work for Elderly Patients

By: Umar Ikram, Susanna Gallani, Jose F. Figueroa and Thomas W. Feeley

As providers have ramped up their use of telehealth during the COVID-19 pandemic, one group—the elderly—has experienced particular challenges in adopting the technologies. This article describes the strategies four innovative provider organizations have used to engage... View Details

Keywords: Telehealth; Health Pandemics; Health Care and Treatment; Internet and the Web; Age; Technology Adoption; Strategy

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August 2021
Teaching Note

IBM Watson at MD Anderson Cancer Center

By: Shane Greenstein and Mel Martin

Teaching Note for HBS Case No. 621-022. View Details

Keywords: Decision Making; Technological Innovation; Innovation Strategy; Knowledge Management; Knowledge Use and Leverage; Operations; Failure; Information Technology; Applications and Software; Health Care and Treatment; Product Development; Health Industry; Health Industry; Health Industry; United States; Houston; Texas