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June 2021
Case

uBiome

By: Thomas R. Eisenmann and Olivia Graham

uBiome provided clinical tests that sequenced the DNA of human microbiome samples, providing data on health conditions directly to consumers or to prescribing physicians. Founded in 2012, the San Francisco-based startup raised $105 million from top-tier venture capital... View Details

Keywords: Business Startups; Crime and Corruption; Insolvency and Bankruptcy

March 2017
Article

Variation in the Cost of Care for Primary Total Knee Arthroplasties

By: Derek A. Haas and Robert S. Kaplan

The study examined the cost variation across 29 high-volume U.S. hospitals for delivering a primary total knee arthroplasty without major complicating conditions. Hospital and physician personnel costs were calculated using time-driven activity-based costing.... View Details

Keywords: Cost Management; Performance Productivity; Health Care and Treatment; Health Industry

September 2013 (Revised August 2014)
Case

Claritas Genomics

By: Robert F. Higgins and Matthew Preble

Claritas Genomics was formed in January 2013 when BCH spun out its Genetics Diagnostic Lab into a fully commercial entity. Claritas offered over 100 genomic tests to detect a range of conditions, including autism and intellectual disabilities, and was developing new... View Details

December 2009 (Revised September 2024)
Case

Phreesia: The Patient Intake Company

By: Regina E. Herzlinger, Sunaina Yarlagadda and Brian L. Walker

How should the co-founders of an organization that provides patient sign-in and billing services scale their company after five years of successfully targeting small private physician practices? Phreesia had deployed a direct mail and sales force strategy that resulted... View Details

Keywords: Advertising; Social Entrepreneurship; Revenue; Health Care and Treatment; Health Industry

Article

Medical Group Structural Integration May Not Ensure That Care Is Integrated, From The Patient's Perspective

By: Michaela J. Kerrissey, Jonathan Clark, Mark Friedberg, Wei Jiang, Ashley Kay Fryer, Molly Frean, Stephen Shortell, Patricia Ramsay, Lawrence Casalino and Sara J. Singer

Structural integration is increasing among medical groups, but whether these changes yield care that is more integrated remains unclear. We explored the relationships between structural integration characteristics of 144 medical groups and perceptions of integrated... View Details

Keywords: Integration; Health Care Delivery; Organization Structure; Organizational Structure; Health Care and Treatment; Perception; Perspective; Health Industry; United States

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15 Mar 2007
Working Paper Summaries

Initiating Divergent Organizational Change: The Enabling Role of Actors’ Social Position

Keywords: by Julie Battilana

October 1997 (Revised March 2000)
Case

Oxford Health Plans: Specialty Management (A)

By: James L. Heskett, Jody H. Gittell and James Slayton

Describes an innovative approach to organizing health care proposed by Oxford CEO Steve Wiggins. Wiggins contends that the primary care physician "gatekeeper" model typically used by health maintenance organizations to control access to and coordinate specialist care... View Details

Keywords: Business Model; Groups and Teams; Innovation and Management; Medical Specialties; Health Care and Treatment; Cooperation; Management Teams; Health Industry; United States

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March 2013
Other Article

Redesigning Primary Care: A Strategic Vision to Improve Value by Organizing Around Patients' Needs

By: Michael E. Porter, Erika A. Pabo and Thomas H. Lee

Primary care in the United States currently struggles to attract new physicians and to garner investments in infrastructure required to meet patients' needs. We believe that the absence of a robust overall strategy for the entire spectrum of primary care is a... View Details

Keywords: Health

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July 2000 (Revised November 2001)
Case

Catalyst Medical Solutions

By: Amy C. Edmondson, Richard M.J. Bohmer and Naomi Atkins

Faced with a drop in the NASDAQ, four eHealth entrepreneurs must decide between two distribution strategies for their new company's technology. The team, comprised of three full-time resident physicians and an MBA, has developed software to enable electronic... View Details

Keywords: Product Development; Health Care and Treatment; Distribution; Strategy; Venture Capital; Applications and Software; Partners and Partnerships; Borrowing and Debt; Information Technology Industry; Service Industry

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19 May 2015
First Look

First Look: May 19

Publications May 2015 Cambridge University Press Land Bargains and Chinese Capitalism: The Politics of Property Rights under Reform By: Rithmire, Meg Abstract—Land reforms have been critical to the development of Chinese capitalism over the last several decades, yet... View Details

Keywords: Sean Silverthorne

2021
Working Paper

Regulatory Approval and Expanded Market Size

By: Benjamin Berger, Amitabh Chandra and Craig Garthwaite

Regulatory review of new medicines is often viewed as a hindrance to innovation by increasing the hurdle to bring products to market. However, a more complete accounting of regulation must also account for its potential market expanding effects through quality... View Details

Keywords: New Medicines; Regulatory Approval; Health Care and Treatment; Research and Development; Governing Rules, Regulations, and Reforms; Markets; Expansion; Pharmaceutical Industry

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12 Mar 2019
First Look

New Research and Ideas, March 12, 2019

Abstract—Objectives: To apply time-driven activity-based costing (TDABC) methodology to determine emergency medicine physician documentation costs with and without scribes. Methods: Two research assistants shadowed attending View Details

Keywords: Dina Gerdeman

May 2021
Case

Inclusive Innovation at Mass General Brigham

By: Katherine Baldiga Coffman and Olivia Hull

Massachusetts General Brigham (MGB) Chief Innovation Officer Christopher Coburn had overseen a period of exciting transformation and growth in healthcare innovation at MGB. In November 2019, the health system was the largest recipient of National Institutes of Health... View Details

Article

A Cost Comparison of Cataract Surgeries in Three Countries—United States, India, and Nepal

By: Jiayin Xue, John Hinkle, Mary-Grace Reeves, Luo Luo Zheng, Vengadesan Natarajan, Shyam Vyas, Radhika Upreti Oli, Matt Oliva, Robert S. Kaplan, Arnold Milstein, Geoff Tabin, Jeffrey L. Goldberg and Kevin Schulman

U.S.-based cataract surgeries are costly compared with those performed in high-quality Indian and Nepalese eye centers. The authors used time-driven activity-based costing to evaluate phacoemulsification surgery across four sites: a U.S.-based academic hospital... View Details

Keywords: Time-Driven Activity-Based Costing; Cost Accounting; Health Care and Treatment; Health Industry; India; Nepal; United States

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August 2016
Article

Value-Based Breast Cancer Care: A Multidisciplinary Approach for Defining Patient-Centered Outcomes

By: Fayanju M. Oluwadamilola, Tinisha L. Mayo, Tracy E. Spinks, Seohyun Lee, Carlos H. Barcenas, Benjamin D. Smith, Sharon H. Giordano, Rosa F. Hwang, Richard A. Ehlers, Jesse C. Selber, Ronald Walters, Debu Tripathy, Kelly K. Hunt, Thomas A. Buchholz, Thomas W. Feeley and Henry M. Kuerer

Purpose. Value in healthcare—i.e., patient-centered outcomes achieved per healthcare dollar spent—can define quality and unify performance improvement goals with health outcomes of importance to patients across the entire cycle of care. We describe the process... View Details

Keywords: Health Disorders; Value; Health Care and Treatment; Performance Improvement; Health Industry

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2011
Working Paper

The Flexible Substitution Logit: Uncovering Category Expansion and Share Impacts of Marketing Instruments

By: Qiang Liu, Thomas J. Steenburgh and Sachin Gupta

Different instruments are relevant for different marketing objectives (category demand expansion or market share stealing). To help brand managers make informed marketing mix decisions, it is essential that marketing mix models appropriately measure the different... View Details

Keywords: Decision Choices and Conditions; Forecasting and Prediction; Investment; Brands and Branding; Marketing Strategy; Demand and Consumers; Mathematical Methods

Article

Use of Crowd Innovation to Develop an Artificial Intelligence-Based Solution for Radiation Therapy Targeting

By: Raymond H. Mak, Michael G. Endres, Jin Hyun Paik, Rinat A. Sergeev, Hugo Aerts, Christopher L. Williams, Karim R. Lakhani and Eva C. Guinan

Importance: Radiation therapy (RT) is a critical cancer treatment, but the existing radiation oncologist work force does not meet growing global demand. One key physician task in RT planning involves tumor segmentation for targeting, which requires substantial... View Details

Keywords: Crowdsourcing; AI Algorithms; Health Care and Treatment; Collaborative Innovation and Invention; AI and Machine Learning

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09 Apr 2013
First Look

First Look: April 9

Cases & Course Materials Harvard Business School Case 612-016 Lowell General Physician Hospital Organization This case focuses on the Alternative Quality Contract (AQC), a novel payment program designed to incentivize providers to... View Details

Keywords: Sean Silverthorne

2019
Chapter

Characterizing the Drug Development Pipeline for Precision Medicines

By: Amitabh Chandra, Craig Garthwaite and Ariel Dora Stern

BOOK ABSTRACT: Personalized and precision medicine (PPM)—the targeting of therapies according to an individual’s genetic, environmental, or lifestyle characteristics—is becoming an increasingly important approach in health care treatment and prevention. The advancement... View Details

Keywords: Healthcare; Precision Medicine

10 Oct 2007
First Look

First Look: First Look: October 10

genomics, diagnostic testing, and targeted therapies. They say that medical schools and physician organizations must become committed advocates of personalized medicine so that patients and the medical industry can get all the benefits it... View Details

Keywords: Martha Lagace

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