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November 2024
Supplement

AlphaGo (C): Birth of a New Intelligence

By: Shikhar Ghosh and Shweta Bagai

This case, the final of a three-part series, explores DeepMind's pivotal transition from mastering games to solving real-world scientific challenges. In December 2020, DeepMind's AI system AlphaFold 2 achieved a breakthrough by solving protein folding—a 50-year-old... View Details

Keywords: Autonomy; Deep Learning; Drug Discovery; Healthcare Innovation; Neural Networks; Scientific Research; Technology Startup; AI and Machine Learning; Technological Innovation; Research and Development; Business Model; Business Strategy; Open Source Distribution; Technology Industry; United States

Article

One Obstacle to Curing Cancer: Patient Data Isn't Shared

By: Richard G. Hamermesh and Kathy Giusti

Precision Medicine requires large datasets to identify the mutations that lead to various cancers. Currently, genomic information is hoarded in fragmented silos within numerous academic medical centers, pharmaceutical companies, and some disease-based foundations. For... View Details

Keywords: Healthcare; Technological And Scientific Innovation; Cancer Care In The U.S.; Cancer Treatment; Precision Medicine; Personalized Medicine; Data Sharing; Technological Innovation; Analytics and Data Science; Health Disorders; Medical Specialties; Research and Development; Customization and Personalization; Health Industry; United States

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July 2022 (Revised February 2024)
Teaching Note

The DivaCup: Navigating Distribution and Growth

By: Ayelet Israeli

Teaching Note for HBS Case No. 519-055. When the mother-daughter founders of DivaCup set out with a mission to disrupt the menstrual care industry with an innovative product form, they initially struggled to gain legitimacy and convince retailers to carry their unique... View Details

March 2019 (Revised April 2021)
Case

The DivaCup: Navigating Distribution and Growth

By: Ayelet Israeli

When the mother-daughter founders of DivaCup set out with a mission to disrupt the menstrual care industry with an innovative product form, they initially struggled to gain legitimacy and convince retailers to carry their unique product. Fifteen years later, the... View Details

September 2000 (Revised June 2002)
Supplement

Overview of E-Business Pricing Models

By: Lynda M. Applegate, W. Earl Sasser and Kristin Kohler

Supplements National Logistics Management. View Details

Keywords: Internet and the Web; Price; Business Model; Information Technology Industry

February 2016
Case

Express Scripts: Promoting Prescription Drug Home Delivery (A)

By: John Beshears, Patrick Rooney and Jenny Sanford

The pharmacy benefit manager (PBM) sector processes prescription drug claims on behalf of companies that offer a prescription drug benefit to their employees. This case follows Bob Nease, Chief Scientist at Express Scripts, as he considers methods to promote home... View Details

Keywords: Pharmaceuticals; Prescription Drugs; Pharmacy Benefit Manager; PBM; Healthcare; Behavioral Economics; Choice Architecture; Active Choice; Service Delivery; Decision Choices and Conditions; Health Care and Treatment; Order Taking and Fulfillment; Compensation and Benefits; Pharmaceutical Industry

April 2017
Supplement

Imprimis (B)

By: Ramon Casadesus-Masanell, Karen Elterman and Marc Appel

This case is a supplement to Imprimis (A). It describes the company’s decision to enter into the pharmaceutical compounding business in 2013–2014. Imprimis purchased a compounded ophthalmological medication called Dropless Therapy, which was injected into patients’... View Details

Keywords: Healthcare; Drug Compounding; Drug Development; Pharmaceuticals; Small Business; Decision-making, Business Model; Mark Baum; Imprimis; Decision Making; Strategy; Health Care and Treatment; Policy; Pharmaceutical Industry; United States

April 1989 (Revised March 1990)
Case

Burlington Northern (B)

By: Janice H. Hammond

Describes the experiences of a seasoned Burlington Northern (BN) sales representative after the introduction of ShipSmart, a decision support system developed by the BN to help its employees and customers analyze logistics problems. After a brief description of a... View Details

Keywords: Change Management; Expansion; Rail Transportation; Logistics; Distribution Channels; Truck Transportation; Innovation and Invention; Sales; Rail Industry; United States

February 2015 (Revised November 2015)
Supplement

Building an Integrated Biopharma Company: Crucell (B)

By: Richard G. Hamermesh, Marianne Van Der Steen and Susan Harmeling

The Crucell (B) case updates events at Crucell since 2009. In September, 2009, Johnson & Johnson acquired 18% of Crucell for $400 million. This investment was part of a business development deal. Subsequently, in 2012, Johnson & Johnson acquired Crucell for $2.8... View Details

Keywords: Biotechnology; Biopharmacy Company; Licensing Agreements In Biopharmacy; Licensing; Human Cell-line Technology; Vaccine; Healthcare Innovation; Global Health; Entrepreneurship; Health Care and Treatment; Acquisition; Innovation and Invention; Biotechnology Industry; Biotechnology Industry

January 2014
Teaching Plan

MedImmune Ventures

By: Richard Hamermesh and Andrew Otazo

"MedImmune Ventures" highlights the problems faced by corporate venture capital firms, the challenges of investing in early-stage healthcare, and the difficulty of operating in distant markets. View Details

Keywords: MedImmune Ventures; NeuProtect; Corporate Venture Capital; Ron Laufer; Australia; Starfish Ventures; AstraZeneca; MEVE; Healthcare; Startup; Venture Capital; Business Startups; Health Industry; Australia; United States

15 Jul 2013
Research & Ideas

Five Imperatives for Improving Health Care

conference and survey from Harvard's business and medical schools may prove particularly timely. Delivered by the Forum on Healthcare Innovation, which was formed last year with encouragement from the respective deans of the two... View Details

Keywords: by Carmen Nobel; Health

October 2015 (Revised September 2016)
Technical Note

Flight: Now without Humans Aboard

By: Mitchell Weiss, Karim Lakhani, HT Kung and Kerry Herman

This note provides an overview of the unmanned aerial vehicles (UAVs, or drones) industry in September 2015. UAVs offered many potential applications in industries as diverse as aerial imaging and photography, agriculture, construction, infrastructure inspection and... View Details

Keywords: Public Entrepreneurship; Drones; Entrepreneurship; Business Startups; Product Design; Research and Development; Technological Innovation; Rights; Ethics; Strategy; Transportation Networks; Market Entry and Exit; Innovation and Management; European Union; Asia; United States

August 2017
Case

RoboTech: Storming into the U.S. Market

By: Christopher A. Bartlett, Rachel Gordon and John J. Lafkas

This case describes the challenges facing the CEO of a small, Singapore-based industrial robotics company that decides to diversify away from its core industrial robot business by leveraging its expertise into the medical-devices industry. It launches an innovative... View Details

Keywords: Market Entry and Exit; Diversification; Product Launch; Competitive Strategy; Globalized Firms and Management; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; Singapore; United States

July 2019 (Revised May 2020)
Case

AT&T, Retraining, and the Workforce of Tomorrow

By: William R. Kerr, Joseph B. Fuller and Carl Kreitzberg

By the late 2000s, rapid changes in the telecommunications industry forced AT&T’s management team to take on a task that CEO Randall Stephenson called the “biggest logistical challenge” they had ever seen: retraining 100,000 workers by 2020. In 2012, internal company... View Details

August 2024
Case

Coca Cola İçecek—Managing a Sudden Turbulence

By: Felix Oberholzer-Gee, Namrata Arora and Gizem Cihan Dincsoy

In November 2021, Kerem Kerimoğlu, Coca Cola İçecek (CCI) Group Supply Chain Development Director, is alarmed by a news headline revealing a shortage of Turkish truck drivers impacting Europe. This crisis quickly affects CCI's distribution as third-party logistics... View Details

Keywords: Business Strategy; Logistics; Supply Chain Management; Crisis Management; Distribution; Consumer Products Industry; Consumer Products Industry; Turkey; Central Asia; Middle East

Teaching Interest

MBA Elective Curriculum: Mastering Strategy Execution

By: Robert Simons

This course teaches future general managers, entrepreneurs, and consultants how to execute strategy and deliver results. Using readings, exercises, and case studies in industries as diverse as healthcare space exploration, and software development, you will learn to... View Details

February 2015 (Revised November 2015)
Case

Building an Integrated Biopharma Company: Crucell (A)

By: Richard G. Hamermesh, Marianne Van Der Steen and Susan S. Harmeling

By 2009, Crucell had become the largest biopharma company in the Netherlands and a symbol of national pride. The case traces the evolution of the company from a University spin-off into a fully-integrated company. Crucell's success, particularly in the vaccine space,... View Details

Keywords: Biotechnology; Biopharmacy Company; Licensing; Licensing Agreements In Biopharmacy; Human Cell-line Technology; Vaccine; Healthcare Innovation; Global Health; Partners and Partnerships; Entrepreneurship; Growth and Development Strategy; Biotechnology Industry; Biotechnology Industry; Netherlands

June 2006 (Revised September 2006)
Case

Tech Data Corporation

Tech Data is a global supplier of logistics management services and one of the world's largest distributors of information technology equipment. Operational execution is key for the company, which has gross margins in the 5% range. At the end of 2005, the company had... View Details

Keywords: Competition; Information Infrastructure; Operations; Growth and Development Strategy

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August 1998
Case

HIMSCORP, Inc.

By: William A. Sahlman, Michael J. Roberts and Laurence E. Katz

Himscorp is an industry consolidation of records storage companies providing management and retrieval services of active medical records to healthcare institutions. Kent Dauten, a former general partner at Madison Dearborn Partners with 15 years of venture capital and... View Details

Keywords: Value Creation; Initial Public Offering; Business Exit or Shutdown; Business Growth and Maturation; Decision Choices and Conditions; Consolidation; Information Industry

August 2019
Case

Simón Cohen at Henco: Sustaining 'High Performance, Happy People'

By: Francesca Gino, Jeff Steiner, Arianna Camacho and Paul Green

Simón Cohen—Founder of Henco Logistics—transformed a small Mexican logistics company into a major player within the industry. Cohen credits the firm’s focus on employee happiness as the key ingredient to its success, an approach he developed following a personal... View Details

Keywords: Work/life Balance; Growth Strategy; Corporate Culture; Motivation; Values; Authentic Leadership Development; Leadership; Personal Development and Career; Motivation and Incentives; Values and Beliefs; Service Operations; Organizational Culture; Growth and Development Strategy; Service Industry

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