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      • July 2023
      • Case

      DayTwo: Going to Market with Gut Microbiome (Abridged)

      By: Ayelet Israeli
      DayTwo is a young Israeli startup that applies research on the gut microbiome and machine learning algorithms to deliver personalized nutritional recommendations to its users in order to minimize blood sugar spikes after meals. After a first year of trial rollout in... View Details
      Keywords: Business Startups; AI and Machine Learning; Nutrition; Market Entry and Exit; Product Marketing; Distribution Channels
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      Israeli, Ayelet. "DayTwo: Going to Market with Gut Microbiome (Abridged)." Harvard Business School Case 524-015, July 2023.
      • 2023
      • Article

      Evidence from the First Shared Medical Appointments (SMAs) Randomised Controlled Trial in India: SMAs Increase the Satisfaction, Knowledge, and Medication Compliance of Patients with Glaucoma

      By: Nazlı Sönmez, Kavitha Srinivasan, Rengaraj Venkatesh, Ryan W. Buell and Kamalini Ramdas
      In Shared Medical Appointments (SMAs), patients with similar conditions meet the physician together and each receives one-on-one attention. SMAs can improve outcomes and physician productivity. Yet privacy concerns have stymied adoption. In physician-deprived nations,... View Details
      Keywords: Health Care and Treatment; Customer Satisfaction; Outcome or Result; India
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      Sönmez, Nazlı, Kavitha Srinivasan, Rengaraj Venkatesh, Ryan W. Buell, and Kamalini Ramdas. "Evidence from the First Shared Medical Appointments (SMAs) Randomised Controlled Trial in India: SMAs Increase the Satisfaction, Knowledge, and Medication Compliance of Patients with Glaucoma." e0001648. PLoS Global Public Health 3, no. 7 (2023).
      • July 2023
      • Case

      Moderna: Everything, Everywhere, All at Once

      By: Satish Tadikonda, Shikhar Ghosh and William Marks
      Coming out of the COVID-19 pandemic, Moderna was riding the successes of developing a vaccine in record time and helping stem the tide of the crisis. However, the company had grown at an incredible rate, more than doubled its number of employees, and had to put on hold... View Details
      Keywords: Health Pandemics; Selection and Staffing; Growth Management; Management Succession; Retirement; Technological Innovation; Corporate Strategy; Biotechnology Industry
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      Tadikonda, Satish, Shikhar Ghosh, and William Marks. "Moderna: Everything, Everywhere, All at Once." Harvard Business School Case 824-021, July 2023.
      • July 2023
      • Article

      Deep Responsibility and Irresponsibility in the Beauty Industry

      By: Geoffrey Jones
      This article employs the concept of deep responsibility to assess the social responsibility of the beauty industry over time. It shows that many of today’s problems with the industry have deep historical roots. Products have too many ingredients that are potential... View Details
      Keywords: Business History; Corporate Social Responsibility and Impact; Beauty and Cosmetics Industry
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      Jones, Geoffrey. "Deep Responsibility and Irresponsibility in the Beauty Industry." Entreprises et histoire 111, no. 2 (July 2023): 113–125.
      • Summer 2023
      • Article

      Do Policies to Increase Access to Treatment for Opioid Use Disorder Work?

      By: Eric Barrette, Leemore S. Dafny and Karen Shen
      Even among commercially insured individuals, opioid use disorder is undertreated in the United States: nearly half receive no treatment within six months of a new diagnosis. Using a difference-in-differences specification exploiting the extension of insurance parity... View Details
      Keywords: Opioid Treatment; Medication-assisted Treatment; Substance Use Disorder; Private Insurance; Insurance; Health Care and Treatment
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      Barrette, Eric, Leemore S. Dafny, and Karen Shen. "Do Policies to Increase Access to Treatment for Opioid Use Disorder Work?" American Journal of Health Economics 9, no. 3 (Summer 2023): 297–330.
      • June 2023 (Revised July 2024)
      • Case

      Biogen and the Aduhelm Melee

      By: Amitabh Chandra and Lauren Gunasti
      Alzheimer's Disease is a devastating condition affecting millions of Americans. At this time, there is no cure. In 2021, Biogen's Aduhelm (aducanumab) received FDA approval under the accelerated approval pathway after a controversial approval process.

      This... View Details
      Keywords: Health Testing and Trials; Governing Rules, Regulations, and Reforms; Valuation; Product Development; Pharmaceutical Industry
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      Chandra, Amitabh, and Lauren Gunasti. "Biogen and the Aduhelm Melee." Harvard Business School Case 623-046, June 2023. (Revised July 2024.)
      • June 2023 (Revised June 2023)
      • Supplement

      Roche: Innovation and Access to Healthcare

      By: George Serafeim
      In May 2022, Roche Group, one of the largest healthcare companies in the world, hosted its first investor event focused exclusively on its efforts to impact access to healthcare. While Roche had recently set an ambitious goal to double the number of patients that had... View Details
      Keywords: ESG (Environmental, Social, Governance) Performance; Sustainable Finance; Growth Strategy And Execution; Sustainability Targets; Impact Evaluation; Healthcare Access; Healthcare Innovation; Healthcare Systems; Healthcare Operations; Finance; Strategy; Health Testing and Trials; Health Care and Treatment; Growth Management; Measurement and Metrics; Innovation Strategy; Corporate Social Responsibility and Impact; Health Industry; Health Industry; Switzerland; North America; Europe; Asia; Latin America; Africa
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      Serafeim, George. "Roche: Innovation and Access to Healthcare." Harvard Business School Multimedia/Video Supplement 123-713, June 2023. (Revised June 2023.)
      • June 2023 (Revised November 2023)
      • Case

      Sober Sidekick

      By: Jeffrey J. Bussgang and Kumba Sennaar
      Case on the nascent business model of a mobile health IT startup. In particular, should they pivot away from their successful lead generation business model to charging health plans. View Details
      Keywords: Entrepreneurship; Venture Capital; Operations; Business Startups; Business Model; Health Industry; United States
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      Bussgang, Jeffrey J., and Kumba Sennaar. "Sober Sidekick." Harvard Business School Case 823-066, June 2023. (Revised November 2023.)
      • 3 Jun 2023
      • Talk

      Health Care Innovation Opportunities Created by COVID-19 and How to Make Them Happen

      By: Regina E. Herzlinger
      The crush of patients created by COVID enabled the creation of sites for care outside the traditional hospital, such as retail pharmacies, ambulatory surgery centers, urgent care centers, telemedicine, and wireless sensors. Public policy mirrored these changes by... View Details
      Keywords: Policy; Health Pandemics; Health Care and Treatment; Innovation and Invention; Health Industry; Health Industry
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      Herzlinger, Regina E. "Health Care Innovation Opportunities Created by COVID-19 and How to Make Them Happen." Harvard Business School Alumni Reunion, Boston, MA, June 3, 2023. (Link to cases described in this talk.)
      • June 2023
      • Teaching Note

      From Cradle to Heaven: Taikang Insurance Group

      By: William C. Kirby and Noah B. Truwit
      Teaching Note for HBS Case No. 320-088. The case explores the rise of Taikang Insurance Group and its quest to be a leader of one of China's fastest-growing industries. Due to China's underdeveloped social welfare state, Taikang saw an opportunity for the private... View Details
      Keywords: Health Care and Treatment; Government and Politics; Health Industry; China
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      Kirby, William C., and Noah B. Truwit. "From Cradle to Heaven: Taikang Insurance Group." Harvard Business School Teaching Note 323-126, June 2023.
      • June 2023
      • Article

      Gaining Organizational Adoption: Strategically Pacing the Deployment of Digital Innovations

      By: Rebecca Karp
      Scholars have long suggested that to foster adoption for their innovative products and services, entrepreneurs should engage with customers to better understand their unmet needs. Yet, customers frequently reside in organizations, and organizational members may not be... View Details
      Keywords: Entrepreneurship And Strategy; Digital Innovation; Healthcare; Work And Organizations; Organizational Adoption; B2B; Customers; Technology Adoption; Innovation Strategy; Organizational Change and Adaptation
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      Karp, Rebecca. "Gaining Organizational Adoption: Strategically Pacing the Deployment of Digital Innovations." Academy of Management Journal 66, no. 3 (June 2023): 773–796.
      • June 2023
      • Article

      The Effect of Firms' Information Exposure on Safeguarding Employee Health: Evidence from COVID-19

      By: Lisa Yao Liu and Shirley Lu
      We show that information exposure through international business networks enables firms to take proactive measures that benefit employees and potentially the local community. Specifically, in the early days of COVID-19, firms that have business networks with China and... View Details
      Keywords: COVID-19 Pandemic; Networks; Knowledge Use and Leverage; Health Pandemics; Decision Choices and Conditions; Corporate Social Responsibility and Impact
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      Liu, Lisa Yao, and Shirley Lu. "The Effect of Firms' Information Exposure on Safeguarding Employee Health: Evidence from COVID-19." Journal of Accounting Research 61, no. 3 (June 2023): 891–933.
      • June 2023
      • Case

      Verve Therapeutics: Taking DNA Editing to Heart

      By: Shikhar Ghosh and Shweta Bagai
      Verve Therapeutics, a public biotech company based in Boston, created a novel approach to addressing cardiovascular disease (CVD) - a leading cause of deaths globally. The company's approach was a single shot treatment to permanently lower cholesterol, thus reducing... View Details
      Keywords: AI; Genetic Engineering; Medicine; Health Care and Treatment; Genetics; Innovation Strategy; Business and Stakeholder Relations; Medical Specialties; Innovation and Invention; Entrepreneurship; Biotechnology Industry
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      Ghosh, Shikhar, and Shweta Bagai. "Verve Therapeutics: Taking DNA Editing to Heart." Harvard Business School Case 823-113, June 2023.
      • May 2023 (Revised June 2023)
      • Case

      Novartis (A): Reimagining Medicine

      By: Ramon Casadesus-Masanell, Claudio Feser, Karolin Frankenberger and David Redaschi
      This case unfolds around the first-ever approved personalized cancer treatment, how Novartis wrapped it into a new business model design, and how Novartis scaled it. Novartis — one of the largest pharmaceutical companies in the world — is, among other ventures,... View Details
      Keywords: Health Care and Treatment; Business Model; Leadership; Pharmaceutical Industry; Switzerland
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      Casadesus-Masanell, Ramon, Claudio Feser, Karolin Frankenberger, and David Redaschi. "Novartis (A): Reimagining Medicine." Harvard Business School Case 723-443, May 2023. (Revised June 2023.)
      • May 2023 (Revised June 2023)
      • Supplement

      Novartis (B): Reimagining Medicine

      By: Ramon Casadesus-Masanell, Claudio Feser, Karolin Frankenberger and David Redaschi
      This case unfolds around the first-ever approved personalized cancer treatment, how Novartis wrapped it into a new business model design, and how Novartis scaled it. Novartis — one of the largest pharmaceutical companies in the world — is, among other ventures,... View Details
      Keywords: Health Care and Treatment; Business Model; Production; Business Strategy; Pharmaceutical Industry
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      Casadesus-Masanell, Ramon, Claudio Feser, Karolin Frankenberger, and David Redaschi. "Novartis (B): Reimagining Medicine." Harvard Business School Supplement 723-444, May 2023. (Revised June 2023.)
      • May 2023 (Revised June 2023)
      • Supplement

      Novartis (C): Reimagining Medicine

      By: Ramon Casadesus-Masanell, Claudio Feser, Karolin Frankenberger and David Redaschi
      This case unfolds around the first-ever approved personalized cancer treatment, how Novartis wrapped it into a new business model design, and how Novartis scaled it. Novartis — one of the largest pharmaceutical companies in the world — is, among other ventures,... View Details
      Keywords: Health Testing and Trials; Health Care and Treatment; Business Model; Problems and Challenges; Pharmaceutical Industry; Switzerland
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      Casadesus-Masanell, Ramon, Claudio Feser, Karolin Frankenberger, and David Redaschi. "Novartis (C): Reimagining Medicine." Harvard Business School Supplement 723-445, May 2023. (Revised June 2023.)
      • May 2023
      • Article

      A Public Health Approach to Negative News Media: The 3-to-1 Solution

      By: Tyler VanderWeele and Arthur C. Brooks
      There is clear evidence that the prevalence of negative media reporting has increased substantially over the past years. There is evidence also that this negative reporting adversely affects social interactions, as well as health and well-being outcomes. Given the wide... View Details
      Keywords: News; Social Networks; Contagion; Population Health; Media; Health; Welfare; Organizational Change and Adaptation; Journalism and News Industry
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      VanderWeele, Tyler, and Arthur C. Brooks. "A Public Health Approach to Negative News Media: The 3-to-1 Solution." American Journal of Health Promotion 37, no. 4 (May 2023): 447–449.
      • 2023
      • Working Paper

      Causes and Consequences of State Violence against Civilians: The Rohingya of Myanmar

      By: C. Austin Davis, Paula Lopez-Pena, A. Mushfiq Mobarak and Jaya Wen
      The Rohingya crisis is a severe, ongoing conflict involving large-scale violence and forced displacement, yet its causes are contested and its consequences lack systematic documentation. We marshal a variety of existing and original data to shed light on its drivers,... View Details
      Keywords: War; Conflict and Resolution; Motivation and Incentives; Developing Countries and Economies; Myanmar
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      Davis, C. Austin, Paula Lopez-Pena, A. Mushfiq Mobarak, and Jaya Wen. "Causes and Consequences of State Violence against Civilians: The Rohingya of Myanmar." Working Paper, August 2023.
      • 2023
      • Article

      Conduit Incentives: Eliciting Cooperation from Workers Outside of Managers' Control

      By: Susanna Gallani
      Can managers use monetary incentives to elicit cooperation from workers they cannot reward for their efforts? I study “conduit incentives,” an innovative incentive design, whereby managers influence bonus-ineligible workers’ effort by offering bonus-eligible employees... View Details
      Keywords: Organizational Behavior Modification; Peer Monitoring; Persistence Of Performance Improvements; Crowding Out; Implicit Incentives; Compensation; Healthcare; Social Pressure; Image Motivation; Incentives; Motivation; Performance; Behavior; Motivation and Incentives; Compensation and Benefits; Governing Rules, Regulations, and Reforms; Organizational Culture; Health Industry; California
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      Gallani, Susanna. "Conduit Incentives: Eliciting Cooperation from Workers Outside of Managers' Control." Accounting Review 93, no. 3 (2023): 1–28.
      • May 2023
      • Article

      Decarbonizing Health Care: Engaging Leaders in Change

      By: Vivian S. Lee, Kathy Gerwig, Emily Hough, Kedar Mate, Robert Biggio and Robert S. Kaplan
      Health care leaders are often surprised to learn that their operations contribute significantly to a warming climate. In addition to their roles as responders to and victims of extreme weather events, health care organizations have an obligation to reduce... View Details
      Keywords: Health Care; Decarbonization; Carbon Emissions; Net-zero Emissions; Climate Change; Health Care and Treatment; Health Industry
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      Lee, Vivian S., Kathy Gerwig, Emily Hough, Kedar Mate, Robert Biggio, and Robert S. Kaplan. "Decarbonizing Health Care: Engaging Leaders in Change." NEJM Catalyst Innovations in Care Delivery 4, no. 5 (May 2023).
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