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05 Jan 2011
Op-Ed

Funding Unpredictability Around Stem-Cell Research Inflicts Heavy Cost on Scientific Progress

In light of the latest developments of the on-again, off-again, on-again government funding of human embryonic stem-cell research, it is time to consider the devastating implications of this chaotic funding environment. And to do that, one needs to understand how a... View Details

Keywords: by William Sahlman; Biotechnology; Biotechnology; Biotechnology

01 Sep 2020
Cold Call Podcast

How to Launch a New Biosciences Product: Start Small or Dive in?

Keywords: Re: Jeffrey J. Bussgang; Pharmaceutical; Biotechnology

30 May 2007
Research & Ideas

Health Care Under a Research Microscope

The $2 trillion health care system is one of the United States' largest industries—but one of its worst performing by almost any measure other than technological innovation. The problems are painful, including escalating costs, expensive insurance premiums, lack of... View Details

Keywords: by Sean Silverthorne; Biotechnology; Biotechnology

May 1999
Teaching Note

Genset: 1989 TN

By: Paul A. Gompers

Teaching Note for (9-298-070). View Details

Keywords: Biotechnology Industry; France

January 2025
Case

Moderna: Democratizing Artificial Intelligence

By: Iavor I. Bojinov, Karim R. Lakhani, Annika Hildebrandt and James Weber

The case study examines Moderna's journey in democratizing artificial intelligence (AI), particularly generative AI, across its workforce. It details the company's "digital-first, AI-focused" approach, including the rollout of OpenAI's ChatGPT Enterprise to all... View Details

Keywords: AI and Machine Learning; Technology Adoption; Innovation Strategy; Governance Controls; Biotechnology Industry

March 2020 (Revised June 2020)
Case

Social Salary Setting at Spiber

By: Ashley Whillans and John Beshears

Can a “set your own salary” system boost employee happiness and motivation? Spiber made synthetic silk built from proteins mimicking the proteins found in spider silk, the world’s toughest known material by weight. Kazuhide Sekiyama and Junichi Sugahara established... View Details

Keywords: Compensation and Benefits; Motivation and Incentives; Happiness; Negotiation Tactics; Cross-Cultural and Cross-Border Issues; Biotechnology Industry; Japan; United States

September 2019 (Revised August 2020)
Case

Engineering an Inclusive Bioeconomy

By: Tarun Khanna, Raffaella Sadun and Susie L. Ma

In 2019, entrepreneur Juan Carlos Castilla-Rubio was developing a project he hoped could generate and share wealth from the natural resources of the Amazon without destroying those resources. His idea, called Earth Bank of Codes (EBC), would create a library of the... View Details

November 2017
Case

Passion and Strategy: Novozymes' Embrace of the UN Sustainable Development Goals

By: Andy Zelleke and Emilie Billaud

This case explores the sustainability efforts at Novozymes, the world's largest and oldest producer of industrial enzymes. In 2015, the Danish company became the world’s first company known to have crafted a new corporate strategy based on the United Nations... View Details

Keywords: Corporate Governance; Transformation; Environmental Sustainability; Corporate Social Responsibility and Impact; Mission and Purpose; Business and Shareholder Relations; Business and Stakeholder Relations; Business Strategy; Organizational Culture; Organizational Change and Adaptation; Biotechnology Industry; Europe; Denmark

September 2011
Teaching Note

Tengion: Bringing Regenerative Medicine to Life (TN)

By: Elie Ofek and Natalie Kindred

Teaching Note for 510031. View Details

Keywords: Partners and Partnerships; Production; Marketing; Cash; Health Care and Treatment; Medical Specialties; Research and Development; Biotechnology Industry

September 2009
Teaching Note

iZumi (TN)

By: Robert F. Higgins

Teaching Note for [809105]. View Details

Keywords: Perspective; Intellectual Property; Venture Capital; Innovation and Invention; Investment; Financing and Loans; Information Technology; Mergers and Acquisitions; Commercialization; Biotechnology Industry

December 2004 (Revised July 2005)
Case

Extend Fertility

By: Myra M. Hart and Sylvia Sensiper

Focuses on the search for opportunity, the generation and evaluation of business concepts, creation of a business plan, and the start-up process. Follows experienced entrepreneur Christy Jones as she combines her business skills and personal experience to generate new... View Details

Keywords: Opportunities; Business Plan; Entrepreneurship; Personal Development and Career; Social Issues; Gender; Business Startups; Biotechnology Industry

June 2003 (Revised October 2003)
Case

Institut Pasteur

The Pasteur Institut is implementing a proactive commercialization strategy under the direction of Christian Policard. Highlights the government's innovation policy and the role that the Pasteur Institut can play in shaping it. Also addresses issues relating to higher... View Details

Keywords: Commercialization; Research and Development; Biotechnology Industry; France

October 2001 (Revised March 2008)
Case

Anagene, Inc.

By: Robert S. Kaplan and Christina L. Darwall

An entrepreneurial, publicly traded biotech company has begun production and sales of its core product--cartridges that permit DNA samples to be analyzed on a microchip. In the early quarters, sales are difficult to forecast and the company has experienced fluctuating... View Details

Keywords: Cost Accounting; Financial Reporting; Production; Performance Capacity; Risk and Uncertainty; Genetics; Governing and Advisory Boards; Biotechnology Industry; California

February 1994
Case

Alpha-Beta Technology, Inc.: Pioneering Carbohydrate Technology

Alpha-Beta was founded in 1988 by two scientist-entrepreneurs with ten patents on carbohydrate technology. In 1991, the company faces critical questions about how to focus its product definition from among several promising, but risky, choices. How should they analyze... View Details

Keywords: Technological Innovation; Product Design; Entrepreneurship; Product Development; Biotechnology Industry

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November 1978 (Revised October 1989)
Case

Amicon Corp. (A)

Amicon holds a patent on a new process for the separation of blood plasma from whole blood. It has to decide whether to pursue a direct entry, joint venture, or licensing strategy. If it chooses licensing, there are many sub-issues to consider. View Details

Keywords: Technology; Patents; Commercialization; Health Care and Treatment; Biotechnology Industry

October 1987
Case

T Cell Sciences, Inc.

By: Francis Aguilar

Keywords: Biotechnology Industry

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October 2009 (Revised January 2014)
Teaching Note

Sustainability at Millipore (TN)

By: Michael W. Toffel

Teaching Note for [610012]. View Details

Keywords: Environmental Sustainability; Organizational Structure; Investment; Projects; Performance Improvement; Framework; Measurement and Metrics; Corporate Disclosure; Biotechnology Industry

12 Sep 2006
First Look

First Look: September 12, 2006

alliance contracts, all of which concern early-stage research at small, biotechnology R&D companies. Staged investment is ubiquitous, but solutions to agency problems vary. The cycle of equity participation in alliances resembles what... View Details

Keywords: Sean Silverthorne

08 Dec 2003
Research & Ideas

Why Europe Lags in Pharmaceuticals and Biotech

Governmental, academic, and cultural differences are hurting Europe's chances of creating more competitive pharmaceutical and biotech industries—and not much hope is on the horizon, according to a panel of experts at the 2003 HBS European Business Conference. Although... View Details

Keywords: by Sean Silverthorne; Biotechnology; Biotechnology; Biotechnology; Biotechnology

June 1990 (Revised April 1993)
Teaching Note

Novo Industri A/S--1981, Teaching Note

By: W. Carl Kester

Teaching Note for (9-286-084). View Details

Keywords: Biotechnology Industry; Biotechnology Industry; Denmark; United States

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