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  • All HBS Web  (637)
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    • News  (57)
    • Research  (448)
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  • 12 Sep 2006
  • First Look

First Look: September 12, 2006

alliance contracts, all of which concern early-stage research at small, biotechnology R&D companies. Staged investment is ubiquitous, but solutions to agency problems vary. The cycle of equity participation in alliances resembles what... View Details
Keywords: Sean Silverthorne
  • 03 Feb 2009
  • First Look

First Look: February 3, 2009

Contractibility and Contract Design in Strategic Alliances Authors: Josh Lerner and Ulrike Malmendier Publication: American Economic Review (forthcoming) Abstract We analyze how variations in contractibility affect the design of contracts in the context of View Details
Keywords: Martha Lagace
  • 05 Dec 2013
  • Op-Ed

Encourage Breakthrough Health Care by Competing on Products Rather Than Patents

Like many people interested in the tangled connections between health care progress and intellectual property rights, I avidly followed the Myriad Genetics case, decided by the Supreme Court this June 13. In sum, molecular diagnostics maker Myriad sought "the... View Details
Keywords: by Richard G. Hamermesh; Biotechnology; Biotechnology
  • 26 Jul 2024
  • Research & Ideas

Why Great Ideas Get Stuck in Universities

Entrepreneurs must overcome many barriers to get discoveries to market, but academic researchers face an additional one they might not realize: themselves. Academics tend to develop a myopic focus on the unique expertise they spend their lives developing, but that... View Details
Keywords: by Ben Rand; Biotechnology; Biotechnology
  • May 1999
  • Teaching Note

Elliot Lebowitz TN

By: Paul A. Gompers
Teaching Note for (9-297-094). View Details
Keywords: Biotechnology Industry
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Gompers, Paul A. "Elliot Lebowitz TN." Harvard Business School Teaching Note 299-060, May 1999.
  • January 1998 (Revised September 2001)
  • Case

Genset: 1989

By: Paul A. Gompers and Amy Burroughs
Discusses the start-up strategy at Genset, a French biotech firm. Pascal Brandys, a venture capitalist, and Marc Vasseur, a leading French scientist, must decide how to proceed. Future real options are central to the strategy. View Details
Keywords: Strategy; Venture Capital; Business Startups; Biotechnology Industry; France
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Gompers, Paul A., and Amy Burroughs. "Genset: 1989." Harvard Business School Case 298-070, January 1998. (Revised September 2001.)
  • June 1997 (Revised September 1997)
  • Case

Genset Initial Public Offering (B)

By: Paul A. Gompers and Jeffrey M. Anapolsky
Supplements the (A) case. View Details
Keywords: Business Model; Initial Public Offering; Genetics; Going Public; Management Teams; Biotechnology Industry; France; United States
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Gompers, Paul A., and Jeffrey M. Anapolsky. "Genset Initial Public Offering (B)." Harvard Business School Case 297-097, June 1997. (Revised September 1997.)
  • March 2018 (Revised July 2018)
  • Case

Greenlight Biosciences: In Search of Impact Investment

By: Michael Chu, Annelena Lobb and Joni Coughlin
Greenlight Biosciences, a biotech company, is in search of impact investment for its next round of financing. View Details
Keywords: Impact Investment; Investment; Environmental Sustainability; Financing and Loans; Biotechnology Industry
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Chu, Michael, Annelena Lobb, and Joni Coughlin. "GreenLight Biosciences: In Search of Impact Investment." Harvard Business School Case 318-072, March 2018. (Revised July 2018.)
  • November 2016
  • Case

Anthony Starks at InSiL Therapeutics (A)

By: Gary Pisano and Vicki Sato
When Bruce Wayne hired Anthony Starks, he thought he had hit a home run by getting the most brilliant and passionate scientist-leader in the field to be his CSO. But a few months in, Wayne and Starks begin to clash over crucial forward-looking decisions about the... View Details
Keywords: Biotech; Silicon; Managing Innovation; Management Challenges; Managing People; Managing Organization; R&D; R&D Project Management; Platform; Venture Capital; Drug Discovery; management; Biotechnology Industry; California
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Pisano, Gary, and Vicki Sato. "Anthony Starks at InSiL Therapeutics (A)." Harvard Business School Case 617-029, November 2016.
  • January 2012 (Revised August 2012)
  • Case

Dirigo International

By: Christopher M. Gordon and Chad M. Carr
Dirigo International is proposing a major expansion of their life sciences research and manufacturing facilities in the heart of a major city and middle to lower income residential neighborhood. The company and city government are seeking a development solution in the... View Details
Keywords: Production; Property; Expansion; Governing Rules, Regulations, and Reforms; Business and Government Relations; Research and Development; Outcome or Result; Biotechnology Industry
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Gordon, Christopher M., and Chad M. Carr. "Dirigo International." Harvard Business School Case 212-056, January 2012. (Revised August 2012.)
  • August 2010 (Revised August 2012)
  • Supplement

Generation Health: A Pioneer in Genetics Benefit Management (B)

By: Robert F. Higgins
Keywords: Health; Research and Development; Biotechnology Industry
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Higgins, Robert F. "Generation Health: A Pioneer in Genetics Benefit Management (B)." Harvard Business School Supplement 811-005, August 2010. (Revised August 2012.)
  • January 2010 (Revised August 2011)
  • Case

Ganeden Biotech, Inc.

By: Robert C. Pozen, Dale Alan Winger and Matthew Kenneth Ahlers
The CEO of Ganeden Biotech, a small firm with several viable probiotic products but limited resources, must decide what markets to invest in and what intellectual property strategies will best serve its immediate and longer-term business interests. View Details
Keywords: Entrepreneurship; Investment; Intellectual Property; Market Entry and Exit; Business Strategy; Biotechnology Industry
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Pozen, Robert C., Dale Alan Winger, and Matthew Kenneth Ahlers. "Ganeden Biotech, Inc." Harvard Business School Case 310-073, January 2010. (Revised August 2011.)
  • November 2009 (Revised March 2010)
  • Case

Managing Drugs on the Forefront of Personalized Medicine: The Erbitux and Vectibix Story

By: Richard G. Hamermesh, Raju Kucherlapati and Rachel Gordon
In May 2007, Amgen Inc. (Amgen) received disappointing news from the European Medicines Agency (EMEA) that its drug Vectibix, developed to fight metastatic colorectal cancer, had been rejected. This was especially surprising news given that a similar rival drug had... View Details
Keywords: Entrepreneurship; Governing Rules, Regulations, and Reforms; Health Testing and Trials; Marketing Strategy; Product Positioning; Genetics; Biotechnology Industry; Europe; United States
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Hamermesh, Richard G., Raju Kucherlapati, and Rachel Gordon. "Managing Drugs on the Forefront of Personalized Medicine: The Erbitux and Vectibix Story." Harvard Business School Case 810-066, November 2009. (Revised March 2010.)
  • July 2009
  • Teaching Note

Targanta Therapeutics: Hitting a Moving Target (TN)

By: Arthur A. Daemmrich
Teaching Note for [709002]. View Details
Keywords: Governing Rules, Regulations, and Reforms; Product Development; Business Strategy; Initial Public Offering; Mergers and Acquisitions; Policy; Selection and Staffing; Health Testing and Trials; Resource Allocation; Biotechnology Industry
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Daemmrich, Arthur A. "Targanta Therapeutics: Hitting a Moving Target (TN)." Harvard Business School Teaching Note 710-006, July 2009.
  • May 2004
  • Teaching Note

Monsanto: Technology Cooperation and Small Holder Farmer Projects (TN)

By: James E. Austin and Diana Barrett
Teaching Note to (9-302-068). View Details
Keywords: Biotechnology Industry
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Austin, James E., and Diana Barrett. "Monsanto: Technology Cooperation and Small Holder Farmer Projects (TN)." Harvard Business School Teaching Note 304-108, May 2004.
  • November 2001 (Revised December 2002)
  • Case

Tracking Stocks at Genzyme (A)

By: Malcolm S. Salter
Genzyme, a tracking stock pioneer, has used its innovative capital structure as a way to frame and grow its R&D-intensive business. Facing the question of how best to integrate a new acquisition into its tracking stock structure, Genzyme's top management is forced to... View Details
Keywords: Integration; Value Creation; Motivation and Incentives; Conflict of Interests; Stocks; Capital Structure; Research and Development; Corporate Governance; Biotechnology Industry
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Salter, Malcolm S. "Tracking Stocks at Genzyme (A)." Harvard Business School Case 902-023, November 2001. (Revised December 2002.)
  • October 2001
  • Case

TIGR and ILRI: Solving Problems with Genomics

By: Ray A. Goldberg and James M Beagle
Discusses nonprofit institutional leadership applying advances in genetic science to solve health and animal problems in industrial countries and the developing world. View Details
Keywords: Developing Countries and Economies; Health; Technological Innovation; Leading Change; Emerging Markets; Genetics; Non-Governmental Organizations; Technology Adoption; Biotechnology Industry
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Goldberg, Ray A., and James M Beagle. "TIGR and ILRI: Solving Problems with Genomics." Harvard Business School Case 902-409, October 2001.
  • October 2001 (Revised June 2002)
  • Case

Centagenetix (A): Building a Business Model for Genetic Longevity

Describes a start-up company seeking to exploit population genetic data from long-lived, healthy people. The company must address legal, financial, ethical, and personal issues among its team to launch the company. View Details
Keywords: Ethics; Genetics; Business Startups; Biotechnology Industry
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Chesbrough, Henry W., and Frank Angella. "Centagenetix (A): Building a Business Model for Genetic Longevity." Harvard Business School Case 602-087, October 2001. (Revised June 2002.)
  • April 2001 (Revised January 2003)
  • Case

Robert Shapiro and Monsanto

Traces Monsanto's efforts to become a global biotech powerhouse under Shapiro's leadership. Examines how his crusade to save the world through genetic modification foundered. View Details
Keywords: Genetics; Supply Chain Management; Alliances; Global Strategy; Cross-Cultural and Cross-Border Issues; Biotechnology Industry
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Watkins, Michael D., and Ann Leamon. "Robert Shapiro and Monsanto." Harvard Business School Case 801-426, April 2001. (Revised January 2003.)
  • December 2000
  • Case

Paradigm Genetics: The Industrialization of Genomics

By: Ray A. Goldberg, Carin-Isabel Knoop and Laure Mougeot Stroock
Keywords: Genetics; Biotechnology Industry
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Goldberg, Ray A., Carin-Isabel Knoop, and Laure Mougeot Stroock. "Paradigm Genetics: The Industrialization of Genomics." Harvard Business School Case 901-011, December 2000.
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