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- 2024
- Working Paper
Prozac—Controversial Blockbuster: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes the development of Prozac, a blockbuster drug that transformed
the treatment of depression – and became a cultural phenomenon in the United States. Specifically, we
chronicle the: 1) prior treatments for depression and the research that... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Prozac—Controversial Blockbuster: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-135, July 2020. (Revised May 2024.)
- 2024
- Working Paper
Tamoxifen—Reducing Breast Cancer Risks: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant Datar and Katherine Stebbins
We describe the development of tamoxifen, considered a “gold standard” treatment for
millions of breast cancer patients. Specifically, we describe breast cancer treatments before tamoxifen’s
development; the initial development of tamoxifen from 1960 to 1973;... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation and Invention; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Governing Rules, Regulations, and Reforms
Bhidé, Amar, Srikant Datar, and Katherine Stebbins. "Tamoxifen—Reducing Breast Cancer Risks: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-134, July 2020. (Revised May 2024.)
- June 2020 (Revised January 2024)
- Case
TraceTogether
By: Mitchell B. Weiss and Sarah Mehta
By April 7, 2020, over 1.4 million people worldwide had contracted the novel coronavirus (COVID-19). Governments raced to curb the spread of COVID-19 by scaling up testing, quarantining those infected, and tracing their possible contacts. It had taken Singapore’s... View Details
Keywords: COVID-19; Contact Tracing; Government Administration; Crisis Management; Health; Health Pandemics; Innovation and Invention; Innovation Leadership; Innovation Strategy; Technological Innovation; Social Issues; Information Technology; Mobile and Wireless Technology; Applications and Software; Technology Adoption; Health Industry; Public Administration Industry; Singapore
Weiss, Mitchell B., and Sarah Mehta. "TraceTogether." Harvard Business School Case 820-111, June 2020. (Revised January 2024.)
- June 2020
- Article
Frenemies in Platform Markets: Heterogeneous Profit Foci as Drivers of Compatibility Decisions
By: Ron Adner, Jianqing Chen and Feng Zhu
We study compatibility decisions of two competing platform owners that generate profits through both hardware sales and royalties from content sales. We consider a game-theoretic model in which two platforms offer different standalone utilities to users. We find that... View Details
Keywords: Compatibility; Platform Competition; Profit Foci; Digital Platforms; Competition; Profit; Decision Making
Adner, Ron, Jianqing Chen, and Feng Zhu. "Frenemies in Platform Markets: Heterogeneous Profit Foci as Drivers of Compatibility Decisions." Management Science 66, no. 6 (June 2020): 2432–2451.
- April 2020 (Revised February 2023)
- Case
GitLab and the Future of All-Remote Work (A)
By: Prithwiraj Choudhury and Emma Salomon
GitLab is arguably one of the world’s largest “all-remote” companies. Started in 2011 and with more than 1,000 employees at present, it has no physical offices and all employees, including the entire C-Suite, work remotely from all parts of the world. The case... View Details
Keywords: Remote Work; Internet and the Web; Technology Adoption; Value Creation; Business Model; Organizational Structure
Choudhury, Prithwiraj, and Emma Salomon. "GitLab and the Future of All-Remote Work (A)." Harvard Business School Case 620-066, April 2020. (Revised February 2023.)
- Spring 2020
- Article
The Basic Economics of Internet Infrastructure
By: Shane Greenstein
The internet's structure and operations remain invisible to most economists. What determines the economic value of internet infrastructure and the incentives to improve it? What are the open research questions for the most salient policy issues? This article reviews... View Details
Greenstein, Shane. "The Basic Economics of Internet Infrastructure." Journal of Economic Perspectives 34, no. 2 (Spring 2020): 192–214.
- March 2020
- Case
Voi Technology
By: Jeffrey F. Rayport and Olivia Hull
Voi Technology, a fast-growing start-up out of Sweden, is competing in the highly contested European e-scooter sharing market. With a presence in nearly 40 cities in Europe by February 2020, the firm is working hard to improve its unit economics to reach profitability.... View Details
Keywords: Entrepreneurship; Business Strategy; Technology Adoption; Innovation Strategy; Technological Innovation; Marketing Strategy; Business Plan; Product Marketing; Product Launch; Product Positioning; Energy Conservation; Cross-Cultural and Cross-Border Issues; Global Strategy; Globalized Economies and Regions; Innovation Leadership; Human Capital; Laws and Statutes; Growth Management; Operations; Logistics; Service Operations; Supply Chain Management; Organizational Culture; Information Infrastructure; Transportation; Technology Industry; Technology Industry; Europe
Rayport, Jeffrey F., and Olivia Hull. "Voi Technology." Harvard Business School Case 820-099, March 2020.
- February 2020
- Case
Klöckner & Co: Steeling for a Digital World
By: Scott Duke Kominers and Carin-Isabel Knoop
Hoping to get ahead of potential digital disruption at Klöckner & Co.—one of the world’s largest steel and metal distributors—CEO Gisbert Rühl set up both kloeckner.i (KCI), an internal transformation arm, and XOM Materials (XOM), an independent industry platform. KCI... View Details
Keywords: Corporate Entrepreneurship; Market Design; Digital Platforms; Markets; Industry Structures; Supply and Industry; Technology Adoption; Transformation; Digital Transformation; Information Technology Industry; Information Technology Industry; Europe; Germany
Kominers, Scott Duke, and Carin-Isabel Knoop. "Klöckner & Co: Steeling for a Digital World." Harvard Business School Case 820-035, February 2020.
- February 2020
- Technical Note
Talent Management and the Future of Work
By: William R. Kerr and Gorick Ng
The nature of work is changing—and it is changing rapidly. Few days go by without industry giants such as Amazon and AT&T announcing plans to invest billions of dollars towards retraining nearly half of their respective workforces for jobs of the future. What changes... View Details
Keywords: Human Resource Management; Human Capital Development; Human Resource Practices; Talent; Talent Acquisition; Talent Development; Talent Development And Retention; Talent Management; Talent Retention; Labor Flows; Labor Management; Labor Market; Strategy Development; Strategy Management; Strategy Execution; Strategy And Execution; Strategic Change; Transformations; Organization; Organization Alignment; Organization Design; Organizational Adaptation; Organizational Effectiveness; Management Challenges; Management Of Business And Political Risk; Change Leadership; Future Of Work; Future; Skills Gap; Skills Development; Skills; Offshoring And Outsourcing; Investment; Capital Allocation; Work; Work Culture; Work Force Management; Work/life Balance; Work/family Balance; Work-family Boundary Management; Workers; Worker Productivity; Worker Performance; Work Engagement; Work Environment; Work Environments; Productivity; Organization Culture; Soft Skills; Technology Management; Technological Change; Technological Change: Choices And Consequences; Technology Diffusion; Disruptive Technology; Global Business; Global; Workplace; Workplace Context; Workplace Culture; Workplace Wellness; Collaboration; Competencies; Productivity Gains; Digital; Digital Transition; Competitive Dynamics; Competitiveness; Competitive Strategy; Data Analytics; Data; Data Management; Data Strategy; Data Protection; Aging Society; Diversity; Diversity Management; Millennials; Communication Complexity; Communication Technologies; International Business; Work Sharing; Global Competitiveness; Global Corporate Cultures; Intellectual Property; Intellectual Property Management; Intellectual Property Protection; Intellectual Capital And Property Issues; Globalization Of Supply Chain; Inequality; Recruiting; Hiring; Hiring Of Employees; Training; Job Cuts And Outsourcing; Job Performance; Job Search; Job Design; Job Satisfaction; Jobs; Employee Engagement; Employee Attitude; Employee Benefits; Employee Compensation; Employee Fairness; Employee Relationship Management; Employee Retention; Employee Selection; Employee Motivation; Employee Feedback; Employee Coordination; Employee Performance Management; Employee Socialization; Process Improvement; Application Performance Management; Stigma; Institutional Change; Candidates; Digital Enterprise; Cultural Adaptation; Cultural Change; Cultural Diversity; Cultural Context; Cultural Strategies; Cultural Psychology; Cultural Reform; Performance; Performance Effectiveness; Performance Management; Performance Evaluation; Performance Appraisal; Performance Feedback; Performance Measurement; Performance Metrics; Performance Measures; Performance Efficiency; Efficiency; Performance Analysis; Performance Appraisals; Performance Improvement; Automation; Artificial Intelligence; Technology Companies; Managerial Processes; Skilled Migration; Assessment; Human Resources; Management; Human Capital; Talent and Talent Management; Retention; Demographics; Labor; Strategy; Change; Change Management; Transformation; Organizational Change and Adaptation; Organizational Culture; Working Conditions; Information Technology; Technology Adoption; Disruption; Economy; Competition; Globalization; AI and Machine Learning; Digital Transformation
Kerr, William R., and Gorick Ng. "Talent Management and the Future of Work." Harvard Business School Technical Note 820-084, February 2020.
- February 2020 (Revised March 2020)
- Case
Prime Coalition: Catalytic Capital for Climate Innovation
By: Ramana Nanda, Benjamin N. Roth and Olivia Hull
With long development timelines and high risk, new energy technologies were often left to languish in the “valley of death,” unable to raise enough funds to bring a product to market. In 2014, Sarah Kearney founded the nonprofit Prime Coalition to solve this problem.... View Details
Keywords: Energy Conservation; Renewable Energy; Social Entrepreneurship; Venture Capital; Investment; Innovation and Invention; Technological Innovation; Mission and Purpose; Science-Based Business; Nonprofit Organizations; Social Enterprise; Technology Industry; Technology Industry; Technology Industry; United States
Nanda, Ramana, Benjamin N. Roth, and Olivia Hull. "Prime Coalition: Catalytic Capital for Climate Innovation." Harvard Business School Case 820-007, February 2020. (Revised March 2020.)
- January 2020
- Case
Banorte Móvil: Data-Driven Mobile Growth
By: Ayelet Israeli, Carla Larangeira and Mariana Cal
In mid-2019, Carlos Hank was deliberating over the results for Banorte Móvil—the mobile application for Banorte, Mexico’s most profitable and second-largest financial institution. Hank, who had been appointed as Banorte´s Chairman of the Board in January 2015, had... View Details
Keywords: Data Analytics; Customer Lifetime Value; Financial Institutions; Mobile and Wireless Technology; Growth and Development Strategy; Customers; Technology Adoption; Communication Strategy; Banking Industry; Mexico; Latin America
Israeli, Ayelet, Carla Larangeira, and Mariana Cal. "Banorte Móvil: Data-Driven Mobile Growth." Harvard Business School Case 520-068, January 2020.
- January 2020 (Revised January 2025)
- Case
Freelancer, Ltd.
By: Christopher Stanton, Karim R. Lakhani, Jennifer L. Hoffman, Jin Hyun Paik and Nina Cohodes
Over the course of the 2010s, the rapid advancement of mobile technologies and the rise of online freelancing platforms seemed to portend a radical transformation of labor markets into on-demand, flexible talent pools. Even though several Fortune 500... View Details
Keywords: Freelancers; Platforms; Digital Labor; Labor; Human Resources; Management; Internet and the Web; Growth and Development Strategy; Digital Platforms; Information Industry; Australia; United States; Philippines
Stanton, Christopher, Karim R. Lakhani, Jennifer L. Hoffman, Jin Hyun Paik, and Nina Cohodes. "Freelancer, Ltd." Harvard Business School Case 820-075, January 2020. (Revised January 2025.)
- January 2020
- Article
Jack of All Trades and Master of Knowledge: The Role of Diversification in New Distant Knowledge Integration
By: Frank Nagle and Florenta Teodoridis
We consider the role of individual-level diversification as a mechanism through which skilled researchers engage in successful exploration—recognizing and integrating new knowledge external to one’s domains of expertise. To approach an ideal experiment, we (1) employ a... View Details
Keywords: Individual-level Knowledge Diversification; Novel Knowledge; Knowledge Acquisition; Diversification; Innovation and Invention; Research
Nagle, Frank, and Florenta Teodoridis. "Jack of All Trades and Master of Knowledge: The Role of Diversification in New Distant Knowledge Integration." Strategic Management Journal 41, no. 1 (January 2020): 55–85.
- 2019
- Article
Overcoming Cultural Resistance to Open Source Innovation
By: John Winsor, Jin Hyun Paik, Michael Tushman and Karim R. Lakhani
Purpose: This article offers insight on how to effectively help incumbent organizations prepare for global business shifts to open source and digital business models.
Design/methodology/approach: Discussion related to observation, experience and case studies... View Details
Design/methodology/approach: Discussion related to observation, experience and case studies... View Details
Keywords: Open Source Innovation; Organizational Culture; Organizational Change and Adaptation; Business Model; Technological Innovation; Collaborative Innovation and Invention
Winsor, John, Jin Hyun Paik, Michael Tushman, and Karim R. Lakhani. "Overcoming Cultural Resistance to Open Source Innovation." Strategy & Leadership 47, no. 6 (2019): 28–33.
- November 2019 (Revised May 2020)
- Case
Collibra
By: Lynda M. Applegate, Jeffrey F. Rayport and Julia Kelley
Founded in 2008 at Vrije Universiteit Brussels, Collibra was a data intelligence company that found product-market fit in the years after the global financial crisis when many companies were under pressure from consumers and governments to improve their data management... View Details
Keywords: Entrepreneurship; Governance; Innovation and Invention; Technological Innovation; Markets; Information Technology; Applications and Software; Technology Adoption; Digital Platforms; Internet and the Web; Customer Focus and Relationships; Customer Satisfaction; Expansion; Information Technology Industry; Information Technology Industry; Europe; Belgium; Brussels; North and Central America; United States; New York (city, NY); New York (state, US)
Applegate, Lynda M., Jeffrey F. Rayport, and Julia Kelley. "Collibra." Harvard Business School Case 820-013, November 2019. (Revised May 2020.)
- November 2019
- Case
DeepMap: Charting the Road Ahead for Autonomous Vehicles
By: Shane Greenstein and Nicole Tempest Keller
Founded in 2016, DeepMap developed high definition (HD) mapping software and localization services for Level 4+ autonomous vehicles. Traditional navigational maps were accurate to a few meters, which was sufficient for drivers but not for machine-driven vehicles that... View Details
Keywords: Mapping Software; Autonomous Vehicles; Business Startups; Applications and Software; Technological Innovation; Technology Adoption; Service Delivery; Global Range; Resource Allocation; Strategic Planning; Technology Industry; Technology Industry
Greenstein, Shane, and Nicole Tempest Keller. "DeepMap: Charting the Road Ahead for Autonomous Vehicles." Harvard Business School Case 620-047, November 2019.
- September 2019 (Revised February 2020)
- Teaching Note
Fishbowl: Scaling Up
By: Leslie K. John
Email mking@hbs.edu for a courtesy copy.
Teaching Note for HBS No. 919-013. Fishbowl is a social media app that allows professionals to connect with other relevant professionals both within their company and... View Details
Teaching Note for HBS No. 919-013. Fishbowl is a social media app that allows professionals to connect with other relevant professionals both within their company and... View Details
Keywords: Communication Technologies; Customer Value; Value Chain; Interpersonal Communication; Talent and Talent Management; Customer Value and Value Chain; Entrepreneurship; Business Model; Growth and Development Strategy; Marketing Strategy; Advertising; Product Marketing; Digital Platforms; Consumer Behavior; Network Effects; Emotions; Motivation and Incentives; Trust; Applications and Software; Technology Adoption; Digital Platforms; Technology Industry; Technology Industry; Technology Industry; Technology Industry; Technology Industry; United States
John, Leslie K. "Fishbowl: Scaling Up." Harvard Business School Teaching Note 920-022, September 2019. (Revised February 2020.) (Email mking@hbs.edu for a courtesy copy.)
- 2020
- Working Paper
Digital Experimentation and Startup Performance: Evidence from A/B Testing
By: Rembrand Koning, Sharique Hasan and Aaron Chatterji
Recent work argues that experimentation is the appropriate framework for entrepreneurial strategy. We investigate this proposition by exploiting the time-varying adoption of A/B testing technology, which has drastically reduced the cost of experimentally testing... View Details
Keywords: Experimentation; A/B Testing; Data-driven Decision-making; Entrepreneurship; Strategy; Business Startups; Information Technology; Performance
Koning, Rembrand, Sharique Hasan, and Aaron Chatterji. "Digital Experimentation and Startup Performance: Evidence from A/B Testing." Harvard Business School Working Paper, No. 20-018, August 2019. (Revised September 2020. SSRN Working Paper Series, No. 3440291, August 2019)
- August 2019 (Revised March 2023)
- Case
Rand Fishkin at Moz (A)
In 2016, senior management at Moz, a venture capital–backed startup providing software tools for digital marketing professionals, must decide how to address a looming cash flow crisis precipitated by failed efforts to broaden its product line. Seattle-based Moz had... View Details
Keywords: Startups; Scaling; Entrepreneurship; Failure; Business Startups; Diversification; Growth Management; Technology Industry
Eisenmann, Thomas R. "Rand Fishkin at Moz (A)." Harvard Business School Case 820-002, August 2019. (Revised March 2023.)
- 2024
- Working Paper
Coronary Artery Bypass Grafting—Impossible to Routine: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant M. Datar and Fabio Villa
We describe how Coronary Artery Bypass Grafting (CABG, or more popularly, “bypass”) operations
revolutionized the treatment of coronary disease (that can produce fatal heart attacks and debilitating
angina). Specifically, we chronicle the: 1) development of the... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
Bhidé, Amar, Srikant M. Datar, and Fabio Villa. "Coronary Artery Bypass Grafting—Impossible to Routine: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-010, July 2019. (Revised May 2024.)