Publications

2009
Article

Synthesis by Microbes or Chemists? Pharmaceutical Research and Manufacturing in the Antibiotic Era

By: Arthur A. Daemmrich

This article presents a case study of the rise of Pfizer as a leading pharmaceutical company, with a focus on changing relationships between manufacturing technology and R&D between the mid-1940s and the mid-1960s. Pfizer first moved into pharmaceuticals through... View Details

Keywords: Research and Development; Production; Technology; Transformation; Relationships; Success; Organizations; Programs; Chemicals; Alignment; Pharmaceutical Industry; United States

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Jan W. Rivkin is a Professor in the Strategy Unit at Harvard Business School. In the past, he has served as Faculty Chair of the MBA Program, Senior Associate Dean for Research, and head of the Strategy Unit. His research, course development, and teaching focus on... View Details

Keywords: airline; computer; internet; music; transportation

Nitin Nohria

Nitin Nohria served as the tenth dean of Harvard Business School from 2010-2020. He previously served as co-chair of the Leadership Initiative, Senior Associate Dean of Faculty Development, and Head of the Organizational Behavior unit.

As Dean, building on... View Details

05 Jul 2006
Research & Ideas

The Accidental Innovator

Companies spend many hundreds of billions of dollars on R&D each year, but the microwave oven was conceived from a melted candy bar, saccharin from an accidental chemical spill, and the Daguerre photo process via a shattered... View Details

Keywords: by Sarah Jane Gilbert

September 2023 (Revised April 2024)
Case

Atomwise: Strategic Opportunities in AI for Pharma

By: Satish Tadikonda

Abraham Heifets and his co-founder, Izhar Wallach, had founded Atomwise to develop i) an AI engine to transform drug discovery by creating better medicines faster, and ii) a machine learning-based discovery engine that combined the power of convolutional neural... View Details

Keywords: Business Model; Business Startups; AI and Machine Learning; Science-Based Business; Technological Innovation; Biotechnology Industry; Biotechnology Industry

December 1997
Case

American Cyanamid (A) & (B) (Combined)

American Home Products' (AHP) $9 billion hostile takeover of American Cyanamid (Cyanamid) was the largest merger-and-acquistion transaction in 1994, and made AHP the fourth largest pharmaceutical firm in the United States. At the time of AHP's offer, Cyanamid had... View Details

Keywords: Governing and Advisory Boards; Mergers and Acquisitions; Corporate Governance; Conflict and Resolution; Pharmaceutical Industry

January 1997 (Revised July 1998)
Case

Dendrite International (Condensed)

By: John A. Deighton

This version has been shortened to concentrate on the issue of managing a long selling process and long post-sale account relationship. The focus on the pharmaceutical industry in the United States, Europe, and Japan is preserved. Broader questions of expansion into... View Details

Keywords: Customer Focus and Relationships; Marketing Strategy; Product Development; Sales; Expansion; Chemical Industry; Chemical Industry; Japan; Europe; United States

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March 2007 (Revised April 2007)
Case

Fujifilm: A Second Foundation

Fujifilm was the second largest manufacturer of photographic film in the world when digital imaging began to substitute for its core business. In contrast to some photography incumbents, such as Polaroid, Fuji had a relatively successful transition to digital imaging.... View Details

Keywords: Growth and Development Strategy; Transition; Mission and Purpose; Globalized Markets and Industries; Opportunities; Electronics Industry; Electronics Industry

September 2013
Case

SafeBlend Fracturing

By: Benson P. Shapiro, Frank V. Cespedes and Alisa Zalosh

The CEO of SafeBlend Technologies must set a price for the company's environmentally friendly fracturing fluid additive. The firm is negotiating a new contract with its biggest client, Bristol Natural Gas. For the last two years, SafeBlend has been the sole provider of... View Details

Keywords: Information Technology; Customer Relationship Management; Price; Negotiation; Competitive Advantage; Environmental Sustainability; Energy Sources; Sales; Energy Industry

John Deighton is The Harold M. Brierley Professor of Business Administration Emeritus at Harvard Business School. He is an authority on consumer behavior and marketing, with a focus on digital and direct marketing. He teaches in the area of Big Data in Marketing,... View Details

Keywords: e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry

2017
Working Paper

Creating the Market for Organic Wine: Sulfites, Certification, and Green Values

By: Geoffrey Jones and Emily Grandjean

This working paper examines the history of organic wine, which provides a case study of failed category creation. The modern organic wine industry emerged during the 1970s in the United States and Western Europe, but it struggled to gain traction compared to other... View Details

Keywords: Product Launch; Failure; Problems and Challenges; Complexity; Governing Rules, Regulations, and Reforms; Agriculture and Agribusiness Industry; Food and Beverage Industry

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14 Jan 2008
Research & Ideas

Mapping Polluters, Encouraging Protectors

Citizens, industrial polluters, and scholars do not usually see eye to eye—but that may change with a new Web site that monitors corporate environmental performance in the United States. According to the university professors who created... View Details

Keywords: by Martha Lagace; Chemical; Chemical

October 1996 (Revised December 1997)
Case

American Cyanamid (A): Boardroom Response to a Hostile Takeover Offer

American Home Products' (AHP) $9 billion hostile takeover of American Cyanamid (Cyanamid) was the largest mergers and-acquistions transaction in 1994, and made AHP the fourth largest pharmaceutical firm in the United States. At the time of AHP's offer, Cyanamid had... View Details

Keywords: Governing and Advisory Boards; Mergers and Acquisitions; Corporate Governance; Pharmaceutical Industry; United States

07 Jan 2010
Working Paper Summaries

International Differences in the Size and Roles of Corporate Headquarters: An Empirical Examination

Keywords: by David Collis, David Young & Michael Goold

Web

Curriculum - MBA

and their interactions with proteins. The physical and chemical properties that drive the interactions of proteins with nucleic acids underpins course discussions of DNA replication, DNA repair, gene regulation, transcription, and... View Details

November 1983 (Revised May 1984)
Background Note

Note on the Export of Pesticides from the United States to Developing Countries

This is an issues-oriented note designed to stimulate discussion of the ethical aspects of the sale of pesticides which are not approved for any use or only for restricted use in the United States to less developed countries. It is organized as follows: the problem,... View Details

Keywords: Pollutants; Ethics; Health; Chemicals; Developing Countries and Economies; Chemical Industry; United States