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- All HBS Web
(10,814)
- Faculty Publications (1,206)
- September 15, 2021
- Article
Improving Deconvolution Methods in Biology Through Open Innovation Competitions: An Application to the Connectivity Map
By: Andrea Blasco, Ted Natoli, Michael G. Endres, Rinat A. Sergeev, Steven Randazzo, Jin Hyun Paik, N.J. Maximilian Macaluso, Rajiv Narayan, Xiaodong Lu, David Peck, Karim R. Lakhani and Aravind Subramanian
A recurring problem in biomedical research is how to isolate signals of distinct populations (cell types, tissues, and genes) from composite measures obtained by a single analyte or sensor. Existing computational deconvolution approaches work well in many specific... View Details
Keywords: Deconvolution; Methods; Open Innovation Competition; Genomics; Research; Innovation and Invention
Blasco, Andrea, Ted Natoli, Michael G. Endres, Rinat A. Sergeev, Steven Randazzo, Jin Hyun Paik, N.J. Maximilian Macaluso, Rajiv Narayan, Xiaodong Lu, David Peck, Karim R. Lakhani, and Aravind Subramanian. "Improving Deconvolution Methods in Biology Through Open Innovation Competitions: An Application to the Connectivity Map." Bioinformatics 37, no. 18 (September 15, 2021).
- September 13, 2021
- Article
Managing Through Crunch Time—Without Burning Out Your Team
By: Flavio Serapiao, Andrew Hill and Boris Groysberg
Crunch times—the long, stressful hours of work that are often required in the final weeks before a new product launch—can have an inordinate impact on the success of businesses and they’re powerful shapers of organizational culture. Effective leaders understand that... View Details
Serapiao, Flavio, Andrew Hill, and Boris Groysberg. "Managing Through Crunch Time—Without Burning Out Your Team." Harvard Business Review Digital Articles (September 13, 2021).
- September 2021 (Revised March 2024)
- Case
Bühler: Mobilizing Industry around a Common Purpose
By: Ranjay Gulati, Franz Wohlgezogen and Malini Sen
Bühler Group, a Swiss multinational processing technology provider, started by selling machines for processing grains and later transitioned into selling food processing solutions. A family-owned business in the fifth generation, Bühler’s high-end milling, grinding,... View Details
Keywords: Family Business; Customer Focus and Relationships; Machinery and Machining; Corporate Social Responsibility and Impact; Mission and Purpose; Innovation Leadership; Switzerland
Gulati, Ranjay, Franz Wohlgezogen, and Malini Sen. "Bühler: Mobilizing Industry around a Common Purpose." Harvard Business School Case 822-001, September 2021. (Revised March 2024.)
- 2021
- Article
An Empirical Examination of Sell-Side Brokerage Analysts' Published Research, Concierge Services, and High-Touch Services
By: David A. Maber, Boris Groysberg and Paul M. Healy
This paper uses a proprietary panel dataset to categorize and quantify the activities that sell-side brokerage analysts use to build and sustain their network of buy-side client relations. We then examine the marginal impact of these activities on key analyst outcome... View Details
Maber, David A., Boris Groysberg, and Paul M. Healy. "An Empirical Examination of Sell-Side Brokerage Analysts' Published Research, Concierge Services, and High-Touch Services." European Accounting Review 30, no. 4 (2021): 827–853.
- 2021
- Working Paper
Expanding the Entrepreneurial Cultural Toolkit: The Temporal Interplay of the Substantive and the Symbolic
By: Rebecca Karp and Siobhan O'Mahony
Much research shows how entrepreneurs leverage symbolic toolkits via storytelling and narratives to convince resource providers of their venture’s legitimacy. Although investors’ legitimacy concerns may be initially met with symbolic actions, it is unclear whether... View Details
- 2021
- Article
How Top Managers Use the Entrepreneurial Gap to Drive Strategic Change
By: Robert L. Simons and Antonio Davila
Prior research provides strong evidence for the association between business strategy and the design and use of management control systems. We complement this research by examining the role of management control systems in situations of strategic change. We report the... View Details
Keywords: Management Control Systems; Accountability; Strategic Change; Organization Change And Adaptation; Organizational Performance; Management Systems; Organizational Structure; Corporate Accountability; Organizational Change and Adaptation; Performance
Simons, Robert L., and Antonio Davila. "How Top Managers Use the Entrepreneurial Gap to Drive Strategic Change." European Accounting Review 30, no. 4 (2021): 583–609.
- 2021
- Book
Lead and Disrupt: How to Solve the Innovator's Dilemma
By: Charles A. O'Reilly III and Michael Tushman
Why do successful firms find it so difficult to adapt in the face of change—to innovate? In the past ten years, the importance of this question has increased as more industries and firms confront disruptive change. The pandemic has accelerated this crisis, collapsing... View Details
Keywords: Organization Change And Adaptation; Organizational Change and Adaptation; Disruptive Innovation; Innovation and Management; Leading Change
O'Reilly, Charles A., III, and Michael Tushman. Lead and Disrupt: How to Solve the Innovator's Dilemma. Second ed. Stanford, CA: Stanford Business Books, 2021.
- 15 Jul 2021
- Interview
The Secret to Building a Higher-Performing Company—Amy Edmondson
By: Amy C. Edmondson and Jason Marc Campbell
Research shows that organizations with higher levels of psychological safety perform better on almost any metric or KPI than organizations with a low psychological safety score. Psychological safety is "a belief that one will not be punished or humiliated for speaking... View Details
"The Secret to Building a Higher-Performing Company—Amy Edmondson." Selling with Love (podcast), July 15, 2021. (Formerly Superhumans at Work.)
- 9 Jul 2021
- Interview
Matthew Barzun and Amy Edmondson
By: Amy C. Edmondson and Matthew Barzun
Writer Matthew Barzun speaks with Harvard Professor and author Amy Edmondson about Barzun's book, "The Power of Giving Away Power: How the Best Leaders Learn to Let Go". Matthew Barzun has served as U.S. ambassador to the United Kingdom and Sweden. He served as... View Details
"Matthew Barzun and Amy Edmondson." Great Podversations (podcast), July 9, 2021.
- 2021
- Book
The Power of Trust: How Companies Build It, Lose It, Regain It
By: Sandra J. Sucher and Shalene Gupta
Trust is the most powerful force underlying the success of every business. Yet it can be shattered in an instant, with a devastating impact on a company’s market cap and reputation. How to build and sustain trust requires fresh insight into why customers, employees,... View Details
Keywords: Power; Corporate Culture; Future Of Work; Innovation; Technology Strategy; Automation; Stakeholder Engagement; Employee Attitude; Customer Behavior; Shareholder Value; Government And Business; Impact Investing; Corporate Change And Sustainability; Trust; Power and Influence; Globalization; Leadership; Organizational Culture; Innovation and Invention; Human Resources; Information Technology; Strategy; Corporate Accountability; Asia; Europe; South America; Middle East; North and Central America
Sucher, Sandra J., and Shalene Gupta. The Power of Trust: How Companies Build It, Lose It, Regain It. New York: PublicAffairs, 2021.
- Summer 2021
- Article
The Cost and Evolution of Quality at Cipla Ltd, 1935–2016
By: Muhammad H. Zaman and Tarun Khanna
This article examines the evolution of Indian pharmaceutical manufacturer Cipla towards producing drugs that met the quality standards of European and U.S. regulators. It employs new research in Cipla’s corporate archives, the Creating Emerging Markets database, and... View Details
Keywords: Cipla; Pharmaceuticals; Drug Quality; Generics; Quality; Standards; Information Technology; Cost; Organizational Culture; Business History; Pharmaceutical Industry; India
Zaman, Muhammad H., and Tarun Khanna. "The Cost and Evolution of Quality at Cipla Ltd, 1935–2016." Business History Review 95, no. 2 (Summer 2021): 249–274.
- Summer 2021
- Article
The World Management Survey at 18: lessons and the way forward
By: Daniela Scur, Raffaella Sadun, John Van Reenen, Renata Lemos and Nicholas Bloom
Understanding how differences in management ‘best practices’ affect organizational outcomes has been a focus of both theoretical and empirical work in the fields of management, sociology, economics, and public policy. The World Management Survey (WMS) project was born... View Details
Keywords: Firm Objectives, Organization, And Behavior; Business Economics; Choice Of Technology; Management Of Technological Innovation And R&D; Technological Change: Choices And Consequences; Management Practices and Processes
Scur, Daniela, Raffaella Sadun, John Van Reenen, Renata Lemos, and Nicholas Bloom. "The World Management Survey at 18: lessons and the way forward." Oxford Review of Economic Policy 37, no. 2 (Summer 2021): 231–258.
- 2021
- Working Paper
Studying the U.S.-Based Portfolio Companies of U.S. Impact Investors
By: M. Diane Burton, Gurveen Chadha, Shawn A. Cole, Abhishek Dev, Christina Jarymowycz, Leslie Jeng, Laura Kelley, Josh Lerner, Jaime R. Diaz Palacios, Yue (Cynthia) Xu and T. Robert Zochowski
Recent years have seen a dramatic increase in the reliance on market-based solutions to social and environmental problems around the world (Barman 2016; Horvath and Powell 2020). The growth of impact investing is a vivid example of this trend and, although there have... View Details
Keywords: Impact Investing; Impact Portfolio Companies; Investment; Social Issues; Environmental Sustainability; Investment Portfolio; Business Ventures; Analytics and Data Science; Performance; United States
Burton, M. Diane, Gurveen Chadha, Shawn A. Cole, Abhishek Dev, Christina Jarymowycz, Leslie Jeng, Laura Kelley, Josh Lerner, Jaime R. Diaz Palacios, Yue (Cynthia) Xu, and T. Robert Zochowski. "Studying the U.S.-Based Portfolio Companies of U.S. Impact Investors." Harvard Business School Working Paper, No. 21-130, June 2021.
- May 2021
- Case
Inclusive Innovation at Mass General Brigham
By: Katherine Baldiga Coffman and Olivia Hull
Massachusetts General Brigham (MGB) Chief Innovation Officer Christopher Coburn had overseen a period of exciting transformation and growth in healthcare innovation at MGB. In November 2019, the health system was the largest recipient of National Institutes of Health... View Details
Keywords: Inclusion; Innovation; Invention; Gender; Business Startups; Investment Funds; Private Equity; Health Care and Treatment; Innovation Strategy; Technological Innovation; Intellectual Property; Copyright; Patents; Research; Research and Development; Diversification; Technology; Health Industry; Massachusetts; Boston
Coffman, Katherine Baldiga, and Olivia Hull. "Inclusive Innovation at Mass General Brigham." Harvard Business School Case 921-006, May 2021.
- May 2021
- Case
The SMA Foundation: Steering Therapeutic Research and Development in a Rare Disease
By: Amitabh Chandra, Spencer Lee-Rey and Caroline Marra
This case explores incentives for rare disease drug development by chronicling the role of the Spinal Muscular Atrophy (SMA) Foundation in forming strategic partnerships with the scientific research community and pharmaceutical developers to transform the trajectory... View Details
Keywords: Innovation and Invention; Strategy; Business or Company Management; Society; Health; Public Administration Industry; Health Industry; United States
Chandra, Amitabh, Spencer Lee-Rey, and Caroline Marra. "The SMA Foundation: Steering Therapeutic Research and Development in a Rare Disease." Harvard Business School Case 621-112, May 2021.
- May 2021
- Case
Endeavor Kenya: Building an Entrepreneurial Ecosystem
By: Lynda M. Applegate, Shikhar Ghosh and Christian Godwin
In 2016, Fiona Mungai became Endeavor Kenya’s first managing director. In this role, she helped the organization build its inaugural board and select its first Endeavor entrepreneur, a fintech company called Cellulant. Throughout this process, Mungai observed the power... View Details
Keywords: Business Ventures; Entrepreneurship; Human Resources; Leadership; Leading Change; Management; Growth and Development Strategy; Negotiation; Economy; Markets; Emerging Markets; Network Effects; Relationships; Strategy; Financial Services Industry; Technology Industry; Telecommunications Industry; Shipping Industry; Agriculture and Agribusiness Industry; Africa; Kenya
Applegate, Lynda M., Shikhar Ghosh, and Christian Godwin. "Endeavor Kenya: Building an Entrepreneurial Ecosystem." Harvard Business School Case 821-038, May 2021.
- May–June 2021
- Article
Why Start-ups Fail
If you’re launching a business, the odds are against you: Two-thirds of start-ups never show a positive return. Unnerved by that statistic, a professor of entrepreneurship at Harvard Business School set out to discover why. Based on interviews and surveys with hundreds... View Details
Eisenmann, Thomas R. "Why Start-ups Fail." Harvard Business Review 99, no. 3 (May–June 2021): 76–85.
- April 22, 2021
- Article
Shareholders Are Pressing for Climate Risk Disclosures. That's Good for Everyone
By: Caroline Flammer, Michael W. Toffel and Kala Viswanathan
Does shareholder activism induce firms to voluntarily disclose climate change risks? And how do markets respond to these disclosures? New research finds that the extent of climate-risk disclosure increases by approximately 4.6% for each environment-related proposal... View Details
Keywords: Reporting; Transparency; Activism; Shareholder Activism; Shareholder Engagement; Climate Change; Corporate Disclosure; Investment Activism; Business and Shareholder Relations
Flammer, Caroline, Michael W. Toffel, and Kala Viswanathan. "Shareholders Are Pressing for Climate Risk Disclosures. That's Good for Everyone." Harvard Business Review Digital Articles (April 22, 2021).
- April 2021
- Case
ClearChoice Dental Implant Centers
By: Robert S. Kaplan, Ashiana Jivraj and Jane Barrow
The case illustrates the application of value-based health care to dental medicine. ClearChoice Dental Implant Centers was a rapidly-growing network of dentist-owned independent implant clinics. The targeted market included 23 million people, 15% of the US adult... View Details
Keywords: Value-based Health Care; Dental Medicine; Growth and Development Strategy; Expansion; Business Strategy; Customer Value and Value Chain; Customer Focus and Relationships; Health Industry; United States
Kaplan, Robert S., Ashiana Jivraj, and Jane Barrow. "ClearChoice Dental Implant Centers." Harvard Business School Case 121-082, April 2021.
- April 2021
- Case
The Clean Network and the Future of Global Technology Competition
By: Meg Rithmire and Courtney Han
In May 2019, amidst of an ever-worsening trade war between the U.S. and China, President Donald Trump added Chinese telecom giant Huawei to the Department of Commerce’s “entity list,” essentially forbidding American firms from doing business with the company. Huawei,... View Details
Keywords: 5G; Telecommunications; Information Technology; Internet and the Web; Mobile and Wireless Technology; Trade; Competition; International Relations; Telecommunications Industry; China
Rithmire, Meg, and Courtney Han. "The Clean Network and the Future of Global Technology Competition." Harvard Business School Case 721-045, April 2021.