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Show Results For
- All HBS Web
(1,491)
- People (6)
- News (556)
- Research (471)
- Events (3)
- Multimedia (5)
- Faculty Publications (148)
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- 2025
- Working Paper
Too Much, Too Soon? Early Funding, Technological Unconventionality, and Innovation Capabilities
By: Harsh Ketkar and Maria Roche
The availability of financial resources significantly shapes firm innovation outcomes, especially for early-stage,
innovation-focused technology firms. However, prior research has provided conflicting findings about this
relationship: On the one hand, resource... View Details
Keywords: Startups; Technology Strategy; Novelty; Unconventionality; Resource Constraints; Early Stage Firms; Business Startups; Technological Innovation; Entrepreneurial Finance
Ketkar, Harsh, and Maria Roche. "Too Much, Too Soon? Early Funding, Technological Unconventionality, and Innovation Capabilities." Harvard Business School Working Paper, No. 25-032, December 2024. (Revised February 2025.)
- 13 Aug 2008
- Research & Ideas
The Inner Life of Leaders
To what extent does a leader's inner life affect his or her behavior and actions toward other people? HBS professor emeritus Abraham Zaleznik, skilled in the practice of psychoanalysis and an admirer of the insights of Sigmund Freud, is... View Details
Keywords: by Martha Lagace
- 25 Mar 2019
- Research & Ideas
The Secret Life of Supply Chains
everything they do. “New technologies in the supply chain, such as artificial intelligence, have the capacity to similarly ripple through the economy in a way that consumer products simply can’t.” The supply chain economy leads to... View Details
- March 2023
- Case
Azenta Life Sciences: The Road to Transformation
By: Gary P. Pisano and Catherine Piner
When the Board brought Steve Schwartz in as President of Brooks Automation in 2010, they gave him a clear mission: strengthen the company’s core semiconductor equipment business and find a new industry to enter. Over the course of the next decade, Schwartz and the... View Details
Keywords: Transformation; Business and Shareholder Relations; Market Entry and Exit; Organizational Change and Adaptation; Segmentation; Technology Industry
Pisano, Gary P., and Catherine Piner. "Azenta Life Sciences: The Road to Transformation." Harvard Business School Case 623-066, March 2023.
- 06 Jan 2014
- Research & Ideas
Technology Re-Emergence: Creating New Value for Old Innovations
Out with the old, in with the new! That's the natural path of innovation. PCs killed typewriters, for instance. Smartphones superseded telephones, pocket calculators, and point-and-shoot cameras. Every once in a while, though, an old View Details
- October 2009 (Revised August 2014)
- Case
Tengion: Bringing Regenerative Medicine to Life
By: Elie Ofek and Polly Ross Ribatt
Tengion is a young biotech company that is at the frontier of regenerative medicine—a nascent field that seeks to promote the creation of new cells and tissue to repair or replace tissue or organ function lost due to age, disease, damage, or congenital defects. In late... View Details
Keywords: Decision Choices and Conditions; Financial Crisis; Entrepreneurship; Health Care and Treatment; Technological Innovation; Product Launch; Product Development; Research and Development; Biotechnology Industry; United States
Ofek, Elie, and Polly Ross Ribatt. "Tengion: Bringing Regenerative Medicine to Life." Harvard Business School Case 510-031, October 2009. (Revised August 2014.)
- February 2024
- Technical Note
AI Product Development Lifecycle
By: Michael Parzen, Jessie Li and Marily Nika
In this article, we will discuss the concept of AI Products, how they are changing our daily lives, how the field of AI & Product Management is evolving, and the AI Product Development Lifecycle. View Details
Keywords: Artificial Intelligence; Product Management; Product Life Cycle; Technology; AI and Machine Learning; Product Development
Parzen, Michael, Jessie Li, and Marily Nika. "AI Product Development Lifecycle." Harvard Business School Technical Note 624-070, February 2024.
- August 2023 (Revised January 2024)
- Case
Three Vignettes of Early Careers in the Life Sciences
By: Satish Tadikonda, Jacqueline Grant and William Marks
The case showcases three vignettes of career choice scenarios facing new graduates. How one navigates and handles these situations can have a significant impact on careers overall, with each vignette representing a situation likely to be experienced by most students in... View Details
Tadikonda, Satish, Jacqueline Grant, and William Marks. "Three Vignettes of Early Careers in the Life Sciences." Harvard Business School Case 824-054, August 2023. (Revised January 2024.)
- November 2019 (Revised April 2020)
- Technical Note
The Life Sciences Revolution: A Technical Primer
By: Gary P. Pisano, William J. Anderson, Amitabh Chandra, Clarissa Ceruti and Stephanie Oestreich
For more than two decades, scientific advances have been driving profound changes in drug discovery and the drug industry itself. This case provides an overview and description of these technical and scientific advances. Written for the nonscientific reader, it may be... View Details
Keywords: Science; Technological Innovation; Technology; Pharmaceutical Industry; Biotechnology Industry
Pisano, Gary P., William J. Anderson, Amitabh Chandra, Clarissa Ceruti, and Stephanie Oestreich. "The Life Sciences Revolution: A Technical Primer." Harvard Business School Technical Note 620-054, November 2019. (Revised April 2020.)
- September 1991
- Case
Rethinking the Corporate Workplace: Case Managers at Mutual Benefit Life
By: Robert G. Eccles Jr.
In early 1991, a spirit of innovation and organizational change was in the air at Mutual Benefit Life, with the success of the new "case manager" program its most concrete manifestation. Using powerful computer workstations, case managers could see insurance... View Details
Keywords: Organizational Change and Adaptation; Technological Innovation; Change Management; Information Technology; Insurance; Human Resources; Insurance Industry
Eccles, Robert G., Jr. "Rethinking the Corporate Workplace: Case Managers at Mutual Benefit Life." Harvard Business School Case 492-015, September 1991.
- June 2021
- Case
Chris Ernst: Purpose, People, Progress
By: Boris Groysberg, Robert Cross, Robin Abrahams and Katherine Connolly Baden
Executive Chris Ernst uses a unique personal strategy to define his six life roles (spiritual explorer, natural being, development pioneer, global/local citizen, thriving family, true friend) and achieve harmony among them. View Details
Keywords: Self-awareness; Self-discovery; Self-affirmation; Life Satisfaction; Work-Life Balance; Identity; Personal Development and Career; Family and Family Relationships; Happiness; Technology Industry; United States
Groysberg, Boris, Robert Cross, Robin Abrahams, and Katherine Connolly Baden. "Chris Ernst: Purpose, People, Progress." Harvard Business School Case 421-097, June 2021.
- October 1998 (Revised December 1999)
- Case
Gene Research, the Mapping of Life and the Global Economy
By: Ray A. Goldberg and Juan Enriquez-Cabot
A new firm is being created to speed up the process of mapping humans, animals, and plants by combining gene technology with rapid gene identification to improve the health and well being of the human population and the productivity of crops and animals. How does one... View Details
Keywords: Information Technology; Organizational Structure; Technological Innovation; Business Processes; Health Care and Treatment; Performance Productivity; Welfare; Agribusiness; Genetics; Science-Based Business; Biotechnology Industry; Agriculture and Agribusiness Industry
Goldberg, Ray A., and Juan Enriquez-Cabot. "Gene Research, the Mapping of Life and the Global Economy." Harvard Business School Case 599-016, October 1998. (Revised December 1999.)
- 2011
- Book
Detour: My Unexpected, Amazing, Life Changing Journey With OnStar
By: Chet Huber
Detour is the story behind the launch of OnStar’s now well known blue button, as told through the eyes of its founder and CEO of over fourteen years, Chet Huber. It’s a personal narrative that describes the events that led up to General Motors’ unexpected choice... View Details
Keywords: General Motors; OnStar; Technological Innovation; Business Startups; Transportation; Safety; Personal Development and Career; Creativity; Success; Business History; Auto Industry
Huber, Chet. Detour: My Unexpected, Amazing, Life Changing Journey With OnStar. CreateSpace Independent Publishing Platform, 2011.
- 23 Jun 2023
- HBS Case
This Company Lets Employees Take Charge—Even with Life and Death Decisions
Is it possible to truly empower employees to make their own decisions—even when those decisions could mean life or death? That is the question posed by Dutch home healthcare organization Buurtzorg, which has radically avoided almost all... View Details
- January 2000 (Revised October 2000)
- Case
Staples: A Year in the Life of a Start-Up
By: Myra M. Hart
The case provides information on the development of the office superstore concept, building partnerships, creating the business plan, and recruiting a management team. Focuses on the detailed level of decision making required to transform an idea into a viable... View Details
Keywords: Business Startups; Partners and Partnerships; Business Strategy; Recruitment; Management Teams; Integration; Information Technology; Entrepreneurship; Business Plan; Decision Making
Hart, Myra M. "Staples: A Year in the Life of a Start-Up." Harvard Business School Case 800-241, January 2000. (Revised October 2000.)
- December 2003 (Revised May 2004)
- Case
Blockbuster Inc. & Technological Substitution (A): Achieving Dominance in the Video Rental Industry
Provides a comprehensive background of the video rental industry and home entertainment giant, Blockbuster Inc. Follows the life of Blockbuster Inc. from its first days under founder Wayne Huizenga to its most recent developments under 2003 CEO John Antioco. By looking... View Details
Keywords: Risk and Uncertainty; Decisions; Technological Innovation; Competition; Change Management; Economics; Service Industry; Motion Pictures and Video Industry
Coughlan, Peter J., and Jenny Illes. "Blockbuster Inc. & Technological Substitution (A): Achieving Dominance in the Video Rental Industry." Harvard Business School Case 704-404, December 2003. (Revised May 2004.)
- August 2021
- Case
Mylestone: Can Multiple Pivots Preserve the Life of a Death Tech Startup?
By: Shikhar Ghosh and Marilyn Morgan Westner
Dave Balter and Jim Myers co-founded Mylestone, a death tech startup that applied technology to transform how grieving people memorialize the dead. The startup addressed a cultural problem and promised to solve a pressing need in the antiquated, multi-billion dollar... View Details
Keywords: Pivot; Startup; Business Model; Cryptocurrency; Ethical Decision Making; Emotions; Growth and Development Strategy; Ethics; Market Entry and Exit; Customer Relationship Management; Loss; Change Management; Relationships
Ghosh, Shikhar, and Marilyn Morgan Westner. "Mylestone: Can Multiple Pivots Preserve the Life of a Death Tech Startup?" Harvard Business School Case 822-018, August 2021.
- September 2013 (Revised August 2014)
- Case
Claritas Genomics
By: Robert F. Higgins and Matthew Preble
Claritas Genomics was formed in January 2013 when BCH spun out its Genetics Diagnostic Lab into a fully commercial entity. Claritas offered over 100 genomic tests to detect a range of conditions, including autism and intellectual disabilities, and was developing new... View Details
Keywords: Boston Children's Hospital; Genetic Engineering; Genetically Modified; Genetics Diagnostics; Health Care Industry; Healthcare IT; Healthcare Technology; Healthcare Ventures; Biomedical Research; Patrice Milos; Genomics; Genomic Testing; Life Technologies; Health Care and Treatment; Information Technology; Information Management; Genetics; Information Technology Industry; Information Technology Industry; Information Technology Industry; Boston; Massachusetts; United States
Higgins, Robert F., and Matthew Preble. "Claritas Genomics." Harvard Business School Case 814-032, September 2013. (Revised August 2014.)
- December 2005 (Revised October 2013)
- Case
Fred Khosravi and AccessClosure (A)
By: Richard Hamermesh and Liz Kind
Fred Khosravi is a serial medical device entrepreneur. In his latest venture, he must decide whether to sell now or continue to develop his current product and whether to market it, sell the company, or IPO. View Details
Keywords: Negotiation; Medical Devices; Venture Capital; Life Sciences; Health Care Industry; Healthcare Technology; Healthcare Ventures; Business Startups; Decision Choices and Conditions; Entrepreneurship; Growth and Development Strategy; Medical Devices and Supplies Industry; United States
Hamermesh, Richard, and Liz Kind. "Fred Khosravi and AccessClosure (A)." Harvard Business School Case 806-044, December 2005. (Revised October 2013.)
- January 2018
- Article
Big Data and Big Cities: The Promises and Limitations of Improved Measures of Urban Life
By: Edward L. Glaeser, Scott Duke Kominers, Michael Luca and Nikhil Naik
New, "big" data sources allow measurement of city characteristics and outcome variables at higher frequencies and finer geographic scales than ever before. However, big data will not solve large urban social science questions on its own. Big data has the most value for... View Details
Glaeser, Edward L., Scott Duke Kominers, Michael Luca, and Nikhil Naik. "Big Data and Big Cities: The Promises and Limitations of Improved Measures of Urban Life." Economic Inquiry 56, no. 1 (January 2018): 114–137.