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      • February 2022
      • Article

      Taxation and Innovation in the 20th Century

      By: Ufuk Akcigit, John Grigsby, Tom Nicholas and Stefanie Stantcheva
      This paper studies the effect of corporate and personal taxes on innovation in the United States over the twentieth century. We build a panel of the universe of inventors who patent since 1920, and a historical state-level corporate tax database with corporate tax... View Details
      Keywords: Innovation; Income Taxes; Corporate Taxation; Firms; Inventors; State Taxation; Business Taxation; R&D Tax Credits; Taxation; Innovation and Invention; History; United States
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      Akcigit, Ufuk, John Grigsby, Tom Nicholas, and Stefanie Stantcheva. "Taxation and Innovation in the 20th Century." Quarterly Journal of Economics 137, no. 1 (February 2022): 329–385.
      • January 2021
      • Supplement

      Takeda Pharmaceutical Company Limited (B)

      By: David J. Collis, Nobuo Sato and Akiko Kanno
      This case is a follow up to HBS Case No. 721-373, Takeda Pharmaceutical Company Limited (A). Following the events of the previous case, Takeda reached an agreement to acquire Ireland-based Shire Plc. The case follows some of the achievements and challenges Takeda and... View Details
      Keywords: Pharmaceutical Companies; Pharmaceuticals; M&A; Mergers & Acquisitions; Biotech; Biotechnology; R&D; Talent Management; Mergers and Acquisitions; Globalization; Global Strategy; Talent and Talent Management; Strategy; Biotechnology Industry; Pharmaceutical Industry; Japan; Asia
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      Collis, David J., Nobuo Sato, and Akiko Kanno. "Takeda Pharmaceutical Company Limited (B)." Harvard Business School Supplement 721-374, January 2021.
      • 2020
      • Working Paper

      Short-Termism, Shareholder Payouts, and Investment in the EU

      By: Jesse M. Fried and Charles C.Y. Wang
      Investor-driven “short-termism” is said to harm EU public firms' ability to invest for the long term, prompting calls for the EU to better insulate managers from shareholder pressure. But the evidence offered—in the form of rising levels of repurchases and dividends—is... View Details
      Keywords: Short-termism; Quarterly Capitalism; EU; Dividends; Equity Issuances; Equity Compensastion; Capital Flows; Capital Distribution; R&D; Innovation; Investment; Corporate Governance; Investment Return; Acquisition; European Union
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      Fried, Jesse M., and Charles C.Y. Wang. "Short-Termism, Shareholder Payouts, and Investment in the EU." Harvard Business School Working Paper, No. 21-054, October 2020.
      • March 2018 (Revised September 2023)
      • Case

      X: The Foghorn Decision

      By: Robert S. Huckman, Karim R. Lakhani and Kyle R. Myers
      In February 2016, Kathy Hannun—a project leader at X, Alphabet Inc.'s so-called "moonshot factory"—had to prepare a recommendation for the senior leadership of X regarding the future of Foghorn, a project she was leading to develop a carbon-neutral process for... View Details
      Keywords: Innovation; R&D Project Management; Radical Innovation; Clean Technology; Innovation and Management; Technological Innovation; Energy; Research and Development; Projects; Management; Decision Choices and Conditions; Technology Industry; Energy Industry; Green Technology Industry; California
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      Huckman, Robert S., Karim R. Lakhani, and Kyle R. Myers. "X: The Foghorn Decision." Harvard Business School Case 618-060, March 2018. (Revised September 2023.)
      • Article

      Lessons From Hollywood: A New Approach To Funding R&D

      By: Gary P. Pisano and Andrew W. Lo
      Companies find it increasingly difficult to justify long-term, risky R&D investments—particularly in science-based fields such as biotechnology, advanced materials, and energy. We argue in this article that the traditional venture model has limits for such investments... View Details
      Keywords: Financial Innovation; Financial Strategy; Project Management; R&D; Start-up; Innovation Strategy; Business Model; Research and Development; Financial Management; Risk Management; Strategy
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      Pisano, Gary P., and Andrew W. Lo. "Lessons From Hollywood: A New Approach To Funding R&D." MIT Sloan Management Review 57, no. 2 (Winter 2016): 47–54.
      • December 2016 (Revised December 2018)
      • Case

      From Start-Up to Grown-Up Nation: The Future of the Israeli Innovation Ecosystem

      By: Elie Ofek and Margot Eiran
      In June 2016, Benjamin (Bibi) Netanyahu, Prime Minister of Israel, wrestled with how to sustain Israel’s strong innovation track record and the country’s reputation as the “startup nation.” Despite the economic miracle the country had wrought since its founding, he... View Details
      Keywords: Israel; Israeli Start-up Nation; Innovation Economy; Entrepreneurial Mindset; Scaling-up; Unicorns; Innovation Clusters; High-tech; Innovation Management; Multinational Corporation R&D Centers; Social Equality; Two-tier Economy; Liberalizing An Economy; Foreign Investment; Military Service; Quality Of Human Capital; Socioeconomic Gaps; Labor Force Participation; Government Initiatives; Innovation and Management; Entrepreneurship; Venture Capital; Business Startups; Government and Politics; Economy; Equality and Inequality; Education; Resource Allocation; Globalization; Israel
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      Ofek, Elie, and Margot Eiran. "From Start-Up to Grown-Up Nation: The Future of the Israeli Innovation Ecosystem." Harvard Business School Case 517-066, December 2016. (Revised December 2018.)
      • November 2016
      • Case

      Transformation at Eli Lilly & Co. (A)

      By: William R. Kerr and Alexis Brownell
      Faced with the imminent loss of 40% of its revenues due to patent expirations, pharma giant Eli Lilly sets out on a dramatic transformation process in 2009. The case considers how Lilly restructured the organization into business areas to aid better decision-making,... View Details
      Keywords: Eli Lilly; Restructuring; R&D; Transformation; Organizational Change and Adaptation; Organizational Structure; Pharmaceutical Industry; Indianapolis
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      Kerr, William R., and Alexis Brownell. "Transformation at Eli Lilly & Co. (A)." Harvard Business School Case 817-070, November 2016.
      • February 2015
      • Case

      TouchTunes and the Connected Digital Jukebox Platform

      By: Alan MacCormack and Noah Fisher
      The case describes innovation and new product development at TouchTunes, the leader in the Digital Jukebox market. In March 2013, after releasing its innovative "Virtuo" jukebox developed in collaboration with frog design, TouchTunes was at a crossroads. Having... View Details
      Keywords: Innovation; Design; R&D; Outsourcing; Platform Strategy; Digital Media; Digital Platforms; Growth and Development Strategy; Innovation and Invention; Product Development; Music Industry
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      MacCormack, Alan, and Noah Fisher. "TouchTunes and the Connected Digital Jukebox Platform." Harvard Business School Case 615-051, February 2015.
      • January 2015
      • Article

      Collaboration in Multi-Partner R&D Projects: The Impact of Partnering Scale and Scope

      By: Anant Mishra, Aravind Chandrasekaran and Alan MacCormack
      How can firms design collaboration structures for effective performance in R&D projects that involve multiple partners? To address this question, we examine the theoretical underpinnings of collaboration structures in multi-partner R&D projects—i.e., the scale and the... View Details
      Keywords: Multi-Partner R&D Projects; Empirical Research; New Development; Collaboration Structures; Partnering Scale And Scope; Partners and Partnerships; Infrastructure; Performance Capacity; Research and Development; Collaborative Innovation and Invention
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      Mishra, Anant, Aravind Chandrasekaran, and Alan MacCormack. "Collaboration in Multi-Partner R&D Projects: The Impact of Partnering Scale and Scope." Journal of Operations Management 33-34 (January 2015): 1–14.
      • April 2014
      • Case

      Merrimack Pharmaceuticals, Inc. (A)

      By: Amy C. Edmondson, Bethany S. Gerstein and Melissa Valentine
      In 2006, Merrimack Pharmaceuticals was a fast-growing biotechnology company. Its leadership team was divided over whether to keep R&D organized in functional departments or transition to interdisciplinary teams. As a small company, Merrimack's R&D organization had... View Details
      Keywords: Teamwork; Interdisciplinary Collaboration; R&D; Biotechnology; Complexity; Innovation Management; Organizational Design; Groups and Teams; Collaborative Innovation and Invention; Research and Development; Biotechnology Industry; Pharmaceutical Industry
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      Edmondson, Amy C., Bethany S. Gerstein, and Melissa Valentine. "Merrimack Pharmaceuticals, Inc. (A)." Harvard Business School Case 614-063, April 2014.
      • September 2013 (Revised November 2015)
      • Case

      Living Proof: Are We a Technology Company or a Beauty Company?

      By: Willy Shih

      Jon Flint came up with the idea of a science-based beauty company while talking with his hairdresser about the problems with typical hair and skin care products. Together with a small team that included Professor Robert Langer of MIT, he committed to assemble a team... View Details

      Keywords: Hair Care; Personal Care; Science-based; R&D; Innovation and Invention; Innovation and Management; Innovation Leadership; Innovation Strategy; Technological Innovation; Marketing; Marketing Strategy; Product Marketing; Product Positioning; Science-Based Business; Business Strategy; Commercialization; Corporate Strategy; Technology Platform; Expansion; Beauty and Cosmetics Industry; United States; Boston; Cambridge
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      Shih, Willy. "Living Proof: Are We a Technology Company or a Beauty Company?" Harvard Business School Case 614-013, September 2013. (Revised November 2015.)
      • November 2012
      • Case

      The Universalization of L'Oréal

      By: Rajiv Lal and Carin-Isabel Knoop
      In 2010, half of the world's cosmetics sales came from the so-called emerging markets for the first time; L'Oréal opened three new subsidiaries, in Egypt, Pakistan, and Kazakhstan; and the Paris, France-based cosmetics and personal care powerhouse declared its... View Details
      Keywords: Retailing; Marketing; Cosmetics Industry; L'Oreal; India; R&D; Globalization; Product Development; Research and Development; Emerging Markets; Retail Industry; Latin America; Asia; Middle East
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      Lal, Rajiv, and Carin-Isabel Knoop. "The Universalization of L'Oréal." Harvard Business School Case 513-001, November 2012.
      • November 2012
      • Case

      CSIRO: The Light Metals Flagship Decision

      By: Willy Shih, Margaret P. Pierson and Dawn Lau
      This case explores the challenge of investing in basic research as a public good. CSIRO was Australia's leading science and research agency, and it was chartered to enhance national prosperity through R&D. Its Flagships program was designed to align research interests... View Details
      Keywords: R&D; Basic Research; Government-funded Research; Public Goods; Extractive Industries; Metals; Metals Processing; Decision Choices and Conditions; Decisions; Globalized Markets and Industries; Growth and Development; Innovation Strategy; Technological Innovation; Research and Development; Science-Based Business; Technology Adoption; Technology Platform; Manufacturing Industry; Mining Industry; Oceania; Australia
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      Shih, Willy, Margaret P. Pierson, and Dawn Lau. "CSIRO: The Light Metals Flagship Decision." Harvard Business School Case 613-029, November 2012.
      • October 2012 (Revised February 2014)
      • Teaching Note

      Logoplaste: Global Growing Challenges (TN)

      By: Juan Alcacer
      The case follows Logoplaste in its transformation from a small player in the plastic container industry in Portugal to a mid-sized global firm with operations in 11 countries. The case summarizes Logoplaste's history, with an emphasis on the milestones of its global... View Details
      Keywords: R&D; Innovation; Competitive Advantage; Operations Strategy; Global Strategy; Competition; Operations; Strategy; Manufacturing Industry
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      Alcacer, Juan. "Logoplaste: Global Growing Challenges (TN)." Harvard Business School Teaching Note 713-446, October 2012. (Revised February 2014.)
      • June 2012
      • Case

      Microsoft IT India

      By: Willy C. Shih, Margaret Pierson, Alexander Down, William Gustave Jair-Shemuel Jurist, Diego Medicina and Helen Wang
      Raj Biyani faced tough challenges managing Microsoft IT India: leading a remote development organization in which key decisions were made in Redmond, and managing an organization that was perceived as less strategic than its sister Microsoft India Development Center... View Details
      Keywords: Organizational Development; Cross-functional Management; Foreign Subsidiaries; Strategy Alignment; Organizational Behavior; Indian Software Development; Global Distributed R&D; Software Industry; Organizational Structure; Research and Development; Operations; Leadership; Globalized Firms and Management; Business Subsidiaries; Information Technology; Applications and Software; Technology Industry; India
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      Shih, Willy C., Margaret Pierson, Alexander Down, William Gustave Jair-Shemuel Jurist, Diego Medicina, and Helen Wang. "Microsoft IT India ." Harvard Business School Case 612-078, June 2012.
      • June 2012 (Revised July 2012)
      • Case

      Business-driven Research at IBM Research India

      By: Willy Shih, Margaret Pierson, Pankaj Agarwal, Diego Medicina and Juan Prajogo
      What is the right mix between business-driven and pure research? This case considers the question in the setting of IBM Research India, where a management push for balance between exploratory research and the fulfillment of business needs meets some resistance from... View Details
      Keywords: R&D; Computer Services Industries; IT R&D; Internet; Web-enabled Application; Technological Planning; Emerging Technologies; Information Technology; Internet and the Web; Research and Development; Projects; Practice; India
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      Shih, Willy, Margaret Pierson, Pankaj Agarwal, Diego Medicina, and Juan Prajogo. "Business-driven Research at IBM Research India ." Harvard Business School Case 612-076, June 2012. (Revised July 2012.)
      • April 2012
      • Case

      Bella Healthcare India

      By: Dorothy Leonard and Sunru Yong
      Bella Healthcare India was originally established in Bangalore as a low-cost manufacturing facility for a U.S.-based cardiology equipment developer. Under country manager Joseph Cherian it evolved considerably, developing its own research and development capabilities.... View Details
      Keywords: India; Productivity; Organizational Development; International Business; R&D; Cross-cultural Relations; Medical Equipment & Devices; Joint Ventures; Medical Specialties; Research and Development; Product Development; Organizational Change and Adaptation; Strategy; Decision Choices and Conditions; Health Care and Treatment; Product Launch; Failure; Cross-Cultural and Cross-Border Issues; Medical Devices and Supplies Industry; Bangalore
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      Leonard, Dorothy, and Sunru Yong. "Bella Healthcare India." Harvard Business School Brief Case 124-440, April 2012.
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