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  • April 18, 2022
  • Article

Will mRNA Technology Companies Spawn Innovation Ecosystems?

By: Christoph Grimpe, Timo Minssen, W. Nicholson Price, II and Ariel Dora Stern
The mRNA technologies that helped rapidly create effective COVID-19 vaccines could become technology platform businesses, which has tremendous implications for players in the world of drug development. These platforms could attract other companies interested in... View Details
Keywords: Health Care; Digital Health; Technology; Innovation; Health Care and Treatment; Technological Innovation; Digital Transformation; Health Industry; United States
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  • Article

Ein Booster für die Pharmabranche [A Booster for the Pharmaceutical Industry]

By: Ariel Dora Stern, Timo Minssen, W. Nicholson Price, II and Christoph Grimpe
mRNA technology has just helped to develop vaccines against COVID-19. Now, like Apple's iOS, it could provide the basis for new innovation platforms. View Details
Keywords: mRNA; COVID-19; Vaccines; Health Care and Treatment; Health Pandemics; Innovation and Invention; Health Industry
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  • October 2022
  • Case

Afrigen Biologics: Vaccines for the Global South

By: Debora L. Spar and Julia Comeau
The majority of vaccines used on the continent of Africa (99%) are produced offshore. This makes African nations reliant on the West for major health care needs, a problem which was exacerbated by the COVID-19 pandemic. Afrigen Biologics (in partnership with the WHO)... View Details
Keywords: Vaccination; Vaccine; mRNA; COVID; COVID-19; Inequity; Hub-and-spoke; Health Care and Treatment; Health Pandemics; Production; Social Issues; Business and Government Relations; South Africa; Africa
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  • 2025
  • Working Paper

Technology Choice, Spillovers, and the Concentration of R&D

By: Todd A. Lensman
The direction of innovation shapes both current technologies and future innovation opportunities, as firms acquire expertise and create public knowledge through discovery. But how do firms choose which technologies to develop? Do they ever fail to exploit... View Details
Keywords: Economic Growth; Innovation Strategy; Research and Development
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  • May 2025 (Revised June 2025)
  • Supplement

Michael Ku and Global Clinical Supply at Pfizer Inc.: Bringing Hope to Patients (D)

By: Linda A. Hill and Lydia Begag
This fourth installment in the Pfizer Global Clinical Supply (GCS) transformation case series highlights how over a decade of cultural and digital evolution positioned GCS to meet unprecedented global challenges. In 2011, Michael Ku became the Vice President of GCS and... View Details
Keywords: Innovation Leadership; Technological Innovation; Leadership Development; Leadership Style; Research and Development; Science-Based Business; Transformation; Health Pandemics; AI and Machine Learning; Analytics and Data Science; Digital Transformation; Leading Change; Product Launch; Supply Chain; Organizational Change and Adaptation; Alignment; Pharmaceutical Industry; Biotechnology Industry; Health Industry; United States; Asia; Europe; Latin America
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  • Web

Latin America - Global

culture of innovation before leading the organization through a digital transformation. This groundwork proved invaluable during the COVID-19 crisis, as GCS delivered Pfizer’s mRNA vaccine in just 266 days, maintained continuity across... View Details
  • Web

Your Alumni Community - Alumni

to people through mRNA medicines. HBS CPD @hbscpd A glimpse at the speaker lineup for reunion. For more info on reunion—including additional faculty speakers & alumn twitter.com/i/web/status/1 Apr 24 2023, 09:00 PM HBS Alumni @HBSAlumni... View Details
  • Portrait Project

Albert Chiu

COVID-19. As a chemical engineer, I designed the process to manufacture Moderna and Pfizer’s mRNA COVID-19 vaccines. I developed new technologies to improve how vaccines are manufactured and shortened production time in half for Operation... View Details
  • 31 Jan 2014
  • News

Body, Heal Thyself

molecules responsible for transporting DNA code from a cell's nucleus to the ribosomes that create proteins. mRNA Therapeutics, as the company calls this new drug application, gives patients' cells the code they need to begin creating... View Details
Keywords: Maureen Harmon; biotech; Health, Social Assistance; Scientific Research and Development Services
  • 25 Apr 2014
  • News

A revolution in healing

proteins. Moderna's mRNA Therapeutics gives patients' cells the code they need to begin creating their own proteins and antibodies to fight disease, allowing the body to heal itself. "We believe we have a chance to do something... View Details
  • 24 Sep 2020
  • News

The Race for a Vaccine

most companies, the financial risk remained too high to justify the potential reward—a situation that too often led to dangerous vaccine shortages. It was at this moment that Moderna turned its attention to vaccines. The company had been founded in 2010 with the... View Details
Keywords: April White; COVID-19; Scientific Research and Development Services
  • 19 Jan 2022
  • In Practice

7 Trends to Watch in 2022

As 2022 gets underway we asked our faculty to highlight some trends worth watching in the coming year. Ariel Stern: A new future for digital health care While 2020 and 2021 were years of rapid innovation and deployment of new health care technologies and delivery... View Details
Keywords: by HBS News
  • 06 Dec 2021
  • News

What's the Word?

allowing users to retain relative anonymity. Back to top Bi·o·rev·o·loo·shun (noun) As the months of the pandemic ticked by, many of us were transfixed by progress updates on vaccine development. Moderna’s mRNA technology, we learned,... View Details
Keywords: Julia Hanna; illustrations by Martha Rich; Manufacturing; Finance; News, Library, Internet, and Other Services; Information