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- May 2025
- Teaching Note
The VideaHealth AI Factory: CEO Florian Hillen on Speed, Scale, and Innovation
By: Tsedal Neeley
Teaching Note for HBS Case No. 425-720. Florian Hillen, co-founder and CEO of VideaHealth, a startup using artificial intelligence (AI) to detect dental conditions on x-rays, spent the early years of his company laying the groundwork for an AI factory. This AI factory,... View Details
Keywords: Diagnostics; Organization Design; Change Management; Disruption; Transformation; Health Care and Treatment; AI and Machine Learning; Technological Innovation; Technology Adoption; Disruptive Innovation; Management Style; Organizational Culture; Success; Adoption; Technology Industry; Health Industry; United States
- March 2025
- Case
Niramai: An AI Solution to Save Lives
By: Rembrand Koning, Maria P. Roche and Kairavi Dey
Founded in 2017, Niramai developed Thermalytix, a breast cancer screening tool. Thermalytix used a high-resolution thermal sensing device and machine learning algorithms to analyze thermal images and detect tumors. Its patented solution leveraged big data analytics,... View Details
- February 2025
- Article
Variation in Batch Ordering of Imaging Tests in the Emergency Department and the Impact on Care Delivery
By: Jacob C. Jameson, Soroush Saghafian, Robert S. Huckman and Nicole Hodgson
Objectives: To examine heterogeneity in physician batch ordering practices and measure the impact of a physician's tendency to batch order imaging tests on patient outcomes and resource utilization.
Study Setting and Design: In this retrospective study, we used... View Details
Study Setting and Design: In this retrospective study, we used... View Details
Keywords: Health Care; Operations Management; Productivity; Health Care and Treatment; Operations; Outcome or Result; Resource Allocation; Health Industry; United States
Jameson, Jacob C., Soroush Saghafian, Robert S. Huckman, and Nicole Hodgson. "Variation in Batch Ordering of Imaging Tests in the Emergency Department and the Impact on Care Delivery." Health Services Research 60, no. 1 (February 2025).
- February 2025
- Article
Innovations in Evaluating Ambulatory Costs of Cystic Fibrosis Care: A Comparative Study Across Multidisciplinary Care Centers in Ireland and the United States
By: Emma Brady, Ryan C. Perkins, Kate Cullen, Gregory S. Sawicki, Robert S. Kaplan and Gerardine Doyle
Lead clinicians at two large pediatric cystic fibrosis (CF) centers in the United States and Ireland measured and compared their ambulatory care costs. The clinicians selected three strata of patients (0–11 months, 1–5 years, and 6–17 years of age). Process maps were... View Details
Brady, Emma, Ryan C. Perkins, Kate Cullen, Gregory S. Sawicki, Robert S. Kaplan, and Gerardine Doyle. "Innovations in Evaluating Ambulatory Costs of Cystic Fibrosis Care: A Comparative Study Across Multidisciplinary Care Centers in Ireland and the United States." NEJM Catalyst Innovations in Care Delivery 6, no. 2 (February 2025).
- January 2025
- Case
The VideaHealth AI Factory: CEO Florian Hillen on Speed, Scale, and Innovation (A)
By: Tsedal Neeley, Levi Stroud, Ruth Page and Dave Habeeb
Pre-abstract:
This multimedia case should be assigned to students in advance of class. Instructors should consider the timing of making the (B) Case videos available to students, as they may reveal key case details.
Abstract: Florian Hillen, co-founder... View Details
Abstract: Florian Hillen, co-founder... View Details
Keywords: Diagnostics; Organization Design; Change Management; Disruption; Transformation; Health Care and Treatment; AI and Machine Learning; Technology Adoption; Technological Innovation; Management Style; Organizational Culture; Success; Technology Industry; Health Industry; United States
Neeley, Tsedal, Levi Stroud, Ruth Page, and Dave Habeeb. "The VideaHealth AI Factory: CEO Florian Hillen on Speed, Scale, and Innovation (A)." Harvard Business School Multimedia/Video Case 425-720, January 2025.
- January 2025
- Supplement
The VideaHealth AI Factory: CEO Florian Hillen on Speed, Scale, and Innovation (B)
By: Tsedal Neeley, Levi Stroud, Ruth Page and Dave Habeeb
Pre-abstract:
This multimedia case should be assigned to students in advance of class. Instructors should consider the timing of making the (B) Case videos available to students, as they may reveal key case details.
Abstract: Florian Hillen, co-founder... View Details
Abstract: Florian Hillen, co-founder... View Details
Keywords: Diagnostics; Organization Design; Change Management; Disruption; Transformation; Health Care and Treatment; AI and Machine Learning; Technology Adoption; Technological Innovation; Management Style; Organizational Culture; Success; Technology Industry; Health Industry; United States
Neeley, Tsedal, Levi Stroud, Ruth Page, and Dave Habeeb. "The VideaHealth AI Factory: CEO Florian Hillen on Speed, Scale, and Innovation (B)." Harvard Business School Multimedia/Video Supplement 425-721, January 2025.
- September 2024
- Case
Myeloma Investment Fund
By: Kyle Myers and Scott Sawaya
This case explores a critical decision facing the Myeloma Investment Fund (MIF) as it evaluates two investment opportunities aimed at accelerating a cure for multiple myeloma.
The MIF, a venture philanthropy fund, must choose between two distinct paths. One... View Details
The MIF, a venture philanthropy fund, must choose between two distinct paths. One... View Details
Keywords: Venture Philanthropy; Biomedical Research; Investing For Impact; Innovation & Entrepreneurship; Venture Capital; Science-Based Business; Philanthropy and Charitable Giving; Decision Making; Health Care and Treatment; Biotechnology Industry; Pharmaceutical Industry
Myers, Kyle, and Scott Sawaya. "Myeloma Investment Fund." Harvard Business School Case 625-047, September 2024.
- August 2024
- Case
Scaling Seven Starling
By: Ryan W. Buell and Carin-Isabel Knoop
Seven Starling, a maternal mental health startup, is scaling its digital clinic model. Seven Starling addresses perinatal mental health challenges by providing licensed therapists, peer support, and medication to mothers across five states, with a hybrid care model... View Details
Keywords: Business Model; Business Startups; Health Care and Treatment; Growth and Development Strategy; Mission and Purpose; Health Industry
Buell, Ryan W., and Carin-Isabel Knoop. "Scaling Seven Starling." Harvard Business School Case 625-046, August 2024.
- August 2024
- Case
Sky Therapeutics: Innovating in Digital Therapeutics
By: Satish Tadikonda, Olivia Reszczynski and William Marks
Shad Faraz and Alex Youssef were intrigued by the opportunities in the relatively new area of Digital Therapeutics. Despite initial successes, early entrants had struggled with reimbursement and revenue-predictability challenges. However, venture investors still... View Details
- June 2024
- Article
Enhancing Value and Well-Being: The Basket of Motivators Framework for Aligning Neurology Clinical Practices with Performance Outcomes
By: Peter N. Hadar, Susanna Gallani and Lidia Moura
Physician burnout, which is prevalent in neurology, has accelerated in recent years. While multifactorial, a major contributing factor to burnout is a payment model that rewards volume over quality, leaving physicians overburdened and unfulfilled. The aim of this... View Details
Keywords: Compensation and Benefits; Personal Development and Career; Well-being; Motivation and Incentives
Hadar, Peter N., Susanna Gallani, and Lidia Moura. "Enhancing Value and Well-Being: The Basket of Motivators Framework for Aligning Neurology Clinical Practices with Performance Outcomes." Neurology: Clinical Practice 14, no. 1 (June 2024).
- June 2024 (Revised August 2024)
- Case
Hospital for Special Surgery: Returning to a New Normal? (A)
By: Robert S. Huckman, Michael Lingzhi Li and Camille Gregory
Early on the morning of April 27, 2020, Justin Oppenheimer stood outside the entrance to the lobby of the Hospital for Special Surgery (HSS) Pavilion Building with mixed emotions. On one hand, Oppenheimer, HSS’ Enterprise Chief Operating Officer and Chief Strategy... View Details
Keywords: Operations Management; Scheduling; Optimization; COVID-19; Health Care and Treatment; Operations; Customer Focus and Relationships; Disruption; Health Industry; United States
Huckman, Robert S., Michael Lingzhi Li, and Camille Gregory. "Hospital for Special Surgery: Returning to a New Normal? (A)." Harvard Business School Case 624-092, June 2024. (Revised August 2024.)
- May 2024 (Revised February 2025)
- Case
Choosing the Course of Passion: Brooke Boyarsky Pratt at knownwell
By: Jon M. Jachimowicz and Alexis Lefort
Brooke Boyarsky Pratt (HBS ’13) enjoyed considerable success in her early career, quickly climbing the ranks to associate partner at McKinsey, and later becoming an executive vice president at Berkadia, a Berkshire Hathaway portfolio company. Throughout these years,... View Details
Keywords: Passion; Career; Career Planning; Purpose; Personal Development and Career; Mission and Purpose; Identity; Business Startups; Health Care and Treatment; Health Disorders; Growth and Development Strategy; Market Entry and Exit; Health Industry; United States
Jachimowicz, Jon M., and Alexis Lefort. "Choosing the Course of Passion: Brooke Boyarsky Pratt at knownwell." Harvard Business School Case 424-040, May 2024. (Revised February 2025.)
- April 2024
- Case
Dr. Tom Mihaljevic and Cleveland Clinic
By: Linda A. Hill and Lydia Begag
In December 2022, Dr. Tomislav (“Tom”) Mihaljevic, CEO and President of Cleveland Clinic, was reflecting on the last few years at the hospital, marked both by unprecedented challenges and remarkable achievements. Cleveland Clinic had recently been ranked the world’s... View Details
Keywords: Recruitment; Retention; Analytics and Data Science; Digital Transformation; Digital Platforms; Innovation and Management; Innovation Leadership; Human Capital; Leadership Development; Leadership Style; Leading Change; Organizational Culture; Organizational Structure; Organizational Change and Adaptation; Mission and Purpose; Outcome or Result; Performance Evaluation; Health Pandemics; Goals and Objectives; Health Industry; Cleveland; London; Abu Dhabi; Florida; Ohio
Hill, Linda A., and Lydia Begag. "Dr. Tom Mihaljevic and Cleveland Clinic." Harvard Business School Case 424-031, April 2024.
- 18 Apr 2024
- Lecture
Innovation Opportunities Created by COVID-19 Can Help: And How to Make Them Happen
The crush of patients created by COVID enabled the creation of sites for care outside the traditional hospital, such as retail pharmacies, ambulatory surgery centers, urgent care centers, telemedicine, and wireless sensors. Public policy mirrored these changes by... View Details
- March–April 2024
- Article
Retailers and Health Systems Can Improve Care Together
By: Robert S. Huckman, Vivian S. Lee and Bradley R Staats
Health systems are struggling to address the many shortcomings of health care delivery: rapidly growing costs, inconsistent quality, and inadequate and unequal access to primary and other types of care. However, if retailers and health systems were to form strong... View Details
Keywords: Health Care; Retail; Retailers; Consumer; Health Care and Treatment; Value; Consumer Behavior; Business Model; Partners and Partnerships; Health Industry; Retail Industry; United States
Huckman, Robert S., Vivian S. Lee, and Bradley R Staats. "Retailers and Health Systems Can Improve Care Together." Harvard Business Review 102, no. 2 (March–April 2024): 120–127.
- February 2024
- Article
Representation and Extrapolation: Evidence from Clinical Trials
By: Marcella Alsan, Maya Durvasula, Harsh Gupta, Joshua Schwartzstein and Heidi L. Williams
This article examines the consequences and causes of low enrollment of Black patients in clinical
trials. We develop a simple model of similarity-based extrapolation that predicts that evidence is
more relevant for decision-making by physicians and patients when it... View Details
Keywords: Representation; Racial Disparity; Health Testing and Trials; Race; Equality and Inequality; Innovation and Invention; Pharmaceutical Industry
Alsan, Marcella, Maya Durvasula, Harsh Gupta, Joshua Schwartzstein, and Heidi L. Williams. "Representation and Extrapolation: Evidence from Clinical Trials." Quarterly Journal of Economics 139, no. 1 (February 2024): 575–635.
- January 2024
- Article
A Cost Model for a Low Threshold Clinic Treating Opioid Use Disorder
By: Sarah E. Wakeman, Elizabeth Powell, Syed Shehab, Grace Herman, Laura Kehoe and Robert S. Kaplan
The US fee-for-service payment system under-reimburses clinics offering access to comprehensive treatments for opioid use disorder (OUD). The funding shortfall limits a clinic’s ability to expand and improve access, especially for socially marginalized patients with... View Details
Wakeman, Sarah E., Elizabeth Powell, Syed Shehab, Grace Herman, Laura Kehoe, and Robert S. Kaplan. "A Cost Model for a Low Threshold Clinic Treating Opioid Use Disorder." Journal of Behavioral Health Services & Research 51, no. 1 (January 2024): 22–30.
- October 2023
- Case
Hey Jane: Delivering Abortion Pills to the Doorstep
By: Rembrand Koning, Geraldine Pena-Galea and Sarah Mehta
This case tells the story of Hey Jane, a telehealth clinic founded in 2020 that provides virtual medication abortion services to eligible patients in nine U.S. states. By January 2023, the company had served more than 20,000 patients and raised nearly $10 million in... View Details
Keywords: Operations; Business Startups; Health Care and Treatment; Growth and Development Strategy; Health Industry; Technology Industry; United States
Koning, Rembrand, Geraldine Pena-Galea, and Sarah Mehta. "Hey Jane: Delivering Abortion Pills to the Doorstep." Harvard Business School Case 724-408, October 2023.
- 2023
- Working Paper
The Political Economy of a 'Miracle Cure': The Case of Nebulized Ibuprofen and Its Diffusion in Argentina
By: Sebastian Calónico, Rafael Di Tella and Juan Cruz Lopez Del Valle
We document the diffusion of nebulized ibuprofen in Argentina as a treatment for COVID-19. As the pandemic spread, this clinically unsupported drug reached thousands of patients, even some seriously ill, despite warnings by the regulator and medical societies. Detailed... View Details
Keywords: COVID-19; Health Care and Treatment; Health Pandemics; Adoption; Behavior; Governing Rules, Regulations, and Reforms; Learning
Calónico, Sebastian, Rafael Di Tella, and Juan Cruz Lopez Del Valle. "The Political Economy of a 'Miracle Cure': The Case of Nebulized Ibuprofen and Its Diffusion in Argentina." NBER Working Paper Series, No. 31781, October 2023.
- October 2023
- Article
Health System Perspective on Cost for Delivering a Decision Aid for Prostate Cancer Using Time-Driven Activity-Based Costing
By: David R. Ho, Robert S. Kaplan, Jonathan Bergman, David F. Penson, Benjamin Waterman, Kristin C. Williams, Jefersson Villatoro, Lorna Kwan and Christopher S. Saigal
Previsit decision aids (DAs) have been shown to improve decisional quality. But the cost to deploy a DA has not been previously estimated. We interviewed or observed relevant personnel at three institutions that had implemented DA programs for men with prostate cancer.... View Details
Keywords: Time-Driven Activity-Based Costing; Health Care and Treatment; Cost Accounting; Health Industry
Ho, David R., Robert S. Kaplan, Jonathan Bergman, David F. Penson, Benjamin Waterman, Kristin C. Williams, Jefersson Villatoro, Lorna Kwan, and Christopher S. Saigal. "Health System Perspective on Cost for Delivering a Decision Aid for Prostate Cancer Using Time-Driven Activity-Based Costing." Medical Care 61, no. 10 (October 2023): 681–688.