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October 2020
Article

The Elasticity of Science

This paper identifies the degree to which scientists are willing to change the direction of their work in exchange for resources. Data from the National Institutes of Health are used to estimate how scientists respond to targeted funding opportunities. Inducing a... View Details

Keywords: Scientists; Funding; Research; Change

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September 2019
Case

Funding Sources for Science & Technology Start-ups in India

By: Tarun Khanna, Arjun Swarup and Rachna Tahilyani

India's start-up ecosystem is amongst the largest globally, with a variety of funding options from angel investors, venture capital and corporate venture capital to debt. Classic consumer focused start-ups which look to leverage technology have been able to raise... View Details

Keywords: Venture Capital; Business Startups; Science; Information Technology; Financial Services Industry; Banking Industry; Technology Industry; India; South Asia

2001
Chapter

Publicly Funded Science and the Productivity of the Pharmaceutical Industry

By: Rebecca Henderson and Ian Cockburn

U.S. taxpayers funded $14.8 billion of health related research last year, four times the amount that was spent in 1970 in real terms. In this paper we evaluate the impact of these huge expenditures on the technological performance of the pharmaceutical industry. While... View Details

Keywords: Public Sector; Science-Based Business; Research and Development; Sovereign Finance; Pharmaceutical Industry

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2020
Working Paper

Scientific Production: An Exploration into Organization, Resource Allocation, and Funding

By: Jerry Thursby, Marie Thursby, Karim R. Lakhani, Kyle R. Myers, Nina Cohodes, Sarah Bratt, Dennis Byrski, Hannah Cohoon and Maria Roche

Production of scientific knowledge is core to civilizational advancement in economic and material wellbeing of societies. Despite its fundamental importance, however, a systematic effort to quantitatively study the factors underlying scientific production, particularly... View Details

Keywords: Funding; Science; Knowledge; Research; Information Management; Resource Allocation

2014
Working Paper

Bridging Science and Technology Through Academic-Industry Partnerships

By: Sen Chai and Willy C. Shih

Scientific research and its translation into commercialized technology is a driver of wealth creation and economic growth. Partnerships to foster the translational processes from public research organizations, such as universities and hospitals, to private firms are a... View Details

Keywords: Innovation; Firm Performance; Public-private Partnership Funding; Translational Research; Small And Medium Enterprises; Partners and Partnerships; Public Sector; Private Sector; Performance; Science-Based Business; Innovation and Invention

March 2020 (Revised June 2022)
Case

GreenLight Fund

By: Brian Trelstad, Julia Kelley and Mel Martin

As Tara Noland, the Executive Director (ED) of GreenLight Cincinnati, reflected on her first few years on the job. Noland had delivered on what she had been hired to do in the city: work with leading philanthropists and nonprofit executives to use data and evidence to... View Details

Keywords: Philanthropy; Venture Philanthropy; Replication; Philanthropy and Charitable Giving; Venture Capital; Social Issues; Decision Making; Analytics and Data Science; Cincinnati

2015
Working Paper

Public R&D Investments and Private-sector Patenting: Evidence from NIH Funding Rules

By: Pierre Azoulay, Joshua S. Graff Zivin, Danielle Li and Bhaven N. Sampat

We quantify the impact of scientific grant funding at the National Institutes of Health (NIH) on patenting by pharmaceutical and biotechnology firms. Our paper makes two contributions. First, we use newly constructed bibliometric data to develop a method for flexibly... View Details

Keywords: Economics Of Science; Patenting; Academic Reserach; NIH; Knowledge Spillovers; Patents; Research; Government and Politics

September 2024
Case

Myeloma Investment Fund

By: Kyle Myers and Scott Sawaya

This case explores a critical decision facing the Myeloma Investment Fund (MIF) as it evaluates two investment opportunities aimed at accelerating a cure for multiple myeloma.

The MIF, a venture philanthropy fund, must choose between two distinct paths. One... View Details

Keywords: Venture Philanthropy; Biomedical Research; Investing For Impact; Innovation ＆ Entrepreneurship; Venture Capital; Science-Based Business; Philanthropy and Charitable Giving; Decision Making; Health Care and Treatment; Biotechnology Industry; Pharmaceutical Industry

2017
Mimeo

Science for Society: Science and Technology Based Social Entrepreneurship

By: Tarun Khanna, Shashank Shah and Kundan Madireddy

This publication is an outcome of the team's research, engagement and interactions with over 25 science and technology-based social enterprises in India. It provides details on the research process, insightful outcomes and innovative impact.
Throughout the... View Details

Keywords: Social Entrepreneurship; Science-Based Business; Information Technology; Business and Community Relations; India

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June 2016 (Revised January 2018)
Case

World Wildlife Fund (WWF)

By: Ramon Casadesus-Masanell and Jordan Mitchell

Nearly all environmental organizations have a similar aim: to stop the degradation of the natural environment. However, the strategies that environmental organizations choose to employ are sometimes starkly different. This case compares the models of two dissimilar... View Details

Keywords: Business Model; Business and Community Relations; Business and Government Relations; Environmental Sustainability; Non-Governmental Organizations; Business Strategy

November 2009 (Revised April 2010)
Case

Rose Smart Growth Investment Fund

By: Arthur I Segel and Justin Seth Ginsburgh

The Jonathan Rose Companies must decide how to design and launch an innovative new real estate fund focused on green and transit oriented properties. JRC seeks to show through the fund that smart growth and green buildings provide superior economic returns to sprawl... View Details

Keywords: Property; Buildings and Facilities; Transition; Financing and Loans; Investment Funds; Investment; Marketing; Energy Conservation; Business Strategy; Growth and Development Strategy; Environmental Sustainability; Finance; Real Estate Industry

June 2008 (Revised August 2008)
Case

World Wildlife Fund US

By: Jane Wei-Skillern and Kerry Herman

World Wildlife Fund US is a leading international conservation nonprofit that operates within a global network of WWF organizations. This case examines WWF US's strategy to achieve its mission of protecting natural wildlife and resources. In contrast to traditional... View Details

Keywords: Globalized Firms and Management; Partners and Partnerships; Environmental Sustainability; Nonprofit Organizations; Social and Collaborative Networks; Trust; Integration; Sumatra; United States

June 2006 (Revised January 2007)
Case

Dana Hall: Funding a Mission (A)

By: F. Warren McFarlan, Herman B. Leonard and Melissa Tritter

Dana Hall is a private all-girls school in New England facing a crisis in its mission. As social norms shift away from single-sex education, the school's enrollment is falling and deficits are becoming the norm. At the same time, the modern vision for girls' education... View Details

Keywords: Crisis Management; Financing and Loans; Nonprofit Organizations; Mission and Purpose; Strategic Planning; Education Industry; England

October 2012
Teaching Plan

Vertex Pharmaceuticals and the Cystic Fibrosis Foundation: Venture Philanthropy Funding for Biotech (TP)

By: Robert F. Higgins

This is the teaching note related to HBS case 808005. In 2001, Vertex Pharmaceuticals Incorporated acquired the San Diego-based biotech company, Aurora Biosciences. The combination of Vertex's and Aurora's technologies would improve the flow of novel drug candidates... View Details

Keywords: Venture Philanthropy; Biotechnology; Funding Philanthropy Venture; Cystic Fibrosis; Foundations; Pharmaceuticals; Mergers and Acquisitions; For-Profit Firms; Venture Capital; Philanthropy and Charitable Giving; Science-Based Business; Nonprofit Organizations; Pharmaceutical Industry; Biotechnology Industry; United States; San Diego

January 2019 (Revised February 2020)
Case

Should a Pension Fund Try to Change the World? Inside GPIF's Embrace of ESG

By: George Serafeim

In the fall of 2018, Hiro Mizuno, the Chief Investment Officer (CIO) of GPIF, the Japanese Government Pension Fund, was reflecting on his efforts to integrate Environmental, Social and Governance (ESG) issues into every aspect of GPIF’s portfolio. His efforts ranged... View Details

Keywords: Pension Funds; ESG (Environmental, Social, Governance) Performance; Investment Funds; Environmental Sustainability; Social Issues; Governance; Leading Change; Economy; Performance Improvement; Japan

July 2007 (Revised November 2009)
Case

World Wildlife Fund for Nature (WWF)

By: Ramon Casadesus-Masanell and Jordan Mitchell

Nearly all environmental organizations have a similar aim: to stop the degradation of the natural environment. However, the strategies which environmental organizations choose to employ are sometimes starkly different. Compares the models of two dissimilar... View Details

Keywords: Business Model; Business and Community Relations; Business and Government Relations; Environmental Sustainability; Non-Governmental Organizations; Business Strategy

September 2004 (Revised December 2004)
Case

Bank Leu's Prima Cat Bond Fund

In 2001, Bank Leu, a Swiss private bank, is considering creating the world's first public fund for catastrophe bonds. Cat bonds are securities whose payments depend on the probability of a catastrophe occurring, such as an earthquake or hurricane. Cat bonds are... View Details

Keywords: Risk Management; Bonds; Natural Disasters; Insurance; Capital Markets; Banks and Banking; Banking Industry; Insurance Industry; Switzerland

December 2004 (Revised February 2005)
Case

Cheetah Conservation Fund Bush Project, The

Laurie Marker, head of the Cheetah Conservation Fund, is trying to form a for-profit institution, the Bush Project, to control the bush encroachment problem in Namibia. Bush encroachment not only destroys the general ecosystem, but it also has a harmful impact on the... View Details

Keywords: Social Enterprise; For-Profit Firms; Emerging Markets; Environmental Sustainability; Financial Strategy; Africa

January 2018
Case

Environmental Technology Fund Partners and E-Leather

By: Vikram S. Gandhi and Aldo Sesia

It is 2014 and Environmental Technologies Fund (ETF) Partners, a UK-based venture capital firm, has an opportunity to invest in a privately held UK company that manufactured engineered composition leather extracted from waste leather using an environmentally friendly... View Details

Keywords: Sustainability; Venture Capital; Investment Strategy; Investment; Strategy; Ownership; Valuation; Energy Conservation; Equity; Technological Innovation; Environmental Sustainability; Performance Efficiency; Manufacturing Industry; Financial Services Industry; United Kingdom

11 Nov 2015
Working Paper Summaries

Public R&D Investments and Private-sector Patenting: Evidence from NIH Funding Rules

Keywords: by Danielle Li; Health; Biotechnology; Pharmaceutical; Medical Devices & Supplies

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