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  • Article

Patterns of Failure after Involved Field Radiation Therapy for Pediatric and Young Adult Hodgkin Lymphoma

By: Minh-Phuong Huynh-Le, Amanda J. Walker, Scott Duke Kominers, Ido Paz-Priel, Moody D. Wharam and Stephanie A. Terezakis
Involved field radiation therapy (IFRT) is integral in curative therapy for Hodgkin lymphoma (HL), although primarily used in patients with intermediate/high‐risk HL. We present failure patterns and clinical outcomes in a cohort of pediatric and young adult patients... View Details
Keywords: Hematology/oncology; Hodgkin Lymphoma; Involved Field Radiation Therapy; Health Disorders; Health Care and Treatment
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  • Article

Use of Crowd Innovation to Develop an Artificial Intelligence-Based Solution for Radiation Therapy Targeting

By: Raymond H. Mak, Michael G. Endres, Jin Hyun Paik, Rinat A. Sergeev, Hugo Aerts, Christopher L. Williams, Karim R. Lakhani and Eva C. Guinan
Importance: Radiation therapy (RT) is a critical cancer treatment, but the existing radiation oncologist work force does not meet growing global demand. One key physician task in RT planning involves tumor segmentation for targeting, which requires substantial... View Details
Keywords: Crowdsourcing; AI Algorithms; Health Care and Treatment; Collaborative Innovation and Invention; AI and Machine Learning
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  • September–October 2020
  • Article

The Past, Present, and (Near) Future of Gene Therapy and Gene Editing

By: Julia Pian, Amitabh Chandra and Ariel Dora Stern
Emerging gene therapy and gene-editing technologies will have a growing impact on patient lives and health-care delivery. We analyzed a decade of data on clinical trials and venture capital investments to understand the likely trajectory of genetically focused... View Details
Keywords: Gene Therapy; Gene Editing; Impact; Health Care and Treatment; Technological Innovation; Health Testing and Trials; Venture Capital; Change
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  • 18 Apr 2019
  • Research & Ideas

Open Innovation Contestants Build AI-Based Cancer Tool

Radiation therapy can be lifesaving for lung cancer patients. The first step, though, is having a trained, skilled oncologist who knows how to best segment or mark off the tumor for radiation. This expertise... View Details
Keywords: by Martha Lagace; Health; Medical Devices & Supplies
  • 06 Aug 2014
  • Research & Ideas

Climbing Down from the Ivory Tower

could have been prevented if parents and local health care workers had been involved in designing a solution. Indeed, oral rehydration therapy was successful in countries like Bangladesh, where cooperation... View Details
Keywords: by Carmen Nobel; Education; Health
  • 16 Aug 2004
  • Research & Ideas

Luxury Isn’t What It Used to Be

entrepreneurial ventures. It's a field in constant change, which often creates significant opportunity." The Evergreen Challenge Heritage and prestige are the hallmarks of many luxury brands, some of which are hundreds of years old.... View Details
Keywords: by Julia Hanna; Consumer Products
  • 01 Sep 2015
  • First Look

First Look -- September 1, 2015

comparing the value of care delivery and therefore the cost of therapies. Measuring the value of advanced technologies like proton beam therapy versus intensity-modulated radiation View Details
Keywords: Sean Silverthorne
  • 12 Mar 2019
  • First Look

New Research and Ideas, March 12, 2019

approach to estimate direct costs involved in monitoring and management of anticoagulation therapy for outpatients in an academic primary care clinic setting, post-initiation of therapy. Methods: Time-Driven... View Details
Keywords: Dina Gerdeman
  • 22 Sep 2009
  • First Look

First Look: September 22

and conclude with a discussion of its role in strengthening institutional theory as well as, more broadly, the field of organization studies. Purchase the article ($15): http://www.informaworld.com/smpp/content~db=all~content=a913246271... View Details
Keywords: Martha Lagace
  • 07 Nov 2017
  • First Look

New Research and Ideas: November 7, 2017

implementing a fleet management system in the construction industry. Fleet management would involve a shift from selling power tools to leasing them as a service. For Hilti, it represented an entirely new business model, which would... View Details
Keywords: Carmen Nobel
  • 11 Sep 2012
  • First Look

First Look: September 11

http://hbr.org/product/indispensable-when-leaders-really-matter/an/11129-HBK-ENG Unconscious Thought Reduces Intrusion Development: A Replication and Extension Authors:Julie Krans, Dorte Janecko, and Maarten W. Bos Publication:Journal of Behavior View Details
Keywords: Sean Silverthorne
  • 04 Feb 2014
  • First Look

First Look: February 4

enough. Fisher had an opportunity; his successor had a crisis. What can leaders do before the depth and scope of their companies' crises come into focus? How can they initiate major transformations proactively? As researchers and managers who have been View Details
Keywords: Sean Silverthlorne
  • 10 Oct 2007
  • First Look

First Look: First Look: October 10

to customize therapy for individuals. However, adoption of this approach has progressed slowly and unevenly because the trial-and-error treatment model still governs how the health care system develops, regulates, pays for, and delivers... View Details
Keywords: Martha Lagace
  • 22 May 2020
  • In Practice

Post-COVID Health Care: More Screens, Less Red Tape?

Non-physician providers, such as nurse practitioners and medical assistants, have been given greater latitude to practice independently. And those individuals who are actually able to get tested for COVID-19 can do so by driving through a View Details
Keywords: by Danielle Kost
  • 19 Jun 2007
  • First Look

First Look: June 19, 2007

Intrapersonal Conflict Authors:Katherine L. Milkman, Todd Rogers, and Max H. Bazerman Abstract We report on a field study demonstrating systematic differences between how people anticipate preferences and their subsequent preferences. We... View Details
Keywords: Martha Lagace

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