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  • Article

Patterns of Failure after Involved Field Radiation Therapy for Pediatric and Young Adult Hodgkin Lymphoma

By: Minh-Phuong Huynh-Le, Amanda J. Walker, Scott Duke Kominers, Ido Paz-Priel, Moody D. Wharam and Stephanie A. Terezakis
Involved field radiation therapy (IFRT) is integral in curative therapy for Hodgkin lymphoma (HL), although primarily used in patients with intermediate/high‐risk HL. We present failure patterns and clinical outcomes in a cohort of pediatric and young adult patients... View Details
Keywords: Hematology/oncology; Hodgkin Lymphoma; Involved Field Radiation Therapy; Health Disorders; Health Care and Treatment
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  • Article

Use of Crowd Innovation to Develop an Artificial Intelligence-Based Solution for Radiation Therapy Targeting

By: Raymond H. Mak, Michael G. Endres, Jin Hyun Paik, Rinat A. Sergeev, Hugo Aerts, Christopher L. Williams, Karim R. Lakhani and Eva C. Guinan
Importance: Radiation therapy (RT) is a critical cancer treatment, but the existing radiation oncologist work force does not meet growing global demand. One key physician task in RT planning involves tumor segmentation for targeting, which requires substantial... View Details
Keywords: Crowdsourcing; AI Algorithms; Health Care and Treatment; Collaborative Innovation and Invention; AI and Machine Learning
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  • September–October 2020
  • Article

The Past, Present, and (Near) Future of Gene Therapy and Gene Editing

By: Julia Pian, Amitabh Chandra and Ariel Dora Stern
Emerging gene therapy and gene-editing technologies will have a growing impact on patient lives and health-care delivery. We analyzed a decade of data on clinical trials and venture capital investments to understand the likely trajectory of genetically focused... View Details
Keywords: Gene Therapy; Gene Editing; Impact; Health Care and Treatment; Technological Innovation; Health Testing and Trials; Venture Capital; Change
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  • 18 Apr 2019
  • Research & Ideas

Open Innovation Contestants Build AI-Based Cancer Tool

Radiation therapy can be lifesaving for lung cancer patients. The first step, though, is having a trained, skilled oncologist who knows how to best segment or mark off the tumor for radiation. This expertise... View Details
Keywords: by Martha Lagace; Health; Medical Devices & Supplies
  • 06 Aug 2014
  • Research & Ideas

Climbing Down from the Ivory Tower

could have been prevented if parents and local health care workers had been involved in designing a solution. Indeed, oral rehydration therapy was successful in countries like Bangladesh, where cooperation... View Details
Keywords: by Carmen Nobel; Education; Health
  • Web

Faculty & Advisors | MBA

has been involved with a number of Biologics, cell therapy and telehealth startups. Over her career, she has helped launch 15 products, in medical devices, therapeutics, and diagnostics. She has also... View Details
  • 01 Dec 2023
  • News

Wide Horizon

Comparatively, the ASD field is like the Wild West, he notes: fractured and siloed, with parents involved in disconnected efforts. “Trying to engage families in high-quality research—like we are trying to do... View Details
Keywords: Dan Morrell; Photos by Sarah Wilson
  • Web

Systems Integration - Institute For Strategy And Competitiveness

concentration of volume by medical condition to fewer locations. Numerous studies have shown that technically difficult procedures, such as surgery, radiation therapy, and chemotherapy administration, have been associated with higher... View Details
  • Web

Profiles - MBA

experience across a range of sectors from finance to government and furthering my education across a variety of fields from statistics to economics. These tools, and the support of the Technology Innovation Fellows Program, will empower... View Details
  • 16 Aug 2004
  • Research & Ideas

Luxury Isn’t What It Used to Be

entrepreneurial ventures. It's a field in constant change, which often creates significant opportunity." The Evergreen Challenge Heritage and prestige are the hallmarks of many luxury brands, some of which are hundreds of years old.... View Details
Keywords: by Julia Hanna; Consumer Products
  • 06 Dec 2021
  • News

Vision: Sound Science

meaningful work that I enjoy,” says Simons. “Hearing loss is one of the greatest unmet challenges in medicine. It’s an amazing privilege to be involved in this field at a time when advances by Akouos and... View Details
Keywords: Deb Blagg
  • 01 Sep 2008
  • News

Mara Aspinall

1,500-person division is a leader in the emerging field of personalized medicine, which treats cancer and other diseases with customized therapies that take into account the patient’s specific genetic... View Details
Keywords: Deborah Blagg; Ambulatory Health Care Services; Health, Social Assistance
  • 01 Sep 2015
  • First Look

First Look -- September 1, 2015

comparing the value of care delivery and therefore the cost of therapies. Measuring the value of advanced technologies like proton beam therapy versus intensity-modulated radiation View Details
Keywords: Sean Silverthorne
  • 01 Oct 2021
  • News

Marking 10-Year Connection with Japanese Earthquake Region

With the help of HBS’s Japan Research Center, Professor Hirotaka Takeuchi hosted a virtual reunion to mark the 10-year anniversary of an annual Immersive Field Course in Japan. A decade ago, a group of 22 MBA students from Japan asked... View Details
  • Web

Asia Pacific - Global Activities 2021

Asia Pacific Asia Pacific Marking Ten-Year Connection with Japanese Earthquake Region Pictured: Professor of Management Practice Hirotaka Takeuchi hosted a virtual gathering in March to mark the 10th anniversary of the Immersive Field... View Details
  • 01 Apr 1999
  • News

A Random Sampling of HBS Graduates in the News

transmitted over phone lines to the firm's Natick, Massachusetts, offices, where experienced cardiac nurses also field voice calls. Most calls are questions about symptoms or the advisability of various lifestyle behaviors. Calls View Details
  • 12 Mar 2019
  • First Look

New Research and Ideas, March 12, 2019

approach to estimate direct costs involved in monitoring and management of anticoagulation therapy for outpatients in an academic primary care clinic setting, post-initiation of therapy. Methods: Time-Driven... View Details
Keywords: Dina Gerdeman
  • Web

Past Projects | Social Enterprise | Harvard Business School

outcomes over cost) for both treatment centers and hopefully be able to make recommendations to the radiation therapy field about how to best maximize value (and thus manage... View Details
  • 01 Jun 2002
  • News

Profile: The Invisible Hand - Robert Massie and God's Green Earth

finances dwindled. Finally, at age 12, after years of physical therapy combined with advances in medication, Massie walked away from his wheelchair and cumbersome leg braces. To this day, however, he must cope with pain and self-inject... View Details
Keywords: Garry Emmons; management; ethics
  • 01 Jun 2004
  • News

Luxe Redux

notes Thuy T. Tranthi (MBA 1993), president of Thomas Pink USA, the London-based shirtmaker. “Many of the established brands started out as small, entrepreneurial ventures. It’s a field in constant change, which often creates significant... View Details
Keywords: Julia Hanna; luxury; Retail Trade