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- 2024
- Working Paper
Chimeric Antigen Receptor T-Cell Therapy—Living Drugs: Case Histories of Transformational Advances
By: Amar Bhidé and Srikant M. Datar
In 2017, the US Food and Drug Administration (FDA) approved an immunotherapeutic treatment, called CAR-T therapy, for two kinds of blood cancers—acute leukemia (ALL) and a lymphoma. We describe 1) how CAR-T works, 2) the foundational advances and discoveries, 3) the... View Details
Keywords: Immunotherapy; Health Care and Treatment; Innovation and Invention; Research and Development; Governing Rules, Regulations, and Reforms
Bhidé, Amar, and Srikant M. Datar. "Chimeric Antigen Receptor T-Cell Therapy—Living Drugs: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 21-035, August 2020. (Revised May 2024.)
- 28 Nov 2016
- News
One Obstacle to Curing Cancer: Patient Data Isn’t Shared
- Web
Faculty & Advisors | MBA
immunotherapy strategy which ultimately guided Celgene into the rapidly developing field of immuno-oncology (IO). Kareem started his career at Vertex Pharmaceuticals in formulation development. Mark Robinson MBA ‘93, Harvard University;... View Details
- 22 Feb 2024
- News
Combat-Tested Cancer Coaching
think I'll just rest on my laurels and see what happens now. I was equally as tenacious about finding the next immunotherapy drug that might come out. And so I think that balance was out of whack. I was so focused on that urgency. On the... View Details
- Web
Profiles - MBA
operators to overcome scientific and strategic challenges and break the boundaries of medicine. Moreover, I conduct research on improving immunotherapies for solid tumors in the translational Mitrogotri Lab at Harvard SEAS, and co-founded... View Details
- Web
Kraft Accelerator
in Precision Medicine in Immunotherapy (video) Close DOWNLOAD ALL TOOLS Discover how others in the community are provoking positive change Learn from Leaders Before you download the tool Please complete the form: Your First Name * Your... View Details
- 15 Jan 2018
- Research & Ideas
A Better Business Model for Fighting Cancer
therapies has become a reality, as have immunotherapies that induce or suppress a body’s immune response to treat disease. Yet, this relatively swift progress has not been fast enough for millions of other patients who still lack... View Details