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- December 2012
- Teaching Note
Gene Patents (A) (TN)
By: Richard G. Hamermesh and Matthew Preble
This is the teaching note for case Gene Patents (A). In March 2010, U.S. District Court Judge Robert Sweet overturned 30 years of legal precedent and ruled that unaltered human genes could not be patented. This case reviews patent law and how it relates to our... View Details
- January 2014 (Revised December 2014)
- Case
GenapSys: Business Models for the Genome
By: Richard G. Hamermesh, Joseph B. Fuller and Matthew Preble
GenapSys, a California-based startup, was soon to release a new DNA sequencer that the company's founder, Hesaam Esfandyarpour, believed was truly revolutionary. The sequencer would be substantially less expensive—potentially costing just a few thousand dollars—and... View Details
Keywords: DNA Sequencing; Life Sciences; Business Model; Innovation & Entrepreneurship; Health Care and Treatment; Genetics; Business Strategy; Biotechnology Industry; Pharmaceutical Industry; Technology Industry; Health Industry; Medical Devices and Supplies Industry; United States
Hamermesh, Richard G., Joseph B. Fuller, and Matthew Preble. "GenapSys: Business Models for the Genome." Harvard Business School Case 814-050, January 2014. (Revised December 2014.)
- February 2014
- Case
BGI: Data-driven Research
By: Willy Shih and Sen Chai
BGI has the largest installed gene-sequencing capacity in the world, and to Zhang Gengyun, general manager of the Life Sciences Division, this represented an opportunity to apply his training as a plant breeder and his early career work as a biochemist to improving... View Details
Keywords: Genomics; Gene Sequencing; Life Sciences; Plant Breeding; Human Genome Program; Beijing Genomics Institute; BGI; Rice Genome; Technological Innovation; Innovation Strategy; Research; Research and Development; Science; Genetics; Science-Based Business; Strategy; Commercialization; Corporate Strategy; Information Technology; Applications and Software; Agriculture and Agribusiness Industry; Biotechnology Industry; Food and Beverage Industry; China; United States
Shih, Willy, and Sen Chai. "BGI: Data-driven Research." Harvard Business School Case 614-056, February 2014.
- March 2008 (Revised June 2008)
- Case
The Broad Institute: Applying the Power of Genomics to Medicine
By: Vicki L. Sato and Rachel Gordon
In June 2003, Harvard University and MIT announced an unprecedented partnership to create a biomedical institute, The Broad Institute. The culture of the Broad centered on science, and those involved considered it to be at the edge of the scientific frontier. In just... View Details
Keywords: Education; Health Care and Treatment; Innovation Leadership; Growth and Development Strategy; Organizational Culture; Partners and Partnerships; Research and Development; Genetics
Sato, Vicki L., and Rachel Gordon. "The Broad Institute: Applying the Power of Genomics to Medicine." Harvard Business School Case 608-114, March 2008. (Revised June 2008.)
- 28 Feb 2011
- News
Rebooting the Human Condition
engineered cells, biological tissue, and robots. This perfect storm of innovation will allow humans to shape their own evolution (as well as that of other species) and create solutions to energy, health, and economic problems. Enriquez... View Details
- 2003
- Case
Corning Microarray Technologies
By: Vijay Govindarajan, Chris Trimble and Gautam Bellur
In mid-2000, the scientific community reached a momentous milestone—the complete mapping of the human genome. Researchers in the field of genomics were anxious to dig into a tremendous array of newly possible scientific inquiries, and needed efficient experimental... View Details
- Article
Beyond Magic Bullets: True Innovation in Health Care
By: Vaibhav A. Narayan, Marco Mohwinckel, Gary Pisano, Michael Yang and Husseini Manji
The molecular medicine revolution—based on advances in fields such as genomics and network modeling in the decade since the human genome sequence was completed—has changed the way we think about, study, and approach the development of novel therapies. However, these... View Details
Keywords: Integration; Business Model; Organizational Structure; Health Care and Treatment; Innovation and Invention; Pharmaceutical Industry
Narayan, Vaibhav A., Marco Mohwinckel, Gary Pisano, Michael Yang, and Husseini Manji. "Beyond Magic Bullets: True Innovation in Health Care." Nature Reviews: Drug Discovery 12, no. 2 (February 2013): 85–86.
- October 2011
- Case
Gene Sequencing: Staking a Position in an Expanding Industry
By: Richard G. Hamermesh, Mara Aspinall and Phillip Andrews
Towards the end of 2010, companies in the gene sequencing industry were pushing aggressive R&D programs to develop technologies and products in the race to sequence the entire human genome at a cost of $1,000. It remained to be seen when the "$1,000 genome" would... View Details
Keywords: Genetics; Business Growth and Maturation; Business Plan; Competition; Venture Capital; Biotechnology Industry
Hamermesh, Richard G., Mara Aspinall, and Phillip Andrews. "Gene Sequencing: Staking a Position in an Expanding Industry." Harvard Business School Case 812-004, October 2011.
- 29 May 2001
- Research & Ideas
Genomics: Can We Start Making Money Now?
Now that scientists have mapped the human gene, can drug makers map a road to unlimited riches? For John Lechleiter, Executive Vice President of Eli Lilly and Company's Pharmaceutical Products and Corporate Development, there remain more... View Details
Keywords: by Sean Silverthorne
- Web
Faculty & Advisors | MBA
venture investor. She is the Founder and Managing Director of Arkitekt Ventures, an early stage Health + Bio investment firm with the mission to improve and advance human health. Recognized by the Wall Street Journal as one of the Top Ten... View Details
- Web
Profiles - MBA
an authentic desire to build the world they want to live in. ” Tech areas of interest: AI/ML, Design, Human Computer Interaction, Sustainability, Privacy, Security & Trust Formative experience at the intersection of technology and... View Details
- Web
Advisory Board - Entrepreneurship
investments in over fifty companies, primarily in the biotechnology and communications equipment areas, including Human Genome Sciences, Millennium Pharmaceuticals, Vertex Pharmaceuticals, Appex, Brooktrout... View Details
- 01 Mar 2024
- News
On the Radar
Illustration by Brian Stauffer Illustration by Brian Stauffer Our planet is teeming with trillions of viruses and bacteria, most of which are innocuous or even helpful, but some pose a significant risk to public health, animals, and crops. In recent decades,... View Details
- Web
Recruiting Partners - Health Care
PictureRx Piramal Enterprises Limited Portaero, Inc. Precision Effect PTC Therapeutics Q Quest Diagnostics Inc. R Repligen Corporation Replikins LLC Respironics Roche Diagnostics S Seed Global Health Shire Human Genetic Therapies... View Details
- Web
Dean Nitin Nohria | About
serve as the gateway and gathering hub for the more than 10,000 executives who attend Executive Education courses on campus each year. November 2015 Kraft Precision Medicine Accelerator The Robert and Myra Kraft Family Foundation pledged $20 million to advance the use... View Details
- 01 Feb 2002
- News
As the Future Catches You
Life Science Project at HBS, believes that the future will be defined by the genomic revolution and that world history today is at a fundamental turning point. Combined with advances and developments in other fields, the View Details
- 01 Jun 2000
- News
Managing the Map
Health (NIH) undertook the Human Genome Project, an effort to map the extraordinarily intricate chemical composition of the human genome. Scientists have long believed that... View Details
Keywords: Peter K. Jacobs
- 20 Jul 2017
- News
Life Lab Nurtures Early Stage Startup Day Zero Diagnostics
rise. It’s one of the greatest threats that human health is facing today,” says Miriam Huntley, a DZD cofounder who focuses on computational approaches to genomic analysis. “Patients with severe infections... View Details
- 04 Sep 2019
- News
Advancing Diagnostics that Can Save Lives
tools, expediting the time frame and accuracy of results. Using genomics and machine learning, Day Zero Diagnostics (DZD) and Aikili Biosystems aim to save lives. “A common reaction to our venture is that it is ‘ambitious.’ Clearly our... View Details
Keywords: Susan Young
- 01 Mar 2012
- News
How to Close the Health Gap
companies largely ignored the world’s poor: few new drugs were created to combat tropical diseases and TB. The needs of the developing world also were neglected by the Human Genome Project, one of the great... View Details