Gene Editing - Publications - Faculty & Research - Harvard Business School

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September–October 2020
Article

The Past, Present, and (Near) Future of Gene Therapy and Gene Editing

By: Julia Pian, Amitabh Chandra and Ariel Dora Stern

Emerging gene therapy and gene-editing technologies will have a growing impact on patient lives and health-care delivery. We analyzed a decade of data on clinical trials and venture capital investments to understand the likely trajectory of genetically focused... View Details

Keywords: Gene Therapy; Gene Editing; Impact; Health Care and Treatment; Technological Innovation; Health Testing and Trials; Venture Capital; Change

Find at Harvard

09 Jan 2019
News

Perspectives on gene editing

January 2024 (Revised April 2024)
Case

Target Malaria: Editing Mosquitoes through Gene Drives

By: Shikhar Ghosh and Shweta Bagai

Target Malaria, a non-profit research consortium, is exploring the application of CRISPR-Cas9 gene editing technology to combat malaria in Sub-Saharan Africa. Its approach uses gene drives, a revolutionary tool, to suppress the population of malaria-carrying... View Details

Keywords: Health Disorders; Technological Innovation; Nonprofit Organizations; Business Strategy; Genetics; Ethics; Governing Rules, Regulations, and Reforms; United States; United Kingdom; Burkina Faso; Africa

December 2021
Case

Pairwise

By: José B. Alvarez and Annelena Lobb

Pairwise discusses the strategic approach of a company aiming to “snackify” fruits and vegetables by using CRISPR-Cas9 gene editing to create nutritious, bite-sized foods that could compete with packaged snacks. The company is confronting a number of challenges,... View Details

Keywords: Gene Editing; GMO; Food; Nutrition; Competition; Market Entry and Exit; Public Opinion; Competitive Strategy; Consumer Behavior; Food and Beverage Industry

June 2023
Case

Verve Therapeutics: Taking DNA Editing to Heart

By: Shikhar Ghosh and Shweta Bagai

Verve Therapeutics, a public biotech company based in Boston, created a novel approach to addressing cardiovascular disease (CVD) - a leading cause of deaths globally. The company's approach was a single shot treatment to permanently lower cholesterol, thus reducing... View Details

Keywords: AI; Genetic Engineering; Medicine; Health Care and Treatment; Genetics; Innovation Strategy; Business and Stakeholder Relations; Medical Specialties; Innovation and Invention; Entrepreneurship; Biotechnology Industry

20 Jun 2019
News

What Tech Pioneers Can Learn From Emerging Markets

October 2016 (Revised September 2017)
Case

The CRISPR-Cas9 Quarrel

By: Richard G. Hamermesh and Matthew G. Preble

In mid-2016, the Broad Institute and the University of California, Berkeley were in the middle of a contentious patent dispute over which entity controlled a breakthrough gene editing technology called CRISPR-Cas9. With CRISPR-Cas9, scientists might soon be able to... View Details

Keywords: CRISPR; Broad Institute; University Of California Berkeley; Intellectual Property; Patents; Law; Lawsuits and Litigation; Science; Genetics; Entrepreneurship; Biotechnology Industry; United States

Web

Blavatnik Fellowship in Life Science Entrepreneurship - Health Care

CEO of KiraGen Bio, a biotech company that utilizes machine learning-driven multiplex gene editing to engineer CAR-T cells that can resist the immunosuppressive effects of solid tumor microenvironments. With... View Details

01 Dec 2022
News

My First Job

Edited by Jen McFarland Flint; illustrations by Ross MacDonald Here’s the humbling truth: no matter how high your career soars, how many awards you win or companies you sell or differences you make in this world, everyone has to start... View Details

Keywords: Business Schools & Computer & Management Training; Educational Services

20 May 2022
Blog Post

Nucleate Eco: Connecting Aspiring MBA Entrepreneurs with Cutting Edge Climate Research

national and looks to expand to even more US cities next year. Our founding goal was to help take university research out of the lab and help form startups around it to tackle real-world problems in sustainability. Our teams are focused on a huge diversity of fields... View Details

20 Oct 2003
Research & Ideas

Gaps in the Historical Record: Development of the Electronics Industry

In a recently published book on current international research in business history, edited by Harvard Business School professor Geoffrey Jones, HBS professor emeritus Alfred D. Chandler Jr. contributed an essay on the opportunities... View Details

Keywords: by Alfred D. Chandler Jr.; Consumer Products

01 Jun 2015
News

The Military and the MBA

Edited by April White A US military convoy was halted on a road north of Fallujah, among the most dangerous cities in Iraq. There was a possible IED in its path. They needed orders: Should they reroute? At the same moment, another Marine... View Details

Keywords: Business Schools & Computer & Management Training; Educational Services; National Security and International Affairs; Government

10 Oct 2024
Blog Post

High-Tech Greenhouse Innovations in The Netherlands

by deploying controlled bee houses to facilitate pollination. Other applications for technology and sustainability. Syngenta envisions AI providing new possibilities in agricultural gene editing over the... View Details

01 Mar 2019
News

The Blue-Green Revolution

algae Nannochloropsis gaditana and uncovered a group of genes responsible for regulating oil production. By tweaking one of those genes with the powerful editing tool known as... View Details

Keywords: Alexander Gelfand; illustration by Eric Nyquist

22 Nov 2016
First Look

November 22, 2016

and the University of California, Berkeley were in the middle of a contentious patent dispute over which entity controlled a breakthrough gene editing technology called CRISPR-Cas9. With CRISPR-Cas9,... View Details

Keywords: Sean Silverthorne

18 Jul 2024
Blog Post

Harvard Business School Announces Its 2024-2025 Blavatnik Fellows

and CEO of KiraGen Bio, a biotech company that utilizes machine learning-driven multiplex gene editing to engineer CAR-T cells that can resist the immunosuppressive effects of solid tumor microenvironments.... View Details

10 May 2017
Research & Ideas

Amazon Web Services Changed the Way VCs Fund Startups

hopes to address this question in future research. On the bright side, he says, technological innovations have come so quickly in recent years that there are few industry sectors that have not seen their development costs dramatically decrease. For example, CRISPR... View Details

Keywords: by Michael Blanding; Banking; Financial Services; Information Technology

Web

Rock 100: The Summit - Entrepreneurship

Reasonable People 2nd Edition , Richard Shell Compilation of posts on business development , Tom Eisenmann Getting to Yes: Negotiating Agreement Without Giving In , Roger Fisher, William Ury, Bruce Patton The Founder's Dilemmas:... View Details

Web

3 Technologies that Will Change the World - Course Catalog

company that is redefining digital art and creating a way for artists to capture value from their art. Synthetic Biology – Enabling us to reprogram DNA and rewrite the code of life (25% of sessions): We examine the potential for gene... View Details

14 Jul 2009
First Look

First Look: July 14

Backlash Against Investment Arbitration, edited by Michael Waibel, Asha Kaushal, Kyo-Hwa Chung, and Claire Balchin. London: Wolters Kluwer Law & Business, forthcoming Abstract There are at least three reasons for the current backlash... View Details

Keywords: Martha Lagace

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