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- September–October 2020
- Article
The Past, Present, and (Near) Future of Gene Therapy and Gene Editing
By: Julia Pian, Amitabh Chandra and Ariel Dora Stern
Emerging gene therapy and gene-editing technologies will have a growing impact on patient lives and health-care delivery. We analyzed a decade of data on clinical trials and venture capital investments to understand the likely trajectory of genetically focused... View Details
Keywords: Gene Therapy; Gene Editing; Impact; Health Care and Treatment; Technological Innovation; Health Testing and Trials; Venture Capital; Change
Pian, Julia, Amitabh Chandra, and Ariel Dora Stern. "The Past, Present, and (Near) Future of Gene Therapy and Gene Editing." NEJM Catalyst Innovations in Care Delivery 1, no. 5 (September–October 2020).
- 09 Jan 2019
- News
Perspectives on gene editing
- January 2024 (Revised April 2024)
- Case
Target Malaria: Editing Mosquitoes through Gene Drives
By: Shikhar Ghosh and Shweta Bagai
Target Malaria, a non-profit research consortium, is exploring the application of CRISPR-Cas9 gene editing technology to combat malaria in Sub-Saharan Africa. Its approach uses gene drives, a revolutionary tool, to suppress the population of malaria-carrying... View Details
Keywords: Health Disorders; Technological Innovation; Nonprofit Organizations; Business Strategy; Genetics; Ethics; Governing Rules, Regulations, and Reforms; United States; United Kingdom; Burkina Faso; Africa
Ghosh, Shikhar, and Shweta Bagai. "Target Malaria: Editing Mosquitoes through Gene Drives." Harvard Business School Case 824-068, January 2024. (Revised April 2024.)
- December 2021
- Case
Pairwise
By: José B. Alvarez and Annelena Lobb
Pairwise discusses the strategic approach of a company aiming to “snackify” fruits and vegetables by using CRISPR-Cas9 gene editing to create nutritious, bite-sized foods that could compete with packaged snacks. The company is confronting a number of challenges,... View Details
Keywords: Gene Editing; GMO; Food; Nutrition; Competition; Market Entry and Exit; Public Opinion; Competitive Strategy; Consumer Behavior; Food and Beverage Industry
Alvarez, José B., and Annelena Lobb. "Pairwise." Harvard Business School Case 522-058, December 2021.
- June 2023
- Case
Verve Therapeutics: Taking DNA Editing to Heart
By: Shikhar Ghosh and Shweta Bagai
Verve Therapeutics, a public biotech company based in Boston, created a novel approach to addressing cardiovascular disease (CVD) - a leading cause of deaths globally. The company's approach was a single shot treatment to permanently lower cholesterol, thus reducing... View Details
Keywords: AI; Genetic Engineering; Medicine; Health Care and Treatment; Genetics; Innovation Strategy; Business and Stakeholder Relations; Medical Specialties; Innovation and Invention; Entrepreneurship; Biotechnology Industry
Ghosh, Shikhar, and Shweta Bagai. "Verve Therapeutics: Taking DNA Editing to Heart." Harvard Business School Case 823-113, June 2023.
- 20 Jun 2019
- News
What Tech Pioneers Can Learn From Emerging Markets
- October 2016 (Revised September 2017)
- Case
The CRISPR-Cas9 Quarrel
By: Richard G. Hamermesh and Matthew G. Preble
In mid-2016, the Broad Institute and the University of California, Berkeley were in the middle of a contentious patent dispute over which entity controlled a breakthrough gene editing technology called CRISPR-Cas9. With CRISPR-Cas9, scientists might soon be able to... View Details
Keywords: CRISPR; Broad Institute; University Of California Berkeley; Intellectual Property; Patents; Law; Lawsuits and Litigation; Science; Genetics; Entrepreneurship; Biotechnology Industry; United States
Hamermesh, Richard G., and Matthew G. Preble. "The CRISPR-Cas9 Quarrel." Harvard Business School Case 817-020, October 2016. (Revised September 2017.)
- Web
Blavatnik Fellowship in Life Science Entrepreneurship - Health Care
CEO of KiraGen Bio, a biotech company that utilizes machine learning-driven multiplex gene editing to engineer CAR-T cells that can resist the immunosuppressive effects of solid tumor microenvironments. With... View Details
- 01 Dec 2022
- News
My First Job
Edited by Jen McFarland Flint; illustrations by Ross MacDonald Here’s the humbling truth: no matter how high your career soars, how many awards you win or companies you sell or differences you make in this world, everyone has to start... View Details
- 20 May 2022
- Blog Post
Nucleate Eco: Connecting Aspiring MBA Entrepreneurs with Cutting Edge Climate Research
national and looks to expand to even more US cities next year. Our founding goal was to help take university research out of the lab and help form startups around it to tackle real-world problems in sustainability. Our teams are focused on a huge diversity of fields... View Details
- 20 Oct 2003
- Research & Ideas
Gaps in the Historical Record: Development of the Electronics Industry
In a recently published book on current international research in business history, edited by Harvard Business School professor Geoffrey Jones, HBS professor emeritus Alfred D. Chandler Jr. contributed an essay on the opportunities... View Details
- 01 Jun 2015
- News
The Military and the MBA
Edited by April White A US military convoy was halted on a road north of Fallujah, among the most dangerous cities in Iraq. There was a possible IED in its path. They needed orders: Should they reroute? At the same moment, another Marine... View Details
- Web
High-Tech Greenhouse Innovations in The Netherlands - Blog - Business & Environment
Blog Blog Filter Results Arrow Down Arrow Up Read posts from Author Alumni Author HBS Faculty Author HBS Staff Author Students Topics Topics Accelerating Climate Solutions Conference 2023 Alumni Alumni Programs Alumni in Climate Networking Series Business & Environment... View Details
- 01 Mar 2019
- News
The Blue-Green Revolution
algae Nannochloropsis gaditana and uncovered a group of genes responsible for regulating oil production. By tweaking one of those genes with the powerful editing tool known as... View Details
- 18 Jul 2024
- Blog Post
Harvard Business School Announces Its 2024-2025 Blavatnik Fellows
and CEO of KiraGen Bio, a biotech company that utilizes machine learning-driven multiplex gene editing to engineer CAR-T cells that can resist the immunosuppressive effects of solid tumor microenvironments.... View Details
- 22 Nov 2016
- First Look
November 22, 2016
and the University of California, Berkeley were in the middle of a contentious patent dispute over which entity controlled a breakthrough gene editing technology called CRISPR-Cas9. With CRISPR-Cas9,... View Details
Keywords: Sean Silverthorne
- Web
Rock 100: The Summit - Entrepreneurship
Reasonable People 2nd Edition , Richard Shell Compilation of posts on business development , Tom Eisenmann Getting to Yes: Negotiating Agreement Without Giving In , Roger Fisher, William Ury, Bruce Patton The Founder's Dilemmas:... View Details
- 14 Jul 2009
- First Look
First Look: July 14
Backlash Against Investment Arbitration, edited by Michael Waibel, Asha Kaushal, Kyo-Hwa Chung, and Claire Balchin. London: Wolters Kluwer Law & Business, forthcoming Abstract There are at least three reasons for the current backlash... View Details
Keywords: Martha Lagace
- 10 May 2017
- Research & Ideas
Amazon Web Services Changed the Way VCs Fund Startups
hopes to address this question in future research. On the bright side, he says, technological innovations have come so quickly in recent years that there are few industry sectors that have not seen their development costs dramatically decrease. For example, CRISPR... View Details
- 30 Mar 2010
- First Look
First Look: March 30
Read the preview: http://hbr.org/2010/04/fixing-health-care-on-the-front-lines/ar/1 Happiness Adaptation to Income beyond "Basic Needs" Authors:Rafael Di Tella and Robert MacCulloch Publication:Chap. 8 in International Differences in Well-Being, View Details
Keywords: Sean Silverthorne