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  • November 2005 (Revised November 2005)
  • Case

Massachusetts General Hospital and the Enbrel Royalty

By: David S. Scharfstein and Darren R. Smart
Massachusetts General Hospital is considering selling its royalty interest in Enbrel, Amgen's blockbuster drug for the treatment of rheumatoid arthritis. In assessing whether to sell, and at what price, the hospital must determine its value to a potential buyer as well... View Details
Keywords: Valuation; Price; Investment Return; Capital; Value; Revenue; Health Care and Treatment; Health Industry; Health Industry; Massachusetts
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Scharfstein, David S., and Darren R. Smart. "Massachusetts General Hospital and the Enbrel Royalty." Harvard Business School Case 206-075, November 2005. (Revised November 2005.)
  • November 2009 (Revised January 2011)
  • Case

International AIDS Vaccine Initiative

By: Allen S. Grossman and Cathy Ross
Dedicated to accelerating the development of a safe, effective, accessible, preventive HIV vaccine, the International AIDS Vaccine Initiative (IAVI) pioneered ways of addressing the inadequate incentive structures that prevented progress toward vaccines for AIDS and... View Details
Keywords: Developing Countries and Economies; Globalized Firms and Management; Health Care and Treatment; Health Disorders; Business and Government Relations; Partners and Partnerships; Research and Development; Social Enterprise; Health Industry
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Grossman, Allen S., and Cathy Ross. "International AIDS Vaccine Initiative." Harvard Business School Case 310-015, November 2009. (Revised January 2011.)
  • 2021
  • Other Unpublished Work

As Healthcare Costs Escalate, A New George and Regi Herzlinger Industry Award Shines a Spotlight on Innovation Education

By: Regina E. Herzlinger
The winners of the first ever CAHME/George and Regi Herzlinger Innovation Education Award have just been announced. Regi Herzlinger explains why rewarding, supporting, and encouraging innovation education is so critical to solving the challenges of our industry. View Details
Keywords: Health Care and Treatment; Management; Innovation and Invention; Education
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"As Healthcare Costs Escalate, A New George and Regi Herzlinger Industry Award Shines a Spotlight on Innovation Education." Commission on Accreditation of Healthcare Management Education (CAHME), March 2021.
  • Article

A Collective Biological Processing Algorithm for EKG Signals

By: Mike Horia Teodorescu
We establish and explore an analogy between hunting by packs of agents and signal processing. We present a version of adaptive ‘Hunting Swarm’ algorithm (HSA), apply it to EKG signals, and investigate the influence of the model parameters on the filtering of stationary... View Details
Keywords: Artificial Intelligence; Technological Innovation; Health Care and Treatment
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Teodorescu, Mike Horia. "A Collective Biological Processing Algorithm for EKG Signals." Proceedings of the International Conference on Bio-inspired Systems and Signal Processing 4th (2011): 413–420. (IEEE BIOSIGNALS 2011.)
  • Global Healthcare 2002
  • Article

Disruptive Innovation -- New Diagnosis and Treatment for the Systemic Maladies of Healthcare

By: John W. Kenagy and Clayton M. Christensen
Keywords: Disruption; Innovation and Invention; Health Care and Treatment
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Kenagy, John W., and Clayton M. Christensen. "Disruptive Innovation -- New Diagnosis and Treatment for the Systemic Maladies of Healthcare." World Markets Series, Business Briefing (Global Healthcare 2002): 14–17.
  • 10 Oct 2000
  • Research & Ideas

Cross-Sector Collaboration: Lessons from the International Trachoma Initiative

The aim, write the authors, is "to deepen our understanding of the process of cross-sector collaboration in the public health arena and the factors contributing to effective partnering." They begin with brief descriptions of... View Details
Keywords: by Diana Barrett, James Austin & Sheila McCarthy
  • April 1989 (Revised May 1993)
  • Case

Novel Combination of Two Drugs (A)

By: Regina E. Herzlinger
Keywords: Health; Health Care and Treatment; Pharmaceutical Industry
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Herzlinger, Regina E. "Novel Combination of Two Drugs (A)." Harvard Business School Case 189-168, April 1989. (Revised May 1993.)
  • February 2022
  • Case

Leading The UK Vaccine Task Force

By: Amy C. Edmondson and Claudia Pienica
This case describes the first six months of the UK Vaccine Taskforce, under the leadership of Kate Bingham. With a career spent in the private sector as a biotech investor, Bingham’s appointment within the government was considered unusual. The overarching brief given... View Details
Keywords: COVID-19; Vaccine; Government; Health Pandemics; Health Care and Treatment; Science; Innovation and Invention; Groups and Teams; Leadership; Decision Making; Government and Politics; Health; Innovation and Management; Governance; Change; Government Administration; Health Industry; Health Industry; Health Industry; Europe; United Kingdom
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Edmondson, Amy C., and Claudia Pienica. "Leading The UK Vaccine Task Force." Harvard Business School Case 622-079, February 2022.
  • November 2005 (Revised December 2006)
  • Case

Jeanette Clough at Mount Auburn Hospital

Jeanette Clough, the CEO of Mt. Auburn Hospital, successfully leads a turnaround for the struggling local hospital. When she assumed leadership of Mt. Auburn in 1998, the hospital had recently suffered a $10 million loss. During her first six months, several members of... View Details
Keywords: Organizational Change and Adaptation; Change Management; Leading Change; Expansion; Health Care and Treatment; Business and Community Relations; Health Industry; Cambridge
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Roberts, Laura Morgan, and Ayesha Kanji. "Jeanette Clough at Mount Auburn Hospital." Harvard Business School Case 406-068, November 2005. (Revised December 2006.)
  • November 1980
  • Article

Patient Perspective on the Curative Process: A Comparison of Day Treatment and Outpatient Psychotherapy Groups

By: Timothy Butler and Adelaide Fuhriman
Keywords: Health; Groups and Teams; Health Care and Treatment; Perspective
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Butler, Timothy, and Adelaide Fuhriman. "Patient Perspective on the Curative Process: A Comparison of Day Treatment and Outpatient Psychotherapy Groups." Small Group Behavior 11, no. 4 (November 1980).
  • 19 Jun 2012
  • First Look

First Look: June 19

312-002 McKesson, a large, diversified drug distribution and health care IT company, is considering development of new business offerings to help private practice physicians remain independent. The company,... View Details
Keywords: Sean Silverthorne
  • July 2002 (Revised August 2002)
  • Case

Washington Hospital Center (B): The Power of Insight

By: Rosabeth M. Kanter and Michelle Heskett
Dr. Craig Feied considers how to take a major technical innovation beyond his own department into a large hospital system. Reviews how proprietary information systems became indispensable in the department of emergency medicine and what it took to introduce the change... View Details
Keywords: Change Management; Health Care and Treatment; Nonprofit Organizations; Medical Specialties; Organizational Culture; Crisis Management; Technological Innovation; Higher Education; Adoption; Health Industry; District of Columbia
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Kanter, Rosabeth M., and Michelle Heskett. "Washington Hospital Center (B): The Power of Insight." Harvard Business School Case 303-020, July 2002. (Revised August 2002.)
  • August 2013 (Revised October 2013)
  • Case

MedImmune Ventures

By: Richard G. Hamermesh and David Lane
Ron Laufer is the new Senior Managing Director of MedImmune Ventures, the corporate venture capital arm of AstraZeneca, a leading pharmaceuticals firm. Laufer has to decide whether to pursue a high-potential, but very risky, early-stage investment. The decision Laufer... View Details
Keywords: MedImmune; MedImmune Ventures; AstraZeneca; NeuProtect; Corporate Venturing; Biotechnology; Venture Investing; Venture Capital; Health Care and Treatment; Pharmaceutical Industry; Financial Services Industry; Biotechnology Industry; United States; Australia; Europe; London
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Hamermesh, Richard G., and David Lane. "MedImmune Ventures." Harvard Business School Case 814-023, August 2013. (Revised October 2013.)
  • December 2005 (Revised April 2010)
  • Teaching Note

Leerink Swann & Co.: Creating Competitive Advantage (TN)

By: Boris Groysberg and Andrew N. McLean
Keywords: Health Care and Treatment; Capital Markets; Banking Industry
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Groysberg, Boris, and Andrew N. McLean. "Leerink Swann & Co.: Creating Competitive Advantage (TN)." Harvard Business School Teaching Note 406-061, December 2005. (Revised April 2010.)
  • November 2009 (Revised December 2009)
  • Case

GTC Biotherapeutics: Developing Medicines in the Milk of Goats

By: Ray A. Goldberg and Sarah Morton
GTC is the first company in the animal world to receive FDA approval of a transgenic pharmaceutical. What are the implications for other firms in plants and animals and their opportunities to produce new medicines in an economical and safe fashion? View Details
Keywords: Health Care and Treatment; Animal-Based Agribusiness; Plant-Based Agribusiness; Science-Based Business; Medical Specialties; Product; Technological Innovation; Health Industry; Health Industry; United States
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Goldberg, Ray A., and Sarah Morton. "GTC Biotherapeutics: Developing Medicines in the Milk of Goats." Harvard Business School Case 910-403, November 2009. (Revised December 2009.)
  • April 1992 (Revised March 1993)
  • Case

Brigham and Women's Hospital in 1992, The

Brigham and Women's Hospital is a highly successful teaching hospital in 1992. However, the hospital sector is undergoing a major transition and the hospital faces uncertainty about changing demographic trends, new types of competitors, and technological and scientific... View Details
Keywords: Risk and Uncertainty; Change Management; Social Entrepreneurship; Decision Making; Health Care and Treatment; Business Strategy; Health Industry; Health Industry; Massachusetts
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Teisberg, Elizabeth O. "Brigham and Women's Hospital in 1992, The ." Harvard Business School Case 792-095, April 1992. (Revised March 1993.)
  • November 2012
  • Supplement

Amylin Pharmaceuticals (B)

By: Richard G. Hamermesh and Carin-Isabel Knoop
Amylin Pharmaceuticals brought two first-in-class diabetes drugs to market, Byetta and Symlin, in 2005, which were sold in over 80 countries with $650.7 million in sales by 2011. However, the company remained unprofitable as sales plateaued. The small pharmaceutical... View Details
Keywords: Pharmaceuticals; Bristol-Myers Squibb; Health Care and Treatment; Pharmaceutical Industry; United States
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Hamermesh, Richard G., and Carin-Isabel Knoop. "Amylin Pharmaceuticals (B)." Harvard Business School Supplement 813-091, November 2012.
  • Simulation

Going to the Dentist: Futuredontics

By: Gerald Zaltman
Keywords: Health Care and Treatment
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Zaltman, Gerald. "Going to the Dentist: Futuredontics." Simulation and Teaching Note. Multimedia. (Multimedia Producer: Melissa Dailey.)
  • August 2006
  • Teaching Note

Adrian Ivinson at the Harvard Center for Neurodegeneration and Repair (TN)

By: Robert Steven Kaplan
Keywords: Health Care and Treatment
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Kaplan, Robert Steven. "Adrian Ivinson at the Harvard Center for Neurodegeneration and Repair (TN)." Harvard Business School Teaching Note 407-004, August 2006.
  • December 1990
  • Supplement

American Heart Association's Heartguide, Supplement

By: Ray A. Goldberg
Keywords: Health Care and Treatment
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Goldberg, Ray A. "American Heart Association's Heartguide, Supplement." Harvard Business School Supplement 591-057, December 1990.
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