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  • All HBS Web  (719)
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  • September 2020
  • Case

Minerva 2004: Discovery

By: John R. Wells and Benjamin Weinstock
After nearly five years in operation, Doctor Cynthia Bamdad, founder and CEO of Minerva Biotechnologies Corporation (Minerva), was reflecting on the company’s next steps. In a few short years, she and her small team had managed to develop a nanoparticle process for... View Details
Keywords: Entrepreneurship; Financing and Loans; Strategy; Decision Choices and Conditions; Biotechnology Industry
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Wells, John R., and Benjamin Weinstock. "Minerva 2004: Discovery." Harvard Business School Case 721-389, September 2020.
  • July 2024
  • Article

Mass General Brigham’s Patient-Reported Outcomes Measurement System: A Decade of Learnings

By: Jason B. Liu, Robert S. Kaplan, David W. Bates, Mario O. Edelen, Rachel C. Sisodia and Andrea L. Pusic
This article describes the strategies that leaders at the Mass General Brigham (MGB) health system have used in launching a standardized patient-reported outcome measure (PROM) collection program in 2012, a major step in the value-based transformation of health care.... View Details
Keywords: Patient-reported Outcomes; Value Based Health Care; Health Care and Treatment; Transformation; Outcome or Result; Organizational Change and Adaptation; Performance Improvement; Health Industry
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Liu, Jason B., Robert S. Kaplan, David W. Bates, Mario O. Edelen, Rachel C. Sisodia, and Andrea L. Pusic. "Mass General Brigham’s Patient-Reported Outcomes Measurement System: A Decade of Learnings." NEJM Catalyst Innovations in Care Delivery 5, no. 7 (July 2024).
  • 07 Jun 2016
  • First Look

June 7, 2016

discontinuity design that facilitates sharper identification of treatment effects, we find a significant and discontinuous increase in tax avoidance following Russell 2000 inclusion. The tax avoidance involves the use of tax shelters, and... View Details
Keywords: Sean Silverthorne
  • 2023
  • Working Paper

Design-Based Inference for Multi-arm Bandits

By: Dae Woong Ham, Iavor I. Bojinov, Michael Lindon and Martin Tingley
Multi-arm bandits are gaining popularity as they enable real-world sequential decision-making across application areas, including clinical trials, recommender systems, and online decision-making. Consequently, there is an increased desire to use the available... View Details
Keywords: Analytics and Data Science; Mathematical Methods
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Ham, Dae Woong, Iavor I. Bojinov, Michael Lindon, and Martin Tingley. "Design-Based Inference for Multi-arm Bandits." Harvard Business School Working Paper, No. 24-056, March 2024.
  • April 18, 2013
  • Article

Leading Clinicians and Clinicians Leading

By: Richard Bohmer
More effective models of care delivery are needed, but their successful implementation depends on effective care teams and good management of local operations (clinical microsystems). Clinicians influence both, and local clinician leaders will have several key tasks. View Details
Keywords: Health Care; Performance; Leadership; Health Care and Treatment; Health Industry
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Bohmer, Richard. "Leading Clinicians and Clinicians Leading." New England Journal of Medicine 368, no. 16 (April 18, 2013): 1468–1470.
  • 2011
  • Working Paper

The Flexible Substitution Logit: Uncovering Category Expansion and Share Impacts of Marketing Instruments

By: Qiang Liu, Thomas J. Steenburgh and Sachin Gupta
Different instruments are relevant for different marketing objectives (category demand expansion or market share stealing). To help brand managers make informed marketing mix decisions, it is essential that marketing mix models appropriately measure the different... View Details
Keywords: Decision Choices and Conditions; Forecasting and Prediction; Investment; Brands and Branding; Marketing Strategy; Demand and Consumers; Mathematical Methods
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Liu, Qiang, Thomas J. Steenburgh, and Sachin Gupta. "The Flexible Substitution Logit: Uncovering Category Expansion and Share Impacts of Marketing Instruments." Harvard Business School Working Paper, No. 12-012, September 2011.
  • 13 Jan 2015
  • First Look

First Look: January 13

can TV advertising remain an effective means of promoting and selling products and services? In this article, the author draws upon his research to argue that TV advertising remains a powerful vehicle for capturing people's attention,... View Details
Keywords: Sean Silverthorne
  • 2020
  • Working Paper

Targeting for Long-Term Outcomes

By: Jeremy Yang, Dean Eckles, Paramveer Dhillon and Sinan Aral
Decision makers often want to target interventions so as to maximize an outcome that is observed only in the long term. This typically requires delaying decisions until the outcome is observed or relying on simple short-term proxies for the long-term outcome. Here we... View Details
Keywords: Targeted Marketing; Optimization; Churn Management; Marketing; Customer Relationship Management; Policy; Learning; Outcome or Result
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Yang, Jeremy, Dean Eckles, Paramveer Dhillon, and Sinan Aral. "Targeting for Long-Term Outcomes." Working Paper, October 2020.
  • 2023
  • Article

Balancing Risk and Reward: An Automated Phased Release Strategy

By: Yufan Li, Jialiang Mao and Iavor Bojinov
Phased releases are a common strategy in the technology industry for gradually releasing new products or updates through a sequence of A/B tests in which the number of treated units gradually grows until full deployment or deprecation. Performing phased releases in a... View Details
Keywords: Product Launch; Mathematical Methods; Product Development
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Li, Yufan, Jialiang Mao, and Iavor Bojinov. "Balancing Risk and Reward: An Automated Phased Release Strategy." Advances in Neural Information Processing Systems (NeurIPS) (2023).
  • 14 Nov 2017
  • First Look

New Research and Ideas: November 14, 2017

through three examples: the design of medical residency matching programs, a scrip system to allocate food donations to food banks, and the recent "Incentive Auction" that reallocated wireless spectrum from television broadcasters to telecoms. Our lead examples show... View Details
Keywords: Carmen Nobel
  • 2018
  • Working Paper

Show or Tell? Improving Agent Decision Making in a Tanzanian Mobile Money Field Experiment

By: Jason Acimovic, Chris Parker, David F. Drake and Karthik Balasubramanian
When workers make operational decisions, the firm's global knowledge and the workers’ domain-specific knowledge complement each other. Oftentimes workers have the final decision-making power. Two key decisions a firm makes when designing systems to support these... View Details
Keywords: Employees; Decision Making; Training; Performance Improvement; Money; Mobile Technology; Developing Countries and Economies; Financial Services Industry
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Acimovic, Jason, Chris Parker, David F. Drake, and Karthik Balasubramanian. "Show or Tell? Improving Agent Decision Making in a Tanzanian Mobile Money Field Experiment." Harvard Business School Working Paper, No. 18-106, May 2018.
  • October 2005 (Revised October 2008)
  • Case

Virginia Mason Medical Center

By: Richard M.J. Bohmer and Erika Ferlins
In 2000, Dr. Gary Kaplan became CEO of the Virginia Mason Medical Center in Seattle, Washington. The hospital was facing significant challenges: It was losing money for the first time in its history, staff morale had plummeted, and area hospitals presented ardent... View Details
Keywords: Health Care and Treatment; Management Analysis, Tools, and Techniques; Production; Organizational Change and Adaptation; Problems and Challenges; Quality; Competition; Seattle
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Bohmer, Richard M.J., and Erika Ferlins. "Virginia Mason Medical Center." Harvard Business School Case 606-044, October 2005. (Revised October 2008.)
  • Research Summary

Current Research: Issues in Corporate Governance

Effectiveness of shareholder voting
Reform of shareholder voting is a key component of legislation arising from the financial crisis of 2008. Professor Gow examines the effect of shareholder voting on corporate actions, particularly on... View Details
  • Forthcoming
  • Book

Innovating in Healthcare: Creating Breakthrough Tech, Services, Drugs, Products, and Business Models

By: Regina E. Herzlinger
Innovating in Healthcare offers effective approaches for designing, reworking, and implementing innovative healthcare services, products, and business models. It will help anyone working in healthcare service or product development, from hospitals to startups,... View Details
Keywords: Health Care and Treatment; Service Delivery; Product Development; Business Model; Innovation and Invention; Health Industry
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Herzlinger, Regina E. Innovating in Healthcare: Creating Breakthrough Tech, Services, Drugs, Products, and Business Models. Boston, MA: John Wiley & Sons, forthcoming.
  • 19 Mar 2009
  • Working Paper Summaries

Beyond Gender and Negotiation to Gendered Negotiations

Keywords: by Deborah Kolb & Kathleen L. McGinn
  • 2025
  • Working Paper

Tax Planning, Illiquidity, and Credit Risks: Evidence from DeFi Lending

By: Lisa De Simone, Peiyi Jin and Daniel Rabetti
This study establishes a plausible causal link between tax-planning-induced illiquidity and credit risks in lending markets. Exploiting an exogenous tax shock imposed by the Internal Revenue Service (IRS) on cryptocurrency gains, along with millions of transactions in... View Details
Keywords: Cryptocurrency; Taxation; Financial Liquidity; Credit; Financing and Loans; Financial Markets
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De Simone, Lisa, Peiyi Jin, and Daniel Rabetti. "Tax Planning, Illiquidity, and Credit Risks: Evidence from DeFi Lending." Working Paper, February 2025.
  • November 2024
  • Article

Preference Externality Estimators: A Comparison of Border Approaches and IVs

By: Xi Ling, Wesley R. Hartmann and Tomomichi Amano
This paper compares two estimators—the Border Approach and an Instrumental Variable (IV) estimator—using a unified framework where identifying variation arises from “preference externalities,” following the intuition in Waldfogel (2003). We highlight two dimensions in... View Details
Keywords: Econometrics; Casual Inference; Marketing; Economics; Advertising; Mathematical Methods
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Ling, Xi, Wesley R. Hartmann, and Tomomichi Amano. "Preference Externality Estimators: A Comparison of Border Approaches and IVs." Management Science 70, no. 11 (November 2024): 7892–7910.
  • Article

Value of New Performance Information in Healthcare: Evidence from Japan

By: Susanna Gallani, Takehisa Kajiwara and Ranjani Krishnan
Mandatory measurement and disclosure of outcome measures are commonly used policy tools in healthcare. The effectiveness of such disclosures relies on the extent to which the new information produced by the mandatory system is internalized by the healthcare... View Details
Keywords: Value Of Information; Feedback; Patient Satisfaction; Healthcare; Health Care and Treatment; Satisfaction; Information; Measurement and Metrics; Performance Improvement
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Gallani, Susanna, Takehisa Kajiwara, and Ranjani Krishnan. "Value of New Performance Information in Healthcare: Evidence from Japan." International Journal of Health Economics and Management 20, no. 4 (December 2020): 319–357.
  • September 2007
  • Case

Collaborating to Improve

By: Richard M.J. Bohmer and Ingrid M. Nembhard
Madison Memorial Hospital is deciding between a variety of quality improvement strategies. Highlights quality improvement collaborative—organized programs popularized by the Institute for Healthcare Improvement in which teams from multiple institutions work together to... View Details
Keywords: Health Care and Treatment; Service Delivery; Performance Improvement; Quality; Groups and Teams; Cooperation; Integration; Health Industry
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Bohmer, Richard M.J., and Ingrid M. Nembhard. "Collaborating to Improve." Harvard Business School Case 608-054, September 2007.
  • 19 Dec 2023
  • Research & Ideas

$15 Billion in Five Years: What Data Tells Us About MacKenzie Scott’s Philanthropy

$25,000 of annual revenue Private foundations After removing these and a few other special cases for which tax data were not available, we were left with 1,625 organizations. Of these, 1,190 organizations disclosed the size of their gifts. It is too soon to gauge the... View Details
Keywords: by Matthew Lee, Brian Trelstad, and Ethan Tran
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