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  • September 2014
  • Case

Pfizer's Centers for Therapeutic Innovation (CTI)

By: Gary Pisano, James Weber and Kait Szydlowski
In 2010, Pfizer established four small research units in New York, Boston, San Francisco, and San Diego located close to several premier Academic Medical Centers (AMCs), or hospitals with adjoining medical schools. The goal of these units was to redesign collaboration... View Details
Keywords: Drug Development; Academic Collaboration; Research And Development; Innovation; Translational Research; Management; Operations; Problems and Challenges; Research; Science; Information Technology; Strategy; Biotechnology Industry; Pharmaceutical Industry; North and Central America; Europe; Asia
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Pisano, Gary, James Weber, and Kait Szydlowski. "Pfizer's Centers for Therapeutic Innovation (CTI)." Harvard Business School Case 615-024, September 2014.
  • April 2006
  • Background Note

Designing Sustainable Service Models

By: Frances X. Frei
Taught as the second module in a Harvard Business School course on Managing Service Operations. Addresses the challenge of designing service models that effectively incorporate a customer operating role, as well as how to align operations to deliver value to both the... View Details
Keywords: Business Model; Customers; Design; Managerial Roles; Consumer Behavior; Service Operations; Power and Influence; Value
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Frei, Frances X. "Designing Sustainable Service Models." Harvard Business School Background Note 606-031, April 2006.
  • May–June 2021
  • Article

Capturing Value in Platform Business Models that Rely on User-Generated Content

By: Hemang Subramanian, Sabyasachi Mitra and Sam Ransbotham
Business models increasingly depend on inputs from outside traditional organizational boundaries. For example, platforms that generate revenue from advertising, subscription, or referral fees often rely on user-generated content (UGC). But there is considerable... View Details
Keywords: Business Model; Network Effects; Mergers and Acquisitions; Valuation; Risk and Uncertainty
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Subramanian, Hemang, Sabyasachi Mitra, and Sam Ransbotham. "Capturing Value in Platform Business Models that Rely on User-Generated Content." Organization Science 32, no. 3 (May–June 2021): 804–823.
  • 2014
  • Book

Business History

By: Walter A. Friedman and Geoffrey Jones
This volume contains a selection of 42 foundational articles on the discipline of business history written between 1934 and the present day by scholars based in the United States, Europe, Asia, and Latin America. A wide-ranging editorial introduction describes the... View Details
Keywords: Economic History; Business History; History
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Friedman, Walter A. and Geoffrey Jones, eds. Business History. Northampton, MA: Edward Elgar Publishing, 2014.
  • January 2017
  • Supplement

Hello Alfred: Come Home Happy — Operating the Business Model Exercise

By: Joseph B. Fuller and Christopher Payton
On a mission to "automate the on-demand economy," Harvard Business School classmates Marcela Sapone and Jessica Beck launched Hello Alfred in 2013 to provide subscribers with an "Alfred" to complete various chores for a monthly fee. In early 2016, the company has built... View Details
Keywords: Growth and Development Strategy; Internet and the Web; Business Startups; Service Operations; Service Industry; New York (city, NY); Boston
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Fuller, Joseph B., and Christopher Payton. "Hello Alfred: Come Home Happy — Operating the Business Model Exercise." Harvard Business School Spreadsheet Supplement 317-705, January 2017.
  • Article

Organizational Innovation in the Multinational Enterprise: Internalization Theory and Business History

By: Teresa da Silva Lopes, Mark Casson and Geoffrey Jones
This article engages in a methodological experiment by using historical evidence to challenge a common misperception about internalization theory. The theory has often been criticized for maintaining that it assumes a hierarchically organized MNE based on knowledge... View Details
Keywords: Internalization; Multinational Strategy; Business History; Organization And Management Theory; Globalization; Entrepreneurship; Governance; History; Organizations; Theory; Africa; Asia; Europe; Latin America; North and Central America
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da Silva Lopes, Teresa, Mark Casson, and Geoffrey Jones. "Organizational Innovation in the Multinational Enterprise: Internalization Theory and Business History." Journal of International Business Studies 50, no. 8 (October 2019): 1338–1358.
  • January 2022
  • Background Note

Residual Income Valuation Model

By: Charles C.Y. Wang and Albert Shin
This note explains the residual income valuation model (RIM), how it relates to "traditional" valuation models, the intuition behind its use, and empirical research related to its value relevance. RIM is theoretically equivalent to the dividend discount model and the... View Details
Keywords: Residual Income Valuation; Valuation; Research; Theory; Measurement and Metrics; Performance; Financial Management; Business Strategy
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Wang, Charles C.Y., and Albert Shin. "Residual Income Valuation Model." Harvard Business School Background Note 122-070, January 2022.
  • 27 Mar 2015
  • Working Paper Summaries

Capital Requirements, Risk Choice, and Liquidity Provision in a Business Cycle Model

Keywords: by Juliane Begenau; Banking; Financial Services
  • July 2018 (Revised March 2019)
  • Teaching Note

Hilti (A): Fleet Management?

By: Ramon Casadesus-Masanell and Jan Rivkin
This Teaching Note accompanies the case HBS No. 718-419, “Hilti (A): Fleet Management.” It provides guidelines for class discussion, as well as a board plan and transcripts of the associated videos, Hilti Fleet Management Video Supplements.
The associated case... View Details
Keywords: Business Model Innovation; Total Customer Value; Innovation; Inventions; Business Models; Value Chains; Transformations; Focusing On Customers; Business Model; Restructuring; Transformation; Customer Value and Value Chain; Decision Making; Customer Focus and Relationships; Customer Relationship Management; Construction; Innovation and Invention; Leasing; Strategy; Liechtenstein; Switzerland; Europe
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Casadesus-Masanell, Ramon, and Jan Rivkin. "Hilti (A): Fleet Management?" Harvard Business School Teaching Note 719-404, July 2018. (Revised March 2019.)
  • Teaching Interest

Launching New Ventures—Jump-Starting Innovation for Entrepreneurs and Business Owners (Executive Education)

By: William R. Kerr
Starting up a new venture amid rapid change is fraught with challenges. Whether you are starting a new business, launching a new business line, or building an entrepreneurial culture within a small-to-midsize company, this program provides a new perspective and core... View Details
  • 13 Oct 2022
  • Other Presentation

4 Business Ideas That Changed the World: Disruptive Innovation

By: Amy Bernstein, Rita McGrath, Felix Oberholzer-Gee and Derek van Bever
A roundtable conversation takes stock of Clayton Christensen’s influential theory. This first in a series of roundtable conversations assessing the origins and impact of four breakthrough ideas.

In the 1980s, Clayton Christensen cofounded a startup that... View Details
Keywords: Disruptive Innovation
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"4 Business Ideas That Changed the World: Disruptive Innovation." HBR IdeaCast (podcast), Harvard Business Review Group, October 13, 2022.
  • 25 Apr 2023
  • Op-Ed

How SHEIN and Temu Conquered Fast Fashion—and Forged a New Business Model

the internet has enabled high-income consumer markets that respond to direct-to-consumer branding and low-cost producer markets that respond to data-driven coordination, more tightly coordinated models of global View Details
Keywords: by John Deighton; Fashion; Retail; Consumer Products
  • 03 Jan 2019
  • Research & Ideas

Everyone Knows Innovation is Essential to Business Success—Except Board Directors

attracting top talent,” says Cheng. “I don’t want to discount the day-to-day concerns board members deal with, but they don’t seem to match up with the critical issues we see covered in the popular press.” The researchers wrote up their findings in a Harvard View Details
Keywords: by Michael Blanding
  • January 2008 (Revised August 2009)
  • Module Note

Competing through Business Models (C): Interdependence, Tactical & Strategic Interaction

By: Ramon Casadesus-Masanell and Joan E. Ricart
Keywords: Business Model; Competition
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Casadesus-Masanell, Ramon, and Joan E. Ricart. "Competing through Business Models (C): Interdependence, Tactical & Strategic Interaction." Harvard Business School Module Note 708-476, January 2008. (Revised August 2009.)
  • July 2013 (Revised July 2015)
  • Background Note

Innovating in Health Care—Framework

By: Regina E. Herzlinger
Contains the framework for the second-year Innovating in Health Care course. Delineates the role of six exogenous forces on new ventures: structure, financing, regulations, consumers, accountability, technology, and public policy and presents the essential elements of... View Details
Keywords: Health Care and Treatment; Management; Health Industry
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Herzlinger, Regina E. "Innovating in Health Care—Framework." Harvard Business School Background Note 314-017, July 2013. (Revised July 2015.)
  • June 2018
  • Case

Relax (Boston): Innovating and Growing an Entrepreneurial Business

By: Paul Marshall and Carole Carlson
The Relax case traces the history of a massage services company from its founding in 2007 to mid-2017, when it is considering the best strategy for growth and an acquisition. The company's owner and top managers wonder how the firm should reorganize to cope with the... View Details
Keywords: Growth and Development Strategy; Growth Management; Acquisition; Brands and Branding; Entrepreneurship; Organizational Design
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Marshall, Paul, and Carole Carlson. "Relax (Boston): Innovating and Growing an Entrepreneurial Business." Harvard Business School Brief Case 918-523, June 2018.
  • Article

What Evolution Can Teach Us About Innovation

By: Noubar Afeyan and Gary P. Pisano
Many people believe that the process for achieving breakthrough innovations is chaotic, random, and unmanageable. But that view is flawed, the authors argue. Breakthroughs can be systematically generated using a process modeled on the principles that drive evolution in... View Details
Keywords: Breakthrough Innovation; Variance Generation; Selection Pressure; Emergent Discovery; Innovation and Invention; Value Creation; Innovation Leadership
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Afeyan, Noubar, and Gary P. Pisano. "What Evolution Can Teach Us About Innovation." Harvard Business Review 99, no. 5 (September–October 2021): 62–72.
  • 2012
  • Article

Organization Design for Business Ecosystems

By: Carliss Y. Baldwin

The modern corporation has long been the central focus of the field of organization design. Such firms can be likened to nation-states: they have boundaries that circumscribe citizen-employees, and they engage in production and trade. But individual corporations are... View Details

Keywords: Modularity; Business Ecosystems; Distributed Innovation; Problem Solving; Property Rights; Organization Design; Networks; Integration; Competition; Organizational Design; Innovation and Management
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Baldwin, Carliss Y. "Organization Design for Business Ecosystems." Special Issue on The Future of Organization Design. Journal of Organization Design 1, no. 1 (2012).
  • March 2020
  • Technical Note

Intrapreneurship: Leading Innovation Efforts in Established Organizations

By: Karen G. Mills and Annie Dang
“Intrapreneurship” is the use of entrepreneurial management techniques within established companies to create new environments that foster innovation. Mature firms have consistently faced risk of elimination from competitors, shifting consumer preferences, and... View Details
Keywords: Intrapreneurship; Innovation; Corporate Venture Capital; Accelerators; Incubators; Lean Startup; Hypothesis Testing; Business Ventures; Entrepreneurship; Innovation and Invention; Leadership; Framework; Disruption
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Mills, Karen G., and Annie Dang. "Intrapreneurship: Leading Innovation Efforts in Established Organizations." Harvard Business School Technical Note 820-096, March 2020.
  • April 2019
  • Supplement

Innovation and Business in Emerging Markets: Fadi Ghandour

By: G. Jones, Tarun Khanna and Nataliya Langbird Wright
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Jones, G., Tarun Khanna, and Nataliya Langbird Wright. "Innovation and Business in Emerging Markets: Fadi Ghandour." Harvard Business School Multimedia/Video Supplement 319-715, April 2019.
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