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  • All HBS Web  (10,030)
    • People  (18)
    • News  (2,547)
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  • May–June 2018
  • Article

Data Uncertainty in Markov Chains: Application to Cost-Effectiveness Analyses of Medical Innovations

By: Joel Goh, Mohsen Bayati, Stefanos A. Zenios, Sundeep Singh and David Moore
Cost-effectiveness studies of medical innovations often suffer from data inadequacy. When Markov chains are used as a modeling framework for such studies, this data inadequacy can manifest itself as imprecision in the elements of the transition matrix. In this paper,... View Details
Keywords: Markov Chains; Cost Effectiveness; Medical Innovations; Colorectal Cancer; Health Care and Treatment; Cost vs Benefits; Innovation and Invention; Mathematical Methods; Health Industry
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Goh, Joel, Mohsen Bayati, Stefanos A. Zenios, Sundeep Singh, and David Moore. "Data Uncertainty in Markov Chains: Application to Cost-Effectiveness Analyses of Medical Innovations." Operations Research 66, no. 3 (May–June 2018): 697–715. (Winner, 2014 INFORMS Health Applications Society Pierskalla Award & Finalist, 2014 INFORMS George E. Nicholson student paper competition.)
  • 2016
  • Book

Building the Future: Big Teaming for Audacious Innovation

By: Amy C. Edmondson and Susan Salter Reynolds
Machiavelli famously wrote, "There is nothing more difficult to take in hand, more perilous to conduct, or more uncertain in its success than to take the lead in the introduction of a new order of things." That's what this book is about—innovation far more audacious... View Details
Keywords: Teaming; Innovation; Leadership; Groups and Teams; Innovation and Invention
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Edmondson, Amy C., and Susan Salter Reynolds. Building the Future: Big Teaming for Audacious Innovation. Berrett-Koehler Publishers, 2016.
  • 2016
  • Working Paper

Does Firm Innovation Affect Corporate Social Responsibility?

By: Rui Shen, Yi Tang and Ying Zhang
This study examines the relationship between firm innovation and CSR. Stakeholders’ concern over transaction-specific investments exacerbates when firms engage heavily in innovation activities. To secure stakeholders’ support, firms adopt CSR effectively as an ex ante... View Details
Keywords: Corporate Social Responsibility; Firm Innovation; Transaction-specific Investments; Firm Risk; Environmental Munificence; Corporate Social Responsibility and Impact; Business and Stakeholder Relations; Innovation and Invention
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Shen, Rui, Yi Tang, and Ying Zhang. "Does Firm Innovation Affect Corporate Social Responsibility?" Harvard Business School Working Paper, No. 16-096, February 2016.
  • March 2020
  • Case

SRS and the Defense Innovation Unit: Rethinking Procurement

By: Paul A. Gompers and David Lane
SRS and the Defense Innovation Unit (DIU) follows the process by which SRS, a lean maker of remotely-operated submersible vehicles, navigates the DIU’s acquisition process. Set up in 2015 to speed the U.S. military’s access to promising commercial technologies, the DIU... View Details
Keywords: Procurement; Defense Innovation Unit; Business Startups; Acquisition; Technological Innovation; Investment; Commercialization; United States
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Gompers, Paul A., and David Lane. "SRS and the Defense Innovation Unit: Rethinking Procurement." Harvard Business School Case 220-047, March 2020.
  • Article

Frame Flexibility: The Role of Cognitive and Emotional Framing in Innovation Adoption by Incumbent Firms

By: Ryan Raffaelli, Mary Ann Glynn and Michael Tushman
Why do incumbent firms frequently reject nonincremental innovations? Beyond technical, structural, or economic factors, we propose an additional factor: the degree of the top management team's (TMT) frame flexibility, i.e., their capability to cognitively expand an... View Details
Keywords: Innovation Adoption; Cognition; Framing; Emotional Resonance; Incumbent Inertia; Innovation and Invention; Technology Adoption; Organizational Change and Adaptation; Change Management
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Raffaelli, Ryan, Mary Ann Glynn, and Michael Tushman. "Frame Flexibility: The Role of Cognitive and Emotional Framing in Innovation Adoption by Incumbent Firms." Strategic Management Journal 40, no. 7 (July 2019): 1013–1039.
  • 2010
  • Working Paper

The Evolution of Science-Based Business: Innovating How We Innovate

By: Gary P. Pisano
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Pisano, Gary P. "The Evolution of Science-Based Business: Innovating How We Innovate." Harvard Business School Working Paper, No. 10-062, January 2010.
  • 2020
  • Working Paper

Immigration Policy Levers for U.S. Innovation and Startups

By: William R. Kerr and Sari Pekkala Kerr
Immigrants account for about a quarter of U.S. invention and entrepreneurship despite a policy environment that is not well suited for these purposes. This chapter reviews the U.S. immigration policy environment that governs how skilled migrants move to America for... View Details
Keywords: Invention; Innovation; Startups; High-tech; Immigration; Entrepreneurship; Innovation and Invention; Business Startups; Venture Capital; United States
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Kerr, William R., and Sari Pekkala Kerr. "Immigration Policy Levers for U.S. Innovation and Startups." Harvard Business School Working Paper, No. 20-105, April 2020.
  • Article

Scaling Up Analogical Innovation with Crowds and AI

By: Aniket Kittur, Lisa Yu, Tom Hope, Joel Chan, Hila Lifshitz - Assaf, Karni Gilon, Felicia Ng, Robert Kraut and Dafna Shachaf
Analogy—the ability to find and apply deep structural patterns across domains—has been fundamental to human innovation in science and technology. Today there is a growing opportunity to accelerate innovation by moving analogy out of a single person’s mind and... View Details
Keywords: Innovation; Artificial Intelligence; Crowdsourcing; Analogy; Innovation and Invention; Technology; Science
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Kittur, Aniket, Lisa Yu, Tom Hope, Joel Chan, Hila Lifshitz - Assaf, Karni Gilon, Felicia Ng, Robert Kraut, and Dafna Shachaf. "Scaling Up Analogical Innovation with Crowds and AI." Proceedings of the National Academy of Sciences 116, no. 6 (February 5, 2019): 1870–1877.
  • 2019
  • Book

Creative Construction: The DNA of Sustained Innovation

By: Gary P. Pisano
Creative Construction tackles the myth that larger enterprises are inherently incapable of transformative innovation and are doomed to be disrupted by nimble start-ups. If larger enterprises seem incapable of transformative innovation, it is due to how we design... View Details
Keywords: Innovation and Invention; Business Growth and Maturation; Innovation Strategy; Organizational Culture; Management Systems; Creativity; Leading Change
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Pisano, Gary P. Creative Construction: The DNA of Sustained Innovation. New York: PublicAffairs, 2019.
  • Article

Financing Innovation

By: William R. Kerr and Ramana Nanda
We review the recent literature on the financing of innovation, inclusive of large companies and new startups. This research strand has been very active over the past five years, generating important new findings, questioning some long-held beliefs, and creating its... View Details
Keywords: Entrepreneurship; Borrowing and Debt; Innovation and Invention
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Kerr, William R., and Ramana Nanda. "Financing Innovation." Annual Review of Financial Economics 7 (2015): 445–462.
  • May 29, 2018
  • Article

A Study of NASA Scientists Shows How to Overcome Barriers to Open Innovation

By: Hila Lifshitz - Assaf, Michael Tushman and Karim R. Lakhani
Keywords: Open Innovation; Nasa
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Lifshitz - Assaf, Hila, Michael Tushman, and Karim R. Lakhani. "A Study of NASA Scientists Shows How to Overcome Barriers to Open Innovation." Harvard Business Review (website) (May 29, 2018).
  • October 27, 2022
  • Article

4 Types of Innovators Every Organization Needs

By: Andy Wu, Goran Calic and Min Basadur
Every company strives to be innovative, but most are missing key ingredients. How can you identify which ingredients your organization needs — and which employee styles can fill in the gaps? The authors’ research distills four key innovation styles that can lead to... View Details
Keywords: Innovation Leadership; Innovation and Management
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Wu, Andy, Goran Calic, and Min Basadur. "4 Types of Innovators Every Organization Needs." Harvard Business Review (website) (October 27, 2022).
  • August 2012 (Revised August 2024)
  • Module Note

Evaluating the Viability of Innovative Technology-Commercializing Ventures

By: Regina E. Herzlinger
A guide for how a person who is not an expert in either technology nor business can, nevertheless, exaluate whether two promising innovative medical technologies are technically and/or financially feasible. Hint: I would not invest in either. View Details
Keywords: Medical Devices and Supplies Industry
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Herzlinger, Regina E. "Evaluating the Viability of Innovative Technology-Commercializing Ventures." Harvard Business School Module Note 313-070, August 2012. (Revised August 2024.)
  • Article

What Evolution Can Teach Us About Innovation

By: Noubar Afeyan and Gary P. Pisano
Many people believe that the process for achieving breakthrough innovations is chaotic, random, and unmanageable. But that view is flawed, the authors argue. Breakthroughs can be systematically generated using a process modeled on the principles that drive evolution in... View Details
Keywords: Breakthrough Innovation; Variance Generation; Selection Pressure; Emergent Discovery; Innovation and Invention; Value Creation; Innovation Leadership
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Afeyan, Noubar, and Gary P. Pisano. "What Evolution Can Teach Us About Innovation." Harvard Business Review 99, no. 5 (September–October 2021): 62–72.
  • September 2015 (Revised February 2023)
  • Case

Emdeon's Acquisition of Change Healthcare: Innovating Transparency Solutions for Health Care Consumers

By: Regina E. Herzlinger, Jeet Guram and Aanchal Raj
Case describes acquisition of Change Healthcare, which provides health care cost and quality information, by Emdeon, a health information exchange, and discusses health care transparency. Emdeon is a billion-dollar company that has grown through acquisitions; at its... View Details
Keywords: Healthcare; Healthcare Industry; Healthcare Innovation; Health Care and Treatment; Acquisition; Integration; Analytics and Data Science; Mergers and Acquisitions; Competitive Strategy; Health Industry; United States
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Herzlinger, Regina E., Jeet Guram, and Aanchal Raj. "Emdeon's Acquisition of Change Healthcare: Innovating Transparency Solutions for Health Care Consumers." Harvard Business School Case 316-026, September 2015. (Revised February 2023.)
  • 18 Nov 2016
  • Working Paper Summaries

Innovation Network

Keywords: by Daron Acemoglu, Ufuk Akcigit, and William Kerr; Technology
  • 2001
  • Other Unpublished Work

Clusters of Innovation Initiative: Wichita

By: Michael E. Porter
This study contains a conceptual framework for assessing the competitiveness of regional economies, an analysis of the Wichita region overall, as well as detailed assessments of two representative clusters—aerospace vehicles and defense and plastics. The report... View Details
Keywords: Clusters; Economics; Industry Clusters; Economy; Growth and Development; Industrial Products Industry; Aerospace Industry; Kansas
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Porter, Michael E. "Clusters of Innovation Initiative: Wichita." Council on Competitiveness, Washington, DC, October 2001. (Report.)
  • February 2007 (Revised May 2007)
  • Background Note

Accidental Innovation

Describes the role accident has historically played in invention and discovery, and raises questions about the importance of variation in business innovation processes. View Details
Keywords: Business Processes; Innovation and Invention
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Austin, Robert D., Lee Devin, and Erin Sulllivan. "Accidental Innovation." Harvard Business School Background Note 607-082, February 2007. (Revised May 2007.)
  • October 11, 2016
  • Article

Innovation Network

By: Daron Acemoglu, Ufuk Akcigit and William R. Kerr
Technological progress builds upon itself, with the expansion of invention in one domain propelling future work in linked fields. Our analysis uses 1.8 million U.S. patents and their citation properties to map the innovation network and its strength. Past innovation... View Details
Keywords: Innovation and Invention; Networks; Patents
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Acemoglu, Daron, Ufuk Akcigit, and William R. Kerr. "Innovation Network." Proceedings of the National Academy of Sciences 113, no. 41 (October 11, 2016).
  • Article

Intermediary Functions and the Market for Innovation in Meiji and Taisho Japan

By: Tom Nicholas and Hiroshi Shimizu
Japan experienced a transformational phase of technological development during the late nineteenth and early twentieth centuries. We argue that an important, but so far neglected, factor was a developing market for innovation and a patent attorney system that was... View Details
Keywords: Innovation; Patents; Innovation and Invention; Japan
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Nicholas, Tom, and Hiroshi Shimizu. "Intermediary Functions and the Market for Innovation in Meiji and Taisho Japan." Business History Review 87, no. 1 (Spring 2013): 121–150.
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