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Show Results For
- All HBS Web
(3,605)
- People (9)
- News (661)
- Research (1,894)
- Events (21)
- Multimedia (24)
- Faculty Publications (1,121)
- November 2016
- Supplement
Alnylam Pharmaceuticals: Building Value from the IP Estate (B)
By: Vicki Sato, Willy Shih and Matt Higgins
The leader of a pioneering biotech company in the siRNA space weighs his options for scaling production capacity in advance of an anticipated commercial launch. Operational complexity and relative merits of in-house manufacturing versus a contractor model are... View Details
Keywords: Pharmaceutical Companies; Pharmaceutical Industry; Biotech; Biotechnology; Operational Complexity; Strategy; Manufacturing; Production; Strategic Planning; Intellectual Property; Biotechnology Industry; United States
Sato, Vicki, Willy Shih, and Matt Higgins. "Alnylam Pharmaceuticals: Building Value from the IP Estate (B)." Harvard Business School Supplement 617-022, November 2016.
- April 2014
- Case
Merrimack Pharmaceuticals, Inc. (A)
By: Amy C. Edmondson, Bethany S. Gerstein and Melissa Valentine
In 2006, Merrimack Pharmaceuticals was a fast-growing biotechnology company. Its leadership team was divided over whether to keep R&D organized in functional departments or transition to interdisciplinary teams. As a small company, Merrimack's R&D organization had... View Details
Keywords: Teamwork; Interdisciplinary Collaboration; R&D; Biotechnology; Complexity; Innovation Management; Organizational Design; Groups and Teams; Collaborative Innovation and Invention; Research and Development; Biotechnology Industry; Pharmaceutical Industry
Edmondson, Amy C., Bethany S. Gerstein, and Melissa Valentine. "Merrimack Pharmaceuticals, Inc. (A)." Harvard Business School Case 614-063, April 2014.
- September 2015 (Revised July 2016)
- Case
Turkish Airlines: Widen Your World
By: Juan Alcácer and Esel Çekin
This case tracks Turkish Airlines' transition from regional player to global powerhouse. With an order for 212 aircraft in the first half of 2013, the airline had moved to double its size and become one of the industry's top-ten players. Growing its fleet would allow... View Details
Keywords: Strategy; Operational Complexity; Capacity Constraints; Profitable Growth; Subsidiary Management; Externalities; Emerging Market; Globalized Firms and Management; Competition; Air Transportation; Alliances; Corporate Strategy; Emerging Markets; Growth and Development Strategy; Air Transportation Industry; Turkey
Alcácer, Juan, and Esel Çekin. "Turkish Airlines: Widen Your World." Harvard Business School Case 716-408, September 2015. (Revised July 2016.)
- Article
Testing Substitutability
By: John William Hatfield, Nicole Immorlica and Scott Duke Kominers
We provide an algorithm for testing the substitutability of a length-N preference relation over a set of contracts X in time O(|X|3⋅N3). Access to the preference relation is essential for this result: We show that a substitutability-testing algorithm with access only... View Details
Keywords: Substitutability; Matching; Communication Complexity; Preference Elicitation; Marketplace Matching; Communication; Mathematical Methods; Economics
Hatfield, John William, Nicole Immorlica, and Scott Duke Kominers. "Testing Substitutability." Games and Economic Behavior 75, no. 2 (July 2012): 639–645.
- October 2019
- Article
Partial Deregulation and Competition: Effects on Risky Mortgage Origination
By: Marco Di Maggio, Amir Kermani and Sanket Korgaonkar
We exploit the OCC's preemption of national banks from state laws against predatory lending as a quasi-experiment to study the effect of deregulation and its interaction with competition on the supply of complex mortgages. Following the preemption ruling, national... View Details
Keywords: Great Recession; Subprime; Complex Mortgages; Credit Supply; Household Debt; Preemption Rule; Competition; Mortgages; Government Legislation; Credit; Financial Crisis
Di Maggio, Marco, Amir Kermani, and Sanket Korgaonkar. "Partial Deregulation and Competition: Effects on Risky Mortgage Origination." Management Science 65, no. 10 (October 2019).
- 2012
- Working Paper
Modularity and Organizations
Modularity describes the degree to which a complex system can be broken apart into subunits (modules) that can be recombined in various ways. Modularity is important for organizations and the economy because the boundaries of organizational units and corporations are... View Details
- 2015
- Working Paper
Moving to the Adjacent Possible: Discovering Paths for Export Diversification in Rwanda
By: Ricardo Hausmann and Jasmina Chauvin
How can Rwanda, which currently has one of the lowest levels of income and exports per capita in the world, grow and diversify its economy in presence of significant constraints? We analyze Rwanda's historical growth and trade performance and find that Rwanda's high... View Details
Keywords: Export Diversification; Industrialization; Economic Complexity; International Trade; Rwanda; Diversification; Trade; Transportation; Developing Countries and Economies; Rwanda
Hausmann, Ricardo, and Jasmina Chauvin. "Moving to the Adjacent Possible: Discovering Paths for Export Diversification in Rwanda." Center for International Development at Harvard University Working Paper, No. 24, April 2015.
- December 7, 2022
- Article
Why Decentralized Crypto Platforms Are Weathering the Crash
By: Shai Bernstein and Scott Duke Kominers
In the past year, crypto markets dropped from $2.9 trillion in value to around $800 billion. In the wake of the collapse, crypto lenders and exchanges have been accused of fraud and other wrongdoing. What went wrong? One factor is competition. In theory, competition... View Details
Keywords: Crypto Economy; Cryptocurrency; Financial Complexity; Financial Crisis; Decentralization; Decentralized Markets; Decentralized Autonomous Organizations; Finance; Market Design; Financial Services Industry
Bernstein, Shai, and Scott Duke Kominers. "Why Decentralized Crypto Platforms Are Weathering the Crash." Harvard Business Review Digital Articles (December 7, 2022).
- September 2016 (Revised July 2018)
- Case
United Airlines: More Out-and-Back Flying?
This case looks at United Airlines when it is facing a decision on whether to shift its aircraft routing to more "out-and-back" routing in order to try to improve its on-time performance. As one of the world's largest airlines, United had a very large fleet and... View Details
Keywords: Service Excellence; Service Management; Service Quality; Service Quality Competition; Services; Airline Industry; Airlines; Operational Complexity; Operational Disruptions; Operational Effectiveness; Operations Improvement; Operations Management; Operations Strategy; Air Transportation; Operations; Service Operations; Service Delivery; Performance Effectiveness; Performance Improvement; Complexity; Air Transportation Industry; United States
Buell, Ryan W., Willy Shih, and Mike Toffel. "United Airlines: More Out-and-Back Flying?" Harvard Business School Case 617-010, September 2016. (Revised July 2018.)
- November 2016
- Supplement
Irregular Operations
This video shows a dispatcher responding to an irregular operations situation caused by weather at an East Coast airport. View Details
Keywords: Service; Service Excellence; Service Quality; Operating Systems; Operational Complexity; Operational Disruptions; Operational Efficiency; Operational Focus; Air Transportation; Service Operations; Service Delivery; Air Transportation Industry
Buell, Ryan W., Willy C. Shih, and Michael W. Toffel. "Irregular Operations." Harvard Business School Multimedia/Video Supplement 617-705, November 2016.
- September 2016 (Revised August 2018)
- Supplement
United Airlines: More Out-and-Back Flying?: Case Supplement #1
This spreadsheet supplement accompanies 617-010 United Airlines: More Out-and-Back Flying? and is intended to provide students with an opportunity to apply analysis concepts with real operational data. View Details
- July 2013
- Case
Novozymes: Establishing the Cellulosic Ethanol Value Chain
By: Willy Shih and Sen Chai
As the world's largest producer of industrial enzymes, Novozymes had invested heavily for many years to bio-engineer enzymes that could break down cellulose into fermentable sugar. In 2010, the company had launched what it thought would become a breakthrough product... View Details
Keywords: System Complexity; Industrial Enzymes; Ethanol; Collulosic Ethanol; Fermentation; Genomics; Genetic Engineering; Value Chain; Assembling Value Chain; Energy Sources; Renewable Energy; Collaborative Innovation and Invention; Innovation and Management; Innovation Strategy; Technological Innovation; Management; Growth and Development Strategy; Industry Growth; Production; Research; Research and Development; Science; Genetics; Natural Environment; Environmental Sustainability; Science-Based Business; Business Strategy; Commercialization; Vertical Integration; Agriculture and Agribusiness Industry; Biotechnology Industry; Energy Industry; Denmark; United States
Shih, Willy, and Sen Chai. "Novozymes: Establishing the Cellulosic Ethanol Value Chain." Harvard Business School Case 614-001, July 2013.
- November 2016
- Supplement
United Airlines Operations
This video is a collection of clips that highlight aspects of United Airlines' operations View Details
Keywords: Service; Service Delivery; Service Management; Service Operations; Service Quality; Operating Systems; Operational Complexity; Operational Disruptions; Operational Effectiveness; Operational Efficiency; Air Transportation; Operations; Air Transportation Industry
Buell, Ryan W., Willy C. Shih, and Michael W. Toffel. "United Airlines Operations." Harvard Business School Multimedia/Video Supplement 617-704, November 2016.
- 2016
- Working Paper
The Mirroring Hypothesis: Theory, Evidence and Exceptions
By: Lyra J. Colfer and Carliss Y. Baldwin
The mirroring hypothesis predicts that organizational ties within a project, firm, or group of firms (e.g., communication, collocation, employment) will correspond to the technical patterns of dependency in the work being performed. A thorough understanding of the... View Details
Keywords: Modularity; Innovation; Product And Process Development; Organization Design; Design Structure; Organizational Ties; Mirroring Hypothesis; Industry Architecture; Product Architecture; Complex Technical Systems; Information Technology; Organizational Design; Organizational Structure; Relationships; Innovation and Invention; Product Development
Colfer, Lyra J., and Carliss Y. Baldwin. "The Mirroring Hypothesis: Theory, Evidence and Exceptions." Harvard Business School Working Paper, No. 16-124, April 2016. (Revised May 2016.)
- 30 Apr 2021
- Research & Ideas
Why Anger Makes a Wrongly Accused Person Look Guilty
A co-worker accuses you of lying during an important client meeting, and you’re furious because you didn’t lie. Expressing that anger, however, isn’t the best way to prove your innocence, according to new research. “People may misinterpret that anger as a sign of... View Details
Keywords: by Michael Blanding
- 06 Oct 2023
- Book
Yes, You Can Radically Change Your Organization in One Week
The biggest, thorniest organizational problems can be solved in just one week, say Frances Frei and Anne Morriss, coauthors of the new book Move Fast and Fix Things. Armed with decision-making power and the right change-management toolkit, leaders don’t need to work... View Details
Keywords: by Kristen Senz
- 06 Jun 2011
- Research & Ideas
Why Leaders Lose Their Way
In recent months several high-level leaders have mysteriously lost their way. Dominique Strauss-Kahn, former head of the International Monetary Fund and a leading French politician, was arraigned on charges of sexual assault. Before that David Sokol, rumored to be... View Details
Keywords: by Bill George
- 05 Dec 2022
- What Do You Think?
How Would Jack Welch’s Leadership Style Fare in Today’s World?
orientation. Welch visited (and taught) in my General Management classroom. I both taught and watched him teach at GE’s executive development center in Crotonville, New York. I wrote and taught a case about the company. Welch, of course, was a View Details