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      • October 2010 (Revised November 2010)
      • Background Note

      Plavix: Drugs in the Age of Personalized Medicine

      By: Richard G. Hamermesh, Mara G. Aspinall and Rachel Gordon
      PIavix, one of the world's best selling drugs in 2010, appears to have a limited future. Its patent was due to expire soon, and recently new data had been discovered that indicated that a small subset of the population would be at risk for stroke, heart attack, or even... View Details
      Keywords: Health Care and Treatment; Product Positioning; Business and Government Relations; Genetics; Competitive Strategy; Pharmaceutical Industry
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      Hamermesh, Richard G., Mara G. Aspinall, and Rachel Gordon. "Plavix: Drugs in the Age of Personalized Medicine." Harvard Business School Background Note 811-001, October 2010. (Revised November 2010.)
      • July 2010
      • Case

      Metabical: Positioning and Communications Strategy for a New Weight Loss Drug

      By: John A. Quelch and Heather Beckham
      Cambridge Sciences Pharmaceuticals (CSP) expects final approval for its revolutionary weight loss drug, Metabical. Metabical will be the only weight loss drug with FDA approval that is also clinically proven to be effective for moderately overweight people. Barbara... View Details
      Keywords: Product Positioning; Marketing Communications; Product Launch; Consumer Behavior; Pharmaceutical Industry; United States
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      Quelch, John A., and Heather Beckham. "Metabical: Positioning and Communications Strategy for a New Weight Loss Drug." Harvard Business School Brief Case 104-240, July 2010.
      • July 2010
      • Teaching Note

      Metabical: Positioning and Communications Strategy for a New Weight Loss Drug (Brief Case)

      By: John A. Quelch and Heather Beckham
      Teaching note to case #4240. View Details
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      Quelch, John A., and Heather Beckham. "Metabical: Positioning and Communications Strategy for a New Weight Loss Drug (Brief Case)." Harvard Business School Teaching Note 104-241, July 2010.
      • April 2010
      • Case

      Metabical: Pricing, Packaging, and Demand Forecasting Recommendations for a New Weight Loss Drug

      By: John A. Quelch and Heather Beckham
      Metabical is a new weight loss drug from Cambridge Sciences Pharmaceuticals intended for moderately overweight individuals. In anticipation of final FDA approval, the senior director of marketing, Barbara Printup, prepares for the product launch and must make several... View Details
      Keywords: Return On Investment; Forecasting; Pricing Policies; Demand Planning; Marketing Strategy; Price; Consumer Behavior; Investment Return; Forecasting and Prediction; Product Launch; Planning; Brands and Branding; Pharmaceutical Industry
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      Quelch, John A., and Heather Beckham. "Metabical: Pricing, Packaging, and Demand Forecasting Recommendations for a New Weight Loss Drug." Harvard Business School Brief Case 104-183, April 2010.
      • April 2010
      • Teaching Note

      Metabical: Pricing, Packaging, and Demand Forecasting Recommendations for a New Weight Loss Drug (Brief Case)

      By: John A. Quelch and Heather Beckham
      Teaching Note to 4183 View Details
      Keywords: Return On Investment; Forecasting; Pricing Policies; Demand Planning; Price; Investment Return; Forecasting and Prediction
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      Quelch, John A., and Heather Beckham. "Metabical: Pricing, Packaging, and Demand Forecasting Recommendations for a New Weight Loss Drug (Brief Case)." Harvard Business School Teaching Note 104-184, April 2010.
      • March 2010 (Revised May 2012)
      • Case

      Myelin Repair Foundation: Accelerating Drug Discovery Through Collaboration

      By: Karim R. Lakhani and Paul R. Carlile
      This case presents the Myelin Repair Foundation's accelerated research collaboration model for drug discovery. It highlights the challenges of building a multi-disciplinary and multi-institutional research collaboration that is attempting to create a treatment for... View Details
      Keywords: Research and Development; Intellectual Property; Risk and Uncertainty; Strategic Planning; Collaborative Innovation and Invention; Health Disorders; Pharmaceutical Industry; Biotechnology Industry; Health Industry
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      Lakhani, Karim R., and Paul R. Carlile. "Myelin Repair Foundation: Accelerating Drug Discovery Through Collaboration." Harvard Business School Case 610-074, March 2010. (Revised May 2012.)
      • December 2009 (Revised April 2010)
      • Teaching Note

      GlaxoSmithKline: Reorganizing Drug Discovery (TN) (A) and (B)

      By: Robert S. Huckman
      Teaching Note for [605074] and [605075]. View Details
      Keywords: Restructuring; Health; Pharmaceutical Industry
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      Huckman, Robert S. "GlaxoSmithKline: Reorganizing Drug Discovery (TN) (A) and (B)." Harvard Business School Teaching Note 610-044, December 2009. (Revised April 2010.)
      • November 2009 (Revised March 2013)
      • Case

      PureCircle

      By: David E. Bell and Aldo Sesia
      In December 2008, the U.S. Food and Drug Administration (FDA) determined that high-purity Rebaudioside A (Reb A), a natural and calorie-free product that a young company named PureCircle manufactured from the Stevia plant, could be used in beverages, foods, and as a... View Details
      Keywords: Customer Relationship Management; Investment; Globalization; Leadership; Risk Management; Product Launch; Production; Performance Productivity; Business and Shareholder Relations; Food and Beverage Industry; United States
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      Bell, David E., and Aldo Sesia. "PureCircle." Harvard Business School Case 510-032, November 2009. (Revised March 2013.)
      • November 2009
      • Case

      The Explosion of Genetic Testing: Opportunities and Challenges

      By: Richard G. Hamermesh, Mara G. Aspinall and Rachel Gordon
      This case study invites the reader to consider genetic testing in several different lights. First, can the business of genetic testing be considered a disruptive innovation to the current drug therapy model as defined by Harvard Business School Professor Clay... View Details
      Keywords: Genetics; Health Care and Treatment; Health Testing and Trials; Disruptive Innovation; Business Model; Biotechnology Industry; Health Industry
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      Hamermesh, Richard G., Mara G. Aspinall, and Rachel Gordon. "The Explosion of Genetic Testing: Opportunities and Challenges." Harvard Business School Case 810-067, November 2009.
      • November 2009 (Revised March 2010)
      • Case

      Managing Drugs on the Forefront of Personalized Medicine: The Erbitux and Vectibix Story

      By: Richard G. Hamermesh, Raju Kucherlapati and Rachel Gordon
      In May 2007, Amgen Inc. (Amgen) received disappointing news from the European Medicines Agency (EMEA) that its drug Vectibix, developed to fight metastatic colorectal cancer, had been rejected. This was especially surprising news given that a similar rival drug had... View Details
      Keywords: Entrepreneurship; Governing Rules, Regulations, and Reforms; Health Testing and Trials; Marketing Strategy; Product Positioning; Genetics; Biotechnology Industry; Europe; United States
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      Hamermesh, Richard G., Raju Kucherlapati, and Rachel Gordon. "Managing Drugs on the Forefront of Personalized Medicine: The Erbitux and Vectibix Story." Harvard Business School Case 810-066, November 2009. (Revised March 2010.)
      • July 2009 (Revised May 2010)
      • Case

      Pfizer: Letter from the Chairman (A)

      By: Robert L. Simons and Natalie Kindred
      This case explores maximizing shareholder value as a goal in executive decision making. Over a period of nine years, three different Pfizer CEOs make critical decisions intended to increase shareholder value. But the results are disappointing. To allow students to... View Details
      Keywords: Decision Choices and Conditions; Corporate Accountability; Corporate Governance; Annual Reports; Business and Shareholder Relations; Value Creation; Pharmaceutical Industry; United States
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      Simons, Robert L., and Natalie Kindred. "Pfizer: Letter from the Chairman (A)." Harvard Business School Case 110-003, July 2009. (Revised May 2010.)
      • April 2009 (Revised May 2010)
      • Case

      Partners In Health: HIV Care in Rwanda

      By: Michael E. Porter, Scott S. Lee, Joseph Rhatigan and Jim Yong Kim
      In 2005, Partners in Health (PIH) was invited by the Rwandan Ministry of Health to assume responsibility for the management of public health care in two rural districts in Eastern Rwanda and create an HIV treatment program at these sites. PIH successfully implemented a... View Details
      Keywords: Developing Countries and Economies; Health Care and Treatment; Health Testing and Trials; Medical Specialties; Service Delivery; Nonprofit Organizations; Expansion; Health Industry; Rwanda
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      Porter, Michael E., Scott S. Lee, Joseph Rhatigan, and Jim Yong Kim. "Partners In Health: HIV Care in Rwanda." Harvard Business School Case 709-474, April 2009. (Revised May 2010.)
      • April 2009 (Revised November 2012)
      • Case

      Sermo, Inc.

      By: Thomas R. Eisenmann and Lars Peter Christian Nielsen
      Sermo operates the leading online professional network for physicians in the United States. Doctors use Sermo free of charge to post surveys regarding diagnostic and treatment concerns and to discuss these concerns, as well as challenges with managing their practices.... View Details
      Keywords: Entrepreneurship; Health Care and Treatment; Knowledge Sharing; Two-Sided Platforms; Conflict and Resolution; Social and Collaborative Networks; United States
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      Eisenmann, Thomas R., and Lars Peter Christian Nielsen. "Sermo, Inc." Harvard Business School Case 809-142, April 2009. (Revised November 2012.)
      • January 2009
      • Teaching Note

      Biocon: Launching a New Cancer Drug in India (TN)

      By: Sunil Gupta and Das Narayandas
      Teaching Note for [508026]. View Details
      Keywords: Product Launch; Market Timing; Price; Distribution Channels; Marketing Strategy; Health Care and Treatment; Biotechnology Industry; Pharmaceutical Industry; India
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      Gupta, Sunil, and Das Narayandas. "Biocon: Launching a New Cancer Drug in India (TN)." Harvard Business School Teaching Note 509-039, January 2009.
      • December 2008 (Revised October 2013)
      • Case

      Amylin Pharmaceuticals: Diabetes and Beyond (A)

      By: Richard G. Hamermesh and Rachel Gordon
      Ginger Graham, CEO of Amylin Pharmaceuticals, joined the company with the expectation of taking the company's signature drug, Symlin, to market. However, unforeseen regulatory challenges have put the approval process in jeopardy. At the same time, the company has a... View Details
      Keywords: Regulations; Drug Regulations; Symlin; Negotiation; Governing Rules, Regulations, and Reforms; Resource Allocation; Negotiation Deal; Product Development; Research and Development; Commercialization; Pharmaceutical Industry; United States
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      Hamermesh, Richard G., and Rachel Gordon. "Amylin Pharmaceuticals: Diabetes and Beyond (A)." Harvard Business School Case 809-011, December 2008. (Revised October 2013.)
      • March 2008
      • Case

      The Multiple Sclerosis Center of Atlanta

      By: Regina E. Herzlinger and Alfred Martin
      The Multiple Sclerosis Center of Atlanta wishes to expand beyond Georgia. The factors influencing this decision are discussed, including drug treatments currently available, and the impact of future drugs in the FDA pipeline as well as financing issues. View Details
      Keywords: Decision Choices and Conditions; Financing and Loans; Health Care and Treatment; Health Disorders; Medical Specialties; Expansion; Health Industry; Atlanta
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      Herzlinger, Regina E., and Alfred Martin. "The Multiple Sclerosis Center of Atlanta." Harvard Business School Case 308-085, March 2008.
      • March 2008
      • Case

      Novartis AG: Science-Based Business

      By: H. Kent Bowen and Courtney Purrington
      Novartis is a science-based drug company, which has important implications for its business strategy. It is one of the largest pharmaceutical companies in the world with over $38B in sales in 2007. Pharmaceuticals account for slightly over $24B of that total. In 2007,... View Details
      Keywords: Innovation and Invention; Resource Allocation; Product Development; Partners and Partnerships; Research and Development; Science-Based Business; Pharmaceutical Industry
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      Bowen, H. Kent, and Courtney Purrington. "Novartis AG: Science-Based Business." Harvard Business School Case 608-136, March 2008.
      • 2008
      • Case

      Eli Lilly: Recreating Drug Discovery for the 21st Century

      By: Rebecca Henderson and C. Reavis
      Keywords: Innovation and Invention; Health Care and Treatment; Pharmaceutical Industry
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      Henderson, Rebecca, and C. Reavis. "Eli Lilly: Recreating Drug Discovery for the 21st Century." Massachusetts Institute of Technology (MIT) Case, 2008.
      • November 2007
      • Case

      Antegren: A Beacon of Hope

      By: Joshua D. Margolis, Thomas J. DeLong and Terence Heymann
      The CEO of Biogen Idec faces a set of difficult decisions regarding a promising drug for Multiple Sclerosis that is headed for early approval by the FDA. The first in a series focuses on operational decisions triggered by the drive for early approval. Sparks discussion... View Details
      Keywords: Demand and Consumers; Leadership; Ethics; Corporate Social Responsibility and Impact; Decision Choices and Conditions; Crisis Management; Health Testing and Trials; Biotechnology Industry; Pharmaceutical Industry
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      Margolis, Joshua D., Thomas J. DeLong, and Terence Heymann. "Antegren: A Beacon of Hope." Harvard Business School Case 408-025, November 2007.
      • September 2007
      • Article

      Investigative Negotiation

      By: Deepak Malhotra and Max H. Bazerman
      This article includes a one-page preview that quickly summarizes the key ideas and provides an overview of how the concepts work in practice along with suggestions for further reading. Negotiators often fail to achieve results because they channel too much effort into... View Details
      Keywords: Knowledge Acquisition; Knowledge Use and Leverage; Negotiation Process; Negotiation Tactics; Motivation and Incentives; Perspective; Pharmaceutical Industry
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      Malhotra, Deepak, and Max H. Bazerman. "Investigative Negotiation." Harvard Business Review 85, no. 9 (September 2007).
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