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      Biotechnology IndustryRemove Biotechnology Industry →

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      • February 2006 (Revised August 2006)
      • Case

      deCODE Genetics: Hunting for Genes to Develop Drugs

      By: Debora L. Spar
      In 1996, Kari Stefansson launched a new kind of biotechnology company and a whole new way of attacking diseases. Based in Iceland, his firm, deCODE Genetics, plans to identify the individual genetic markers that lead to society's most prevalent diseases. To do so, it... View Details
      Keywords: Information; Innovation Strategy; Genetics; Ethics; Health Disorders; Biotechnology Industry; Iceland
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      Spar, Debora L., and Chris Bebenek. "deCODE Genetics: Hunting for Genes to Develop Drugs." Harvard Business School Case 706-040, February 2006. (Revised August 2006.)
      • January 2006
      • Case

      Jack Strang at SequenceLabs

      By: Mukti Khaire, John J. Gabarro and Lynda M. Applegate
      How can entrepreneur manage his firm if things go wrong despite having a great idea, a solid team, and financial backing? Jack Strang founded a biotech firm with his friend Peter Evans, to develop molecular pathway-based "cures" for metabolic disorders. The idea was... View Details
      Keywords: Corporate Entrepreneurship; Business or Company Management; Venture Capital; Factories, Labs, and Plants; Business Growth and Maturation; Failure; Biotechnology Industry
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      Khaire, Mukti, John J. Gabarro, and Lynda M. Applegate. "Jack Strang at SequenceLabs." Harvard Business School Case 806-088, January 2006.
      • December 2005 (Revised July 2006)
      • Case

      Bunge: Poised for Growth

      By: David E. Bell and Mary L. Shelman
      As CEO of the world's largest oilseed processor, Alberto Weisser of Bunge must not only decide how quickly to expand in fast-growing markets of Eastern Europe and Asia, but also how best to leverage the firm's global footprint and leadership position. The firm is... View Details
      Keywords: Customer Focus and Relationships; Trade; Global Strategy; Leadership; Growth Management; Management Style; Demand and Consumers; Supply Chain; Integration; Technology; Agriculture and Agribusiness Industry; Agriculture and Agribusiness Industry; Asia; Europe
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      Bell, David E., and Mary L. Shelman. "Bunge: Poised for Growth." Harvard Business School Case 506-036, December 2005. (Revised July 2006.)
      • December 2005 (Revised August 2006)
      • Case

      Amgen Inc.'s Epogen--Commercializing the First Biotech Blockbuster Drug

      By: Felix Oberholzer-Gee and Dennis A. Yao
      Amgen Inc.'s Epogen was the first biotech blockbuster drug. Epogen helped prevent anemia, a condition that leads to severe fatigue, increased risk of cardiovascular disease, and even death. At the time, the market for Epogen, which included dialysis patients and... View Details
      Keywords: Health Care and Treatment; Strategic Planning; Competition; Patents; Innovation and Invention; Pharmaceutical Industry; Pharmaceutical Industry; United States
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      Oberholzer-Gee, Felix, and Dennis A. Yao. "Amgen Inc.'s Epogen--Commercializing the First Biotech Blockbuster Drug." Harvard Business School Case 706-454, December 2005. (Revised August 2006.)
      • November 2005 (Revised November 2005)
      • Case

      Massachusetts General Hospital and the Enbrel Royalty

      By: David S. Scharfstein and Darren R. Smart
      Massachusetts General Hospital is considering selling its royalty interest in Enbrel, Amgen's blockbuster drug for the treatment of rheumatoid arthritis. In assessing whether to sell, and at what price, the hospital must determine its value to a potential buyer as well... View Details
      Keywords: Valuation; Price; Investment Return; Capital; Value; Revenue; Health Care and Treatment; Health Industry; Health Industry; Massachusetts
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      Scharfstein, David S., and Darren R. Smart. "Massachusetts General Hospital and the Enbrel Royalty." Harvard Business School Case 206-075, November 2005. (Revised November 2005.)
      • June 2005 (Revised July 2006)
      • Background Note

      Note on the Convergence Between Genomics & Information Technology

      By: David B. Yoffie, Dharmesh M Mehta and Rachel Sha
      Focuses on the convergence between the genomics and semiconductor industries, in particular organ printing, DNA computing, biomolecular sensory networks, and DNA microarrays. Explains what this newly converged world looks like based on current research and findings in... View Details
      Keywords: Genetics; Information Technology; Business Model; Disruptive Innovation; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry; Biotechnology Industry
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      Yoffie, David B., Dharmesh M Mehta, and Rachel Sha. "Note on the Convergence Between Genomics & Information Technology." Harvard Business School Background Note 705-500, June 2005. (Revised July 2006.)
      • December 2004 (Revised July 2005)
      • Case

      Extend Fertility

      By: Myra M. Hart and Sylvia Sensiper
      Focuses on the search for opportunity, the generation and evaluation of business concepts, creation of a business plan, and the start-up process. Follows experienced entrepreneur Christy Jones as she combines her business skills and personal experience to generate new... View Details
      Keywords: Opportunities; Business Plan; Entrepreneurship; Personal Development and Career; Social Issues; Gender; Business Startups; Biotechnology Industry
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      Hart, Myra M., and Sylvia Sensiper. "Extend Fertility." Harvard Business School Case 805-065, December 2004. (Revised July 2005.)
      • October 2004 (Revised March 2005)
      • Case

      Langer Lab, The: Commercializing Science

      By: H. Kent Bowen, Alex Kazaks, Ayr Muir-Harmony and Bryce LaPierre
      Professor Robert Langer's laboratory at MIT is the source of an unusually large number of published papers, patents, and technology licenses to start-up and established companies in the biomedical industry. Explores Langer's leadership and other factors that create a... View Details
      Keywords: Entrepreneurship; Technological Innovation; Business Startups; Research and Development; Patents; Innovation Leadership; Science-Based Business; Commercialization; Biotechnology Industry; Biotechnology Industry
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      Bowen, H. Kent, Alex Kazaks, Ayr Muir-Harmony, and Bryce LaPierre. "Langer Lab, The: Commercializing Science." Harvard Business School Case 605-017, October 2004. (Revised March 2005.)
      • May 2004
      • Teaching Note

      Monsanto: Technology Cooperation and Small Holder Farmer Projects (TN)

      By: James E. Austin and Diana Barrett
      Teaching Note to (9-302-068). View Details
      Keywords: Biotechnology Industry
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      Austin, James E., and Diana Barrett. "Monsanto: Technology Cooperation and Small Holder Farmer Projects (TN)." Harvard Business School Teaching Note 304-108, May 2004.
      • 2004
      • Chapter

      Genzyme's Gaucher Initiative: Global Risk and Responsibility

      By: Christopher A. Bartlett and Andrew N. McLean
      Keywords: Health Disorders; Corporate Social Responsibility and Impact; Globalization; Risk and Uncertainty; Health Industry; Health Industry
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      Bartlett, Christopher A., and Andrew N. McLean. "Genzyme's Gaucher Initiative: Global Risk and Responsibility." Chap. 22 in Problems and Cases in Health Care Marketing, edited by John T. Gourville, John A. Quelch, and V. Kasturi Rangan, 411–434. New York: McGraw-Hill/Irwin, 2004.
      • December 2003 (Revised April 2004)
      • Case

      Dragon's Teeth Vineyards

      By: Alan D. MacCormack, Marius Leibold, Sven Voelpel and Kerry Herman
      Dragon's Teeth Vineyards (DTV) is a South African wine producer that is considering whether to use genetically modified organisms (GMOs) in its wine-making process. GMOs promise to lower the costs of wine production significantly through increased yields and reduced... View Details
      Keywords: Technological Innovation; Growth and Development Strategy; Genetics; Transition; Brands and Branding; Product Development; Product Design; Organizational Change and Adaptation; Technology Adoption; Food and Beverage Industry; Food and Beverage Industry; South Africa
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      MacCormack, Alan D., Marius Leibold, Sven Voelpel, and Kerry Herman. "Dragon's Teeth Vineyards." Harvard Business School Case 604-069, December 2003. (Revised April 2004.)
      • September 2003 (Revised August 2005)
      • Teaching Note

      Calgene, Inc. (TN)

      By: John T. Gourville
      Teaching Note for (9-502-041) View Details
      Keywords: Biotechnology Industry; Biotechnology Industry
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      Gourville, John T. "Calgene, Inc. (TN)." Harvard Business School Teaching Note 504-045, September 2003. (Revised August 2005.)
      • June 2003 (Revised October 2004)
      • Case

      Novartis: The Challenge of Success (C)

      By: Sandra J. Sucher and Stacy McManus
      Supplements the (A) and (B) cases. View Details
      Keywords: Pharmaceutical Industry; Pharmaceutical Industry
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      Sucher, Sandra J., and Stacy McManus. "Novartis: The Challenge of Success (C)." Harvard Business School Case 603-045, June 2003. (Revised October 2004.)
      • June 2003 (Revised October 2004)
      • Case

      Novartis: The Challenge of Success (D)

      By: Sandra J. Sucher and Stacy McManus
      Supplements the (A) and (B) cases. View Details
      Keywords: Pharmaceutical Industry; Pharmaceutical Industry
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      Sucher, Sandra J., and Stacy McManus. "Novartis: The Challenge of Success (D)." Harvard Business School Case 603-046, June 2003. (Revised October 2004.)
      • June 2003 (Revised March 2008)
      • Case

      Schering-Plough and Genome Therapeutics: Discovering an Asthma Gene

      By: Regina E. Herzlinger and Marc Aquino
      Personalized medicine requires the identification of mutated genes. Schering-Plough's search for the one related to asthma requires finding families with the disease. Examines the industry that helps conduct such research, including contract research organizations. View Details
      Keywords: Health Disorders; Research and Development; Genetics; Biotechnology Industry; Biotechnology Industry
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      Herzlinger, Regina E., and Marc Aquino. "Schering-Plough and Genome Therapeutics: Discovering an Asthma Gene." Harvard Business School Case 303-044, June 2003. (Revised March 2008.)
      • April 2003 (Revised October 2004)
      • Case

      Novartis: The Challenge of Success (A)

      By: Sandra J. Sucher and Stacy McManus
      Preliminary results from Phase 1 clinical trials of a newly developed compound, STI571, showed that 31 out of 31 patients with chronic myelogenous leukemia (CML) had their blood counts return to normal. In the world of oncology, this was unheard of. This was the... View Details
      Keywords: Decision Making; Health Testing and Trials; Innovation and Invention; Markets; Distribution; Product Development; Production; Problems and Challenges; Research; Research and Development; Complexity; Biotechnology Industry; Biotechnology Industry
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      Sucher, Sandra J., and Stacy McManus. "Novartis: The Challenge of Success (A)." Harvard Business School Case 603-043, April 2003. (Revised October 2004.)
      • April 2003 (Revised October 2004)
      • Case

      Novartis: The Challenge of Success (B)

      By: Sandra J. Sucher and Stacy McManus
      When Dr. Daniel Vasella learned of the early Phase 1 trial results, he immediately decided what course of action Novartis would take. Students will be able to examine and assess the concrete steps, and the rationale behind them, that Novartis took in response to this... View Details
      Keywords: Decision Making; Moral Sensibility; Innovation and Invention; Distribution; Product Development; Production; Problems and Challenges; Research and Development; Biotechnology Industry; Biotechnology Industry
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      Sucher, Sandra J., and Stacy McManus. "Novartis: The Challenge of Success (B)." Harvard Business School Case 603-044, April 2003. (Revised October 2004.)
      • Article

      Do Equity Financing Cycles Matter?: Evidence from Biotechnology Alliances

      By: Josh Lerner, Hilary Shane and Alexander Tsai
      Keywords: Equity; Financing and Loans; Science; Alliances; Biotechnology Industry
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      Lerner, Josh, Hilary Shane, and Alexander Tsai. "Do Equity Financing Cycles Matter?: Evidence from Biotechnology Alliances." Journal of Financial Economics 67, no. 3 (March 2003): 411–446. (Earlier versions distributed as HBS Working Paper No. 00-038 and NBER Working Paper No. 7464.)
      • February 2003
      • Article

      Which Ties Matter When? The Contingent Effects of Interorganizational Partnerships on IPO Success

      By: Ranjay Gulati and M. Higgins
      This paper investigates the contingent value of interorganizational relationships at the time of a young firm's initial public offering (IPO). We compare the signaling value to young firms of having ties with two types of interorganizational partnerships: endorsement... View Details
      Keywords: Interorganizatonal Relationships; Networks; Venture Capital; Initial Public Offering; Entrepreneurship; Biotechnology Industry
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      Gulati, Ranjay, and M. Higgins. "Which Ties Matter When? The Contingent Effects of Interorganizational Partnerships on IPO Success." Strategic Management Journal 24, no. 2 (February 2003): 127–144.
      • Article

      Discontinuities and Senior Management: Assessing the Role of Recognition in Pharmaceutical Firm Response to Biotechnology

      By: Rebecca M. Henderson, Sarah Kaplan and Fiona Murray
      Keywords: Management; Science; Technology; Biotechnology Industry
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      Henderson, Rebecca M., Sarah Kaplan, and Fiona Murray. "Discontinuities and Senior Management: Assessing the Role of Recognition in Pharmaceutical Firm Response to Biotechnology." Industrial and Corporate Change 12, no. 2 (April 2003).
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