Publications

2024
Working Paper

Chimeric Antigen Receptor T-Cell Therapy—Living Drugs: Case Histories of Transformational Advances

By: Amar Bhidé and Srikant M. Datar

In 2017, the US Food and Drug Administration (FDA) approved an immunotherapeutic treatment, called CAR-T therapy, for two kinds of blood cancers—acute leukemia (ALL) and a lymphoma. We describe 1) how CAR-T works, 2) the foundational advances and discoveries, 3) the... View Details

Keywords: Immunotherapy; Health Care and Treatment; Innovation and Invention; Research and Development; Governing Rules, Regulations, and Reforms

SSRN

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April 2010
Article

Managed Globalization: Doctrine, Practice, and Promise

By: Rawi Abdelal and Sophie Meunier

Two alternate visions for shaping and explaining the governance of economic globalization have been in competition for the past 20 years: an ad hoc, laissez-faire vision promoted by the United States versus a managed vision relying on multilateral rules and... View Details

Keywords: Financial Crisis; Trade; Globalized Economies and Regions; Governing Rules, Regulations, and Reforms; Competition; European Union; United States

01 Dec 2010
News

Iron Lady

OTEH: “Local and international investors need to understand that things have changed” in Nigeria. On the fiftieth anniversary of Nigeria’s independence, one key player who wants to see the oil-rich country truly fulfill its promise is Arunma Oteh (MBA ’90). A former... View Details

Keywords: Finance

2015
Working Paper

The Integrity of Private Third-party Compliance Monitoring

By: Jodi L. Short and Michael W. Toffel

Government agencies are increasingly turning to private, third-party monitors to inspect and assess regulated entities’ compliance with law. The integrity of these regulatory regimes rests on the validity of the information third-party monitors provide to regulators.... View Details

SSRN

January 2009 (Revised February 2009)
Case

Sydney IVF: Stem Cell Research

By: Robert L. Simons, Kathryn Rosenberg and Natalie Kindred

This case examines the strategy implementation and risk management decisions at Sydney IVF, a research-based in vitro fertilization and stem cell company based in Australia. Drs. Robert Jansen and Jock Anderson, who co-founded Sydney IVF in 1986, developed novel... View Details

Keywords: Ethics; Governing Rules, Regulations, and Reforms; Innovation and Management; Growth and Development Strategy; Risk Management; Genetics; Commercialization; Health Industry; Australia

September 2004 (Revised April 2005)
Case

U.S. Market Framework for Gasoline, The: Individual Incentives and Societal Goals in Global Markets

By: Bruce R. Scott and Edward Murphy

Traces the role of gasoline taxes in financing U.S. highways and the use of regulations to increase fuel economy to show how and why the U.S. market framework for gasoline is so different from that in Europe. Focuses on whether the U.S. tax should be raised, as... View Details

Keywords: Taxation; Governing Rules, Regulations, and Reforms; Energy Sources; Digital Platforms; Sovereign Finance; Growth and Development Strategy; United States; Europe

01 Dec 2008
News

A U.S. Turnaround?

electronics industries were developing momentum. We took our leadership for granted, ignored this shift, and became complacent. Our problems became more serious when communism failed in Russia, Chairman Mao died, and reforms that were... View Details

Keywords: Byron Wien; Performing Arts, Spectator Sports, and Related Industries; Arts, Entertainment; Computer and Electronic Product Manufacturing; Manufacturing; Transportation Equipment Manufacturing; Manufacturing; Electric Power Generation, Transmission, Distribution; Utilities

September 2019 (Revised January 2020)
Case

Gun Safety in America: Three Leaders Propose Innovative Solutions

By: Rosabeth Moss Kanter and Joseph Paul

Gun violence was a significant problem in America. Three Harvard Advanced Leadership Initiative Fellows Christy Wood, Russell Sternlicht, and Gareth Glaser each decided to do something about gun safety. They each used their professional and leadership experience to... View Details

February 2012
Article

Management Practices across Firms and Countries

By: Nicholas Bloom, Christos Genakos, Raffaella Sadun and John Van Reenen

For the last decade we have been using double-blind survey techniques and randomized sampling to construct management data on over 10,000 organizations across 20 countries. On average, we find that in manufacturing American, Japanese, and German firms are the best... View Details

Keywords: Management Practices and Processes; Competency and Skills; Governing Rules, Regulations, and Reforms; Organizations; Developing Countries and Economies; Economic Sectors; Performance; Business and Shareholder Relations; Private Equity; Multinational Firms and Management; United States; Germany; Japan; China; India

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08 Aug 2016
Working Paper Summaries

The Unintended Consequences of the Zero Lower Bound Policy

Keywords: by Marco Di Maggio and Marcin Kacperczyk; Banking

November 2022 (Revised March 2023)
Case

OneSmart

By: Nien-he Hsieh, Meg Rithmire and Shu Lin

At the end of 2021, Xi “Steve” Zhang was facing an existential crisis for himself and his business. OneSmart was a premium educational company founded in 2008 offering K-12 afterschool tutoring for students nationwide under a number of brands. The company was founded... View Details

Keywords: Governing Rules, Regulations, and Reforms; Crisis Management; Failure; Education Industry; China

March 2021
Article

The Effectiveness of White-Collar Crime Enforcement: Evidence from the War on Terror

By: Trung Nguyen

This paper analyzes the impact of changes in regulatory priorities and resource allocation on criminal enforcement of white‐collar criminal activities. Using the 9/11 terrorist attacks as a shock to the FBI's priorities and allocation of investigative resources, as... View Details

Keywords: White-collar Crime; Government Regulation; Financial Fraud; Securities Fraud; Insider Trading; Crime and Corruption; Finance; Governing Rules, Regulations, and Reforms; Law Enforcement

July 2019
Article

The Impact of Price Regulation on the Availability of New Drugs in Germany

By: Ariel Dora Stern, Felicitas Pietrulla, Annika Herr, Aaron S. Kesselheim and Ameet Sarpatwari

The 2011 German Pharmaceutical Market Restructuring Act (“AMNOG”) subjected branded, non-rare disease drugs to price regulation based on an assessment of their clinical benefit. Assessment outcomes range from “major added benefit” to “less benefit than the appropriate... View Details

Keywords: Regulation; Pharmaceuticals; Healthcare; Health Care and Treatment; Price; Governing Rules, Regulations, and Reforms; Pharmaceutical Industry; Germany

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November 2010
Teaching Note

Saudi Arabia: Modern Reform, Enduring Stability. Dubai: Global Economy (TN)

By: Richard H.K. Vietor

Teaching Note for 709042 and 709043. View Details

Keywords: Economy; Governing Rules, Regulations, and Reforms; Globalization; Balance and Stability; Saudi Arabia; Dubai