Publications

Web

Latin America - Global

greatly increased the volume of in-depth research and course materials that focus on business management issues specific to Latin American companies. This has also enabled HBS to strengthen its relationships with important companies and... View Details

December 2006 (Revised August 2008)
Case

Pervasis Therapeutics, Inc.

By: Robert F. Higgins and Virginia Fuller

In May 2005, Steve Bollinger was about to become president and chief operating officer of Pervasis Therapeutics, a small cell therapy start-up in Cambridge, Mass. If proven successful, Pervasis' product, Vascugel, could change the way vascular disease is treated and... View Details

Keywords: Business Startups; Venture Capital; Financial Strategy; Governing Rules, Regulations, and Reforms; Health Care and Treatment; Health Testing and Trials; Health Industry; Cambridge

March 2011 (Revised February 2012)
Case

Innovation and Growth at Actelion Ltd.

By: Gary P. Pisano, Daniela Beyersdorfer and Ruth Dittrich

In late 2010, Jean-Paul Clozel, CEO of the Swiss biotech pharmaceuticals firm Actelion, looks back on a successful decade. The small venture that he had started with a few of his scientist colleagues in the late 1990s to discover novel medicine in a research-driven... View Details

Keywords: Business Model; Talent and Talent Management; Innovation and Management; Leadership; Growth and Development Strategy; Product Development; Organizational Culture; Research and Development; Biotechnology Industry; Pharmaceutical Industry; Switzerland

01 Dec 2023
News

Wide Horizon

There were three critical events that led John Rodakis (MBA 1997) to form the nonprofit N of One in 2014 and ultimately dedicate his life to surfacing breakthrough autism research. The first occurred on Thanksgiving of 2012. He had driven about four hours with his wife... View Details

Keywords: Dan Morrell; Photos by Sarah Wilson

2011
Book

Detour: My Unexpected, Amazing, Life Changing Journey With OnStar

By: Chet Huber

Detour is the story behind the launch of OnStar’s now well known blue button, as told through the eyes of its founder and CEO of over fourteen years, Chet Huber. It’s a personal narrative that describes the events that led up to General Motors’ unexpected choice... View Details

Keywords: General Motors; OnStar; Technological Innovation; Business Startups; Transportation; Safety; Personal Development and Career; Creativity; Success; Business History; Auto Industry

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20 Nov 2017
Research & Ideas

How Independent Bookstores Have Thrived in Spite of Amazon.com

promotion of independent bookstores. But then a funny thing happened. While pressure from Amazon forced Borders out of business in 2011, indie bookstores staged an unexpected comeback. Between 2009 and 2015, the ABA reported a 35 percent... View Details

Keywords: by Carmen Nobel (with video by Amelia Kunhardt); Retail

04 Mar 2014
Sharpening Your Skills

Sharpening Your Skills: Managing Innovation

"innovation is everyone's job." Dozens of faculty at Harvard Business School are focused on the subject of managing innovation. Some look at it by examining processes while others view through the lens of history. For example, Clay... View Details

Keywords: Re: Multiple Faculty

24 Oct 2018
Sharpening Your Skills

Startup or Established Company? Which Is Best for You?

people to hire to run them so once the flywheel is moving and cash is in hand, they can get momentum quickly. “Earlier in my career, I hired a small team within a large corporation that was scrappy and had entrepreneurial mentality. At my... View Details

Keywords: by Julia B. Austin

June 1995 (Revised June 1995)
Case

Ernst & Young United Kingdom (A)

By: John J. Gabarro and Samantha Graff

Intended to be a robust example of the challenges encountered during the early stages of a large-scale organizational transformation effort in a professional service firm. Describes a massive change program initiated and led by the new managing partner along with a... View Details

Keywords: Restructuring; Change Management; Leading Change; Management Teams; Organizational Change and Adaptation; Problems and Challenges; United Kingdom; London

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August 2003 (Revised August 2024)
Case

Fighting the Battle of the Bulge—Evaluating Do Good/Do Well Innovations in Morbid Obesity Treatment

By: Regina E. Herzlinger and John McDonough

Many health care innovations appear successful; but fail. This is the first case in the Innovating Health Care course that investigates how to create successful health care innovations. It is part of the first module in the course. This module focuses on how to... View Details

Keywords: Three Pillars; Industry Analysis; Health Care and Treatment; Innovation and Invention; Innovation and Management; Medical Specialties; Health Industry

02 Apr 2024
Research & Ideas

Employees Out Sick? Inside One Company's Creative Approach to Staying Productive

Absenteeism is so pervasive in Latin America and Asia that 10 percent of a business’ workers might not show up on any given day. This risk can create tremendous uncertainty, especially for businesses running on low margins, says Jorge... View Details

Keywords: by Michael Blanding; Fashion

Web

Entrepreneurship - Faculty & Research

over small changes in their collective interest levels to implement a regression discontinuity approach. We confirm the positive effects for venture operations, with qualitative support for a higher likelihood of successful exits. On the... View Details

01 Sep 2023
News

That Was Then, This Is Now

It started with a question. But before that, it started in the classroom. Tony Deifell (MBA 2002) loved the discussions in his LEAD course, taught by Professor (and now former Dean) Nitin Nohria; wanting to make them more tangible, Deifell adapted the idea of... View Details

Keywords: Photographed by Tony Deifell (MBA 2002); edited by Julia Hanna. Above: Heidi Brooks, photographed in 2003 and 2023.; life experience; family; leadership

February 2009 (Revised April 2011)
Case

Mistry Architects (A)

By: Amy C. Edmondson, Robert G. Eccles and Mona Sinha

Describes an architecture firm founded and run by a husband and wife team, Sharukh and Renu Mistry, that emphasizes "green" building. The firm presents an unusual mix of projects-spanning the spectrum from larger corporate projects to small private homes. The mix also... View Details

Keywords: Family Business; Customer Focus and Relationships; Design; Housing; Corporate Social Responsibility and Impact; Business and Community Relations; Environmental Sustainability; Nonprofit Organizations; Conflict and Resolution